Modulation of granulocyte-macrophage colony-stimulating factor gene expression by a tumor necrosis factor α specific ribozyme in juvenile myelomonocytic leukemic cells

Blood

Volumn 92, Issue 11, 1998, Pages 4263-4268

  Iversen, Per Ole ^a   Sioud, Mouldy ^b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RIBOZYME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CHILD; CHILDHOOD LEUKEMIA; COLONY FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MYELOMONOCYTIC LEUKEMIA; PRIORITY JOURNAL;

EID: 0032402145     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.11.4263.422k46_4263_4268     Document Type: Article

References (34)

1. Castro-Malaspina H, Schaison G, Passe S, Pasquier A, Berger R, Bayle-Weisgerber C, Miller D, Seligmann M, Bernard J: Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Cancer 54:675, 1984
2. Arico M, Biondi A, Pui C-H: Juvenile myelomonocytic leukemia. Blood 90:479, 1997
3. Niemeyer CM, Arico M, Basso G, Biondi A, Rajnoldi AC, Creutzig U, Haas O, Harbott J, Hasle H, Kerndrup G, Locatelli F, Mann G, Stollmann-Gibbels B, van't Veer-Korthof ET, van Wering E, Zimmermann M, and members of the European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS); Chronic myelomonocytic leukemia in childhood: A retrospective analysis of 110 cases. Blood 89:3534, 1997
4. Hasle H, Kerndrup G, Jacobsen BB: Childhood myelodysplastic syndrome in Denmark: Incidence and predisposing conditions. Leukemia 9:1569, 1995
5. Chan HSL, Estrov Z, Weitzman SS, Freedman MH: The value of intensive combination chemotherapy for juvenile chronic myelogeneous leukemia. J Clin Oncol 5:1960, 1987
6. Hasle H, Kerndrup G, Yssing M, Clausen N, Ostergaard E, Jacobsen N, Jacobsen BB: Intensive chemotherapy in childhood myelodysplastic syndrome. A comparison with results in acute myeloid leukemia. Leukemia 10:1269, 1996
7. Sanders JE, Buckner CD, Thomas ED, Fleisher R, Sullivan KM, Appelbaum FA, Storb R: Allogeneic marrow transplantation for children with juvenile chronic myelogenous leukemia. Blood 71:1144, 1988
8. Katz F, Hann I, Kinsey S, Ball S, Morgan G, Chessells J: Assessment of graft status following allogenic bone marrow transplantation for haematological disorders in children using locus-specific minisatellite probes. Br J Haematol 83:473, 1993
9. Miyauchi J, Atsada M, Sasuki M, Tsunematsu Y, Kojima S, Mizutani S: Mutations of the N-ras gene in juvenile chronic myelogenous leukemia. Blood 83:2248, 1994
10. ras. Blood 84:3435, 1994
11. Largaespada DA, Brannan CI, Jenkins NA, Copeland NG: Nf1 deficiency causes ras-mediated granulocyte-macrophage colony-stimulating factor hypersensitivity and chronic leukaemia. Nat Genet 12:137, 1996
12. Bollag G, Clapp DW, Shih S, Adler F, Zhang YY, Thompson P, Lange BJ, Freedman MH, McCormick F, Jacks T, Shannon K: Loss of NF1 results in activation of the ras signaling pathway and leads to abberant growth in haematopoietic cells. Nat Genet 12:144, 1996
13. Satoh T, Nakafuku M, Miyajima A, Kaziro Y: Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4. Proc Natl Acad Sci USA 88:3314, 1991
14. Emanuel PD, Bates LJ, Castleberry RP, Gualtieri RJ, Zuckerman KS: Selective hypersensitivity to granulocyte-macrophage colonystimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors. Blood 77:925, 1991
15. Gualtieri RJ, Emanuel PD, Zuckerman KS, Martin G, Clark SC, Shadduck RK, Dracker RA, Akabutu J, Nitschke R, Hetherington ML, Dickerman JD, Hakami N, Castleberry RP: Granulocyte-macrophage colony-stimulating factor is an endogeneous regulator of cell proliferation in juvenile chronic myelogenous leukemia. Blood 74:2360, 1989
16. Emanuel PD, Bates LJ, Zhu S-W, Castleberry RP, Gualtieri RJ, Zuckerman KS: The role of monocyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia. Exp Hematol 19:1017, 1991
17. Freedman MH, Cohen A, Grunberger T, Bunin N, Luddy RE, Saunders EF, Shahidi N, Lau A, Estrov Z: Central role of tumour necrosis factor, GM-CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogeneous leukaemia. Br J Haematol 80:40, 1992
18. Iversen PO, Rodwell RL, Pitcher L, Taylor KM, Lopez AF: Inhibition of proliferation and induction of apoptosis in juvenile myelomonocytic leukemic cells by the granulocyte-macrophage colonystimulating factor analogue E21R. Blood 88:2634, 1996
19. Iversen PO, Hart PH, Bonder CS, Lopez AF: Interleukin-(IL-) 10, but not IL-4 or IL-13, inhibits cytokine production and growth in juvenile myelomonocytic leukemic cells. Cancer Res 57:476, 1997
20. Lapidot T, Grunberger T, Vormoor J, Estrov Z, Kollet O, Bunin N, Zaizov R, Williams DE, Freedman MH: Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice. Blood 88:2655, 1996
21. Iversen PO, Lewis ID, Turczynowicz S, Hasle H, Niemeyer C, Schmiegelow K, Bastiras S, Blondi A, Hughes IP, Lopez AF: Inhibition of granulocyte-macrophage colony-stimulating factor prevents dissemination and induces remission of juvenile myelomonocytic leukemia in engrafted immunodeficient mice. Blood 90:4910, 1997
22. Uhlenbeck OC: A small catalytic oligonucleotide. Nature 328: 596, 1987
23. Haseloff J, Gerlach WL: Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature 334:585, 1988
24. Cameron FH, Jennings PA: Specific gene suppression by engineered ribozymes in monkey cells. Proc Natl Acad Sci USA 83:8859, 1989
25. Sarver N, Cantin EM, Chang PS, Zaia JA, Ladne PA, Stephens DA, Rossi JJ: Ribozymes as potential and HIV-1 therapeutic agents. Science 247:1222, 1990
26. Sioud M, Drlica K: Prevention of HIV-1 integrase expression in E.coli by a ribozyme. Proc Natl Acad Sci USA 88:7303, 1991
27. Sioud M: Interaction between tumor necrosis factor a ribozyme and cellular proteins. J Mol Biol 242:619, 1994
28. Metcalf D, Begley CG, Johnson GR, Nicola NA, Vadas MA, Lopez AF, Williamson DJ, Wong GG, Clark SC, Wang EA: Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor. Blood 67:37, 1986
29. Kochetkova M, Iversen PO, Lopez AF, Shannon MF: Deoxyribonucleic acid triplex formation inhibits granulocyte-macrophage colonystimulating factor gene expression and suppresses growth in juvenile myelomonocytic leukemic cells. J Clin Invest 99:3000, 1997
30. Bagby GC Jr, Dinarello CA, Neerhout RC, Ridgway D, McCall E: Interleukin 1-dependent paracrine granulopoiesis in chronic granulocytic leukemia of the juvenile type. J Clin Invest 82:1430, 1988
31. Sioud M: Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo. Eur Immunol 26:1026, 1996
32. Drouet C, Shakhov AN, Jongeneel CV: Enhancers and transcription factors controlling the inducibility of the TNFα promoter in primary macrophages. J Immunol 147:1694, 1991
33. Freeburn RW, Gale RE, Wagner HM, Linch DC: Analysis of the coding sequence for the GM-CSF receptor α and β chains in patients with juvenile chronic myeloid leukemia (JCML). Exp Hematol 25:306, 1997
34. Side L, Taylor B, Cayouette M, Conner E, Thompson P, Luce M, Shannon K: Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders. N Engl J Med 336:1713, 1997