Functional evidence for involvement of multiple putative tumor suppressor genes on the short arm of chromosome 3 in human oral squamous cell carcinogenesis

Cancer Genetics and Cytogenetics

Volumn 107, Issue 2, 1998, Pages 125-131

  Uzawa, Narikazu ^a   Yoshida, Mitsuaki A ^a   Hosoe, Shigeto ^b   Oshimura, Mitsuo ^c   Amagasa, Teruo ^a   Ikeuchi, Tatsuro ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENESIS; CELL CLONE; CHROMOSOME 3P; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYBRID CELL; MOUSE; MOUTH CARCINOMA; NONHUMAN; NUDE MOUSE; PHENOTYPE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TONGUE CANCER; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 3; GENES, TUMOR SUPPRESSOR; HUMANS; HYBRID CELLS; MICE; MICE, NUDE; MOUTH NEOPLASMS; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 0032400889     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(98)00097-1     Document Type: Article

References (39)

1. Oshimura M., Kugoh H., Koi M., Shimizu M., Yamada H., Satoh H., Barrett J.C. Transfer of a normal human chromosome 11 suppresses tumorigenicity of some but not all tumor cell lines. J Cell Biochem. 42:1990;135-142.
2. Trent J.M., Stanbridge E.J., McBride H.L., Meese E.U., Casey G., Araujo D.E., Witkowski C.M., Nagle R.B. Tumorigenicity in human melanoma cell lines controlled by introduction of human chromosome 6. Science. 247:1990;568-571.
3. Goyette M.C., Cho K., Fasching C.L., Levy D.B., Kinzler K.W., Paraskeva C., Vogelstein B., Stanbridge E.J. Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Mol Cell Biol. 12:1992;1387-1395.
4. Yoshida M.A., Shimizu M., Ikeuchi T., Tonomura A., Yokota J., Oshimura M. In vitro growth suppression and morphological change in a human renal cell carcinoma cell line by the introduction of normal chromosome 3 via microcell fusion. Mol Carcinog. 9:1994;114-121.
5. Uzawa N., Yoshida M.A., Oshimura M., Ikeuchi T. Suppression of tumorigenicity in three different cell lines of human oral squamous cell carcinoma by introduction of chromosome 3p via microcell-mediated chromosome transfer. Oncogene. 11:1995;1997-2004.
6. Vokes E.E., Weichselbaum R.R., Lippman S.M., Hong W.K. Head and neck cancer. N Engl J Med. 328(3):1993;184-194.
7. Sakai E., Rikimaru K., Ueda M., Matsumoto Y., Ishii N., Enomoto S., Yamamoto H., Tsuchida N. The p53 tumor-suppressor gene and ras oncogene mutations in oral squamous-cell carcinoma. Int J Cancer. 52:1992;867-872.
8. Uzawa K., Yoshida H., Suzuki H., Tanzawa H., Shimazaki J., Seino S., Sato K. Abnormalities of the adenomatous polyposis coli gene in human oral squamous-cell carcinoma. Int J Cancer. 58:1994;814-817.
9. Somers K.D., Cartwright S.L., Schechter G.L. Amplification of the int-2 gene in human head and neck squamous cell carcinomas. Oncogene. 5:1990;915-920.
10. Sreekantaiah C., Rao P.H., Xu L., Sacks P.G., Schantz S.P., Chaganti R.S.K. Consistent chromosome losses in head and neck squamous cell carcinoma cell lines. Genes Chromosom Cancer. 11:1994;29-39.
11. Maestro R., Gasparotto D., Vukosavljevic T., Barzan L., Sulfaro S., Boiocchi M. Three discrete regions of deletion at 3p in head and neck cancers. Cancer Res. 53:1993;5775-5779.
12. Wu C.L., Sloan P., Read A.P., Harris R., Thakker N. Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma of the oral cavity. Cancer Res. 54:1994;6484-6488.
13. Nawroz H., van der Riet P., Hruban R.H., Koch W., Ruppert J.M., Sidransky D. Allelotype of head and neck squamous cell carcinoma. Cancer Res. 54:1994;1152-1155.
14. El-Naggar A.K., Hurr K., Batsakis J.G., Luna M.A., Goepfert H., Huff V. Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. Cancer Res. 55:1995;2656-2659.
15. Rowley H., Jones A., Spandidos D., Field J. Definition of a tumor suppressor locus on the short arm of chromosome 3 in squamous cell carcinoma of head and neck by means of microsatellite markers. Arch Otolaryngol Head Neck Surg. 122:1996;497-501.
16. Momose F., Araida T., Negishi A., Ichijo H., Shioda S., Sasaki S. Variant sublines with different metastatic potentials selected in nude mice from human oral squamous cell carcinomas. J Oral Pathol Med. 18:1989;391-395.
17. Shimizu M., Yokota J., Mori N., Shuin T., Shioda M., Terada M., Oshimura M. Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR. Oncogene. 5:1990;185-194.
18. Koi M., Morita H., Yamada H., Satoh H., Barrett J.C., Oshimura M. Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa. Mol Carcinog. 2:1989;12-21.
19. Southern E.M. Detection of sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 98:1975;503-517.
20. Jones M., Nakamura Y. Deletion mapping of chromosome 3p in female genital tract malignancies using microsatellite polymorphisms. Oncogene. 7:1992;1631-1634.
21. Kholodnyuk I., Kost-Alimova M., Kashuba V., Gizatulin R., Szeles A., Stanbridge E.J., Zabarovsky E.R., Klein G., Imreh S. A 3p21.3 region is preferentially eliminated from human chromosome 3/mouse microcell hybrids during tumor growth in SCID mice. Genes Chromosom Cancer. 18:1997;200-211.
22. van den Berg A., Buys C.H.M.C. Involvement of multiple loci on chromosome 3 in renal cell cancer development. Genes Chromosom Cancer. 19:1997;59-76.
23. Kok K., Naylor S.L., Buys C.H.C.M. Deletion of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv Cancer Res. 71:1997;27-92.
24. Koi M., Johnson L.A., Kalikin L.M., Little P.F.R., Nakamura Y., Feinberg A.P. Tumor cell growth arrest caused by subchromosomal transferable DNA fragments from chromosome 11. Science. 260:1993;361-364.
25. Murakami Y.S., Brothman A.R., Leach R.J., White R.L. Suppression of malignant phenotype in a human prostate cancer cell line by fragments of normal chromosomal region 17q. Cancer Res. 55:1995;3389-3394.
26. Ohta M., Inoue H., Cotticelli G.M., Kastury K., Baffa R., Palazzo J., Siprashvill Z., Mori M., McCue P., Druck T., Croce C.M., Huebner K. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell. 84:1996;587-597.
27. Virgilio L., Shuster M., Golin S.M., Veronese M.L., Ohta M., Huebner K., Croce C.M. FHIT gene alterations in head and neck squamous cell carcinomas. Proc Natl Acad Sci USA. 93:1996;9770-9775.
28. Mao L., Fan Y.-H., Lotan R., Hong W.K. Frequent abnormalities of FHIT, a candidate tumor suppressor gene, in head and neck cancer cell lines. Cancer Res. 56:1996;5128-5131.
29. Sozzi G., Veronese M.L., Negrini M., Baffa R., Cotticelli M.G., Inoue H., Tornielli S., Pilotti S., De Gregorio L., Pastorino U., Pierotti M.A., Ohta M., Huebner K., Croce C.M. The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell. 85:1996;17-25.
30. Negrini M., Monaco C., Vorechovsky I., Ohta M., Druck T., Baffa R., Huebner K., Croce C.M. The FHIT gene at 3p14.2 is abnormal in breast carcinomas. Cancer Res. 56:1996;3173-3179.
31. van den Berg A., Draaijers T.G., Kok K., Timmer T., van der Veen A.Y., Veldhuis P.M.J.F., de Leij L., Gerhartz C.D., Naylor S.L., Smith D.I., Buys C.H.M.C. Normal FHIT transcripts in renal cell cancer- and lung cancer-derived cell lines, including a cell line with a homozygous deletion in the FRA3B region. Genes Chromosom Cancer. 19:1997;220-227.
32. Latif F., Tory K., Gnarra J., Yao M., Duh F., Orcutt M., Stackhouse S., Kuzmin I., Modi W., Geil L., Schmidt L., Zhou F., Li H., Wei M.H., Chen F., Glenn G., Choyke P., Walther M.M., Weng Y., Duan D.R., Dean M., Glavac D., Richards F.M., Crossey P.A., Ferguson-Smith M.L., Le Paslier D., Chumakov I., Cohen D., Chinault C.A., Maher E.R., Linehan W.M., Zbar B., Lerman M.I. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science. 260:1993;1317-1320.
33. Decker H.J.H., Weidt E.J., Brieger J. The von Hippel-Lindau tumor suppressor gene. a rare and intriguing disease opening new insight into basic mechanisms of carcinogenesis Cancer Genet Cytogenet. 93:1997;74-83.
34. Richards F.M., Payne S.J., Zbar B., Affara N.A., Ferguson-Smith M.A., Maher E.R. Molecular analysis of de novo germline mutations in the von Hippel-Lindau disease gene. Hum Mol Genet. 4:1995;2139-2143.
35. Waber P.G., Lee N.K., Nisen P.D. Frequent allelic loss at chromosome arm 3p is distinct from genetic alteration of the Von-Hippel Lindau tumor suppressor gene in head and neck cancer. Oncogene. 12:1996;365-369.
36. Uzawa K., Suzuki H., Yokoe H., Tanzawa H., Sato K. Mutation state of p16/CDKN2 and VHL genes in squamous-cell carcinoma of the oral cavity. Int J Oncol. 7:1995;895-899.
37. Mathew S., Murty V.V.V.S., Cheifetz S., George D., Massague J., Chaganti R.S.K. Transforming growth factor receptor gene TGFBR2 maps to human chromosome band 3p22. Genomics. 20:1994;114-115.
38. Garrigue-Antar L., Munoz-Antonia T., Antonia S.J., Gesmonde J., Vellucci V.F., Reiss M. Missense mutations of the transforming growth factor β type II receptor in human head and neck squamous carcinoma cells. Cancer Res. 55:1995;3982-3987.
39. Ichijo H., Momose F., Miyazono K. Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells. Exp Cell Res. 187:1990;263-269.