Fate of transforming DNA in pathogenic fungi

Medical Mycology, Supplement

Volumn 36, Issue 1, 1998, Pages 38-44

  Kwon Chung, K J ^a,e   Goldman, W E ^b   Klein, B ^c   Szaniszlo, P J ^d  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^e NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Gene disruption; Genetic transformation; Pathogenic fungi

Indexed keywords

DNA; LITHIUM ACETATE;

ASPERGILLUS FUMIGATUS; ASPERGILLUS NIDULANS; BLASTOMYCES DERMATITIDIS; CANDIDA; COCCIDIOIDES IMMITIS; CRYPTOCOCCUS NEOFORMANS; DNA INTEGRATION; EXOPHIALA; FUNGUS; GENE DISRUPTION; GENETIC ENGINEERING; GENETIC TRANSFORMATION; HISTOPLASMA CAPSULATUM; NONHUMAN; REVIEW;

DNA, FUNGAL; FUNGI; HUMANS; MYCOSES; TRANSFORMATION, GENETIC;

EID: 0032310963     PISSN: 09668454     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (43)

1. Kurtz MB, Cortelyou MW, Kirsch DR. Integrative transformation of Candida albicans using a cloned ADE2 gene. Mol Cell Biol 1986; 6: 142-9.
2. Edman JC, Kwon-Chung KJ. Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selectable marker for transformation. Mol Cell Biol 1990; 10: 4538-44.
3. Worsham PL, Goldman WE. Development of a genetic transformation system for Histoplasma capsulation: Complementation of uracil auxotrophy. Mol Gen Genet 1990; 221: 358-62.
4. Hogan LH, Klein BS. Transforming DNA integrates at multiple sites in the dimorphic fungal pathogen Blastomyces dermatitidis. Gene 1997; 186: 219-26.
5. Monod M, Paris S, Sarfati J, et al. Virulence of alkaline protease-deficient mutants of Aspergillus fumigatus. FEMS Microbiol Lett 1993; 106: 39-46.
6. Peng M, Cooper CR, Szaniszlo PJ. Genetic transformations of the pathogenic fungus Wangiella dermtitidis. AMI. App Microbiol Biotechnol 1995; 44: 444-50.
7. Williams FW, Smithson SL, Cole GT. General Meeting of the American Society for Microbiology, 1996: abstract no. F-114.
8. Eissenberg LG, Goldman WE. The interplay between Histoplasma capsulatum and its host cells. Baillière's Clin Infect Dis 1994; 1: 265-83.
9. Worsham PL, Goldman WE. Selection and characterization of ura5 mutants of Histoplasma capsulatum. Mol Gen Genet 1988; 214: 348-52.
10. Woods JP, Goldman WE. Hygromycin B resistance as a selectable marker in Histoplasma capsulatum General Meeting of the American Society for Microbiology, 1995: abst. no. F-66.
11. Woods JP, Goldman WE. Autonomous replication of foreign DNA in Histoplasma capsulatum: Role of native telomeric sequences. J Bacteriol 1993; 175: 636-41.
12. Patel JB, Batanghari JW, Goldman WE. Probing the role and regulation of the CBPI gene of Histoplasma capsulatum. General Meeting of the American Society for Microbiology, 1997; abst. no. F-18.
13. Woods JP, Heinecke EL. Homologous gene targeting in Histoplasma capsulatum: URA5 gene disruption using a hygromycin resistance marker. General Meeting of the American Society for Microbiology, 1996: abst. no. F-116.
14. Foster LAA, Goldman WE. Development of restriction enzyme-mediated integration (REMI) as an insertional mutagensis tool for Histoplasma capsulatum. General Meeting of the American Society for Microbiology, 1996: abst. no. F-115.
15. Schiesti RH, Petes TD. Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiae. Proc Nat Acad Sci USA 1991; 88: 7585-9.
16. Klein BS, Vergeront JM, Weeks RJ, et al. Isolation of Blastomyces dermatitidis in soil associated with large outbreak of blastomycosis in Wisconsin. New Eng J Med 1986; 314: 529-34.
17. Brass C, Volkmann CM, Philpott DE, et al. Spontaneous mutant of Blastomyces dermatitidis attenuated in virulence for mice. Sabouraudia 1982; 20: 145.
18. Morrison CJ, Stevens DA. Mechanisms of fungal pathogenicity: Correlation of virulence in vivo, susceptibility to killing by polymorphonuclear neutrophils in vitro, and neutrophil superoxide induction among Blastomyces dermatitidis isolates. Infect Immun 1991; 59: 2744
19. Smith TL, Gaskell J, Berka RM, et al. The promoter of the glucoamylase-encoding gene of Aspergillus niger functions in Ustilago maydis. Gene 1990; 88: 259-62.
20. Hogan LH, Josvai S, Klein BS. Genomic cloning, characterization, and functional analysis of the major surface adhesin WI-1 on Blastomyces dermatitidis yeast. J Biol Chem 1996; 270: 30725-32.
21. Edman JC. Isolation of telomere-like sequences from Cryptococcus neoformans and their use in high-efficiency transformation. Mol Cell Biol 1992; 12: 2777-83.
22. Klein BS, Hogan LH, Jones JM. Immunological recognition of a 25-amino acid repeat arrayed in tandem on a major antigen of Blastomyces dermatitidis. J Clin Invest 1993; 92: 330-7.
23. Klein BS, Jones JM. Isolation, purification and radiolabehng of a novel 120-kD surface protein on Blastomyces dermatitidis yeasts to detect antibody in infected patients. J Clin Invest 1990; 85: 152-61
24. Klein BS, Sondel PM, Jones JM. WI-1, a novel 120 kilodalton surface protein on Blastomyces dermatitidis yeast cells, is a target antigen of cell-mediated immunity in human blastomycosis. Infect Immun 1992; 60: 4291-300.
25. Newman SL, Chaturvedi S, Klein BS. The WI-1 Ag of Blastomyces dermatitidis yeasts mediates binding to human macrophage CD IIb/CD18 (CR3) and CD. J Immunol 1995; 154: 753-61.
26. Kwon-Chung KJ, Bennett JE. Medical Mycology. Philadelphia: Lea & Febiger, 1992: 397-446.
27. Toffaletti DL, Rude T, Johnston SA, Durack DT, Perfect JR. Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNA. J Bacteriol 1993; 175: 1405-1411.
28. Cox GM, Toffaletti L, Perfect JR. Dominant selection system for use in Cryptococcus neoformans. J Med Vet Mycol 1996; 34: 385-91.
29. Varma A, Kwon-Chung KJ. Molecular and genetic analysis of URA5 transformants of Cryptococcus neoformans. Infect Immun 1992; 60: 1101-8.
30. Varma A, Kwon-Chung KJ. Formation of a minichromosome in Cryptococcus neoformans as a result of electroporative transformation. Curr Genet 1994; 26: 54-61.
31. Chang YC, Kwon-Chung KJ. Complementation of a capsule deficient mutation of Cryptococcus neoforinans restores its virulence. Mol Cell Biol 1994; 14: 4912-9.
32. Matsumoto T, Ajello L, Matsuda T, Szaniszlo PJ, Walsh TJ. Developments in hyalohyphomycosis and phaeohyphomycosis. J Med Vet Mycol 1994; 32 (Suppl. 1): 329-49.
33. Szaniszlo PJ, Mendoza L, Karuppayil SM. Clues about chromoblastomycotic and other dematiaceous fungal pathogens based on Wangtella as a model. In: Vanden Bossche H, Odds FC, Kerridge D, eds. Dunorphic Fungi in Biology and Medicine. New York: Plenum Press, 1993: 241-55.
34. Punt PJ, Oliver RP, Dingemanse MA, Pouwels PH, van den Hondel CA. Transformation of Aspergillus based on the hygromycin B resistance marker from Escherichia coli. Gene 1987; 56: 117-124.
35. Vollmer SJ, Yanofsky C. Efficient cloning of genes of Neurospora crassa. Proc Nat Acad Sci USA 1986; 83: 4869-73.
36. Drocourt D, Calmels T, Reynes JP, Baron M, Tiraby G. Cassettes of the Streptoalluteichus hindustanus gene for transformation of lower and higher eukaryotes phleomycin resistance. Nuc Acids Res 1990; 18: 4009.
37. Watson JD, Gilman M, Witkowske J, Zoller M. Recombinant DNA, 2nd edn. New York: Scientific American Books, 1992.
38. Bowen AR, Chen-Wu JL, Momany M, et al. Classification of fungal chitin synthases. Proc Nat Acad Sci USA 1992; 89: 519-23.
39. Karuppayil SM, Peng M, Mendoza L, Levins TA, Szaniszlo PJ. Identification of the conserved coding sequences of three chitin synthase genes in Fonsecea pedrosoi. J Med Ver Mycol 1996; 34: 117-25.
40. Zheng L, Szaniszlo PJ. Molecular characterization of chitin synthase 2 (WdCHS2) and disruption of WdCHS1 and WdCHS2 in Wangiella dermatitidis. General Meeting of the American Society for Microbiology, 1996: abst. no. F-122.
41. Wang Z, Feng B, Szaniszlo PJ. Cloning of the class IV chitin synthase gene, WdCHS4, of Wangiella dermatitidis by a marker rescue approach. General Meeting of the American Society for Microbiology, 1997: abst. no. F-23.
42. Wang Z, Zheng L, Szaniszlo PJ. Cloning, characterization and functional study of the chitin synthase 3 (WdCHS3) gene of Wangiella dermatitidis. General Meeting of the American Society for Microbiology, 1996: abst. no. F-123.
43. Zheng L, Wang Z, Szaniszlo PJ. Construction and characterization of chitin synthase (WdCHS) double and triple gene disruption strains in Wangiella dermatitidis. General Meeting of the American Society for Micriobiology, 1997: abst. no. F-22.