Distinct roles for sphingolipids and glycosphingolipids at different stages of neuronal development

Acta Biochimica Polonica

Volumn 45, Issue 2, 1998, Pages 469-478

  Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Axons; Ceramide; Dendrites; Hippocampus; Neurons

Indexed keywords

GLYCOSPHINGOLIPID; SPHINGOLIPID;

ANIMAL; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; HIPPOCAMPUS; HUMAN; NERVE CELL; NERVOUS SYSTEM; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; GLYCOSPHINGOLIPIDS; HIPPOCAMPUS; HUMANS; NERVOUS SYSTEM; NEURONS; SPHINGOLIPIDS;

EID: 0032238867     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.1998_4240     Document Type: Review

References (33)

1. Bielawska, A., Crane, H.M., Liotta, D., Obeid, L.M. & Hannun, Y.A. (1993) Selectivity of ceramide-mediated biology: Lack of activity of erythrodihydroceramide. J. Biol. Chem. 268, 26226-26232.
2. Boldin, S. & Futerman, A.H. (1997) Glucosylceramide synthesis is required for basic fibroblast growth factor and laminin to stimulate axonal growth. J. Neurochem. 68, 882-885.
3. Chen, C.S., Rosenwald, A.G. & Pagano, R.E. (1995) Ceramide as a modulator of endocytosis. J. Biol. Chem. 270, 13291-13297.
4. Dobrowsky, R.T., Werner, M.H., Castellino, A.M., Chao, M.V. & Hannun, Y.A. (1994) Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 265, 1596-1599.
5. Dotti, C.G., Sullivan, C.A. & Banker, G.A. (1988) The establishment of polarity by hippocampal neurons in culture. J. Neurosci. 8, 1454-1468.
6. Dotti, C.G., Parton, R.G. & Simons, K. (1991) Polarized sorting of glypiated proteins in hippocampal neurons. Nature 349, 158-161.
7. Fishbein, J.D., Dobrowsky, R.T., Bielawska, A., Garrett, S. & Hannun, Y.A. (1993) Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae. J. Biol. Chem. 268, 9255-9261.
8. Furuya, S., Hashikawa, T., Irie, F., Hasegawa, A., Nakao, T. & Hirabayashi, Y. (1995) Neuronal expression of a minor monosialosyl ganglioside GMlb in rat brain: Immunochemical characterization using a specific monoclonal antibody. Neurosci. Res. 22, 411-421.
9. Furuya, S., Hashikawa, T. & Hirabayashi, Y. (1996) Restricted occurrence of an unusual ganglioside GD1 alpha in rat brain and its possible involvement in dendritic growth of cerebellar Purkinje neurons. J. Neurosci. Res. 44, 73-83.
10. Futerman, A.H., Stieger, B., Hubbard, A.L. & Pagano, R.E. (1990) Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J. Biol. Chem. 265, 8650-8657.
11. Futerman, A.H. (1994a) Ceramide metabolism is compartmentalized in the endoplasmic reticulum and Golgi apparatus. Curr. Topics in Membranes 40, 93-110.
12. Futerman, A.H. (1994b) An update on sphingolipid synthesis and transport through the secretory pathway. Trends Glycosci. Glycotechnol. 6, 143-153.
13. Futerman, A.H. & Banker, G.A. (1996) The economics of neurite growth - the addition of new membrane to the growing axon. Trends Neurosci. 19, 144-149.
14. Goslin, K. & Banker, G. (1991) Rat hippocampal neurons in low density culture; in Culturing Nerve Cells (Banker, G. & Groslin, K., esd.) pp. 251-281, MIT Press, Cambridge.
15. Hannun, Y.A. & Obeid, L.M. (1995) Ceramide: An intracellular signal for apoptosis. Trends Biochem. Sci. 20, 73-77.
16. Harel, R. & Futerman, A.M. (1993) Inhibition of sphingolipid synthesis affects axonal out-growth in cultured hippocampal neurons. J. Biol. Chem. 268, 14476-14481.
17. Hirschberg, K., Zisling, R., van Echten-Deckert, G. & Futerman, A.H. (1996) Ganglioside synthesis during the development of neuronal polarity: major changes occur during axonogenesis and axon elongation, but not during dendrite growth or during synaptogenesis. J. Biol. Chem. 271, 14876-14882.
18. Ledeen, R.W. & Yu, G. (1992) Ganglioside function in the neuron. Trends Glycosci. Glycotechnol. 4, 174-187.
19. Li, R.X. & Ladisch, S. (1997) Inhibition of endogenous ganglioside synthesis does not block neurite formation by retinoic acid-treated neuroblastoma cells. J. Biol. Chem. 272, 1349-1354.
20. Pushkareva, M., Obeid, L.M. & Hannun, Y.A. (1995) Ceramide: An endogenous regulator of apoptosis and growth suppression. Immunol. Today 16, 294-297.
21. Riboni, L., Prinetti, A., Bassi, R., Caminiti, A. & Tettamanti, G. (1995) A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation. J. Biol. Chem. 270, 26868-26875.
22. Rosenwald, A.G., Machamer, C.E. & Pagano, R.E. (1992) Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway. Biochemistry 31, 3581-3590.
23. Rosenwald, A.G. & Pagano, R.E. (1993) Inhibition of glycoprotein traffic through the secretory pathway by ceramide J. Biol. Chem. 268, 4577-4579.
24. Schwarz, A., Rapaport, E., Hirschberg, K. & Futerman, A.H. (1995) A regulatory role for sphingolipids in neuronal growth: Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching. J. Biol. Chem. 270, 10990-10998.
25. Schwarz, A. & Futerman, A.H. (1996) The localization of gangliosides in neurons of the central nervous system: The use of anti-ganglioside antibodies Biochim. Biophys. Acta 1286, 242-267.
26. Schwarz, A. & Futerman, A.H. (1997a) Determination of the localization of gangliosides using anti-ganglioside antibodies: Comparison of fixation methods J. Histochem. Cytochem. 45, 611-618.
27. Schwarz, A. & Futerman, A.H. (1997b) Distinct roles for ceramide and glucosylceramide at different stages of neuronal growth J. Neurosci. 17, 2929-2938.
28. Siegel, D.A. & Walkley, S.U. (1994) Growth of ectopic dendrites on cortical pyramidal neurons in neuronal storage diseases correlates with abnormal accumulation of GM2 ganglioside. J. Neurochem. 62, 1852-1862.
29. Simons, K. & van Meer, G. (1988) Lipid sorting in epithelial cells. Biochemistry 27, 6197-6202.
30. Sofer, A. & Futerman, A.H. (1995) Cationic amphiphilic drugs inhibit the internalization of cholera toxin to the Golgi apparatus and the subsequent elevation of cyclic AMP. J. Biol. Chem. 270, 12117-12122.
31. Sofer, A. & Futerman, A.H. (1996) Rate of retrograde transport of cholera toxin from the plasma membrane to the Golgi apparatus and endoplasmic reticulum decreases during neuronal development. J. Neurochem. 67, 2134-2140.
32. Sofer, A., Schwarzmann, G. & Futerman, A.H. (1996) The internalization of a short acyl chain analogue of ganglioside GM(1) in polarized neurons. J. Cell Sci. 109, 2111-2119.
33. Uemura, K., Sugiyama, E. & Taketomi, T. (1991) Effects of an inhibitor of glucosylceramide synthase on glycosphingolipid synthesis and neurite outgrowth in murine neuroblastoma cell lines. J. Biochem. (Tokyo) 110, 96-102.