Renal 11β-hydroxysteroid dehydrogenase in genetically salt-sensitive hypertensive rats

Hypertension

Volumn 32, Issue 6, 1998, Pages 1077-1082

  Takeda, Yoshiyu ^a   Inaba, Satoru ^b   Furukawa, Kenji ^b   Miyamori, Isamu ^b  

^a KANAZAWA UNIVERSITY   (Japan)

^b NONE

Author keywords

Glucocorticoids; Hypertension, essential; Kidney; Mineralocorticoids; Rats, Dahl; Sodium

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CORTICOSTERONE; DEHYDROCORTICOSTERONE; ENZYME INHIBITOR; GLUCOCORTICOID; KIDNEY ENZYME; MESSENGER RNA; MINERALOCORTICOID; SODIUM; HYDROXYSTEROID DEHYDROGENASE;

ADOLESCENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERTENSION; KIDNEY; KIDNEY MICROSOME; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD; COMPARATIVE STUDY; DAHL SALT SENSITIVE RAT; DRUG ANTAGONISM; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HEMODYNAMICS; METABOLISM; TIME; URINE;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; ENZYME INHIBITORS; GENE EXPRESSION; HEMODYNAMIC PROCESSES; HYDROXYSTEROID DEHYDROGENASES; HYPERTENSION; KIDNEY; POLYMERASE CHAIN REACTION; RATS; RATS, INBRED DAHL; RNA, MESSENGER; TIME FACTORS;

EID: 0032217175     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.32.6.1077     Document Type: Article

References (41)

1. Kornel L, Starnes WR, Hill SR Jr, Hill A. Studies on steroid conjugates, VI: quantitative paper chromatography of urinary corticosteroids in essential hypertension. J Clin Endocrinol Metab. 1969;29:1608-1617.
2. Walker BR, Stewart PM, Shackleton CHL, Padfield PL, Edwards CRW. Deficient inactivation of cortisol by 11β-hydroxysteroid dehydrogenase in essential hypertension. Clin Endocrinol. 1993;39:221-227.
3. Soro A, Ingram MC, Tonolo G, Glorioso N, Fraser R. Evidence of coexisting changes in 11β-hydroxysteroid dehydrogenase and 5β-reductase activity in subjects with untreated essential hypertension. Hypertension. 1995;25:67-70.
4. Takeda Y, Miyamori I, Yoneda T, Iki K, Hatakeyama H, Takeda R. Gene expression of 11β-hydroxysteroid dehydrogenase in the mesenteric arteries of genetically hypertensive rats. Hypertension. 1994;23:577-580.
5. Takeda Y, Yoneda T, Miyamori I, Gathiram P, Takeda R. 11β-Hydroxysteroid dehydrogenase activity in mesenteric arteries of spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 1993;20: 627-631.
6. Roland BL, Funder JW. Localization of 11β-hydroxysteroid dehydrogenase type 2 in rat tissues: in situ studies. Endocrinology. 1996;137: 1123-1128.
7. Souness GW, Latif SA, Laurenzo JL, Morris DJ. 11α-and 11β-Hydroxyprogesterone, potent inhibitors of 11β-hydroxysteroid dehydrogenase (isoforms 1 and 2), confer marked mineralocorticoid activity on corticosterone in the ADX rat. Endocrinology. 1995;136:1809-1812.
8. Souness GW, Morris DJ. 11α-and 11β-Hydroxyprogesterone, potent inhibitors of 11β-hydroxysteroid dehydrogenase, possess hypertensinogenic activity in the rat. Hypertension. 1996;27:421-425.
9. Takeda Y, Miyamori I, Iki K, Inaba S, Furukawa K, Hatakeyama H, Yoneda T, Takeda R. Endogenous renal 11β-hydroxysteroid dehydrogenase inhibitory factors in patients with low-renin essential hypertension. Hypertension. 1996;27:197-201.
10. Lo YH, Sheff MF, Latif SA, Ribeiro C, Silver H, Brem AS, Morris DJ. Kidney 11β-HSD2 is inhibited by glycyrrhetinic acid-like factors in human urine. Hypertension. 1997;29(pt 2):500-505.
11. Hamet P, Mongeau E, Lambert J, Bellavance F, Daignault-Gelinas M, Ledoux M, Whissell-Cambiotti L. Interactions among calcium, sodium, and alcohol intake as determinants of blood pressure. Hypertension. 1991;17(suppl I):I-150-I-154.
12. Baba K, Mulrow PJ, Franco-Saenz R, Rapp JP. Suppression of adrenal renin in Dahl salt-sensitive rats. Hypertension. 1986;8:1149-1153.
13. Gomez-Sanchez EP, Gomez-Sanchez CE. 19-Nordeoxycorticosterone excretion in male and female inbred salt-sensitive (S/JR) and salt-resistant (R/JR) Dahl rats. Endocrinology. 1988;122:1110-1113.
14. Hano T, Jeng Y, Rho J. Norepinephrine overflow and re-uptake in perfused mesenteric arteries of Dahl salt-sensitive and salt-resistant rats. J Hypertens. 1989;7:43-49.
15. Cicila GT, Rapp JP, Wang JM, Lezin ES, Ng SC, Kurtz W. Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat. Nat Genet. 1993;3:346-353.
16. Cover CM, Wang JM, Lezin ES, Kurtz TW, Mellon SH. Molecular variants in the P45011AS gene as determinants of aldosterone synthase activity in the Dahl rat model of hypertension. J Biol Chem. 1995;270: 16555-16560.
17. Miyamori I, Brown MJ, Dollery CT. Single-dose captopril administration in DOCA/salt rats: reduction of hypotensive effect by indomethacin. Clin Exp Hypertens. 1980;2:935-945.
18. Takeda Y, Lewicka S, Koch S, Bige K, Vecsei P, Abdelhamid S, Cojocaru M, Harnik M. Synthesis of 19-noraldosterone, 18-hydroxy-19-norcorticosterone and 18,19-dihydroxycorticosterone in the human aldosterone-producing adenoma. J Steroid Biochem Molec Biol. 1990;37: 599-604.
19. Stewart PM, Murry BA, Mason JI. Human kidney 11β-hydroxysteroid dehydrogenase is a high affinity nicotinamide adenine dinucleotide-dependent enzyme and differs from the cloned type I isoform. J Clin Endocrinol Metab. 1994;79:480-484.
20. Palermo M, Shackleton CHL, Mantero F, Stewart PM. Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man. Clin Endocrinol. 1996;45:605-611.
21. Whorwood CB, Ricketts ML, Stewart PM. Epithelial cell localization of type 2 11β-hydroxysteroid dehydrogenase in rat and human colon. Endocrinology. 1994;135:2533-2541.
22. +-dependent isoform of 11β-hydroxysteroid dehydrogenase. Endocrinology. 1992;131:970-972.
23. Takeda Y, Miyamori I, Yoneda T, Hatakeyama H, Inaba S, Furukawa K, Takeda R. Regulation of aldosterone synthase in human vascular endothelial cells by angiotensin II and adrenocorticotropin. J Clin Endocrinol Metab. 1996;81:2797-2800.
24. Zhou M-Y, Gomez-Sanchez EP, Cox DL, Cosby D, Gomez-Sanchez CE. Cloning, expression, and tissue distribution of the rat nicotinamide adenine dinucleotide-dependent 11β-hydroxysteroid dehydrogenase. Endocrinology. 1995;136:3729-3734.
25. Wilson RC, Harbison MD, Krozowski ZS, Funder JW, Shackleton CHL, Hanauske-Abel HM, Wei J-Q, Hertecant J, Moran A, Neiberger RE, Balfe JW, Fattah A, Daneman D, Licholai T, New MI. Several homozygous mutations in the gene for 11β-hydroxysteroid dehydrogenase type 2 in patients with apparent mineralocorticoid excess. J Clin Endocrinol Metab. 1995;80:3145-3150.
26. Mune T, Rogerson FM, Nillila H, Agarwal AK, White PC. Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase. Nat Genet. 1995;10:394-399.
27. Brem AS, Bina B, Matheson KL, Barnes JL, Morris DJ. Developmental changes in rat renal 11β-hydroxysteroid dehydrogenase. Kidney Int. 1994;45:679-683.
28. Brem AS, Bina RB, King T, Chobanian MC, Morris DJ. Influence of dietary sodium on the renal isoforms of 11β-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1997;214:340-345.
29. Franco-Saenz R, Tokita Y, Latif S, Morris DJ. 11β-Hydroxysteroid in the Dahl rat. Am J Hypertens. 1997;10:1004-1009.
30. Wilson RC, Dave-Sharma S, Wei JQ, Obeyesekere VR, Li K, Ferrari P, Krozowski ZS, New MI. A new mild form of apparent mineralocorticoid excess. In: Program and abstracts of the 79th Annual Meeting of the Endocrine Society; June 11-14, 1997; Minneapolis, Minn. Abstract:66.
31. Bravo EL, Tarazi RC, Dustan HP. The changing clinical spectrum of primary aldosteronism. Am J Med. 1983;74:641-651.
32. Conte G, Canton AD, Balletta M, Meccariello S, Sabbatini M, Andreucci VE. Mechanism of impaired urinary concentrating ability in normokalemic primary aldosteronism. Clin Nephrol. 1984;22:90-96.
33. Kudo LH, Hawk CT, Schafer JA. Sodium and water transport in cortical collecting duct of Dahl salt-resistant rat. Am J Physiol. 1994;267: F583-F591.
34. Smith RE, Maguire JA, Stein-Oafley AN, Sasano H, Takahashi K, Fukushima K, Krozowski ZS. Localization of 11β-hydroxysteroid dehydrogenase type II in human epithelial tissues. J Clin Endocrinol Metab. 1996;81:3244-3248.
35. Kornel L, Rafelson ME, Hatashi T, Kanamarlapudi N, Anderson KM. Arterial receptors for adrenal steroids and transport of electrolytes in vascular smooth muscle. Clin Physiol Biochem. 1988;6:188-200.
36. Takeda Y, Miyamori I, Inaba S, Furukawa K, Hatakeyama H, Yoneda T, Mubuchi H, Takeda R. Vascular aldosterone in genetically hypertensive rats. Hypertension. 1997;29:45-48.
37. Tobian L, Redleaf PD. Effect of hypertension on arterial wall electrolytes during deoxycorticosterone administration. Am J Physiol. 1957;189: 451-454.
38. Morris DJ, Semafuko WEB, Latif SA, Vogel B, Grimes CA, Sheff MF. Detection of glycyrrhetinic acid-like factors (GALFS) in human urine. Hypertension. 1992;20:346-360.
39. Walker BR, Aggarwal ILA, Stewart PM, Padfield PL, Edwards CRW. Endogenous inhibitors of 11β-hydroxysteroid dehydrogenase in hypertension. J Clin Endocrinol Metab. 1995;80:529-533.
40. Walker BR, Williamson PM, Brown MA, Honour JW, Edwards CRW, Whitworth JA. 11β-Hydroxysteroid dehydrogenase and its inhibitors in hypertensive pregnancy. Hypertension. 1995;25:626-630.
41. Semafuko WEB, Sheff MF, Grimes CA, Latif SA, Sadaniantz A, Levinson P, Morris DJ. Inhibitors of 11β-hydroxysteroid dehydrogenase and 5β-steroid reductase in urine from patients with congestive heart failure. Ann Clin Lab Sci. 1993;23:456-461.