Molecular mechanisms of vestibular compensation in the central vestibular system - Review

Acta Oto-Laryngologica, Supplement

Volumn , Issue 539, 1998, Pages 19-27

  Kitahara, Tadashi ^a   Takeda, Noriaki ^a   Kiyama, Hiroshi ^b   Kubo, Takeshi ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

Flocculus; Fos; Labyrinthectomy; Medial vestibular nucleus; Nystagmus

Indexed keywords

4 AMINOBUTYRIC ACID; DIZOCILPINE; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE C; NITROGEN OXIDE;

CEREBELLUM FLOCCULUS; CONFERENCE PAPER; LABYRINTHECTOMY; NERVE PROJECTION; NYSTAGMUS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VESTIBULAR NUCLEUS; VESTIBULAR SYSTEM; ANIMAL; CEREBELLUM; CONVALESCENCE; INNER EAR; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; RAT; REVIEW;

ANIMALS; CEREBELLUM; EAR, INNER; GAMMA-AMINOBUTYRIC ACID; NITROGEN OXIDES; NYSTAGMUS, PATHOLOGIC; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RECOVERY OF FUNCTION; VESTIBULAR NUCLEI;

EID: 0032216818     PISSN: 03655237     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (59)

1. Precht W, Dieringer N. Neuronal events paralleling functional recovery (compensation) following peripheral vestibular lesions. In: Berthoz A, Melville-Jones G, eds. Adaptive mechanism in gaze control: facts and theories. Amsterdam: Elsevier, 1985: 251-68.
2. Smith PF, Curthoys IS. Mechanism of recovery following unilateral labyrinthectomy: a review. Brain Res Rev 1989; 14: 155-80.
3. Llinas R, Walton K. Vestibular compensation: a distributed property of the central nervous system. In: Wilson VJ, Asanuma H, eds. Integration in the nervous system. Tokyo: Igaku Shoin, 1979: 145-66.
4. Haddad GM, Friendlich AR, Robinson DA. Compensation of nystagmus after VIII the nerve lesions in vestibulo-cerebellectomized cats. Brain Res 1977; 135: 192-6.
5. Courjon JH, Flandrin M, Jeanneod M, Schmid R. The role of the flocculus in vestibular compensation after hemilabyrinthectomy. Brain Res 1982; 239: 251-7.
6. Darlington CL, Flohr H, Smith PF. Molecular mechanisms of brainstem plasticity. Mol Neurobiol 1991; 5: 355-68.
7. Kitahara T, Takeda N, Saika T, Kubo T, Kiyama H. Effects of MK801 on Fos expression in the rat brainstem after unilateral labyrinthectomy. Brain Res 1995; 700: 182-90.
8. Bullitt E. Induction of c-fos like protein within the lumbar spinal cord and thalamus of the rat following peripheral stimulation. Brain Res 1989; 493: 391-7.
9. Lee JH, Beitz AJ. The distribution of brain stem and spinal cord nuclei associated with different frequencies of electroacupuncture analgesia. Pain 1993; 52: 11-28.
10. Kitahara T, Saika T, Takeda N, Kubo T, Kiyama H. Changes in Fos and Jun expression after labyrinthectomy in the rat brainstem. Acta Otolaryngol 1995; Suppl 520: 401-4.
11. Smith PF, Curthoys IS. Neuronal activity in the ipsilateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy. Brain Res 1988; 444: 308-19.
12. Kitahara T, Takeda N, Kubo T, Kiyama H. Role of the flocculus in the development of vestibular compensation: immunohistochemical studies with retrograde tracing and flocculectomy using Fos expression as a marker in the rat brainstem. Neuroscience 1997; 76: 571-80.
13. Barmack NH, Baughman RW, Eckenstein FP, Shoujaku H. Secondary vestibular cholinergic projection to the cerebellum of rabbit and rat as revealed by choline acetyltransferase immunohistochemistry, retrograde and orthograde tracers. J Comp Neurol 1992; 317: 250-70.
14. McCabe BF, Ryu JH. Experiments of vestibular compensation. Laryngoscope 1969; 79: 1728-36.
15. Luneburg U, Flohr H. Possible role of NMDA receptors in vestibular compensation. In: Elsner N, Roth G, eds. Brain-perception cognition. Stuttgart: Thieme, 1990: 178.
16. Smith PF, Darlington CL. The NMDA antagonist MK801 and CPP disrupt compensation for unilateral labyrinthectomy in the guinea pig. Neurosci Lett 1988; 94: 309-13.
17. de Waele C, Vibert N, Baudrimont M, Vidai PP. NMDA receptors contribute to the resting discharge of vestibular neurons in the normal and hemilabyrinthectomized guinea pig. Exp Brain Res 1990; 81: 125-33.
18. Sekiguchi M, Okamoto K, Sakai Y. NMDA receptors on Purkinje cell dendrites in guinea pig cerebellar slices. Brain Res 1987; 437: 402-6.
19. Ottersen OP, Laake JH, Storm-Mathisen J. Demonstration of a releasable pool of glutamate in cerebellar mossy and parallel fibre terminals by means of light and electron microscopic immunocytochemistry. Arch Ital Biol 1990; 128: 111-25.
20. Petralia RS, Yokotani N, Wenthold RJ. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J Neurosci 1994; 14: 667-96.
21. Obata K, Takeda K. Release of GABA into the IVth ventricle induced by stimulation of the cat's cerebellum. J Neurochem 1969; 16: 1043-7.
22. Smith PF, Darlington CL. Neurochemical mechanism of recovery from peripheral vestibular lesions (vestibular compensation). Brain Res Rev 1991; 16: 117-33.
23. Precht W, Schwindt PC, Baker R. Removal of vestibular commissural inhibition by antagonists of GABA and glycine. Brain Res 1973; 62: 222-6.
24. Sekitani T, McCabe BF, Ryu JH. Drug effects on the medial vestibular nucleus. Arch Otolaryngol 1971; 93: 581-9.
25. McCabe BF, Sekitani T, Ryu JH. Drug effects on postlabyrinthectomy nystagmus. Arch Otolaryngol 1973; 98: 310-3.
26. Martin J, Gilchrist DPD, Smith PF, Darlington CL. Early diazepam treatment following unilateral labyrinthectomy does not impair vestibular compensation of spontaneous nystagmus in guinea pig. J Vestibular Res 1996; 6: 135-9.
27. Newman R, Winans SS. An experimental study of the ventral striatum of the golden hamster. I. Neuronal connections of the nucleus accumbens. J Comp Neurol 1980; 191: 167-92.
28. Smith PF, Curthoys IS. Neuronal activity in the contralateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy. Brain Res 1988; 444: 295-307.
29. Flugel G, Holm S, Flohr H. Physiological and clinical aspects. In: Moncada S, Feelisch M, Busse R, Higgs EA, eds. The Biology of Nitric Oxide. London: Portland Press, 1994: 381-7.
30. Kitahara T, Takeda N, Kubo T, Kiyama H. Role of the nitric oxide (NO)-mediated signalling in the rat bilateral floccular unipolar brush cells for vestibular compensation. Bruin Res 1997; 765: 1-6.
31. Mugnaini E, Floris A. The unipolar brush cell: a neglected neuron of the mammalian cerebellar cortex. J Comp Neurol 1994; 339: 174-80.
32. Rossi DJ, Alford S, Mugnaini E, Slater NT. Properties of transmission at a giant glutamatergic synapse in cerebellum: the mossy fibre-unipolar brush cell synapse. J Neurophysiol 1995; 74: 24-42.
33. Mugnaini E, Floris A, Wright-Goss M. Extraordinary synapses of the unipolar brush cell: an electron microscopic study in the rat cerebellum. Synapse 1994; 16: 284-311.
34. Shibuki K, Okada D. Endogenous nitric oxide release required for long-term synaptic depression in the cerebellum. Nature 1991; 349: 326-8.
35. Daniel H, Hemart N, Jaillard D, Crepel F. Long-term depression requires nitric oxide and guanosine 3':5' cyclic monophosphate production in rat cerebellar Purkinje cells. Eur J Neurosci 1993; 5: 1079-82.
36. Nagao S, Ito M. Subdural application of hemoglobin to the cerebellum blocks vestibulo-ocular reflex adaptation. Neuroreport 1991; 2: 193-6.
37. Li J, Smith SS, McEllgott JG. Cerebellar nitric oxide is necessary for vestibulo-ocular reflex adaptation, a sensorimotor model of learning. J Neurophysiol 1995; 74: 489-94.
38. Garthwaite J, Garthwaite G, Palmer RM, Moncada S. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur J Pharmacol 1988; 172: 413-6.
39. Bredt DS, Snyder SH. Nitric oxide mediates glutamate linked enhancement of cGMP levels in the cerebellum. Proc Natl Acad Sci USA 1989; 86: 9030-3.
40. Lin Y, Carpenter DO. Medial vestibular neurons are endogenous pacemakers whose discharge is modulated by neurotransmitters. Cell Mol Neurobiol 1993; 13: 601-13.
41. Lin Y, Carpenter DO. Direct excitatory opiate effects mediated by non-synaptic actions on rat medial vestibular neurons. Eur J Pharmacol 1994; 262: 99-106.
42. Saika T, Takeda N, Kiyama H, Tohyama M, Matsunaga T. Changes in preproenkephalin mRNA after unilateral and bilateral labyrinthectomy in the rat medial vestibular nucleus. Mol Brain Res 1993; 19: 237-40.
43. Sonnenberg JL, Rauscher III FJ, Morgan JI, Curran T. Regulation of Proenkephalin by Fos and Jun. Science 1989; 246: 1622-5.
44. Kitahara T, Takeda N, Kiyama H, Kubo T. An implication of protein phosphatase 2A-β in the rat flocculus for lesion-induced vestibularplaslicity. Acta Otolaryngol 1998; 118: 685-91.
45. Bear MF, Malenka RC. Synaptic plasticity: LTP and LTD. Curr Opin Neurobiol 1994; 4: 389-99.
46. Wang LY, Orser BA, Brautigan DL, MacDonald JF. Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatase 1 and 2A. Nature 1994; 369: 230-2.
47. Roche KW, Tingley WG, Hunganir RL. Glutamate receptor phosphorylation and synaptic plasticity. Curr Opin Neurobiol 1994; 4: 383-8.
48. Goto MM, Romero GG, Balaban CD. Transient changes in flocculonodular lobe protein kinase C expression during vestibular compensation. J Neurosci 1997; 17: 4367-81.
49. Barmack NH, Baughman RW, Eckenstein FP, Shoujaku H. Influence of unilateral labyrinthectomy on expression of protein kinase C in a cerebellar-vestibular pathway in rat. Soc Neurosci Abstr 1995; 21: 467.4.
50. Kitahara T, Takeda N, Uno A, Kubo T, Kiyama H. Unilateral labyrinthectomy downregulates glutamate receptor 52 expression in the rat vestibulocercbellum. Mol Brain Res (In press).
51. Araki K, Meguro H, Kushiya E, Takayama C, Inoue Y, Mishina M. Selective expression of the glutamate receptor channel δ2 subunit in cercbellar Purkinje cells. Biochem Biophys Res Commun 1993; 197: 1267-76.
52. Lomeli H, Sprengel R, Laurie DJ, Kohr G, Herb A, Seeburg PH, et al. The rat δ1 and δ2 subunits extend the excitatory amino acid receptor family. FEBS Lett 1993; 315: 318-22.
53. Mayat E, Petralia RS, Wang YX, Wenthold RJ. Immunoprecipitation, immunoblotting, and immunocytochemistry studies suggest that glutamate receptor δ subunits form novel postsynaptic receptor complexes. J Neurosci 1995; 15: 2533-46.
54. Yamazaki M, Araki K, Shibata A, Mishina M. Molecular cloning of cDNA encoding a novel member of the mouse glutamate receptor channel family. Biochem Biophys Res Commun 1992; 183: 886-92.
55. Dicringer N, Precht W. Mechanism of compensation for vestibular deficits in the frog. II. Modifications of the inhibitory pathways. Exp Brain Res 1979; 36: 329-41.
56. Flohr H, Bienhold H, Abeln W, Macskovics I. Concepts of vestibular compensation. In: Flohr H, Precht W, eds. Lesion-induced neuronal plasticity in sensorimotor systems. Amsterdam: Springer, 1981: 153-72.
57. Smith PF, Darlington CL, Curthoys TS. The effect of visual deprivation on vestibular compensation in the guinea pig. Brain Res 1986; 364: 195-8.
58. de Waele C, Graf W, Josset P, Vidal PP. A radiological analysis of the postural syndromes following hemilabyrinthectomy and selective canal and otolith lesions in the guinea pig. Exp Brain Res 1989; 77: 166-82.
59. Galiana HL, Flohr H, Melville-Jones G. A reevaluation of intervestibular nuclear coupling: its role in vestibular compensation. J Neurophysiol 1984; 51: 242-59.