Fetal development in alloxan-treated rats

Reproductive Toxicology

Volumn 12, Issue 6, 1998, Pages 659-665

  Palomar Morales, Martín ^a   Baiza, Luis A ^a   Verdín Terán, Leticia ^a   Román Ramos, Rubén ^a   Altamirano Lozano, Mario ^a   Méndez, José D ^a  

^a NONE

Author keywords

Alloxan; Diabetes; Embryotoxicity; Fetal development

Indexed keywords

ALLOXAN;

ANIMAL; ANIMAL EXPERIMENT; ARTICLE; DIABETES MELLITUS; DOSE RESPONSE; DRUG EFFECT; EMBRYO DEATH; EMBRYO RESORPTION; EMBRYOTOXICITY; EXPERIMENTAL DIABETES MELLITUS; FEMALE; FETOMATERNAL TRANSFUSION; FETUS; FETUS DEVELOPMENT; HYPERGLYCEMIA; IATROGENIC DISEASE; MALE; NONHUMAN; PATHOPHYSIOLOGY; PREGNANCY; RAT;

ALLOXAN; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO LOSS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; HYPERGLYCEMIA; MALE; MATERNAL-FETAL EXCHANGE; PREGNANCY; RATS;

EID: 0032216225     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(98)00043-4     Document Type: Article

References (28)

1. Buchanan T.A., Kitzmiller J.L. Metabolic interactions of diabetes and pregnancy. Annu Rev Med. 45:1994;245-269.
2. Felig P, Coustan D. Diabetes sacarina. In: Burrow GN, Ferris TF, eds. Complicaciones médicas durante el embarazo. 2a. Buenos Aires: Panamericana. 1989;55-81.
3. New D.A.T. Whole embryo culture and the study of mammalian embryos during organogenesis. Biol Rev. 53:1978;81-122.
4. Eriksson U.F., Borg L.A.H., Forsberg H., Styrud J. Diabetic embryopathy. Diabetes. 40:1991;94-98.
5. Kalter H. Reproductive toxicology in animals with induced and spontaneous diabetes. Reprod Toxicol. 10:1996;417-438.
6. Beaudoin A.R. Embryology and teratology. Baker H.J., Lindsey J.R., Weisbruth S.H. The laboratory rat. Vol. II:1980;75-101 Academic Press, San Diego.
7. Gilbert S.F. Developmental biology. 2a. 1988;153-195 Sinauer, Sunderland.
8. Barrow M.V., Taylor W.J. A rapid method for detecting malformations in rat fetuses. J Morphol. 127:1969;291-306.
9. Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann Clin Biochem. 6:1969;24.
10. Frings C.S., Fendley T.W., Dunn R.T., Queen C.A. Improved determination of total serum lipids by the sulpho-phospho-vainillin reaction. Clin Chem. 18:1972;673.
11. Wahlefeld AW. In. Bergmeyer HU, Methoden der enzymatischen analyse. 3a. Ed. Tomo II. Weinheim: Verlag-Chemie, 1979;1878.
12. Davis M.E., Fugo N.W., Lawrence K.G. Effect of alloxan diabetes on reproduction in the rat. Proc Soc Exp Biol Med. 66:1947;638-641.
13. Kim J.N., Runge W., Welles L.J., Lazarow A. Effects of experimental diabetes on the offspring of the rat: fetal growth, birth weight, gestation period, and fetal mortality. Diabetes. 9:1969;396-404.
14. Sinden J.A., Longwell B.B. Effect of alloxan diabetes on fertility and gestation in the rat. Proc Soc Exp Biol Med. 70:1949;607-610.
15. Lawrence A.M., Contopoulos A.N. Reproductive performance in the alloxan diabetic female rat. Acta Endocrinol. 33:1960;175-184.
16. Lazarow A., Kim J.N., Wells L.J. Birth weight and fetal mortality in pregnant subdiabetic rats. Diabetes. 9:1960;114-117.
17. Foglia V.G., Borghelli D.D.S., Chieri R.A., Fernández-Collazo E.L., Spindler I., Wesely O. Sexual disturbances in the diabetic rat. Diabetes. 12:1963;231-237.
18. Levi J.E., Weinberg T. Pregnancy in alloxan diabetic rats. Proc Soc Exp Biol Med. 72:1949;658-662.
19. Howland B.E., Zebrowski E.J. Gonadotropin levels in sera and pituitary glands of female rats treated with alloxan. Life Sci. 14:1974;289-296.
20. Angerwall L. Alloxan diabetes and pregnancy in the rat. Acta Endocrinol. 39:(Suppl 44):1959;1.
21. Horii K.-I., Watanabe G.-I., Ingalls T.H. Experimental diabetes in pregnant mice: prevention of congenital malformations in offspring by insulin. Diabetes. 15:1966;194-204.
22. Takano K., Nishimura H. Congenital malformations induced by alloxan diabetes in mice and rats. Anat Rec. 158:1966;303-312.
23. Watanabe G.-I., Ingalls T.H. Congenital malformations in the offspring of alloxan-diabetic mice. Diabetes. 12:1963;66-72.
24. Deuchar E.M. Embryonic malformations in rats resulting from maternal diabetes: preliminary observations. J Embryol Exp Morphol. 41:1977;93-99.
25. Ellison A.C., Maren T.H. The effects of metabolic alterations on teratogenesis. Johns Hopkins Med J. 130:1972;87-94.
26. Wilson J.G. Current status of teratology: general principles and mechanisms derived from animal studies. Wilson J.G., Fraser F.C. Handbook of teratology: general principles and etiology. Vol. I:1977;46 Plenum Press, New York.
27. Responsible use of animals for research. Diabetes Care. 13:(Suppl):1990;38.
28. Méndez J.D., Ramos H.G. Modelos experimentales. Islas A.S., Lifshitz A. Diabetes mellitus. 1993;303 Interamericana, México, DF.