Dephosphorylation, proteolysis, and reduced activity of poly(A) polymerase associated with U937 cell apoptosis

Experimental Cell Research

Volumn 244, Issue 2, 1998, Pages 433-440

  Atabasides, H ^a   Tsiapalis, C M ^b   Havredaki, M ^a  

^a INSTITUTE OF NANOSCIENCE AND NANOTECHNOLOGY   (Greece)

^b SAINT SAVVAS HOSPITAL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; POLYNUCLEOTIDE ADENYLYLTRANSFERASE;

APOPTOSIS; ARTICLE; DEPHOSPHORYLATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

EID: 0032213694     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4231     Document Type: Article

References (45)

1. Ameisen J. C. Programmed cell death (apoptosis) and cell survival regulation: Relevance to AIDS and cancer. AIDS. 8:1994;1197-1213.
2. Kroemer G., Petit P., Zamzami N., Vayssiere J-L., Mignotte B. The biochemistry of programmed cell death. FASEB J. 9:1995;1277-1287.
3. Osborne B. A., Schwartz L. M. Essential genes that regulate apoptosis. Trends Cell Biol. 4:1994;394-399.
4. Mondino A., Jenkins M. K. Accumulation of sequence-specific RNA-binding proteins in the cytosol of activated T cells undergoing RNA degradation and apoptosis. J. Biol. Chem. 270:1995;26593-26601.
5. Gjertsen B. T., Døskeland S. O. Protein phosphorylation in apoptosis. Biochim. Biophys. Acta. 1269:1995;187-199.
6. Pongracz J., Tuffley W., Johnson G. D., Deacon E. M., Burnett D., Stockley R. A., Lord J. M. Changes in protein kinase C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells. Exp. Cell Res. 218:1995;430-438.
7. Zhivotovsky B., Burgess D. H., Vanags D. M., Orrenius S. Involvement of cellular proteolytic machinery in apoptosis. Biochem. Biophys. Res. Commun. 230:1997;481-488.
8. Baxter G. D., Lavin M. F. Specific protein dephosphorylation in apoptosis induced by ionizing radiation and heat shock in human lymphoid tumor lines. J. Immunol. 148:1992;1949-1954.
9. Morana S. J., Wolf C. M., Li J., Reynolds J. E., Brown M. K., Eastman A. The involvement of protein phosphatases in the activation of ICE/CED-3 protease, intracellular acidification, DNA digestion, and apoptosis. J. Biol. Chem. 271:1996;18263-18271.
10. Kaufmann S. H., Desnoyers S., Ottaviano Y., Davidson N. E., Poirier G. G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res. 53:1993;3976-3985.
11. Zhivotovsky B., Gahm A., Orrenius S. Two different proteases are involved in the proteolysis of lamin during apoptosis. Biochem. Biophys. Res. Commun. 233:1997;96-101.
12. Casciola-Rosen L. A., Miller K. D., Anhalt G. J., Rosen A. Specific cleavage of the 70 kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. J. Biol. Chem. 269:1994;30757-30760.
13. Gunderson S. I., Beyer K., Martin G., Keller W., Boelens W. C., Mattaj I. W. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase. Cell. 76:1994;531-541.
14. An B., Dou Q. P. Cleavage of retinoblastoma protein during apoptosis: An interleukin 1b-converting enzyme-like protease as candidate. Cancer Res. 56:1996;438-442.
15. Wahle E., Kuhn U. The mechanism of 3′ cleavage and polyadenylation of eukaryotic pre-mRNA. Progr. Nucleic Acid Res. Mol. Biol. 57:1997;41-71.
16. Colgan D. F., Manley J. L. Mechanism and regulation of mRNA polyadenylation. Genes Dev. 11:1997;2755-2766.
17. Wahle E. 3′-end cleavage and polyadenylation of mRNA precursor. Biochim. Biophys. Acta. 1261:1995;183-194.
18. Ballantyne S., Bilger A., Aström J., Virtanen A., Wickens M. Poly(A) polymerases in the nucleus and cytoplasm of frog oocytes: Dynamic changes during oocyte maturation and cell development. RNA. 1:1995;64-78.
19. Colgan D. F., Murthy K. G. K., Prives C., Manley J. L. Cell-cycle related regulation of poly(A) polymerase by phosphorylation. Nature. 384:1996;282-285.
20. Thuresson A-C., Aström J., Aström A., Grönvik K-O., Virtanen A. Multiple forms of poly(A) polymerases in human cells. Proc. Natl. Acad. Sci. USA. 91:1994;979-983.
21. Zhao W., Manley J. L. Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms. Mol. Cell. Biol. 16:1996;2378-2386.
22. Kyriakopoulou C., Tsiapalis C. M., Havredaki M. Biochemical and immulological identification and enrichment of poly(A) polymerase from human thymus. Mol. Cell. Biochem. 154:1996;9-16.
23. Wittman T., Wahle E. Purification and characterization of full-length mammalian poly(A) polymerase. Biochim. Biophys. Acta. 1350:1997;293-305.
24. Raabe T., Bollum F. J., Manley J. L. Primary structure and expression of bovine poly(A) polymerase. Nature. 353:1991;229-234.
25. Martin G., Keller W. Mutational analysis of mammalian poly(A) polymerase identifies a region for primer binding and a catalytic domain, homologous to the family X polymerases, and to other nucleotidyltransferases. EMBO J. 15:1996;2593-2603.
26. Lowry O. H., Rosenbrough N. J., Farr A. L., Randall R. J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
27. Tsiapalis C. M., Dorson J. W., Bollum F. J. Purification of the terminal riboadenylate transferase from calf thymus gland. J. Biol. Chem. 250:1975;4486-4496.
28. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
29. Burnette N. W. "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112:1981;195-203.
30. Trangas T., Courtis N., Pangalis G. A., Cosmides H. V., Ioannidis C., Papamichail M., Tsiapalis C. M. Polyadenylic acid polymarase activity in normal and leukemic human leukocytes. Cancer Res. 44:1984;3691-3697.
31. Lazebnik Y. A., Cole S., Cooke C. A., Nelson W. G., Earnshaw W. C. Nuclear events of apoptosisin vitro. J. Cell Biol. 123:1993;7-22.
32. 2+. Methods Cell Biol. 46:1995;41-55.
33. McGahon A., Bissonnette R., Schmitt M., Cotter K. M., Green D. R., Cotter T. G. BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood. 83:1994;1179-1187.
34. Ghibelli L., Nosseri C., Oliverio S., Piacentini M., Autuori F. Cycloheximide can rescue heat-shocked L cells from death by blocking stress-induced apoptosis. Exp. Cell Res. 201:1992;436-443.
35. Edmonds, M. 1982, Poly(A) adding enzymes, The Enzymes, XV, 217, 244.
36. Tsiapalis C. M. Regulation of mRNA polyadenylation-deadenylation. Mol. Biol. Rep. 12:1987;291-298.
37. Jacob S. T., Terns M. P., Maguire K. A. Polyadenylate polymerase from normal and cancer cells and their potential role in messenger RNA processing: A review. Cancer Res. 49:1989;2827-2833.
38. Kazazoglou T., Tsiapalis C. M., Havredaki M. Polyadenylate polymerase activity in stationary and growing cell cultures. Exp. Cell Biol. 55:1987;164-172.
39. Oberhammer F., Wilson J. W., Dive C., Morris I. D., Hickman J. A., Wakeling A. E., Walker P. R., Sikorska M. Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12:1993;3679-3684.
40. 34cdc2. EMBO J. 17:1998;1053-1062.
41. Gunderson S. I., Vagner S., Polycarpon-Scharz M., Mattaj I. W. Involvement of the carboxyl terminus of vertebrate poly(A) polymerase in U1A autoregulation and in the coupling of splicing and polyadenylation. Genes Dev. 11:1997;761-773.
42. Martin S. J., Lennon S. V., Bonham A. M., Cotter T. G. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. J. Immunol. 145:1990;1859-1867.
43. Chow S. C., Peters I., Orrenius S. Reevaluation of the role of de novo protein synthesis in rat thymocyte apoptosis. Exp. Cell Res. 216:1995;149-159.
44. Patel T., Gores G. J., Kaufmann S. H. The role of proteases during apoptosis. FASEB J. 10:1996;587-597.
45. Idriss H., Kumar A., Casas-Finet J. R., Guo H., Damuni Z., Wilson S.H. Regulation ofin vitro. Biochemistry. 33:1994;11382-11390.