Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms

Molecular and Cellular Biology

Volumn 16, Issue 5, 1996, Pages 2378-2386

  Zhao, Wenqing ^a   Manley, James L ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; POLYCLONAL ANTIBODY; POLYNUCLEOTIDE ADENYLYLTRANSFERASE;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; DNA LIBRARY; ENZYME ACTIVITY; GENE EXPRESSION; GENE STRUCTURE; GENOME; IMMUNOBLOTTING; LIVER; MOUSE; NONHUMAN; POLYADENYLATION; PRIORITY JOURNAL; PSEUDOGENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING;

ALCES ALCES; ANIMALIA; ANURA; BOVINAE; UNIDENTIFIED BACULOVIRUS;

EID: 0029978731     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.5.2378     Document Type: Article

References (52)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1995. Current protocols in molecular biology. John Wiley & Sons, Inc., New York
2. Ballantyne, S., A. Bilger, J. Astrom, A. Virtanen, and M. Wickens. 1995 Poly(A) polymerases in the nucleus and cytoplasm of frog oocytes: dynamic changes during oocyte maturation and early development RNA 1:64-78.
3. Bienroth, S., E. Wahle, C. Satler-Crazzolara, and W. Keller. 1991. Purification of the cleavage and polyadenylation factor involved in 3′ processing of mRNA precursors. J. Biol. Chem. 266:19768-19776.
4. Boelens, W. C., E. Jansen, W. Venrooij, R. Stripecke, I. Mattaj, and S. I. Gunderson. 1993. The human U1 snRNP-specific U1A protein inhibits polyadenylation of its own pre-mRNA Cell 72:881-892
5. Brosius, J. 1991. Retroposons - seeds of evolution Science 251:753.
6. Chomczynski, P., and N. Sacchi. 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 162:156-159.
7. Christofori, G., and W. Keller. 1988. 3′ cleavage and polyadenylation of messenger RNA precursors in vitro requires a poly(A) polymerase, a cleavage factor, and a small nuclear ribonucleoprotein particle. Cell 54:875-889.
8. Christofori, G., and W. Keller. 1989. Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro. Mol. Cell Biol. 9:193-203.
9. Edmonds, M., and R. J. Abrams. 1960. Polynucleotide biosynthesis: formation of a sequence of adenylate units from adenosine triphosphate by an enzyme from thymus nuclei. J. Biol. Chem. 235:1142-1149.
10. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6-13.
11. cdc2/cyclin B phosphorylation. Submitted for publication.
12. Fox, C. A., M. D. Sheets, E. Wahle, and M. Wickens. 1992. Polyadenylation of maternal mRNA during oocyte maturation: poly(A) addition in vitro requires a regulated RNA binding activity and a poly(A) polymerase. EMBO J. 11:5021-5032.
13. Fu, X.-Y., and J. L. Manley. 1987. Factors influencing alternative splicing site utilization in vivo. Mol. Cell. Biol. 7:738-748.
14. Gebauer, F., and J. D. Richter. 1995. Cloning and characterization of a Xenopus poly(A) polymerase. Mol. Cell. Biol. 15:1422-1430.
15. Gilmartin, G. M., and J. R. Nevins. 1989 An ordered pathway of assembly of components required for polyadenylation site recognition and processing. Genes Dev. 3:2180-2189.
16. Gunderson, S. I., K. Beyerm, G. Martin, W. Keller, W. Boelens, and I. W. Mattaj. 1994. The human U1A snRNP protein regulates polyadenylation via a direct interaction with poly(A) polymerase Cell 76:531-541.
17. Gyllensten, U. B., and H. A. Erlich. 1988. Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus. Proc Natl Acad. Sci. USA 85:7652-7656.
18. Harlow, E., and D. Lane. 1988. Antibodies, a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
19. Keller, W. 1995. No end yet to messenger RNA 3′ processing. Cell 81:829-832.
20. MacDonald, C. C., J. Wilusz, and T. Shenk. 1994. The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol. Cell. Biol. 14:6647-6654.
21. Manley, J. L. 1995. A complex protein assembly catalyzes polyadenylation of mRNA precursors. Curr. Opin. Genet. Dev. 5:222-228.
22. McGrew, L. L., E. Dworkin-Rastle, M. B. Dworkin, and J. D. Richter. 1989. Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element. Genes Dev. 3:803-815.
23. Miller, D. W., P. Safer, and L. K. Miller. 1986. An insect baculovirus host-vector system for high-level expression of foreign genes. Genet. Eng. 8:277-298.
24. Minvielle-Sebastia, L., P. J. Preker, and W. Keller. 1994. RNA14 and RNA15 proteins as components of a yeast pre-mRNA 3′-end processing factor. Science 266:1702-1705.
25. Minvielle-Sebastia, L., B. Winsor, N. Bonneaud, and F. Lacroule. 1991. Mutations in the yeast RNA14 and RNA15 genes result in an abnormal mRNA decay rate; sequence analysis reveals an RNA-binding domain in the RNA15 protein. Mol. Cell. Biol. 11:3075-3087.
26. Mitchelson, A., M. Simonelig, C. Williams, and K. O'Hare. 1993. Homology with Saccharomyces cerevisiae RNA14 suggests that phenotypic suppression in Drasophila melanogaster by suppressor of forked occurs at the level of RNA stability. Genes Dev. 7:241-249.
27. Murthy, K. G. K., and J. L. Manley. 1992. Characterization of the multisubunit cleavage polyadenylation specificity factor from calf thymus. J. Biol. Chem. 267:14804-14811.
28. Murthy, K. G. K., and J. L. Manley. 1995. The 160kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3′ end formation. Genes Dev. 9:2672-2683.
29. Peterson, M. L. 1994 RNA processing and the expression of immunoglobulin genes, p. 321-342. In E. C. Snow (ed.), Handbook of B and T lymphocytes. Academic Press, San Diego, Calif.
30. Peterson, M. L. 1994. Regulated immunoglobulin (Ig) RNA processing does not require specific cis-acting sequences: non-Ig RNA can be alternatively processed in B cells and plasma cells. Mol. Cell Biol. 14:7891-7898.
31. Raabe, T., F. J. Bollum, and J. L. Manley. 1991 Primary structure and expression of bovine poly(A) polymerase Nature (London) 353:229-234.
32. Raabe, T., K. Murthy, and J. L. Manley. 1994. Poly(A) polymerase contains multiple functional domains Mol. Cell. Biol. 14:2945-2957.
33. Ryner, L. C., Y. Takagaki, and J. L. Manley. 1989. Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3′-end formation. Mol. Cell. Biol. 9:4229-4238
34. Salles, F. J., M. E. Lieberfaib, C. Wreden, J. P. Gergen, and S. Strickland. 1994. Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs. Science 266:1996-1999.
35. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y
36. Sheets, M. D., C. A. Fox, T. Hunt, G. V. Woude, and M. Wickens. 1994. The 3′-untranslated region of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation. Genes Dev. 8:926-938
37. Sheets, M. D., M. Wu, and M. Wickens. 1995. Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. Nature (London) 374:511-516.
38. Takagaki, Y., C. C. MacDonald, T. Shenk, and J. L. Manley. 1992. The human 64-kD polyadenylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proc. Natl Acad. Sci. USA 89:1403-1407.
39. Takagaki, Y., and J. L. Manley. 1994. A polyadenylation factor subunit is the human homologue of the Drosophila suppressor of forked protein. Nature (London) 372:471-474.
40. Takagaki, Y., and J. L. Manley. Unpublished results.
41. Takagaki, Y., J. L. Manley, C. C. MacDonald, J. Wilusz, and T. Shenk. 1990 A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev. 4:2112-2120.
42. Takagaki, Y., L. C. Ryner, and J. L. Manley. 1988. Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation. Cell 52:731-742.
43. Takagaki, Y., L. C. Ryner, and J. L. Manley. 1989. Four factors are required for 3′-end cleavage of pre-mRNA Genes Dev. 3:1711-1724.
44. Thuresson, A., J. Astrom, A. Astrom, K. Gronvik, and A. Virtanen. 1994. Multiple forms of poly(A) polymerases in human cells. Proc. Natl Acad Sci USA 91:979-983.
45. Thuresson, A., and A. Virtanen. Personal communication.
46. Vanin, E. F. 1985 Processed pseudogene: characteristics and evolution. Annu. Rev. Genet. 19:253-272
47. Wahle, E. 1991. Purification and characterization of a mammalian polyadenylate polymerase involved in the 3′ end processing of messenger RNA precursors. J. Biol. Chem. 266:3131-3139.
48. Wahle, E., G. Martin, E. Schilts, and W. Keller. 1991. Isolation and expression of cDNA clones encoding mammalian poly(A) polymerase. EMBO J. 10:4251-4257.
49. Weiner, A. M. 1986. Nonviral retroposons: genes, pseudogenes, and transposable elements generated by the reverse flow of genetic information. Annu. Rev Biochem. 55:631-661.
50. Wickens, M. 1992. Forward, backward, how much, when: mechanisms of poly(A) addition and removal and their role in early development Semin. Dev. Biol. 3:399-412.
51. Williams, C., and K. O'Hare. Personal communication.
52. Zachar, Z., T. Chou, and P. M. Bingham. 1987. Evidence that a regulatory gene autoregulates splicing of its transcript. EMBO J. 6:4105-4111