Dietary fiber stimulates the extra-renal route of nitrogen excretion in partially nephrectomized rats

Journal of Nutritional Biochemistry

Volumn 9, Issue 11, 1998, Pages 613-620

  Younes, Hassan ^a   Garleb, Keith A ^b   Behr, Stephen R ^b   Demigné, Christian ^a   Rémésy, Christian ^a  

^a CEMAGREF   (France)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Dietary fiber; Dietary protein; Nitrogen excretion; Plasma urea; Rats; Renal failure

Indexed keywords

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIET; DIETARY FIBER; FECES; KIDNEY FAILURE; MALE; NEPHRECTOMY; NITROGEN URINE LEVEL; NONHUMAN; RAT;

EID: 0032212877     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-2863(98)00062-X     Document Type: Article

References (34)

1. Bras G., Ross M.H. Kidney disease and nutrition in the rat. Toxicol. Appl. Pharmacol. 6:1964;247-262.
2. Brenner B.M., Meyer T.W., Hostetter T.H. Dietary protein intake and the progressive nature of kidney disease. N. Engl. J. Med. 307:1982;652-659.
3. Klahr S., Levey A.S., Beck G.J., Caggiula A.W., Hunsicker L., Kusek J.W., Striker G. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of diet in renal disease study group. N. Engl. J. Med. 330:1994;877-884.
4. Franklin S.S., Gordon A., Kleeman C.R., Maxwell M.H. Use of a balanced low-protein diet in chronic renal failure. JAMA. 202:1967;141-148.
5. Johnson W.J., Hagge W.W., Wagoner R.D., Dinapoli R.P., Rosevear J.W. Effects of urea loading in patients with far-advanced renal failure. Mayo Clin. Proc. 47:1972;21-29.
6. Mitch W.E. Dietary protein restriction in chronic renal failure: Nutritional efficacy, compliance and progression of renal insufficiency. J. Am. Soc. Nephrol. 2:1991;823-831.
7. Maschio G., Oldrizzi L., Tessitore N., D'Angelo A., Valvo E., Lupo A., Loschiavo C., Fabris A., Gammaro L., Rugiu C. Early dietary protein and phosphorus restriction is effective in delaying progression of chronic renal failure. Kidney Int. 24:(suppl 16):1983;S273-S277.
8. Walker J.D., Bending J.J., Dodds R.A., Mattock M.B., Murrells T.J., Keen H., Viberti G.C. Restriction of dietary protein and progression of renal failure in diabetic nephropathy. Lancet. 2:1989;1411-1415.
9. Zeller K., Whittaker E., Sullivan L., Raskin P., Jacobson H.R. Effect of restricting dietary protein on the progression of renal failure in patients with insulin-dependent diabetes mellitus. N. Engl. J. Med. 324:1991;78-84.
10. Klahr S. Prevention of progression of nephropathy. Nephrol. Dial. Transplant. 12:(suppl 2):1997;S63-S66.
11. Bliss D.Z., Stein T.P., Schleifer C.R., Settle R.G. Supplementation with gum arabic fiber increases fecal nitrogen excretion and lowers serum urea nitrogen concentration in chronic renal failure patients consuming a low-protein diet. Am. J. Clin. Nutr. 63:1996;392-398.
12. Younes H., Garleb K., Behr S., Rémésy C., Demigné C. Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the cecum. J. Nutr. 125:1995;1010-1016.
13. Younes H., Rémésy C., Behr S., Demigné C. Fermentable carbohydrate exerts a urea-lowering effect in normal and nephrectomized rats. Am. J. Physiol. 272:1997;G515-G521.
14. Weber F.L., Minco D., Fresard K.M., Banwell J.G. Effects of vegetable diets on nitrogen metabolism in cirrhotic subjects. Gastroenterology. 89:1985;538-544.
15. Parillo M., Riccardi G., Pacioni D., Iovine C., Contaldo F., Isernia C., De Marco F., Perrotti N., Rivellese A. Metabolic consequences of feeding a high-carbohydrate, high-fiber diet to diabetic patients with chronic kidney faillure. Am. J. Clin. Nutr. 48:1988;255-259.
16. Mortensen P.B. Effect of oral-administered lactulose on colonic nitrogen metabolism and excretion. Hepatology. 16:1992;1350-1356.
17. Stephen A.M., Dahl W.J., Sieber G.M., Blaricom J.A.V., Morgan D.R. Effect of green lentils on colonic function, nitrogen balance, and serum lipids in healthy human subjects. Am. J. Clin. Nutr. 62:1995;1261-1267.
18. Demigné C., Rémésy C. Stimulation of absorption of volatile fatty acids and minerals in the cecum of rats adapted to a very high fiber diet. J. Nutr. 115:1985;53-60.
19. Younes H., Demigné C., Behr S.R., Garleb K.A., Rémésy C.A. Blend of dietary fibers increases urea disposal in the large intestine and lowers urinary nitrogen excretion in rats fed a low protein diet. J. Nutr. Biochem. 7:1996;474-480.
20. Kleinknecht D., Laouari D., Burtin M. Uremic rat model: Experience with young rats. Contr. Nephrol. 60:1988;27-38.
21. Tulung B., Rémésy C., Demigné C. Specific effects of guar gum or arabic gum on adaptation of cecal digestion to high fiber diets in the rat. J. Nutr. 117:1987;1556-1561.
22. Demigné C., Rémésy C., Rayssiguier Y. Effect of fermentable carbohydrates on volatile fatty acids, ammonia and mineral absorption in the rat cecum. Reprod. Nutr. Develop. 20:1980;1351-1359.
23. Gutmann I., Bergmeyer H.U. Determination of urea with glutamate dehydrogenase as indicator enzyme. Bermeyer H.U. Methods of Enzymatic Analysis. vol. 3:1974;1794-1797 Academic Press, New York, NY, USA.
24. Kun E., Kearney E.B. Ammonia. Bermeyer H.U. Methods of Enzymatic Analysis. vol. 3:1974;1802-1806 Academic Press, New York, NY, USA.
25. Bartels H., Bohmer M., Heierli C. Serum kreatininbestimmung ohne enteiweissen. Clin. Chim. Acta. 37:1972;193-197.
26. Langran M., Moran B.J., Murphy J.L., Jackson A.A. Adaptation to a diet low in protein: Effect of complex carbohydrate upon urea kinetics in normal man. Clin. Sci. 82:1992;191-198.
27. Brown C.L., Hill M.J., Richards P. Bacterial ureases in uremic men. Lancet. 21:1971;406-408.
28. Tetens I., Livesey G., Eggum B.O. Effects of type and level of dietary fiber supplements on nitrogen retention and excretion patterns. Br. J. Nutr. 75:1996;461-469.
29. Stephen A.M., Cummings J.H. The microbial contribution to human faecal mass. J. Med. Microbiol. 13:1980;45-56.
30. Stephen A.M. Dietary fiber and colonic nitrogen metabolism. Scand. J. Gastroenterol. 22:(suppl 129):1987;S110-S115.
31. Viallard V. Endogenous urea as a nitrogen source for microorganisms of the rabbit digestive tract. Ann. Nutr. Metab. 28:1984;151-155.
32. Metges C.C., El-khoury A.E., Petzeke K.J. The quantitative contribution of microbial lysine to lysine flux in healthy male subjects. FASEB J. 867:1997;A149.
33. Bödeker D., Shen Y., Kemkowski J., Höller H. Influence of short-chain fatty acids on ammonia absorption across the rumen wall in sheep. Experimental Physiology. 77:1992;369-376.
34. Rémésy C., Moundras C., Morand C., Demigné C. Glutamine or glutamate release by the liver constitutes a major mechanism for nitrogen salvage. Am. J. Physiol. 272:1997;G257-G264.