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Volumn 55, Issue 21 SUPPL., 1998, Pages

Promising agents for treating Alzheimer's disease

Author keywords

Alzheimer's disease; Anti inflammatory agents; Antioxidants; Clinical studies; Combined therapy; Drug comparisons; Drugs; EGb 761; Estrogens; Ginkgo biloba; Investigational; Mechanism of action; Selegiline; Toxicity; Vitamin E; Vitamins

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ASCORBIC ACID; CHOLINESTERASE INHIBITOR; DONEPEZIL; ESTROGEN; GALANTAMINE; GINKGO BILOBA EXTRACT; HEPTYLSTIGMINE TARTRATE; METRIFONATE; MONOAMINE OXIDASE INHIBITOR; NERVE GROWTH FACTOR; NONSTEROID ANTIINFLAMMATORY AGENT; PHYSOSTIGMINE; RISPERIDONE; RIVASTIGMINE; SELEGILINE; SEROTONIN UPTAKE INHIBITOR; TACRINE; TRAZODONE; UNCLASSIFIED DRUG; XANOMELINE;

EID: 0032211787     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/55.suppl_2.s11     Document Type: Conference Paper
Times cited : (16)

References (33)
  • 1
    • 0029347141 scopus 로고
    • Adjunctive therapy in patients with Alzheimer's disease: A practical approach
    • Corey-Bloom J, Galasko D. Adjunctive therapy in patients with Alzheimer's disease: a practical approach. Drugs Aging. 1995; 7:79-87.
    • (1995) Drugs Aging , vol.7 , pp. 79-87
    • Corey-Bloom, J.1    Galasko, D.2
  • 2
    • 0029838038 scopus 로고    scopus 로고
    • Neuropsychiatric aspects of Alzheimer's disease: The cholinergic hypothesis revisited
    • Cummings JL, Kaufer D. Neuropsychiatric aspects of Alzheimer's disease: the cholinergic hypothesis revisited. Neurology. 1996; 47:876-83.
    • (1996) Neurology , vol.47 , pp. 876-883
    • Cummings, J.L.1    Kaufer, D.2
  • 4
    • 0019410162 scopus 로고
    • Alzheimer's disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis
    • Whitehouse PJ, Price DL, Clark AW et al. Alzheimer's disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann Neurol. 1981; 10:122-6.
    • (1981) Ann Neurol. , vol.10 , pp. 122-126
    • Whitehouse, P.J.1    Price, D.L.2    Clark, A.W.3
  • 5
    • 0020072221 scopus 로고
    • Alzheimer's disease and senile dementia: Loss of neurons in the basal forebrain
    • Whitehouse PJ, Price DL, Struble RG et al. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science. 1982; 215:1237-9.
    • (1982) Science , vol.215 , pp. 1237-1239
    • Whitehouse, P.J.1    Price, D.L.2    Struble, R.G.3
  • 6
    • 0018078940 scopus 로고
    • Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia
    • Perry EK, Tomlinson BE, Blessed G et al. Correlation of cholinergic abnormalities with senile plaques and mental test scores in senile dementia. Br Med J. 1978; 2:1457-9.
    • (1978) Br Med J. , vol.2 , pp. 1457-1459
    • Perry, E.K.1    Tomlinson, B.E.2    Blessed, G.3
  • 7
    • 0031842293 scopus 로고    scopus 로고
    • Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease
    • Morris JC, Cyrus PA, Orazem J et al. Metrifonate benefits cognitive, behavioral, and global function in patients with Alzheimer's disease. Neurology. 1998; 50:1222-30.
    • (1998) Neurology , vol.50 , pp. 1222-1230
    • Morris, J.C.1    Cyrus, P.A.2    Orazem, J.3
  • 8
    • 0032213644 scopus 로고    scopus 로고
    • Pharmacology and clinical efficacy of cholinesterase inhibitors
    • Jann MW. Pharmacology and clinical efficacy of cholinesterase inhibitors. Am J Health-Syst Pharm. 1998; 55(suppl 2):S22-5.
    • (1998) Am J Health-Syst Pharm. , vol.55 , Issue.2 SUPPL.
    • Jann, M.W.1
  • 9
    • 0030052086 scopus 로고    scopus 로고
    • Selective muscarinic receptor agonists and antagonists
    • Eglen RM, Watson N. Selective muscarinic receptor agonists and antagonists. Pharmacol Toxicol. 1996; 78:59-68.
    • (1996) Pharmacol Toxicol. , vol.78 , pp. 59-68
    • Eglen, R.M.1    Watson, N.2
  • 10
    • 0025943814 scopus 로고
    • Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies
    • Levey AI, Kitt CA, Simonds WF et al. Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci. 1991; 11:3218-26.
    • (1991) J Neurosci. , vol.11 , pp. 3218-3226
    • Levey, A.I.1    Kitt, C.A.2    Simonds, W.F.3
  • 11
    • 0028924664 scopus 로고
    • Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease
    • Flynn DD, Ferrari-DiLeo G, Mash DC et al. Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem. 1995; 64:1888-91.
    • (1995) J Neurochem. , vol.64 , pp. 1888-1891
    • Flynn, D.D.1    Ferrari-DiLeo, G.2    Mash, D.C.3
  • 12
    • 0030902127 scopus 로고    scopus 로고
    • Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease
    • Bodick NC, Offen WW, Levey AI et al. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease. Arch Neurol. 1997; 54:465-73.
    • (1997) Arch Neurol. , vol.54 , pp. 465-473
    • Bodick, N.C.1    Offen, W.W.2    Levey, A.I.3
  • 13
    • 0029050694 scopus 로고
    • The safety and tolerability of CI-979 in patients with Alzheimer's disease
    • Sramek JJ, Sedman AJ, Reece PA et al. The safety and tolerability of CI-979 in patients with Alzheimer's disease. Life Sci. 1995; 57:503-10.
    • (1995) Life Sci. , vol.57 , pp. 503-510
    • Sramek, J.J.1    Sedman, A.J.2    Reece, P.A.3
  • 14
    • 0029081632 scopus 로고
    • Safety and tolerability of xanomeline tartrate in patients with Alzheimer's disease
    • Sramek JJ, Hurley DJ, Wardle TS et al. Safety and tolerability of xanomeline tartrate in patients with Alzheimer's disease. J Clin Pharmacol. 1995; 35:800-6.
    • (1995) J Clin Pharmacol. , vol.35 , pp. 800-806
    • Sramek, J.J.1    Hurley, D.J.2    Wardle, T.S.3
  • 15
    • 0028300513 scopus 로고
    • Changes in brain glucose metabolism as a key to the pathogenesis of Alzheimer's disease
    • Meier-Ruge W, Bertoni-Freddari C, Iwangoff P. Changes in brain glucose metabolism as a key to the pathogenesis of Alzheimer's disease. Gerontology. 1994; 40:246-52.
    • (1994) Gerontology , vol.40 , pp. 246-252
    • Meier-Ruge, W.1    Bertoni-Freddari, C.2    Iwangoff, P.3
  • 16
    • 0030998896 scopus 로고    scopus 로고
    • The search for disease-modifying treatment for Alzheimer's disease
    • Aisen PS, Davis KL. The search for disease-modifying treatment for Alzheimer's disease. Neurology. 1997; 48(suppl 6):S35-41.
    • (1997) Neurology , vol.48 , Issue.6 SUPPL.
    • Aisen, P.S.1    Davis, K.L.2
  • 17
    • 0031051509 scopus 로고    scopus 로고
    • Smoking and oestrogen-replacement therapy as protective factors for Alzheimer's disease
    • Letter
    • Lerner A, Koss E, Debanne S et al. Smoking and oestrogen-replacement therapy as protective factors for Alzheimer's disease. Lancet. 1997; 349:403-4. Letter.
    • (1997) Lancet , vol.349 , pp. 403-404
    • Lerner, A.1    Koss, E.2    Debanne, S.3
  • 18
    • 0032521479 scopus 로고    scopus 로고
    • Progression in the management of Alzheimer's disease
    • Smith AL, Whitehouse PJ. Progression in the management of Alzheimer's disease. Hosp Pract. 1998; 33:151-4.
    • (1998) Hosp Pract. , vol.33 , pp. 151-154
    • Smith, A.L.1    Whitehouse, P.J.2
  • 19
    • 0028448282 scopus 로고
    • Tacrine: A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease
    • Wagstaff AJ, McTavish D. Tacrine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease. Drugs Aging. 1994; 4:510-40.
    • (1994) Drugs Aging , vol.4 , pp. 510-540
    • Wagstaff, A.J.1    McTavish, D.2
  • 20
    • 0031842292 scopus 로고    scopus 로고
    • Metrifonate treatment of the cognitive deficits of Alzheimer's disease
    • Cummings JL, Cyrus PA, Bieber F et al. Metrifonate treatment of the cognitive deficits of Alzheimer's disease. Neurology. 1998; 50:1214-21.
    • (1998) Neurology , vol.50 , pp. 1214-1221
    • Cummings, J.L.1    Cyrus, P.A.2    Bieber, F.3
  • 21
    • 0029915565 scopus 로고    scopus 로고
    • Metrifonate induces cholinesterase inhibition exclusively via slow release of dichlorvos
    • Hinz VC, Grewig S, Schmidt BH. Metrifonate induces cholinesterase inhibition exclusively via slow release of dichlorvos. Neurochem Res. 1996; 21:331-7.
    • (1996) Neurochem Res. , vol.21 , pp. 331-337
    • Hinz, V.C.1    Grewig, S.2    Schmidt, B.H.3
  • 22
    • 0030035653 scopus 로고    scopus 로고
    • Long-term tacrine (Cognex) treatment: Effects on nursing home placement and mortality
    • Knopman D, Schneider L, Davis K et al. Long-term tacrine (Cognex) treatment: effects on nursing home placement and mortality. Neurology. 1996; 47:166-77.
    • (1996) Neurology , vol.47 , pp. 166-177
    • Knopman, D.1    Schneider, L.2    Davis, K.3
  • 23
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • Rogers SL, Farlow MR, Doody RS et al. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology. 1998; 50:136-45.
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3
  • 24
    • 0030967165 scopus 로고    scopus 로고
    • A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
    • Sano M, Ernesto C, Thomas RG et al. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. N Engl J Med. 1997; 336:1216-22.
    • (1997) N Engl J Med. , vol.336 , pp. 1216-1222
    • Sano, M.1    Ernesto, C.2    Thomas, R.G.3
  • 25
    • 0031943163 scopus 로고    scopus 로고
    • L-deprenyl in Alzheimer's disease: Cognitive and behavioral effects
    • Freedman M, Rewilak D, Xerri T et al. L-deprenyl in Alzheimer's disease: cognitive and behavioral effects. Neurology. 1998; 50:660-8.
    • (1998) Neurology , vol.50 , pp. 660-668
    • Freedman, M.1    Rewilak, D.2    Xerri, T.3
  • 26
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • Kawas C, Resnick S, Morrison A et al. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology. 1997; 48:1517-21.
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3
  • 27
    • 0024616703 scopus 로고
    • Rheumatoid arthritis and senile dementia of the Alzheimer's type
    • Letter
    • Jenkinson ML, Bliss MR, Brain AT et al. Rheumatoid arthritis and senile dementia of the Alzheimer's type. Br J Rheumatol. 1989; 28:86-8. Letter.
    • (1989) Br J Rheumatol. , vol.28 , pp. 86-88
    • Jenkinson, M.L.1    Bliss, M.R.2    Brain, A.T.3
  • 28
    • 0028896679 scopus 로고
    • Nonsteroidal anti-inflammatory drugs in Alzheimer's disease
    • Rich JB, Rasmusson DX, Folstein MF et al. Nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neurology. 1995; 45:51-5.
    • (1995) Neurology , vol.45 , pp. 51-55
    • Rich, J.B.1    Rasmusson, D.X.2    Folstein, M.F.3
  • 29
    • 0028289083 scopus 로고
    • Inverse association of anti-inflammatory treatments and Alzheimer's disease: Initial results of a co-twin control study
    • Breitner JCS, Gau BA, Welsh KA et al. Inverse association of anti-inflammatory treatments and Alzheimer's disease: initial results of a co-twin control study. Neurology. 1994; 44:227-32.
    • (1994) Neurology , vol.44 , pp. 227-232
    • Breitner, J.C.S.1    Gau, B.A.2    Welsh, K.A.3
  • 30
    • 0030897133 scopus 로고    scopus 로고
    • Risk of Alzheimer's disease and duration of NSAID use
    • Stewart WF, Kawas C, Corrada M et al. Risk of Alzheimer's disease and duration of NSAID use. Neurology. 1997; 48:626-32.
    • (1997) Neurology , vol.48 , pp. 626-632
    • Stewart, W.F.1    Kawas, C.2    Corrada, M.3
  • 31
    • 0030759072 scopus 로고    scopus 로고
    • A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia
    • Le Bars PL, Katz MM, Berman N et al., for the North American EGb Study Group. A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. JAMA. 1997; 278:1327-32.
    • (1997) JAMA , vol.278 , pp. 1327-1332
    • Le Bars, P.L.1    Katz, M.M.2    Berman, N.3
  • 32
    • 0030464126 scopus 로고    scopus 로고
    • New therapeutic approaches to Alzheimer's disease
    • Schneider LS. New therapeutic approaches to Alzheimer's disease. J Clin Psychiatry. 1996; 57(suppl 14):30-6.
    • (1996) J Clin Psychiatry , vol.57 , Issue.14 SUPPL. , pp. 30-36
    • Schneider, L.S.1
  • 33
    • 0029886801 scopus 로고    scopus 로고
    • Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease
    • Schneider LS, Farlow MR, Henderson VW et al. Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease. Neurology. 1996; 46:1580-4.
    • (1996) Neurology , vol.46 , pp. 1580-1584
    • Schneider, L.S.1    Farlow, M.R.2    Henderson, V.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.