Structure/antigenicity relationship of cyclic and linear peptides mimicking the V3 loop of HIV2 envelope glycoprotein

Research in Virology

Volumn 149, Issue 6, 1998, Pages 363-373

  Belhadj Jrad, B ^a   Massou, S ^b   Czaplicki, J ^b   Moureau, C ^a   Moynier, M ^a   Fourquet, P ^c   Milon, A ^b   Mazie J C ^d   Bahraoui, E ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b Inst de Pharmacologie et de B   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d INSTITUT PASTEUR   (France)

Author keywords

Antigenicity; Glycoprotein; V3 loop; HIV2; Peptide; Structure

Indexed keywords

CYCLOPEPTIDE; PEPTIDE; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

ADSORPTION; ANTIGENICITY; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 2; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; STRUCTURE ANALYSIS; VIRUS ENVELOPE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 2; RNA VIRUSES;

EID: 0032209140     PISSN: 09232516     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2516(99)80004-1     Document Type: Article

References (36)

1. Akerlind-stopner, B., Utter, G., Mufson, M.A., Orvell, C., Lerner, R.A. & Norrby, E. (1990), A subgroup-specific antigenic site in the G protein of respiratory syncytial virus forms a disulfide-bonded loop. J. Virol., 64, 5143-5148.
2. Albert, J., Stalhandske, P., Marquina, S., Karis, J., Fouchier, R.A.M., Norrby, E. & Chiodi, F. (1996), Biological phenotype of HIV type 2 isolates correlates with V3 genotype. AIDS Res. Hum. Retroviruses, 12, 821-828.
3. Atherton, E., Fox, H., Markiss, D., Logan, C.S., Sheppard, R.C. & Williams, B.J. (1978), Polyamide supports for polypeptide synthesis. J. Chem. Soc. Chem. Comm., 537-539.
4. Babas, T., Benichou, S., Guétard, D., Montagnier, L. & Bahraoui, E. (1994), Specificity of antipeptide antibodies produced against V2 and V3 regions of the external envelope of human immunodeficiency virus type 2. Mol. Immunol., 31, 361-369.
5. Bäyon-Auboyer, M.-H., Boussin, F.D., Vogt, G., Le Grand, R., Vaslin, B., Nicol-Jourdain, I. & Dormont, D. (1994), Evolution of the human immunodeficiency virus type 2 envelope gene in preimmunized and persistently infected rhesus macaques. J. Virol., 68, 3415-3420.
6. Belhadj Jrad, B. & Bahraoui, E. (1997), Linear and cyclic peptides mimicking the disulfide loops in the HIV-2 envelope glycoprotein induced antibodies with different specificity. Mol. Immunol., 34, 1177-1189.
7. Bhat, T.N., Bentley, G.A., Fischmann, T.O., Boulot, G. & Poljak, R.J. (1990), Small rearrangements in structures of Fv and Fab fragments of antibody D 1.3 on antigen binding. Nature, 347, 483-485.
8. Björling, E., Broliden, K., Bernardi, D., Utter, G., Thorstensson, R., Chiodi, F. & Norrby, E. (1991), Hyperimmune antisera against synthetic peptides representing the glycoprotein of human immunodeficiency virus type 2 can mediate neutralization and antibody-dependent cytotoxic activity. Proc. Nat. Acad. Sci. USA., 88, 6082-6086.
9. Böttiger, B., Karlsson, A., Andreasson, P., Nauclér, A., Mendes Costa, C., Norrby, B. & Biberfeld, G. (1990), Envelope cross-reactivity between human immunodeficiency virus type 1 and 2 detected by different serological methods: correlation between cross-neutralization and reactivity against the main neutralizing site. J. Virol., 64, 3492-3499.
10. Catasti, P., Fontenot, J.D., Bradbury, E.M. & Gupta, G. (1995), Local and global structural properties of the HIV-MN V3 loop. J. Biol. Chem., 270, 2224-2232.
11. Chamat, S., Nara, P., Berquist, L., Whalley, A., Morrow, W.J.W., Köhler, H. & Kang, C.Y. (1992), Two major groups of neutralizing anti-gp120 antibodies exist in HIV-infected individuals: evidence for epitope diversity around the CD4 attachment site. J. Immunol., 149, 649-654.
12. Chandrasekhar, K., Profy, A.T. & Dyson, H.J. (1991), Solution conformational preferences of immunogenic peptides derived from the principal neutralizing determinant of the HIV-1 envelope glycoprotein gp120. Biochemistry, 30, 9187-9194.
13. Colman, P.M. (1988), Structure of antibody-antigen complexes: implications for immune recognition. Adv. Immunol., 43, 66-132.
14. Davies, D.R., Padlan, E.A. & Sheriff, S. (1990), Antibody-antigen complexes. Annu. Rev. Biochem., 59, 439-473.
15. Dorow, D.S., Shi, P.T., Carbone, F.R., Minasian, E., Todd, P.E.E. & Leach, S.J. (1985), Two large immunogenic and antigenic myoglobin peptides and the effects of cyclisation. Molecular Immunology, 22, 1255-1264.
16. Ellman, G.L. (1959), Tissue sulfhydryl groups. Arch. Biochem. Biophys., 82, 70-77.
17. Emini, E.A., Schleif, W.A., Nunberg, J.H., Conley, A.J., Eda, Y., Tokiyoshi, S., Putney, S.D., Matshushita, S., Cobb, K.E., Jett, C.M., Eichberg, J.W. & Murthy, K.K. (1992), Prevention of HIV-1 infection in chimpanzees by gp120 V3 domain-specific monoclonal antibody. Nature, 355, 728-730.
18. Freed, E.O. & Myers, D.J. (1992), Identification and characterization of fusion and processing domains of the human immunodeficiency virus type 2 envelope glycoprotein. J. Virol., 66, 5472-5478.
19. Ghiara, J.B., Stura, E.A., Stanfield, R.L., Profy, A.T. & Wilson, I.A. (1993), Crystal structure of the principal neutralization site of HIV-1. Science, 264, 82-85.
20. Javaherian, K., Langlois, A.J., LaRosa, G.J., Profy, A.T., Bolognesi, D.P., Herlihy, W.C., Putney, S.D. & Matthews, T.J. (1990), Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1. Science, 250, 1590-1593.
21. Joisson, C., Kuster, F., Plaué, S. & Van Regenmortel, M.H.V. (1993), Antigenic analysis of bean pod mottle virus using linear and cyclized synthetic peptides. Arch. Virol., 128, 299-317.
22. Markert, R.L.M., Ruppach, H., Gehring, S., Dietrich, U., Mierke, D.F., Köck, M., Rübsamen-Waigmann, H. & Griesinger, C. (1996), Secondary structural elements as a basis for antibody recognition in the immunodominant region of human immunodeficiency viruses 1 and 2. Eur. J. Biochem., 237, 188-204.
23. Matsushita, S., Matsumi, S., Yoshimura, K., Morikita, T., Murakami, T. & Takatsuki, K. (1995), Neutralizing monoclonal antibodies against human immunodeficiency virus type 2 gp120. J. Virol., 69, 3333-3340.
24. McKnight, A., Shotton, C., Cordell, J., Jones, L, Simmons, G. & Clapham, P.R. (1996), Location, exposure, and conservation of neutralizing epitopes on human immunodeficiency virus type 2 SU glycoprotein. J. Virol., 70, 4598-4606.
25. Merrifield, R.B. (1986), Solid phase synthesis. Science, 232, 341-347.
26. Norrby, E., Putkonen, P., Böttiger, B., Utter, G. & Bibberfeld, G. (1991), Comparison of linear antigenic sites in the envelope proteins of human immunodeficiency virus (HIV) type 2 and type 1. AIDS Res. Hum. Retroviruses, 7, 279-285.
27. Richalet-Sécordel, P.M., Deslandres, A., Plaué, S., You, G,B., Barré-Sinoussi, F. & Van Regenmortel, M.H.V. (1994a), Cross-reactive potential of rabbit antibodies raised against a cyclic peptide representing a chimeric V3 loop of HIV-1 gp120 studied by Biosensor technique and ELISA. FEMS Immunol. Med. Microbiol., 9, 77-88.
28. Richalet-Sécordel, P.M., Zeder-Lutz, G., Plaué, S., Sommermeyer-Leroux, G. & Van Regenmortel, M.H.V. (1994b), Cross-reactivity of monoclonal antibodies to a chimeric V3 peptide of HIV-1 with peptide analogues studied by Biosensor technology and ELISA. J. Immunol. Methods, 176, 221-234.
29. Robert-Guroff, M., Aldrich, K., Muldoon, R., Stern, T.L., Bansal, G.P., Matthews, T.J., Marckham, P.D., Gallo, R.C. & Franchini, G. (1992), Cross-neutralization of human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus isolates. J. Virol., 66, 3602-3608.
30. Schulze-Gahmen, U., Klenk, H.D. & Beyreuther, K. (1986), Immunogenicity of loop-structured short synthetic peptides mimicking the antigenic site A of influenza virus hemagglutinin. Eur. J. Biochem., 159, 283-289.
31. Stanfield, R.L., Fieser, T.M., Lerner, R.A. & Wilson, I.A. (1990), Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8A. Science, 248, 712-719.
32. Traincard, F., Rey-Cuillé, M.A., Huon, I., Dartevelle, S., Mazié, J.C. & Benichou, S. (1994), Characterization of monoclonal antibodies to human immunodeficiency virus type 2 envelope glycoproteins. AIDS Res. Hum. Retroviruses, 10, 1659-1667.
33. Van der Werf, S., Briand, J.P., Plaué, S., Burckard, J., Girard, M. & Van Regenmortel, M.H.V. (1994), Ability of linear and cyclic peptides of neutralization antigenic site 1 of poliovirus type 1 to induce virus cross-reactive and neutralizing antibodies. Res. Virol., 145, 349-359.
34. Vuilleumier, S. & Mutter, M. (1992), Antigen mimicry with synthetic peptides, in "Structure of antigens" (Ed. M.H.V. Van Regenmortel), CRC Press, Boca Raton, Florida.
35. Weiss, R.A., Clapman, P.R., Weber, J.N., Whitber, D., Tedder, R.S., O'Connor, T., Chamaret, S. & Montagnier, L. (1988), HIV-2 antisera cross-neutralize HIV-1. AIDS, 2, 95-100.
36. Zagury, J.F., Franchini, G., Reitz, M., Collalti, E., Starcich, B., Hall, L., Fargnoli, K., Jagodzinski, L., Guo, H.G., Laure, F., Arya, S.K., Josephs, S., Zagury, D., Wong-Staal, F. & Gallo, R.C. (1988), Genetic variability between isolates of human immunodeficiency virus (HIV) type 2 is comparable to the variability among HIV type 1. Proc. Nat. Acad. Sci., USA, 85, 5941-5945.