Drug-activated multiple pathways of defensin mRNA regulation in HL-6O cells are defined by reversed roles of participating protein kinases

Leukemia Research

Volumn 22, Issue 10, 1998, Pages 913-925

  Herwig, Susanne ^a,b   Su, Qin ^a,b   Tempst, Paul ^a  

^a Mem Sloan Kettering Cancer C   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

Defensin; Granulocytic; HL 60 cells; Kinases; Retinoic acid

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEFENSIN; DIMETHYL SULFOXIDE; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RETINOIC ACID;

ARTICLE; CELL DIFFERENTIATION; CELL STRAIN HL 60; ENZYME ACTIVITY; ENZYME INHIBITION; GENETIC TRANSCRIPTION; GRANULOCYTE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

ANTINEOPLASTIC AGENTS; BLOOD BACTERICIDAL ACTIVITY; BLOOD PROTEINS; CELL DIFFERENTIATION; CYCLIC AMP; DEFENSINS; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; PHENOTYPE; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; RNA, MESSENGER; TRETINOIN; UP-REGULATION;

EID: 0032191470     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-2126(98)00086-1     Document Type: Article

References (69)

1. Lehrer R.I., Lichtenstein A.K., Ganz T. Defensins, antimicrobial and cytotoxic peptides of mammalian cells. Annu Rev Immunol. 11:1993;105.
2. Selsted M.E., Ouelette A.J. Defensins in granules of phagocytic and non-phagocytic cells. Trends Cell Biol. 5:1995;114.
3. Gabay J.E., Scott R.W., Campanelli D., Griffith J., Wilde C., Marra M.N., Seeger M., Nathan C.F. Antibiotic proteins of human polymorphonuclear leukocytes. Proc Natl Acad Sci USA. 86:1989;5610.
4. Ganz T., Lehrer R.I. Antimicrobial peptides of leukocytes. Curr Opin Hematol. 4:1997;53.
5. Mars W.M., Stellrecht C.M., Stass S., Frazier M.L., Saunders G.F. Localization of an abundant myeloid mRNA to individual leukocytes in mixed cell populations. Leukemia. 1:1987;167.
6. Daher K.A., Lehrer R.I., Ganz T., Kronenberg M. Isolation and characterization of human defensin cDNA clones. Proc Natl Acad Sci USA. 85:1988;7327.
7. Mars W.M., Van Tuinen P., Drabkin H.A., White J.W., Saunders G.F. A myeloid-related sequence that localizes to human chromosome 8q21.1-22. Blood. 71:1988;1713.
8. Wiedemann L.M., Francis G.E., Lamb R.F., Burns J.H., Winnie J.N., MacKenzie E.D., Birnie G.D. Differentiation stage-specific expression of a gene during granulopoiesis. Leukemia. 3:1989;227.
9. Mars W.M., Florine D.L., Talpaz M., Saunders G.F. Preferentially expressed genes in chronic myelogenous leukemia. Blood. 65:1985;1218.
10. Bateman A., Singh A., Shustik C., Mars W.M., Solomon S. The isolation and identification of multiple forms of the neutrophil granule peptides from human leukemic cells. J Biol Chem. 266:1991;7524.
11. Valore E.V., Ganz T. Posttranslational processing of defensins in immature human myeloid cells. Blood. 79:1992;1538.
12. Hirata R.K., Chen S.-T., Weil S.C. Expression of granule protein mRNAs in acute promyelocytic leukemia. Hematol Pathol. 7:1993;225.
13. Herwig S., Su Q., Zhang W., Ma Y., Tempst P. Distinct temporal patterns of defensin mRNA regulation during drug-induced differentiation of human myeloid leukemia cells. Blood. 87:1996;350.
14. Collins S.J., Ruscetti F., Gallagher R., Gallo R. Terminal differentiation of human promyelocytic leukemia cells induced by dimethylsulfoxide and other polar compounds. Proc Natl Acad Sci USA. 75:1978;2458.
15. Rovera G., Santoli D., Damsky C. Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with phorbol diester. Proc Natl Acad Sci USA. 76:1979;2779.
16. Breitman T.R., Selonick S.E., Collins S.J. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid. Proc Natl Acad Sci USA. 77:1980;2936.
17. Collins S.J. The HL-60 promyelocytic leukemia cell line: proliferation, differentiation and cellular oncogene expression. Blood. 70:1987;1233.
18. Lübbert M., Herrmann F., Koeffler H.P. Expression and regulation of myeloid-specific genes in normal and leukemic myeloid cells. Blood. 77:1991;909.
19. Koeffler H.P. Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications. Blood. 62:1983;709.
20. Love J.M., Gudas L.J. Vitamin A, differentiation and cancer. Curr Opin Cell Biol. 6:1994;825.
21. Pfahl M. Vertebrate receptors: molecular biology, dimerization and response elements. Cell Biol. 5:1994;95.
22. Linzmeier R., Michaelson D., Liu L., Ganz T. The structure of neutrophil defensin genes. FEBS Lett. 321:1993;267.
23. Orkin S.H. Transcription factors and hematopoietic development. J Biol Chem. 270:1995;4955.
24. Friedman A.D. Regulation of immature myeloid cell differentiation by PEBP2/CBF, MYB, C/EBP and ETS family members. Curr Top Microbiol Immunol. 211:1996;149.
25. Zhang D.E., Hohaus S., Voso M.T., Chen H.M., Smith L.T., Hetherington C.J., Tenen D.G. Function of PU.1, C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters. Curr Top Microbiol Immunol. 211:1996;137.
26. Pongubala J.M., Van Beveren C., Nagulapalli S., Klemsz M.J., McKercher S.R., Maki R.A., Atchison M.L. Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation. Science. 259:1993;1622.
27. Kowenz-Leutz E., Twamley G., Ansieau S., Leutz A. Novel mechanism of C/EBPβ transcriptional control: activation through derepression. Genes Dev. 8:1994;2781.
28. Boulikas T. Phosphorylation of transcription factors and control of the cell cycle. Crit Rev Eukaryotic Gene Expr. 5:1995;1.
29. Fontana J.A., Reppucci A., Durham J.P., Miranda D. Correlation between the induction of leukemic cell differentiation by various retinoids and modulation of protein kinases. Cancer Res. 46:1986;2468.
30. Okazaki T., Kato Y., Mochizuki T., Tashima M., Sawada H., Uchino H. Staurosporine, a novel kinase inhibitor, enhances HL-60 cell differentiation induced by various compounds. Exp Hematol. 16:1988;42.
31. Morin M.J., Kreutter D., Rasmussen H., Sartorelli A.C. Disparate effects of activators of protein kinase C on HL-60 promyelocytic leukemia cell differentiation. J Biol Chem. 262:1987;11758.
32. Datta R., Nakamura T., Sherman M.L., Kufe D. Regulation of junB expression by cyclic AMP (cAMP)-dependent mechanism in human myeloid cells. Blood. 78:1991;83.
33. Frank D.A., Sartorelli A.C. Alterations in tyrosine phosphorylation during granulocytic maturation of HL-60 leukemia cells. Cancer Res. 48:1988;52.
34. Bushkin I., Roth J., Heffetz D., Zick Y. pp75, a novel tyrosine-phosphorylated protein that heralds differentiation of HL-60 cells. J Biol Chem. 266:1991;11980.
35. Kingston RE, Chomczynski P, Sacchi N. Guanidinium methods for total RNA preparation. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors. Current Protocols in Molecular Biology, vol. 1. New York: Greene/Wiley-Interscience, 1995: unit 4.2.
36. Chijiwa T., Mishima A., Hagiwara M., Sano M., Hayashi K., Inoue T., Naito K., Toshioka T., Hidaka H. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. J Biol Chem. 265:1990;5267.
37. Herbert J.M., Augereau J.M., Gleye J., Maffrand J.P. Chelerythrine is a potent and specific inhibitor of protein kinase C. Biochem Biophys Res Commun. 172:1990;993.
38. O'Dell T.J., Kandel E.R., Grant S.G.N. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature. 353:1991;558.
39. Hittelman KJ, Butcher RW. Cyclic AMP and the mechanism of action of the prostaglandins. In: Cuthbert MF, editor. The Prostaglandins. Philadelphia, PA: Lippincott, 1973:151.
40. Breitman TR, Keene BR. Growth and differentiation of human promyelocytic cell line HL-60 in a defined medium. In: Sirbasku DA, Sato GH, Pardee AB, editors. Growth of Cells in Hormonally Defined Media. Cold Spring Harbor Conferences on Cell Proliferation, vol. 9. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1982:691.
41. Chaplinski T.J., Niedel J.E. Cyclic AMP levels and cellular kinetics during maturation of human promyelocytic leukemia cells. J Leukocyte Biol. 39:1986;323.
42. Olsson I.L., Breitman T.R. Induction of differentiation of the human histiocytic lymphoma cell line U-937 by retinoic acid and cyclic adenosine 3′:5′-monophosphate-inducing agents. Cancer Res. 42:1982;3924.
43. Maddox A.M., Maddox M.K. Characteristics of cyclic AMP enhancement of retinoic acid induction of increased transglutaminase activity in HL60 cells. Exp Cell Biol. 56:1988;49.
44. Chaplinski T.J., Niedel J.E. Cyclic nucleotide-induced maturation of human promyelocytic leukemia cells. J Clin Invest. 70:1982;953.
45. Moss J., Vaughan M. ADP-ribosylation of guanyl nucleotide-binding regulatory proteins by bacterial toxins. Adv Enzymol. 61:1988;303.
46. Kaur G., Viallet J., Laborda J., Blair O., Gazdar A.F., Minna J.D., Sausville E.A. Growth inhibition by cholera toxin of human lung carcinoma cell lines: correlation with GM1 ganglioside expression. Cancer Res. 52:1992;3340.
47. Elias L., Stewart T. Subcellular distribution of cyclic adenosine 3′:5′-monophosphate-dependent protein kinase during the chemically induced differentiation of HL-60 cells. Cancer Res. 44:1984;3075.
48. Ludwig K.W., Lowey B., Niles R.M. Retinoic acid increases cyclic AMP-dependent protein kinase activity in murine melanoma cells. J Biol Chem. 255:1980;5999.
49. Gianni M., Teroa M., Sozzani S., Garattini E. Retinoic acid and cyclic AMP synergistically induce the expression of liver/bone/kidney-type alkaline phosphatase gene in L929 fibroblastic cells. Biochem J. 296:1993;67.
50. Plet A., Gerbaud P., Sherman M.I., Anderson W.B., Evain Brion D. Retinoic acid effect on cyclic AMP-dependent protein kinases in embryonal carcinoma cells: studies with differentiation-defective sublines. J Cell Physiol. 127:1986;341.
51. Robertson K.A., Emami B., Collins S.J. Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity. Blood. 80:1992;1885.
52. Barker K.A., Orkin S.H., Newburger P.E. Expression of the X-CGD gene during induced differentiation of myeloid leukemia cell line HL-60. Mol Cell Biol. 8:1988;2804.
53. Segal A.W., Abo A. The biochemical basis of the NADPH oxidase of phagocytes. Trends Biochem Sci. 18:1993;43.
54. Imaizumi M., Breitman T.R. Retinoic acid-induced differentiation of the human promyelocytic cell line, HL-60, and fresh human leukemia cells in primary culture: a model for differentiation inducing therapy of leukemia. Eur J Hematol. 38:1987;289.
55. Tanaka Y., Yoshihara K., Tsuyuki M., Itaya-Hironaka A., Inada Y., Kamiya T. Retinoic acid-specific induction of protein kinase C isoform during differentiation of HL-60 cells. J Biochem. 111:1991;265.
56. Gruber J.R., Ohno S., Niles R.M. Increased expression of protein kinase Cα plays a key role in retinoic acid-induced melanoma differentiation. J Biol Chem. 267:1992;13356.
57. Hu L., Gudas L.J. Cyclic AMP analogs and retinoic acid influence the expression of retinoic acid receptor α, β, and γ mRNAs in F9 teratocarcinoma cells. Mol Cell Biol. 10:1990;391.
58. Scheibe R.J., Ginty D.D., Wagner J.A. Retinoic acid stimulates differentiation of PC12 cells that are deficient in cAMP-dependent protein kinase. J Cell Biol. 113:1991;1173.
59. Jiang H., Colbran J.L., Francis S.H., Corbin J.D. Direct evidence for cross-activation of cGMP-dependent protein kinase by cAMP in pig coronary arteries. J Biol Chem. 267:1992;1015.
60. Zhong H., SuYang H., Erdjument-Bromage H., Tempst P., Ghosh S. The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell. 89:1997;413.
61. Chen D., Rothenberg E.V. Targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles. J Exp Med. 179:1994;931.
62. Neumann M., Grieshammer T., Chuvpilo S., Kneitz B., Lohoff M., Schimpl A., Franza B.R., Serfling E. RelA/p65 is a molecular target for the immunosuppressive action of protein kinase A. EMBO J. 14:1995;1991.
63. Ollivier V., Parry G.C.N., Cobb R.R., de Prost D., Mackman N. Elevated cyclic AMP inhibits NF-κB-mediated transcription in human monocytic cells and endothelial cells. J Biol Chem. 271:1996;20828.
64. Nakamura T., Datta R., Sherman M.L., Kufe D. Regulation of c-jun gene expression by cAMP in HL-60 myeloid leukemia cells. J Biol Chem. 265:1990;22011.
65. Lehrer R.I., Szklarek D., Selsted M.E., Fleischmann J. Increased content of microbicidal cationic peptides in rabbit alveolar macrophages elicited by complete Freund adjuvant. Infect Immun. 33:1981;775.
66. Kato J.Y., Matsuoka M., Polyak K., Massague J., Sherr C.J. Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27kip1) of cyclin-dependent kinase 4 activation. Cell. 79:1994;487.
67. Wu J., Dent P., Jelinek T., Wolfman A., Weber M.J., Sturgill T.W. Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science. 262:1993;1065.
68. Cook S.J., McCormick F. Inhibition by cAMP of ras-dependent activation of raf. Science. 262:1993;1069.
69. Lalli E., Sassoni-Corsi P. Signal transduction and gene regulation: the nuclear response to cAMP. J Biol Chem. 269:1994;17359.