Shear-induced platelet activation and platelet-neutrophil aggregate formation by equine platelets

American Journal of Veterinary Research

Volumn 59, Issue 10, 1998, Pages 1243-1246

  Weiss, Douglas J ^a   Evanson, Oral A ^a   McClenahan, David ^a   Fagliari, José ^a   Walcheck, Bruce ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; PADGEM PROTEIN;

ANIMAL; ANIMAL DISEASE; ANIMAL EXPERIMENT; ARTICLE; BLOOD; BLOOD RHEOLOGY; BLOOD VISCOSITY; CELL AGGREGATION; CELL SIZE; CYTOLOGY; HEMATOCRIT; HORSE; METABOLISM; NEUTROPHIL; PHYSIOLOGY; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT;

ANIMALS; BLOOD VISCOSITY; CELL AGGREGATION; CELL SIZE; HEMATOCRIT; HEMORHEOLOGY; HORSES; MACROPHAGE-1 ANTIGEN; NEUTROPHILS; P-SELECTIN; PHYSICAL CONDITIONING, ANIMAL; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET COUNT;

EID: 0032177981     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 1990;75:550-557.
2. Evangelista V, Manarinim S, Rotondo S, et al. Platelet/polymorphonuclear leukocyte interaction in dynamic conditions - evidence of adhesion cascade and cross talk between P-selectin and the Beta-2 integrin CD11b/CD18. Blood 1996; 88:4183-4194.
3. Weber C, Springer TA. Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of MAC-1 with fibrinogen bound to alpha-IIa-beta-3 and stimulated by platelet-activating factor. J Clin Invest 1997;100: 2085-2093.
4. Weiss DJ, Evanson OA, Fagliari JJ, et al. Evaluation of platelet activation and platelet-neutrophil aggregates in Thoroughbreds undergoing near-maximal treadmill exercise. Am J Vet Res 1997;58:1376-1380.
5. Mahony C, Rantanen NW, DeMichael JA, et al. Spontaneous echocardiographic contrast in the Thoroughbred: high prevalence in racehorses and a characteristic abnormality in bleeders. Equine Vet J 1992;24:129-133.
6. Tokuue J, Hayashi J, Hata Y, et al. Enhanced platelet aggregability under high shear stress after treadmill exercise in patients with effort angina. Thromb Haemostas 1996;75:833-837.
7. Konstantopoulos K, Chow TW, Turner NA, et al. Shear stress-induced binding of von Willebrand factor to platelets. Biorheology 1997;34:57-71.
8. Holme PA, Orvim U, Hamers MJAG, et al. Shear-induced platelet activation and platelet microparticle formation at blood flow conditions as in arteries with a severe stenosis. Arterioscler Thromb Vasc Biol 1997;17:646-653.
9. Geor RJ, Weiss DJ, Smith, CM. Hemorheologic alterations induced by incremental treadmill exercise in Thoroughbreds. Am J Vet Res 1994;55:854-861.
10. Weiss DJ, Richwagen K, Evanson OA. Effects of hematocrit and erythrocyte deformability on pulmonary vascular pressures in perfused pony lung. Am J Vet Res 1996;57:346-350.
11. Weiss DJ, Evanson OA. Detection of activated platelets and platelet-leukocyte aggregates in horses. Am J Vet Res 1997;58:823-827.
12. Welles EG, Bourne C, Tyler JW, et al. Detection of activated feline platelets in platelet-rich plasma by use of fluorescein-labeled antibodies and flow cytometry. Vet Pathol 1994;31:553-560.
13. Rinder HM, Bonhan JL, Rinder CS, et al. Activated and unactivated platelet adhesion to monocytes and neutrophils. Blood 1991;78:1760-1769.
14. Rinder HM, Bonhan JL, Rinder CS, et al. Dynamics of leukocyte-platelet adhesion in whole blood. Blood 1991;78:1730-1737.
15. Somer T, Meiselman HJ. Disorders of blood viscosity. Ann Med 1993;25:31-39.
16. Marcus A. Thrombosis and inflammation as multicellular processes: pathophysiologic significance of transcellular metabolism. Blood 1990;76:1903-1907.
17. Weiss DJ, Evanson OA, McClenahan D, et al. Evaluation of platelet activation and platelet-neutrophil aggregates in ponies with alimentary laminitis. Am J Vet Res 1997;58:1375-1380.
18. Weiss DJ, Evanson OA, McClenahan D, et al. A competitive inhibitor of platelet aggregation prevents experimental equine laminitis. Am J Vet Res 1998;59:814-817.