Mouse fibroblast expressing human tyrosinase with DHICA-oxidase activity produces predominantly pheomelanin deposit in lysosome

Zoological Science

Volumn 13, Issue 6, 1996, Pages 825-831

  Kondoh, Hirofumi ^a   Wilczek, Adam ^a   Narimizu, Syuichi ^b   Mishima, Yutaka ^a  

^a Mishima Inst Dermatological Res   (Japan)

^b Sansyo Pharmaceutical Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN; MELANIN; MEMBRANE PROTEIN; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASE; PHEOMELANIN; PROTEIN; TYROSINASE RELATED PROTEIN; TYROSINASE-RELATED PROTEIN; TYRP1 PROTEIN, HUMAN; TYRP1 PROTEIN, MOUSE;

ANIMAL; ARTICLE; BIOSYNTHESIS; C3H MOUSE; CELL LINE; ELECTRON MICROSCOPY; ENZYMOLOGY; FIBROBLAST; GENETICS; HUMAN; LYSOSOME; METABOLISM; MOUSE; ULTRASTRUCTURE;

ANIMALS; CELL LINE; FIBROBLASTS; GLYCOPROTEINS; HUMANS; LYSOSOMES; MELANINS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICROSCOPY, ELECTRON; MONOPHENOL MONOOXYGENASE; OXIDOREDUCTASES; PROTEINS;

ANIMALIA;

EID: 0030435278     PISSN: 02890003     EISSN: None     Source Type: Journal    
DOI: 10.2108/zsj.13.825     Document Type: Article

References (40)

1. Ando O, Hanada S, Suemoto Y, Atobe J, Kurimoto M, Mishima Y (1993) Analyses of mixed melanogenesis in tyrosinase cDNA-transfected human amelanotic melanoma cells. J Invest Dermatol 101: 864-870
2. Bouchard B, Fuller BB, Vijayasaradhi S, Houghton AN (1989) Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA. J Exp Med 169: 2029-2042
3. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254
4. Chakraborty AK, Mishima Y, Inazu M, Hatta S, Ichihashi M (1989) Melanogenic regulatory factors in coated vesicles from melanoma cells. J Invest Dermatol 93: 616-620
5. Gomori G (1952) Microscopic Histochemistry. Principles and Practice. University of Chicago Press, Chicago, pp 189
6. Halaban R, Moellmann GE (1990) Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity. Proc Natl Acad Sci USA 87: 4909-4813
7. Hearing VJ, Jiménez (1987) Mammalian tyrosinase - The critical regulatory control point in melanocyte pigmentation. Int J Biochem 19: 1141-1147
8. Ito S, Fujita K (1985) Microanalysis of eumelanin and pheomelanin in hair and melanomas by chemical degradation and liquid chromatography. Anal Biochem 144: 527-536
9. Ito S, Wakamatsu K, Ozeki H (1993) Spectrophotometric assay of eumelanin in tissue samples. Anal Biochem 215: 273-277
10. Jiménez-Cervantes C. Solano F, Kobayashi T, Urabe K, Hearing VJ, Lozano JA, García-Borrón JC (1994) A new enzymatic function in the melanogenic pathway: The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP-1). J Biological Chem 269: 17993-18001
11. Jiménez-Cervantes C, Benedito E, Solano F, Ghanem G, Marmol V, García-Borrón JC (1995) Substrate specificity of human tyrosinase (abstr). Pigment Cell Res 8 (suppl 4): 33
12. Jackson IJ (1988) A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse. Proc Natl Acad Sci USA 85: 4392-4396
13. Jackson IJ, Chambers DM, Tsukamoto K, Copeland NG, Gilbert DJ, Jenkins NA, Hearing VJ (1992) A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO J 11: 527-535
14. Karasuyama H, Tohyama N, Tada T (1989) Autocrine growth and tumorigenicity of interleukin 2 dependent helper T cells transfected with IL-2 gene. J Exp Med 169: 13-25
15. Kornfeld S, Mellman I (1989) The biogenesis of lysosomes. Ann Rev Cell Biol 5: 483-525
16. Le Poole IC, van den Wijngaard RMJGJ, Westerhof W, Yerkruisen RP, Dutrieux RP, Dingemans KP, Das PK (1993) Phagocytosis by normal human melanocytes in vitro. Exp Cell Res 205: 388-395
17. Mishima Y (1993, 1994) Molecular and biological control of melanogenesis through tyrosinase genes and intrinsic and extrinsic regulatory factors. Pigment Cell Res 7: 376-387. Presented as Presidential Address at XVth Int. Pigment Cell Conf., London, Sep. 26-30, 1993
18. Mishima Y (1993, 1994) Molecular and biological control of melanogenesis through tyrosinase genes and intrinsic and extrinsic regulatory factors. Pigment Cell Res 7: 376-387. Presented as Presidential Address at XVth Int. Pigment Cell Conf., London, Sep. 26-30, 1993
19. Novikoff AB, Albala A, Biempica L (1968) Ultrastructural and cytochemical observations on B16 and Harding Passey mouse melanosomes: the origin of premelanosomes and compound melanosomes. J Histchem Cytochem 16: 299-319
20. Orlow SJ, Osber MP, Pawlek JM (1992) Synthesis and characterization of melanins from dihydroxyindole-2-carboxylic acid and dihydroxyindole. Pigment Cell Res 5: 113-121
21. Orlow SJ (1995) Melanosomes are specialized members of the lysosomal lineage of organelles. J Invest Dermatol 105: 3-7
22. Ozeki H, Ito S, Wakamatsu K, Hirobe T (1995) Chemical characterization of hair melanins in various coat-color mutants of mice. J Invest Dermatol 105: 361-366
23. Prota G (1988) Some new aspects of eumelanin chemistry. In "Advances in Pigment Cell Research" Ed by Bagnara JT, Alan R Liss, New York, pp 101-124
24. Prota G, Lamoreux ML, Muller J, Kobayashi T, Napolitano A, Vincensi MR, Sakai C, Heareing VJ (1995) Comparative analysis of melanins and melanosomes produced by various coat color mutants. Pigment Cell Res 8: 153-163
25. Quevedo WC Jr, Fitzpatrik TB, Szabo G, Jimbow K (1987) Biology of melanocytes. In "Dermatology in General Medicine, 3rd ed, Vol 1" Ed by Fitzpatrick TB, McGraw-Hill, New York, pp 224-251
26. Seiji M, Shimao K, Birbek MSC, Fitzpatrik TB (1963) Subcellular localization of melanin biosynthesis. Ann NY Acad Sci 100: 497-533
27. Seiji M, Kikuchi A (1969) Acid phosphatase activity in melanosomes. J Invest Dermatol 93: 212-216
28. Shibahara S, Tomita Y, Sakakura T, Nager C, Chaudhuri B, Müller R (1986) Cloning and expression of cDNA encoding mouse tyrosinase. Nucleic Acids Res 14: 2413-2427
29. Takeda A, Tomita Y, Okinaga S, Tagami H, Shibahara S (1989) Functional analysis of the cDNA encoding human tyrosinase precursor. Biochem Biophys Res Commun 162: 984-990
30. Tsukamoto K, Jackson IJ, Urabe K, Montague PM, Hearing VJ (1992) A second tyrosinase-related protein, TRP-2, is a melanogenic enzyme termed DOPAchrome tautomerase. EMBO J 11: 519-526
31. Wilczek A, Mishima Y (1993) Regulatory factors for polymerization of melanin monomers within coated vesicles and premelanosomes in melanoma cells. Melanoma Res 3: 255-262
32. Wilczek A, Mishima Y (1995) Inhibitory effects of melanin monomers, dihydroxyindole-2-carboxylic acid (DHICA) and dihydroxyindole (DHI) on mammalian tyrosinase, with a special reference to the role of DHICA/DHI ratio in melanogenesis. Pigment Cell Res 8: 105-112
33. Wilczek A, Kondoh H, Mishima Y (1996) Composition of mammalian eumelanins : analyses of DHICA-derived units in pigments from hair and melanoma cells. Pigment Cell Res 9: 63-67
34. Winder AJ (1991) Expression of a mouse tyrosinase cDNA in 3T3 Swiss mouse fibroblasts. Biochem Biophys Res Commun 178: 739-345
35. Winder AJ, Wittbjer A, Rosengren E, Rorsman H (1993a) Fibroblasts expressing mouse c locus tyrosinase produce an authentic enzyme and synthesise phaeomelanin. J Cell Sci 104: 467-475
36. Winder AJ, Wittbjer A, Rosengren E, Rorsman H (1993b) The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts. J Cell Sci 106: 153-166
37. Wolf K, Schreiner E (1971) Melanosomal acid phosphatase. Arch Dermatol Forsch 241: 255-272
38. Zhao H, Zhao Y, Nordlund JJ, Boissy RE (1994) Human TRP-1 has tyrosine hydroxylase activity but no dopa oxidase activity. Pigment Cell Res 7: 131-140
39. Zhou BK, Boissy RE, Pifko-Hirst S, Moran DJ, Orlow SJ (1993) Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane protein band II. J Invest Dermatol 100: 110-114
40. Zhou BK, Kobayashi T, Donaien PD, Bennet DC, Hearing VJ, Orlow SJ (1994) Identification of a melanosomal matrix protein encoded by the murine si (silver) locus using "organelle scanning". Proc Natl Acad Sci USA 91: 7076-7080