Cloning and characterization of a human and murine T-cell orphan G- protein-coupled receptor similar to the growth hormone secretagogue and neurotensin receptors

Genomics

Volumn 52, Issue 2, 1998, Pages 223-229

  Tan, Carina P ^a   McKee, Karen Kulju ^a   Liu, Qingyun ^a   Palyha, Oksana C ^a   Feighner, Scott D ^a   Hreniuk, Donna L ^a   Smith, Roy G ^a   Howard, Andrew D ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; GROWTH HORMONE; GUANINE NUCLEOTIDE BINDING PROTEIN; NEUROTENSIN RECEPTOR; SYNTHETIC PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; DNA SEQUENCE; GENE EXPRESSION; GROWTH HORMONE RELEASE; HUMAN; LIGAND BINDING; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RECEPTOR GENE; RECEPTOR OCCUPANCY; SEQUENCE HOMOLOGY; START CODON; T LYMPHOCYTE; TISSUE DISTRIBUTION;

MURINAE; RODENTIA;

EID: 0032169898     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5441     Document Type: Article

References (24)

1. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
2. Bennett P. A., Thomas G. B., Howard A. D., Feighner S. D., Van der Ploeg L. H. T., Smith R. G., Robinson I. C. A. F. Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat. Endocrinology. 138:1997;4552-4557.
3. Bertherat J., Bluet-Pajot M. T., Epelbaum J. Neuroendocrine regulation of growth hormone. Eur. J. Endocrinol. 132:1995;12-24.
4. Bowers C. Y., Chang J., Monamy F. Effect of the enkephalins and enkephalin analogs on the release of pituitary hormonesin vitro. Mol. Endocrinol. 1:1977;287-292.
5. Bowers C. Y., Sartor O., Reynolds G. A. Design, synthesis and biological activity of a new synthetic hexapeptide that acts on the pituitary to specifically release growth hormone. Endocrinology. 14:1984;1537-1545.
6. Bowers C. Y., Sartor R. A., Reynolds G. A. On the actions of the growth hormone-releasing hexapeptide GHRP. Endocrinology. 128:1991;2027-2035.
7. Cheng K., Chan W. W. S., Butler B., Barrato A., Smith R. G. Evidence for a role of protein kinase-C in His-D-Trp-Ala-DPhe-Lys-amide induced growth hormone release from rat primary pituitary cells. Endocrinology. 129:1991;3337-3342.
8. Ghigo E., Arvat E., Muccioli G., Camanni F. Growth hormone-releasing peptides. Eur. J. Endocrinol. 136:1997;445-460.
9. Guan X.-M., Yu H., Palyha O. C., Kulju McKee K., Feighner S. D., Sirinathsinghji D. J. S., Smith R. G., Van der Ploeg L. H. T., Howard A. D. Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues. Mol. Brain Res. 84:1997;23-29.
10. Howard A. D., Feighner S. D., Cully D. F., Arena J. P., Liberator P. L., Rosenblum C. I., Hamelin M., Hreniuk D. L., Palyha O. C., Anderson J., Paress P. S., Diaz C., Chou M., Liu K. K., McKee K.-K., Pong S.-S., Chaung L.-Y., Elbrecht A., Dashkevicz M., Heavens R., Rigby M., Sirinathsinghji D., Dean D. C., Melillo D. G., Patchett A. A., Nargund R., Griffin P. R., DeMartino J. A., Gupta S. K., Schaeffer J. A., Smith R. G., Van der Ploeg L. H. T. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. 273:1996;974-977.
11. Kozak M. Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs. Nucleic Acids Res. 12:1984;857-872.
12. Mayo K., Godfrey P. A., Suhr S. T., Kulik D. J., Rahal J. O. Growth hormone releasing hormone: Synthesis and signalling. Recent Progress in Hormone Research. 1995;Academic Press, San Diego. p. 34-73.
13. Dowell R. S., Elias K. A., Stanley M. A. Growth hormone secretagogues: Characterization, efficacy, and minimal bioactive conformation. Proc. Natl. Acad. Sci. USA. 92:1995;11165-11169.
14. Kee K.-K., Palyha O. C., Feighner S. D., Hreniuk D. L., Tan C., Phillips M., Smith R. G., Van der Ploeg L. H. T., Howard A. D. Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol. Endocrinol. 11:1997;415-423.
15. Kee K. K., Tan C. P., Palyha O. C., Liu J., Feighner S. D., Hreniuk D. L., Smith R. G., Howard A. D., Van Der Ploeg L. H. T. Cloning and characterization of two human G protein-coupled receptor genes GPR38 and GPR39 related to the growth hormone secretagogue and neurotensin receptors. Genomics. 46:1997;426-434.
16. Patchett A. A., Nargund R. A., Tata J. R., Chen M.-M., Barakat K. J., Johnston D. B. R., Cheng K., Chan W. W.-S., Butler B., Hickey G., Jacks T., Scheim K., Pong S.-S., Chaung L.-Y. P., Chen H. Y., Frazer E., Leung K. H., Chiu S.-H. L., Smith R. G. Design and biological activities of L-163,191 MK-0677): A potent and orally active growth hormone secretagogue. Proc. Natl. Acad. Sci. USA. 92:1995;7001-7005.
17. Pong S.-S., Chaung L.-Y. P., Dean D. C., Nargund R. P., Patchett A. A., Smith R. G. Identification of a new G protein-linked receptor for growth hormone secretagogues. Mol. Endocrinol. 10:1996;57-61.
18. Reisine T., Bell G. I. Molecular biology of somatostatin receptors. Endocr. Rev. 16:1995;427-442.
19. Smith R. G., Cheng K., Schoen W. R., Pong S.-S., Hickey G., Jacks T., Butler B., Chan W. W., Chaung L.-Y. P., Judith F., Taylor J., Wyvratt M. J., Fisher M.-H. A nonpeptidyl growth hormone secretagogue. Science. 260:1993;1640-1643.
20. Smith R. G., Pong S.-S., Hickey G., Jacks T., Cheng K., Leonard R., Cohen C. J., Arena J. A., Chang C. H., Drisko J., Wyvratt M., Fisher M., Nargund R., Patchett A. A. Modulation of pulsatile GH release through a novel receptor in hypothalamus and pituitary gland. Rec. Prog. Horm. Res. 51:1996;261-286.
21. Smith R. G., Van Der Ploeg L. H. T., Howard A. D., Feighner S. D., Cheng K., Hickey G. J., Wyvratt M. J., Fisher M. H., Nargund R. P., Patchett A. A. Peptidomimetic regulation of growth hormone secretion. Endocr. Rev. 18:1997;621-645.
22. Soldata T., Schafer B. W., Perriard J. C. Alternative ribosomal initiation gives rise to chicken brain-type creatine kinase isoproteins with heterogenous amino termini. J. Biol. Chem. 265: 1990;4498-4506.
23. Strobl J. S., Thomas M. J. Human growth hormone. Pharmacol. Rev. 46: 1994;1-34.
24. Tannenbaum G. S. Neuroendocrine control of growth hormone secretion. Acta Paediatr. Scand. Suppl. 372: 1991;5-16.