Calcium influx via ionotropic glutamate receptors causes long lasting inhibition of metabotropic glutamate receptor-coupled phosphoinositide hydrolysis

Neurochemistry International

Volumn 33, Issue 3, 1998, Pages 263-270

  Facchinetti, Fabrizio ^a   Hack, Nicola J ^b   Balázs, Robert ^c  

^a KENNEDY KRIEGER INSTITUTE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cerebellar granule cells; G proteins; Inositol phosphate; Kainate; Metabotropic receptors; N methyl D aspartate

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CARBACHOL; CONCANAVALIN A; CYCLOHEXIMIDE; DIZOCILPINE; FLUORIDE SODIUM; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; IONOTROPIC RECEPTOR; KAINIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N(G) NITROARGININE; PHOSPHATIDYLINOSITIDE; QUISQUALIC ACID; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; GRANULE CELL; HYDROLYSIS; NERVE CELL PLASTICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCIUM; CELLS, CULTURED; CEREBELLUM; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GTP-BINDING PROTEINS; HYDROLYSIS; KAINIC ACID; N-METHYLASPARTATE; PHOSPHATIDYLINOSITOLS; QUINOXALINES; QUISQUALIC ACID; RATS; RATS, WISTAR; RECEPTORS, GLUTAMATE; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SODIUM FLUORIDE;

EID: 0032167611     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(98)00030-8     Document Type: Article

References (39)

1. Alaluf, S., Mulvihill, E.R., Mcilhinney, R.A.J., 1995. Rapid agonist mediated phosphorylation of the metabotropic glutamate receptor 1-alpha by protein kinase C in permanently transfected cells. FEBS Lett. 367, 301-305.
2. Aronica, E., Nicoletti, F., Condorelli, D.F., Balázs, R., 1993a. Pharmacological characterization of metabotropic glutamate receptors in cultured cerebellar granule cells. Neurochem. Res. 18, 605-612.
3. Aronica, E., Dell'Albani, P., Condorelli, D.F., Nicoletti, F., Hack, N., Balázs, R., 1993b. Mechanisms underlying developmental changes in the expression of metabotropic glutamate receptors in cultured cerebellar granule cells: homologous desensitization and interactive effects involving N-methyl-D-Aspartate receptors. Mol. Pharmacol. 44, 981-989.
4. Balázs, R., Miller, S., Romano, C., de Vries, A., Chun, Y., Cotman, C.W., 1997. Metabotropic glutamate receptor mGluR5 in astrocytes: pharmacological properties and agonist regulation. J. Neurochem. 69, 151-163.
5. 3H-inositol polyphosphate accumulation in rat cerebral cortical slices. J. Neurochem. 54, 555-561.
6. Challis, R.A.J., Mistry, R., Gray, D.W., Nahorski, S.R., 1994. Modulatory effects of NMDA on phophoinositide responses evoked by the metabotropic glutamate receptor agonist 1S,3R-ACPD in neonatal rat cerebral cortex. Br. J. Pharmacol. 112, 231-239.
7. Condorelli, D.F., Dell'Albani, P., Aronica, E., Gennazzani, A., Casabona, G., Corsaro, M., Balázs, R., Nicoletti, F., 1993. Growth conditions differently regulate the expression of AMPA receptors subunits in cultured neurones. J.Neurochem. 61, 2133-2139.
8. Courtney, M.J., Lambert, J.J., Nicholls, D.G., 1990. The interactions between plasma membrane depolarization and glutamate receptor activation in the regulation of cytoplasmic free calcium in cultured cerebellar granule cells. J. Neurosci. 10, 3873-3879.
9. Cull-Candy, S.G., Usowicz, M.M., 1987. Multiple conductance channels activated by excitatory amino acids in cerebellar neurons. Nature 325, 525-528.
10. 3H]GABA uptake as a marker for cell type in primary cultures of cerebellum and olfactory bulb. Brain Res. 199, 473-481.
11. Fisher, S.K., McEwen, E., Kunkle, C., Thompson, A.K., Slowiejko, D., 1993. Contribution of G protein activation to fluoride stimulation of phosphoinositide hydrolysis in human neuroblastoma cells. J. Neurochem. 60, 1800-1805.
12. Gallo, V., Ciotti, M.T., Coletti, A., Aloisi, F., Levi, G., 1982. Selective release of glutamate from cerebellar granule cells differentiating in culture. PNAS 79, 7919-7923.
13. Garthwaite, G., Garthwaite, J., 1986. In vitro neurotoxicity of excitatory amino acid analogues during cerebellar development. Neuroscience 17, 755-767.
14. Garthwaite, J., Garthwaite, G., Palmer, R.M., Moncada, S., 1989. NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. Eur. J. Pharmacol. 172, 413-416.
15. Green, A., Milligan, G., Dobias, S.B., 1992. Gi down regulation as a mechanism for heterologous desensitization in adipocytes. JBC 267, 3223-3229.
16. Godfrey, P.P., Taghavi, Z., 1991. The inhibition of agonist-or depolarization-evoked formation of inositol phosphate by excitatory amino acids in rat cerebral cortex is due to the neurotoxic action of this class of neurotransmitter and is mediated by sodium influx. Neuropharmacology 30, 417-422.
17. 2+ influx studies. J. Neurochem. 65, 1077-1084.
18. Hadcock, J.R., Malbon, C.C., 1993. Agonist regulation of gene expression of adrenergic receptors and G proteins. J. Neurochem. 60, 1-9.
19. Hausdorff, W.P., Caron, M.G., Lefkowitz, R.J., 1990. Turning off the signal: desensitization of beta-adrenergic receptor function. FASEB J. 4, 2881-2889.
20. 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on the subunit composition. Science 252, 851-853.
21. Hollmann, M., Heinemann, S., 1994. Cloned glutamate receptors. Ann. Rev. Neurosci. 17, 31-108.
22. Jope, R.S., 1988. Modulation of phosphoinositide hydrolysis by NaF an aluminium in rat cortical slices. J.Neurochem. 51, 1731-1736.
23. Jope, R.S., Li, X., 1989. Inhibition of inositol phospholipid synthesis and norepinephrine-stimulated hydrolysis in rat brain slices by excitatory amino acids. Biochem. Pharmacol. 4, 589-596.
24. Laduron, P.M., 1994. From receptor internalization to nuclear translocation. New targets for long-term pharmacology. Biochem. Pharmacol. 47, 3-13.
25. Morrisett, R.A., Chow, C.C., Sakaguchi, T., Shin, C., McNamara, J.O., 1990. Inhibition of muscarinic-coupled phosphoinositide hydrolysis by N-methyl-D-Aspartate is dependent on depolarization via channel activation. J. Neurochem. 54, 1517-1525.
26. Mullarney, I., Dodd, M.W., Buckley, N., Milligan, G., 1993. Agonist activation of transfected human M1 muscarinic acetyl-choline receptors in CHO cells results in down-regulation of both the receptor and the a subunit of the G-protein Gq. Biochem. J. 289, 125-131.
27. Ng, G.Y., Tragadis, J., Stevens, J., Bouvier, M., O'Dowd, B.F., George, S.R., 1995. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization. Proc. Natl. Acad. Sci. U.S.A., 92, 10157-10161.
28. O'Connor, J.J., Rowan, M.J., Anwyl, R., 1994. Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation. Nature 367, 557-559.
29. Oliva, A.M., Garcìa, A., 1995. Cyclic GMP inhibition of stimulated phosphoinositide hydrolysis in neuronal cultures. Neuroreport 6, 565-568.
30. Overstreet, L.S., Pasternak, J.F., Colley, P.A., Slater, N.T., Trommer, B.L., 1997. Metabotropic glutamate receptor mediated long-term depression in developing hippocampus. Neuropharmacology 36, 831-844.
31. Palmer, E., Monaghan, D.T., Cotman, C.W., 1988. Glutamate receptors and phosphoinositide metabolism: stimulation via quisqualate receptors is inhibited by N-methyl-D-aspartate receptor activation. Mol. Brain Res. 4, 161-165.
32. Pin, J.P., Duvoisin, R., 1995. Neurotransmitter receptors I. The metabotropic glutamate receptors: structure and functions. Neuropharmacol. 34, 1-26.
33. Resink, A., Hack, N., Boer, G.J., Balázs, R., 1994. Growth conditions differentially regulate the vulnerability of developing cerebellar granule cells to excitatory amino acids. Brain Res. 655, 222-232.
34. Rossi, P., D'Angelo E., Taglietti, V., 1996. Differential long-lasting potentiation of the NMDA and non-NMDA synaptic currents induced by metabotropic and NMDA receptor coactivation in cerebellar granule cells. Eur. J. Neurosci. 8, 1182-1189.
35. Santi, M.R., Iknomovic, S., Wroblewski, J.T., Grayson, D.R., 1994. Temporal and depolarization-induced changes in the absolute amounts of mRNAs encoding metabotropic glutamate receptors in cerebellar granule neurons in vitro. J. Neurochem. 63, 1207-1217.
36. Schoepp, D.D., 1994. Novel functions for subtypes of metabotropic glutamate receptors. Neurochem. Int. 24, 439-449.
37. Van der Valk, J.B.F., Resink, A., Balàzs, R., 1991. Membrane depolarization and the expression of glutamate receptors in cerebellar granule cells. Eur. J. Pharmacol. 201, 247-250.
38. Yi, P.L., Chang, F.C., Tsai, J.J., Hung, C.R., Gean, P.W., 1995. The involvement of metabotropic glutamate receptors in long-term depression of N-methyl-D-aspartate receptor-mediated synaptic potential in the rat hippocampus. Neurosci. Lett. 1985, 207-210.
39. Waldo, G.LK., Nothup, J.K., Perkins, J.P., Kendall Harden, T., 1983. Characterization of an altered form of the β-adrenergic receptor produced during agonist-induced desensitization. J. Biol. Chem. 25, 13900-13908.