Differential long-lasting potentiation of the NMDA and non-NMDA synaptic currents induced by metabotropic and NMDA receptor coactivation in cerebellar granule cells

European Journal of Neuroscience

Volumn 8, Issue 6, 1996, Pages 1182-1189

  Rossi, Paola ^a  

^a Istituto di Fisiologia Generale   (Italy)

Author keywords

Cerebellum; LTP; Metabotropic receptors; NMDA receptors; Patch clamp; Rat

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; DICARBOXYLIC ACID DERIVATIVE; GLUTAMATE RECEPTOR; GLYCINE DERIVATIVE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; O METHYL 4 CARBOXYPHENYLGLYCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; GRANULE CELL; LONG TERM POTENTIATION; MEMBRANE; MOSSY FIBER; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ANIMALS; BENZOATES; CEREBELLUM; CYCLOLEUCINE; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; LONG-TERM POTENTIATION; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 0029933024     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1996.tb01286.x     Document Type: Article

References (5)

1. Aronica, E., Condorelli, D. F., Nicoletti, F., Dell'Albani, P., Amico, C. and Balazs, R. (1993) Metabotropic glutamate receptors in cultured cerebellar granule cells: developmental profile. J. Neurochem., 60, 559-565.
2. Asztely, F., Wigstrom, H. and Gustafsson, B. (1992) The relative contribution of NMDA receptor channels in the expression of long-term potentiation in the hippocampal CA1 region. Eur. J. Neurosci., 4, 681-690.
3. Bashir, Z. I., Bortolotto, Z. A., Davies, C. H., Berretta, N., Irving, A. J., Seal, A. J., Henley, J. M., Jane, D. E., Watkins, J. C. and Collingridge, G. L. (1993) Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors. Nature, 363, 347-350.
4. Batchelor, A. M., Madge, D. J. and Garthwaite, J. (1995) Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices. Neuroscience, 63, 911-915.
5. Ben-Ari, Y., Aniksztejn, L. and Bregestovski, P. (1992) Protein kinase C modulation of NMDA currents: an important link for LTP induction. Trends Neurosci., 15, 333-339.