Estimation of blood flow heterogeneity in human skeletal muscle using intravascular tracer data: Importance for modeling transcapillary exchange

Annals of Biomedical Engineering

Volumn 26, Issue 5, 1998, Pages 764-774

  Vicini, Paolo ^a,b   Bonadonna, Riccardo C ^c   Lehtovirta, Mikko ^d   Groop, Leif C ^e   Cobelli, Claudio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b University of Washington   (United States)

^c UNIVERSITY OF VERONA   (Italy)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e LUND UNIVERSITY   (Sweden)

Author keywords

Flow heterogeneity; Glucose; Mathematical model; Parameter estimation; Skeletal muscle

Indexed keywords

INDOCYANINE GREEN; MANNITOL; TRITIUM;

ARTICLE; BIOLOGICAL MODEL; BLOOD FLOW VELOCITY; CAPILLARY PERMEABILITY; EXTRACELLULAR SPACE; HUMAN; MICROCIRCULATION; PHYSIOLOGY; REPRODUCIBILITY; SKELETAL MUSCLE; VASCULARIZATION;

BLOOD FLOW VELOCITY; CAPILLARY PERMEABILITY; EXTRACELLULAR SPACE; HUMANS; INDOCYANINE GREEN; MANNITOL; MICROCIRCULATION; MODELS, CARDIOVASCULAR; MUSCLE, SKELETAL; REPRODUCIBILITY OF RESULTS; TRITIUM;

EID: 0032158706     PISSN: 00906964     EISSN: None     Source Type: Journal    
DOI: 10.1114/1.64     Document Type: Article

References (33)

1. Bassingthwaighte, J. B., W. A. Dobbs, and T. Ypintsoi. Heterogeneity of myocardial blood flow. In: Myocardial Blood Flow in Man: Methods and Significance in Coronary Disease, edited by A. Maseri. Torino, Italy: Minerva Medica, 1972, pp. 197-205.
2. Bassingthwaighte, J. B., and M. Levin. Analysis of coronary outflow dilution curves for the estimation of cellular uptake rates in the presence of heterogeneous regional flows. Basic Res. Cardiol. 76:404-410, 1981.
3. Bassingthwaighte, J. B., and C. A. Goresky. Modeling in the analysis of solute and water exchange in the microvasculature. In: Handbook of Physiology, edited by E. M. Renkin and C. C. Michel, Bethesda, MD: American Physiological Society, 1984, Sec. 2, Vol. IV, pp. 549-626.
4. Bassingthwaighte, J. B., C. Y. Wang, and I. S. Chan. Bloodtissue exchange via transport and transformation by capillary endothelial cells. Circ. Res. 65:1-24, 1989.
5. Bassingthwaighte, J. B., I. S. Chan, and C. Y. Wang. Computationally efficient algorithms for convection-permeation-diffusion models for blood-tissue exchange. Ann. Biomed. Eng. 20:687-725, 1992.
6. Bronikowski, T. A., C. A. Dawson, and J. H. Linehan. Model-free deconvolution techniques for estimating vascular transport functions. Int. J. Bio-Med. Comput. 14:411-429, 1983.
7. Carson, E. R.. C. Cobelli, and L. Finkelstein. The Mathematical Modelling of Metabolic and Endocrine Systems. New York: Wiley. 1983.
8. Chan, I. S., J. B. Bassingthwaighte, and A. A. Goldstein. SENSOP: a derivative free solver for nonlinear least squares with sensitivity scaling. Ann. Biomed. Eng. 21:621-631, 1993.
9. Cobelli, C., M. P. Saccomani, E. Ferrannini, R. A. DeFronzo, R. Gelfand, and R. Bonadonna. A compartmental model to quantitate in vivo glucose transport in the human forearm. Am. J. Physiol. 257:E943-E958, 1989.
10. Gonzalez, F., and J. B. Bassingthwaighte. Heterogeneities in regional volume of distribution and flows in rabbit heart. Am. J. Physiol. 258:H1012-H1024, 1990.
11. Goresky, C. A., and M. Silverman, Effect of correction of catheter distortion on calculated sinusoidal volumes. Am. J. Physiol. 207:883-892, 1964.
12. Iversen, P. O., and G. Nicolaysen. Local blood flow and glucose uptake within resting and exercising rabbit skeletal muscle. Am. J. Physiol. 260:H1795-H1801, 1991.
13. Iversen, P. O., and G. Nicolaysen. Heterogeneous blood flow distribution within single skeletal muscles in the rabbit Role of vasomotion, sympathetic nerve activity and effect of vasodilation. Acta Physiol. Scand. 137:125-133, 1989.
14. Iversen, P. O., M. Standa, and G. Nicolaysen. Marked regional heterogeneity in blood flow within a single skeletal muscle at rest and during exercise hyperaemia in the rabbit. Acta Physiol. Scand. 136:17-28, 1989.
15. Jacquez, J. Compartmental Analysis in Biology and Medicine, 3rd ed. Ann Arbor, MI: BioMedware, 1996.
16. Kelley, D. E., M. A. Mintun, S. C. Watkins, J.-A. Simoneau, F. Jadali, A. Fredrickson, J. Beattie, and R. Theriault. The effect of non-insulin dependent diabetes mellitus and obesity on glucose transport and phosphorylation in skeletal muscle. J. Clin. Invest. 97:2705-2713, 1996.
17. King, R. B., A. Deussen, G. M. Raymond, and J. B. Bassingthwaighte. A vascular transport operator. Am. J. Physiol. 265:H2196-H2208, 1993.
18. King, R. B., G. M. Raymond, and J. B. Bassingthwaighte. Modeling blood flow heterogeneity. Ann. Biomed. Eng. 24:352-372, 1996.
19. Knopp, T. J., W. A. Dobbs, J. F. Greenleaf, and J. B. Bassingthwaighte. Transcoronary intravascular transport functions obtained via a stable deconvolution technique. Ann. Biomed. Eng. 4:44-59, 1976.
20. Kroll, K., A. Deussen, and I. R. Sweet. Comprehensive model of transport and metabolism of adenosine and S-adenosylhomocysteine in the guinea pig heart. Circ. Res. 71:590-604, 1992.
21. Lilloja, S., A. A. Young, C. L. Culter, J. L. Ivy, W. G. H. Abbott, J. K. Zawadzki, H. Yki-Jarvinen, L. Christin, T. W. Secomb, and C. Bogardus. Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. J. Clin. Invest. 80:415-424, 1987.
22. National Simulation Resource Facility. MMID4 User's Guide. Center for Bioengineering, University of Washington. 1994.
23. National Simulation Resource Facility. SIMCON User's Guide. Center for Bioengineering, University of Washington, 1995.
24. Pendergast, D. R., J. A. Krasney, A. Ellis, B. McDonald, C. Marconi, and P. Cerretelli. Cardiac output and muscle blood flow in exercising dogs. Respir. Physiol. 61:317-326, 1985.
25. Piiper, J., D. R. Pendergast, C. Marconi, M. Meyer, N. Heisler, and P. Cerretelli. Blood flow distribution in dog gastrocnemius muscle at rest and during stimulation. Am. J Physiol 58:2068-2074, 1985.
26. Rose, C. P., and C. A. Goresky. Vasomotor control of capillary transit time heterogeneity in the canine coronary circulation. Circ. Res. 39:541-554, 1976.
27. Saccomani, M. P., R. C. Bonadonna, D. M. Bier, R. A. DeFronzo, and C. Cobelli. A model to measure insulin effects on glucose transport and phosphorylation in muscle: A three-tracer study. Am. J. Physiol. 270:E170-E185, 1996.
28. 14C] deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure and normal values in the conscious and anesthetized albino rat. J. Neurochem. 28:897-916, 1977.
29. Sparacino, G., P. Vicini, R. Bonadonna, P. Marraccini, M. Lehtovirta, E. Ferrannini, and C. Cobelli. Removal of catheter distortion in multiple indicator dilution studies: A deconvolution-based method and case studies on glucose blood-tissue exchange. Med. Biol. Eng. Comput. 35:337-342, 1997.
30. Utriainen, T., P. Nuutila, T. Takala, P. Vicini, U. Ruotsalainen, T. Rönnemaa, T. Tolvanen, M. Raitakari, M. Haaparanta, O. Kirvelä, C. Cobelli, and H. Yki-Jarvinen. Intact insulin stimulation of skeletal muscle blood flow, its heterogeneity and redistribution but not of glucose uptake in noninsulin dependent diabetes mellitus. J Clin. Invest. 100:777-785, 1997.
31. Vicini, P., S. Pasinato, M. P. Saccomani, R. Bonadonna, and C. Cobelli. A multi-region distributed model of glucose kinetics in the human myocardium. In: Modeling and Control in Biomedical Systems, edited by B. W. Patterson. Madison, WI: Omnipress, 1994, pp. 229-230.
32. Vicini, P., and C. Cobelli. Parameter estimation in distributed models of blood-tissue exchange: a Monte Carlo strategy to assess precision. Ann. Biomed. Eng. 25:815-821, 1997.
33. Vicini, P., R. C. Bonadonna, T. Utriainen, P. Nuutila, M. Raitakari, H. Yki-Järvinen, and C. Cobelli. Estimation of blood flow heterogeneity distribution in human skeletal muscle from positron emission tomography. Ann. Biomed. Eng. 25:906-910, 1997.