메뉴 건너뛰기




Volumn 22, Issue 1-2, 1998, Pages 135-143

XVII. Lipid metabolism of Pneumocystis: toward the definition of new molecular targets

Author keywords

C 24 alkylated sterols; cis 9,10 Epoxy stearic acid; Lipid metabolism; Purified Pneumocystis carinii; Sterol 8 to 7 isomerase; Ubiquinone

Indexed keywords

STEARIC ACID DERIVATIVE; STEROL DERIVATIVE; UBIQUINONE; 9,10 EPOXYSTEARIC ACID; 9,10-EPOXYSTEARIC ACID; STEROL;

EID: 0032148381     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(98)00071-6     Document Type: Article
Times cited : (12)

References (31)
  • 1
    • 0020824881 scopus 로고
    • Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast auxotrophs
    • Rodriguez, R.J. and Parks, L.W. (1983) Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast auxotrophs. Arch. Biochem. Biophys. 22, 861-871.
    • (1983) Arch. Biochem. Biophys. , vol.22 , pp. 861-871
    • Rodriguez, R.J.1    Parks, L.W.2
  • 2
    • 0002407096 scopus 로고
    • Lipid biochemistry of trypanosomatids
    • (Coombs, G.H. and North, M.D., Eds.) Taylor and Francis, London
    • Haughan, P.A. and Goad, L.J. (1991) Lipid biochemistry of trypanosomatids. In: Biochemical Protozoology (Coombs, G.H. and North, M.D., Eds.), pp. 312-328. Taylor and Francis, London.
    • (1991) In: Biochemical Protozoology , pp. 312-328
    • Haughan, P.A.1    Goad, L.J.2
  • 3
    • 0023142018 scopus 로고
    • Phospholipid profile of Pneumocystis carinii and its interaction with alveolar type II epithelial cells
    • Pesanti, E.L. (1987) Phospholipid profile of Pneumocystis carinii and its interaction with alveolar type II epithelial cells. Infect. Immun. 55, 736-774.
    • (1987) Infect. Immun. , vol.55 , pp. 736-774
    • Pesanti, E.L.1
  • 5
    • 0027312429 scopus 로고
    • Total cellular fatty acid composition of cultured Pneumocystis carinii
    • Paulsrud, J.R., Queener, S.F., Bartlett, M.S. and Smith, J.W. (1993) Total cellular fatty acid composition of cultured Pneumocystis carinii. J. Clin. Microbiol. 31, 1899-1902.
    • (1993) J. Clin. Microbiol. , vol.31 , pp. 1899-1902
    • Paulsrud, J.R.1    Queener, S.F.2    Bartlett, M.S.3    Smith, J.W.4
  • 7
    • 0028534866 scopus 로고
    • Metabolism of fatty acids and amino acids by cultured Pneumocystis carinii
    • Paulsrud, J.R. and Queener, S.F. (1994) Metabolism of fatty acids and amino acids by cultured Pneumocystis carinii. J. Eukaryote. Microbiol. 41, 633-638.
    • (1994) J. Eukaryote. Microbiol. , vol.41 , pp. 633-638
    • Paulsrud, J.R.1    Queener, S.F.2
  • 9
    • 0026504535 scopus 로고
    • 120 kDa surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A
    • Zimmerman, P.E., Voelker, D.R., McCormack, F.X. and Martin, W.J. (1992) 120 kDa surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A. J. Clin. Invest. 89, 143-149.
    • (1992) J. Clin. Invest. , vol.89 , pp. 143-149
    • Zimmerman, P.E.1    Voelker, D.R.2    McCormack, F.X.3    Martin, W.J.4
  • 10
    • 0026519139 scopus 로고
    • Improved model of Pneumocystis carinii pneumonia: Induced laboratory infection in Pneumocystis-free animals
    • Boylan, C.J., and Current, W.L. (1992) Improved model of Pneumocystis carinii pneumonia: induced laboratory infection in Pneumocystis-free animals. Infect. Immun. 60, 1589-1597.
    • (1992) Infect. Immun. , vol.60 , pp. 1589-1597
    • Boylan, C.J.1    Current, W.L.2
  • 13
    • 0028056625 scopus 로고
    • Evidence for the presence of 'metabolic sterols' in Pneumocystis: Identification and initial characterization of Pneumocystis carinii sterols
    • Kaneshiro, E.S., Ellis, J.E., Jayasimhulu, K. and Beach, D.H. (1994) Evidence for the presence of 'metabolic sterols' in Pneumocystis: identification and initial characterization of Pneumocystis carinii sterols. J. Eukaryote. Microbiol. 41, 78-85.
    • (1994) J. Eukaryote. Microbiol. , vol.41 , pp. 78-85
    • Kaneshiro, E.S.1    Ellis, J.E.2    Jayasimhulu, K.3    Beach, D.H.4
  • 14
    • 0028902199 scopus 로고
    • Phospholipid composition of Pneumocystis carinii and the effects of methylprednisolone immunosuppression on rat lung lipids
    • Guo, Z. and Kaneshiro, E.S. (1995) Phospholipid composition of Pneumocystis carinii and the effects of methylprednisolone immunosuppression on rat lung lipids. Infect. Immun. 63, 1286-1290.
    • (1995) Infect. Immun. , vol.63 , pp. 1286-1290
    • Guo, Z.1    Kaneshiro, E.S.2
  • 16
    • 0029797957 scopus 로고    scopus 로고
    • Characterizations of neutral lipid fatty acids and cis-9,10-epoxy octadecanoic acid in Pneumocystis carinii carinii
    • Kaneshiro, E.S., Ellis, J.E., Guo, Z., Jayasimhulu, K., Maiorano, J.N. and Kallam, K.A. (1996) Characterizations of neutral lipid fatty acids and cis-9,10-epoxy octadecanoic acid in Pneumocystis carinii carinii. Infect. Immun. 64, 4105-4114.
    • (1996) Infect. Immun. , vol.64 , pp. 4105-4114
    • Kaneshiro, E.S.1    Ellis, J.E.2    Guo, Z.3    Jayasimhulu, K.4    Maiorano, J.N.5    Kallam, K.A.6
  • 17
    • 0029930863 scopus 로고    scopus 로고
    • Fatty acid composition of the major phospholipids of Pneumocystis carinii carinii: Comparison with those of the lungs of normal and methylprednisolone-immunosuppressed rats
    • Guo, Z., Beach, D.H. and Kaneshiro, E.S. (1996) Fatty acid composition of the major phospholipids of Pneumocystis carinii carinii: comparison with those of the lungs of normal and methylprednisolone-immunosuppressed rats. Infect. Immun. 64, 1407-1412.
    • (1996) Infect. Immun. , vol.64 , pp. 1407-1412
    • Guo, Z.1    Beach, D.H.2    Kaneshiro, E.S.3
  • 18
    • 0026251584 scopus 로고
    • Assays for testing Pneumocystis carinii viability
    • Kaneshiro, E.S., Wu, Y.-P. and Cushion, M.T. (1991) Assays for testing Pneumocystis carinii viability. J. Protozool. 38, 85S-87S.
    • (1991) J. Protozool. , vol.38
    • Kaneshiro, E.S.1    Wu, Y.-P.2    Cushion, M.T.3
  • 19
    • 0027506596 scopus 로고
    • Reliability of calcein methoxy methyl ester and ethidium homodimer or propidium iodide for viability assessment of microbes
    • Kaneshiro, E.S., Wyder, M.A., Wu, Y.-P. and Cushion, M.T. (1993) Reliability of calcein methoxy methyl ester and ethidium homodimer or propidium iodide for viability assessment of microbes. J. Microbiol. Methods 17, 1-16.
    • (1993) J. Microbiol. Methods , vol.17 , pp. 1-16
    • Kaneshiro, E.S.1    Wyder, M.A.2    Wu, Y.-P.3    Cushion, M.T.4
  • 22
    • 0022449714 scopus 로고
    • Inhibitors of fungal sterol C-24 alkylation: Importance to developmental regulation
    • Nes, W.D., Hanners, P.K. and Parish, E.L. (1986) Inhibitors of fungal sterol C-24 alkylation: importance to developmental regulation. Biochem. Biophys. Res. Commun. 139, 410-415.
    • (1986) Biochem. Biophys. Res. Commun. , vol.139 , pp. 410-415
    • Nes, W.D.1    Hanners, P.K.2    Parish, E.L.3
  • 23
    • 0031027259 scopus 로고    scopus 로고
    • Effects of steroidal allenic phosphonic acid derivatives on the parasitic protists Leishmania donovani, Leishmania mexicana mexicana and Pneumocystis carinii carinii
    • Beach, D.H., Chen, F., Cushion, M.T., Macomber, R.S., Krudy, G.A., Wyder, M.A. and Kaneshiro, E.S. (1997) Effects of steroidal allenic phosphonic acid derivatives on the parasitic protists Leishmania donovani, Leishmania mexicana mexicana and Pneumocystis carinii carinii. Antimicrob. Agents Chemother. 41, 162-168.
    • (1997) Antimicrob. Agents Chemother. , vol.41 , pp. 162-168
    • Beach, D.H.1    Chen, F.2    Cushion, M.T.3    Macomber, R.S.4    Krudy, G.A.5    Wyder, M.A.6    Kaneshiro, E.S.7
  • 24
    • 0031280468 scopus 로고    scopus 로고
    • Ubiquinone synthesis by Pneumocystis carinii: Incorporation of radiolabeled polyprenyl chain and benzoquinone ring precursors
    • Sul, D. and Kaneshiro, E.S. (1997) Ubiquinone synthesis by Pneumocystis carinii: incorporation of radiolabeled polyprenyl chain and benzoquinone ring precursors. J. Eukaryote. Microbiol. 44, 60S.
    • (1997) J. Eukaryote. Microbiol. , vol.44
    • Sul, D.1    Kaneshiro, E.S.2
  • 26
    • 0028101772 scopus 로고
    • Coenzyme Q homologs in parasitic protozoa as targets for chemotherapeutic attack
    • Ellis, J.E. (1994) Coenzyme Q homologs in parasitic protozoa as targets for chemotherapeutic attack. Parasitol. Today 10, 296-301.
    • (1994) Parasitol. Today , vol.10 , pp. 296-301
    • Ellis, J.E.1
  • 28
    • 0025037605 scopus 로고
    • Efficacy of a hydroxynaphthoquinone, 566C80, in experimental parasitic infections of AIDS pneumonitis
    • Hughes, W.T., Gray, V.L., Gutteridge, W.E., Latter, V.S. and Pudney, M. (1990) Efficacy of a hydroxynaphthoquinone, 566C80, in experimental parasitic infections of AIDS pneumonitis. Antimicrob. Agents Chemother. 34, 225-228.
    • (1990) Antimicrob. Agents Chemother. , vol.34 , pp. 225-228
    • Hughes, W.T.1    Gray, V.L.2    Gutteridge, W.E.3    Latter, V.S.4    Pudney, M.5
  • 30
    • 0002227608 scopus 로고
    • Pneumocystis carinii: Potential targets for chemotherapeutic attack
    • (Coombs, G.H. and North, M.J., Eds.) Taylor and Francis, London
    • Gutteridge, W.E. (1991) Pneumocystis carinii: potential targets for chemotherapeutic attack. In: Biochemical Protozoology (Coombs, G.H. and North, M.J., Eds.), pp. 35-51. Taylor and Francis, London.
    • (1991) In: Biochemical Protozoology , pp. 35-51
    • Gutteridge, W.E.1
  • 31
    • 0010270821 scopus 로고
    • Folate antagonists in the treatment of Pneumocystis carinii pneumonia
    • (Walzer, P.D., Ed.), 2nd edn. Marcel Dekker, New York
    • Polsen, D.C., Kovacs, J.A. and Lipschik, G.Y. (1994) Folate antagonists in the treatment of Pneumocystis carinii pneumonia. In: Pneumocystis carinii Pneumonia (Walzer, P.D., Ed.), 2nd edn., pp. 545-560. Marcel Dekker, New York.
    • (1994) In: Pneumocystis Carinii Pneumonia , pp. 545-560
    • Polsen, D.C.1    Kovacs, J.A.2    Lipschik, G.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.