Surveillance of antifolate-resistant malaria [5]

Lancet

Volumn 352, Issue 9125, 1998, Pages 406-

  Basco, L K ^a   Tahar, R ^a   Ringwald, P ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; FOLIC ACID ANTAGONIST; PYRIMETHAMINE;

CODON; GENE MUTATION; GENOTYPE; HUMAN; LETTER; MALARIA; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0032146333     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)60506-5     Document Type: Letter

References (5)

1. LK Basco P Eldin de Pécoulas CM Wilson J Le Bras A Mazabraud Point mutations in the dihydrofolate reductase-thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum Mol Biochem Parasitol 69 1995 135 138
2. P Wang M Read PFG Sims JE Hyde Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization Mol Microbiol 23 1997 979 986
3. JG Kublin RS Witzig AH Shankar Molecular assays for surveillance of antifolate-resistant malaria Lancet 351 1998 1629 1630
4. Basco LK, Tahar R, Ringwald P. Molecular basis of in vivo resistance to sulfadoxine-pyrimethamine in African adult patients infected with Plasmodium falciparum malaria parasites. Antimicrob Agents Chemother (in press).
5. P Wang CS Lee R Bayoumi Resistance to antifolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthetase and dihydrofolate reductase alleles in a large number of field samples of diverse origins Mol Biochem Parasitol 89 1997 161 177