Complement-mediated killing of Plasmodium falciparum erythrocytic schizont with antibodies to the recombinant serine repeat antigen (SERA)

Vaccine

Volumn 16, Issue 13, 1998, Pages 1299-1305

  Xin Li, Pang ^a   Horii, Toshihiro ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Adjuvant; Complement; IgG subclass; Malaria vaccine; Plasmodium falciparum; Serine repeat antigen; Synthetic gene

Indexed keywords

ALUMINUM HYDROXIDE; COMPLEMENT; FREUND ADJUVANT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; MALARIA VACCINE; PARASITE ANTIGEN; RECOMBINANT PROTEIN; SERINE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANTIGEN ANTIBODY REACTION; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DRUG POTENCY; FEMALE; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DOMAIN; SCHIZONT; SUBCUTANEOUS DRUG ADMINISTRATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; CELL DIVISION; COMPLEMENT ACTIVATION; ERYTHROCYTES; FEMALE; IMMUNE SERA; IMMUNOGLOBULIN G; MALARIA VACCINES; MALARIA, FALCIPARUM; MICE; MICE, INBRED BALB C; PLASMODIUM FALCIPARUM; RECOMBINANT PROTEINS;

EID: 0032145654     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00057-7     Document Type: Article

References (35)

1. 1 Bzik, D.J., Li, W.b., Horii, T. and Inselburg, J. Amino acid sequence of the serine-repeat antigen (SERA) of Plasmodium falciparum determined from cloned cDNA. Mol. Biochem. Parasitol. 1988, 30, 279-288.
2. 2 Perrin, L.H., Merkli, B., Loche, M., Chizzolini, C., Smart, J. and Richle, R. Antimalarial Immunity in Saimiri monkeys: immunization with surface components of asexual blood stages. J. Exp. Med. 1984, 160, 441-451.
3. 3 Knapp, B., Hundt, E., Nau, U. and Küper, H.A. Molecular cloning, genomic structure and localization in a blood stage antigen of Plasmodium falciparum characterized by a serine stretch. Mol. Biochem. Parasitol. 1989, 32, 73-84.
4. 4 Delplace, P., Fortier, B., Tronchin, G., Dubremetz, J.-F. and Vernes, A. Localization, biosynthesis, processing and isolation of a major 126 kDa antigen of the parasitophorous vacuole of Plasmodium falciparum. Mol. Biochem. Parasitol. 1987, 23, 193-201.
5. 5 Chulay, J.D., Lyon, J.A., Haynes, J.D., Meierovics, A.I., Atkinson, C.T. and Aikawa, M. Monoclonal antibody characterization of Plasmodium falciparum antigens in immune complexes formed when schizonts rupture in the presence of immune serum. J. Immunol. 1987, 139, 2768-2774.
6. 6 Fox, B.A. and Bzik, D.J. Analysis of stage-specific transcripts of the Plasmodium falciparum serine repeat antigen (SERA) gene and transcription from the SERA locus. Mol. Biochem. Parasitol. 1994, 68, 133-144.
7. 7 Lyon, J.A., Haynes, J.D., Diggs, C.L., Chulay, J.D. and Pratt-Rossiter, J.M. Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface by antibodies when schizonts mature in the presence of growth inhibitory immune serum. J. Immunol. 1986, 136, 2252-2258.
8. 8 Lyon, J.A. and Haynes, J.D. Plasmodium falciparum antigens synthesized by schizonts and stabilized at the merozoite surface when schizonts mature in the presence of protease inhibitors. J. Immunol. 1986, 136, 2245-2251.
9. 9 Delplace, P., Dubremetz, J.F., Fortier, B. and Vernes, A. A 50 kilodalton exoantigen specific to the merozoite release-reinvasion stage of Plasmodium falciparum. Mol. Biochem. Parasitol. 1985, 17, 239-251.
10. 10 Lyon, J.A., Thomas, A.W., Hall, T. and Chulay, J.D. Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes. Mol. Biochem. Parasitol. 1989, 36, 77-88.
11. 11 Perkins, M.E. and Ziefer, A. Preferential binding of Plasmodium falciparum SERA and rhoptry proteins to erythrocyte membrane inner leaflet phospholipids. Infect. Immun. 1994, 62, 1207-1212.
12. 12 Horii, T., Bzik, D.J. and Inselburg, J. Characterization of antigen-expressing Plasmodium falciparum cDNA clones that are reactive with parasite inhibitory antibodies. Mol. Biochem. Parasitol. 1988, 30, 9-18.
13. 13 Delplace, P., Bhatai, A., Cagnard, M., Camus, D., Colombet, G., Debrabant, A., Dubremetz, J.F., Deubreuil, N., Prensier, G., Fortier, B., Haq, A., Weber, J. and Vernes, A. Protein p126: a parasitophorous vacuole antigen associated with the release of Plasmodium falciparum merozoites. Biol. Cell 1988, 64, 215-221.
14. 14 Debrabant, A. and Delplace, P. Leupeptin alters the proteolytic processing of p 126, the major parasitophorous vacuole antigen of Plasmodium falciparum. Mol. Biochem. Parasitol. 1989, 33, 151-158.
15. 15 Debrabant, A., Maes, P., Delplace, P., Dubremetz, J.-F., Tartar, A. and Camus, D. Intramolecular mapping of Plasmodium falciparum p126 proteolytic fragments by N-terminal amino acid sequencing. Mol. Biochem. Parasitol. 1992, 53, 89-96.
16. 16 Higgins, D.G., McConnell, D.J. and Sharp, P.M. Malarial proteinase?. Nature 1989, 340, 604.
17. 17 Eakin, A.E., Higaki, J.N., McKerrow, J.H. and Craik, C.S. Cysteine or serine proteinase?. Nature 1989, 342, 132.
18. 18 Morimatsu, K., Morikawa, T., Tanabe, K., Bzik, D.J. and Horii, T. Sequence diversity in the amino-terminal 47 kDa fragment of the Plasmodium falciparum serine repeat antigen. Mol. Biochem. Parasitol. 1997, 86, 247-254.
19. 19 Inselburg, J., Bzik, D.J., Li, W.-B., Green, K.M., Kansopon, J., Hahm, B.K., Bathurst, I.C., Barr, P.J. and Rossan, R.N. Protective immunity induced in Aotus monkeys by recombinant SERA proteins of Plasmodium falciparum. Infect. Immun. 1991, 59, 1247-1250.
20. 20 Inselburg, J., Bathurst, I.C., Kansopon, J., Barchfeld, G.L., Barr, P.J. and Rossan, R.N. Protective immunity induced in Aotus monkeys by a recombinant SERA protein of Plasmodium falciparum: adjuvant effects on induction of protective immunity. Infect. Immun. 1993, 61, 2041-2047.
21. 21 Inselburg, J., Bathurst, I.C., Kansopon, J., Barr, P.J. and Rossan, R. Protective immunity induced in Aotus monkeys by a recombinant SERA protein of Plasmodium falciparum: further studies using SERA 1 and MF75.2 adjuvant. Infect. Immun. 1993, 61, 2048-2052.
22. 22 Sugiyama, T., Suzue, K., Okamoto, M., Inselburg, J., Tai, K. and Horii, T. Production of recombinant SERA protein of Plasmodium falciparum in Escherichia coli by using synthetic genes. Vaccine 1996, 14, 1069-1076.
23. 23 Suzue, K., Ito, M., Matsumoto, Y., Tanioka, Y. and Horii, T. Protective immunity induced in squirrel monkeys with recombinant serine repeat antigen (SERA) of Plasmodium falciparum. Parasitology Int. 1997, 46, 17-25.
24. 24 Roeffen, W., Geeraedts, F., Eling, W., Beckers, P., Kumar, N., Lensen, T. and Sauerwein, R. Transmission blockage of Plasmodium falciparum malaria by anti-Pfs230-specific antibodies is isotype dependent. Infect. Immun. 1995, 63, 467-471.
25. 25 Healer, J., McGuinness, D., Hopcroft, P., Haley, S., Carter, R. and Riley, E. Complement-mediated lysis of Plasmodium falciparum gametes by malaria-immune human sera is associated with antibodies to the gamete surface antigen Pfs230. Infect. Immun. 1997, 65, 3017-3023.
26. 26 Trager, W. and Jensen, J.B. Human malaria parasites in continuous culture. Science 1976, 193, 673-675.
27. 27 Tosta, C.E., Sedegah, M., Henderson, D.C. and Wedderburn, N. Plasmodium yoelii and Plasmodium berghei: isolation of infected erythrocytes from blood by colloidal silica gradient centrifugation. Exp. Parasitol. 1980, 50, 7-15.
28. 28 Engvall, E. and Perlmann, P. Enzyme-linked immunosorbent assay, ELISA. III. Quantitation of specific antibodies by enzyme-labeled anti-immunoglobulin in antigen-coated tubes. J. Immunol. 1972, 109, 129-135.
29. 29 Towbin, H., Staehelin, T. and Gordon, J. Electrophoretic transfer of proteins from polyacrylamide gel to nitrocellulose sheets: procedure and some applications. Proc. Natl Acad. Sci. U.S.A. 1979, 76, 4350-4354.
30. 2 sensitization of target red blood cells for lysis by complement. Mol. Immunol. 1980, 17, 699-710.
31. 31 Neuberger, M.S. and Rajewsky, K. Activation of mouse complement by mouse monoclonal antibodies. Eur. J. Immunol. 1981, 11, 1012-1016.
32. 32 Stanley, H.A., Mayes, J.T., Cooper, N.R. and Reese, R.T. Complement activation by the surface of Plasmodium falciparum infected erythrocytes. Mol. Immun. 1984, 21, 145-150.
33. 33 Grun, J.L. and Maurer, P.H. Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses. Cellu. Immunol 1989, 121, 134-145.
34. 34 Dangl, J.L., Wensel, T.G., Morrison, S.L., Stryer, L., Herzenberg, L.A. and Oi, V.T. Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodies. EMBO J. 1988, 7, 1989-1994.
35. 35 Roux, K.H., Strelets, L. and Michaelsen, T.E. Flexibility of human IgG subclasses. J. Immunol. 1997, 159, 3372-3382.