-
1
-
-
17344363384
-
2D, a native like de novo designed protein
-
of special interest. The first high resolution NMR spectroscopy structure of a designed protein of complexity discloses the key principles that control the packing of the hydrophobic core.
-
2D, a native like de novo designed protein. of special interest J Am Chem Soc. 120:1998;1138-1145 The first high resolution NMR spectroscopy structure of a designed protein of complexity discloses the key principles that control the packing of the hydrophobic core.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 1138-1145
-
-
Hill, R.B.1
Degrado, W.F.2
-
2
-
-
0030936312
-
Design of a unique protein scaffold for maquettes
-
Gibney BR, Rabanal F, Skalicky JJ, Wand AJ, Dutton PL. Design of a unique protein scaffold for maquettes. J Am Chem Soc. 119:1997;2323-2324.
-
(1997)
J Am Chem Soc
, vol.119
, pp. 2323-2324
-
-
Gibney, B.R.1
Rabanal, F.2
Skalicky, J.J.3
Wand, A.J.4
Dutton, P.L.5
-
3
-
-
0030885116
-
Structure and function of an aromatic ensemble that restricts the dynamics of the hydrophobic core of a designed helix-loop-helix dimer
-
Brive L, Dolphin GT, Baltzer L. Structure and function of an aromatic ensemble that restricts the dynamics of the hydrophobic core of a designed helix-loop-helix dimer. J Am Chem Soc. 119:1997;8596-8607.
-
(1997)
J Am Chem Soc
, vol.119
, pp. 8596-8607
-
-
Brive, L.1
Dolphin, G.T.2
Baltzer, L.3
-
4
-
-
0029899119
-
Controlling topology and native-like behavior of de novo-designed peptides: Design and characterization of antiparallel four-stranded coiled coils
-
Betz SF, DeGrado WF. Controlling topology and native-like behavior of de novo-designed peptides: design and characterization of antiparallel four-stranded coiled coils. Biochemistry. 35:1996;6955-6962.
-
(1996)
Biochemistry
, vol.35
, pp. 6955-6962
-
-
Betz, S.F.1
Degrado, W.F.2
-
6
-
-
0030593029
-
Design of a monomeric 23-residue polypeptide with defined tertiary structure
-
Struthers MD, Cheng RP, Imperiali B. Design of a monomeric 23-residue polypeptide with defined tertiary structure. Science. 271:1996;342-345.
-
(1996)
Science
, vol.271
, pp. 342-345
-
-
Struthers, M.D.1
Cheng, R.P.2
Imperiali, B.3
-
7
-
-
0002543810
-
Design and NMR analyses of compact, independently folded BBA motifs
-
Struthers M, Ottesen JJ, Imperiali B. Design and NMR analyses of compact, independently folded BBA motifs. Fold Des. 3:1998;95-103.
-
(1998)
Fold des
, vol.3
, pp. 95-103
-
-
Struthers, M.1
Ottesen, J.J.2
Imperiali, B.3
-
8
-
-
0030631493
-
The pH-dependent tertiary structure of a designed helix-loop-helix dimer
-
Dolphin GT, Baltzer L. The pH-dependent tertiary structure of a designed helix-loop-helix dimer. Fold Des. 2:1997;319-330.
-
(1997)
Fold des
, vol.2
, pp. 319-330
-
-
Dolphin, G.T.1
Baltzer, L.2
-
9
-
-
0029790914
-
Synthesis of glycopeptides and lipopeptides by chemoselective ligation
-
Cervigni SE, Dumy P, Mutter M. Synthesis of glycopeptides and lipopeptides by chemoselective ligation. Angew Chem Int Ed. 35:1995;1230-1232.
-
(1995)
Angew Chem Int Ed
, vol.35
, pp. 1230-1232
-
-
Cervigni, S.E.1
Dumy, P.2
Mutter, M.3
-
10
-
-
0002746714
-
Polypeptides with supersecondary structures as templates in rational catalyst design. Catalysis of self functionalization by designed helix-loop-helix motifs
-
Baltzer L, Lundh A-C, Broo K, Olofsson S, Ahlberg P. Polypeptides with supersecondary structures as templates in rational catalyst design. Catalysis of self functionalization by designed helix-loop-helix motifs. J Chem Soc Perkin Trans 2. 1996;1671-1676.
-
(1996)
J Chem Soc Perkin Trans 2
, pp. 1671-1676
-
-
Baltzer, L.1
Lundh A-C2
Broo, K.3
Olofsson, S.4
Ahlberg, P.5
-
11
-
-
0029789894
-
The mechanism of self-catalyzed site-selective functionalization of a designed helix-loop-helix motif
-
Broo K, Brive L, Lundh A-C, Ahlberg P, Baltzer L. The mechanism of self-catalyzed site-selective functionalization of a designed helix-loop-helix motif. J Am Chem Soc. 118:1996;8172-8173.
-
(1996)
J Am Chem Soc
, vol.118
, pp. 8172-8173
-
-
Broo, K.1
Brive, L.2
Lundh A-C3
Ahlberg, P.4
Baltzer, L.5
-
12
-
-
0027453389
-
Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides
-
Johnsson K, Allemann RK, Widmer H, Benner SA. Synthesis, structure and activity of artificial, rationally designed catalytic polypeptides. Nature. 365:1993;530-532.
-
(1993)
Nature
, vol.365
, pp. 530-532
-
-
Johnsson, K.1
Allemann, R.K.2
Widmer, H.3
Benner, S.A.4
-
13
-
-
0030700484
-
A synthetic peptide ligase
-
of special interest. A new principle in catalyst design is successfully explored and the design, synthesis and function of a novel catalyst is presented. Specificity is introduced in a rational way.
-
Severin K, Lee DH, Kennan AJ, Ghadiri MR. A synthetic peptide ligase. of special interest Nature. 389:1997;706-709 A new principle in catalyst design is successfully explored and the design, synthesis and function of a novel catalyst is presented. Specificity is introduced in a rational way.
-
(1997)
Nature
, vol.389
, pp. 706-709
-
-
Severin, K.1
Lee, D.H.2
Kennan, A.J.3
Ghadiri, M.R.4
-
15
-
-
0031587461
-
Catalysis of hydrolysis and transesterification reactions of p-nitrophenyl esters by a designed helix-loop-helix dimer
-
of special interest. Histidine-based catalysts are introduced into the field of catalyst design. The structure and function of a catalytic four-helix bundle motif is presented.
-
Broo KS, Brive L, Ahlberg P, Baltzer L. Catalysis of hydrolysis and transesterification reactions of p-nitrophenyl esters by a designed helix-loop-helix dimer. of special interest J Am Chem Soc. 119:1997;11362-11372 Histidine-based catalysts are introduced into the field of catalyst design. The structure and function of a catalytic four-helix bundle motif is presented.
-
(1997)
J Am Chem Soc
, vol.119
, pp. 11362-11372
-
-
Broo, K.S.1
Brive, L.2
Ahlberg, P.3
Baltzer, L.4
-
17
-
-
0031442682
-
Emergence of symbiosis in peptide self-replication through a hypercyclic
-
Lee DH, Severin K, Yokobayashi Y, Ghadiri MR. Emergence of symbiosis in peptide self-replication through a hypercyclic. Nature. 390:1997;591-594.
-
(1997)
Nature
, vol.390
, pp. 591-594
-
-
Lee, D.H.1
Severin, K.2
Yokobayashi, Y.3
Ghadiri, M.R.4
-
20
-
-
0032490082
-
+-His pair and arginine transition state binding in catalysis of ester hydrolysis reactions by designed helix-loop-helix motifs
-
+-His pair and arginine transition state binding in catalysis of ester hydrolysis reactions by designed helix-loop-helix motifs. J Am Chem Soc. 120:1998;4063-4068.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 4063-4068
-
-
Broo, K.S.1
Nilsson, H.2
Nilssor, J.3
Flodberg, A.4
Baltzer, L.5
-
21
-
-
0032517335
-
Substrate recognition and saturation kinetics in de novo designed histidine-based four-helix bundle catalysts
-
of special interest
-
Broo KS, Nilsson H, Nilsson J, Baltzer L. Substrate recognition and saturation kinetics in de novo designed histidine-based four-helix bundle catalysts. of special interest J Am Chem Soc. 1998; The authors present the rational design of a catalyst that is capable of substrate recognition, leading to substrate binding and saturation kinetics, and the recognition of charged and hydrophobic residues.
-
(1998)
J Am Chem Soc
-
-
Broo, K.S.1
Nilsson, H.2
Nilsson, J.3
Baltzer, L.4
-
22
-
-
0031867874
-
Site-selective control of the reactivity of surface exposed histidine residues in designed four-helix bundle catalysts
-
Broo KS, Brive L, Sott RS, Baltzer L. Site-selective control of the reactivity of surface exposed histidine residues in designed four-helix bundle catalysts. Fold Des. 3:1998;303-312.
-
(1998)
Fold des
, vol.3
, pp. 303-312
-
-
Broo, K.S.1
Brive, L.2
Sott, R.S.3
Baltzer, L.4
-
23
-
-
0030874443
-
De novo design of mercury-binding two- and three-helical bundles
-
of special interest. The first demonstration of the control of metal-ion coordination by folded polypeptides suggests that the binding energy obtained in peptide folding can be exploited for the engineering of novel and unusual properties in designed metalloproteins.
-
Dieckmann GR, McRorie DK, Tierney DL, Utschig LM, Singer CP, O'Halloran TV, Penner-Hahn JE, DeGrado WF, Pecoraro VL. De novo design of mercury-binding two- and three-helical bundles. of special interest J Am Chem Soc. 119:1997;6195-6196 The first demonstration of the control of metal-ion coordination by folded polypeptides suggests that the binding energy obtained in peptide folding can be exploited for the engineering of novel and unusual properties in designed metalloproteins.
-
(1997)
J Am Chem Soc
, vol.119
, pp. 6195-6196
-
-
Dieckmann, G.R.1
McRorie, D.K.2
Tierney, D.L.3
Utschig, L.M.4
Singer, C.P.5
O'Halloran, T.V.6
Penner-Hahn, J.E.7
Degrado, W.F.8
Pecoraro, V.L.9
-
24
-
-
0032542575
-
Metal ion induced folding of a de novo designed coiled-coil peptide
-
Kohn WD, Kay CM, Sykes BD, Hodges RS. Metal ion induced folding of a de novo designed coiled-coil peptide. J Am Chem Soc. 120:1998;1124-1132.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 1124-1132
-
-
Kohn, W.D.1
Kay, C.M.2
Sykes, B.D.3
Hodges, R.S.4
-
25
-
-
0032584314
-
Effect of four helix bundle topology on heme binding and redox properties
-
of special interest. The authors describe a highly complex designed protein that binds four hemes and induces different redox properties in each one. Based on a designed apo-protein with a well-defined tertiary structure, this model system promises to allow a thorough investigation of structure and function.
-
Gibney BR, Rabanal F, Reddy KS, Dutton PL. Effect of four helix bundle topology on heme binding and redox properties. of special interest Biochemistry. 37:1998;4635-4643 The authors describe a highly complex designed protein that binds four hemes and induces different redox properties in each one. Based on a designed apo-protein with a well-defined tertiary structure, this model system promises to allow a thorough investigation of structure and function.
-
(1998)
Biochemistry
, vol.37
, pp. 4635-4643
-
-
Gibney, B.R.1
Rabanal, F.2
Reddy, K.S.3
Dutton, P.L.4
-
26
-
-
0030961554
-
Hemoprotein models based on a covalent helix-heme-helix sandwich 1. Design, synthesis and characterisation
-
Nastri F, Lombardi A, Morelli G, Maglio O, D'Auria G, Pedone C, Pavone V. Hemoprotein models based on a covalent helix-heme-helix sandwich 1. Design, synthesis and characterisation. Chemistry Eur J. 3:1997;340-349.
-
(1997)
Chemistry Eur J
, vol.3
, pp. 340-349
-
-
Nastri, F.1
Lombardi, A.2
Morelli, G.3
Maglio, O.4
D'Auria, G.5
Pedone, C.6
Pavone, V.7
-
27
-
-
0030898830
-
III minichrome I Δ and Δ isomers
-
III minichrome I Δ and Δ isomers. Chemistry - Eur J. 3:1997;350-362.
-
(1997)
Chemistry - Eur J
, vol.3
, pp. 350-362
-
-
D'Auria, G.1
Maglio, O.2
Nastri, F.3
Lombardi, A.4
Mazzeo, M.5
Morelli, G.6
Paolillo, L.7
Pedone, C.8
Pavone, V.9
-
28
-
-
0029762859
-
Template assembled synthetic proteins (TASP) as functional mimetics of proteins
-
Mutter M, Durry P, Garrouste P, Lehmann C, Mathieu M, Peggion C, Peluso S, Razaname A, Tuchscherer G. Template assembled synthetic proteins (TASP) as functional mimetics of proteins. Angew Chem Int Ed. 35:1996;1482-1485.
-
(1996)
Angew Chem Int Ed
, vol.35
, pp. 1482-1485
-
-
Mutter, M.1
Durry, P.2
Garrouste, P.3
Lehmann, C.4
Mathieu, M.5
Peggion, C.6
Peluso, S.7
Razaname, A.8
Tuchscherer, G.9
-
29
-
-
0032573867
-
Design, synthesis and properties of a novel cytochrome b model
-
Rau HK, Haehnel W. Design, synthesis and properties of a novel cytochrome b model. J Am Chem Soc. 120:1998;468-476.
-
(1998)
J Am Chem Soc
, vol.120
, pp. 468-476
-
-
Rau, H.K.1
Haehnel, W.2
-
30
-
-
0031441458
-
De novo heme proteins from designed combinatorial libraries
-
Rojas NRL, Kamtekar S, Simons CT, McLean JE, Vogel KM, Spiro TG, Farid RS, Hecht MH. De novo heme proteins from designed combinatorial libraries. Protein Sci. 6:1997;2512-2524.
-
(1997)
Protein Sci
, vol.6
, pp. 2512-2524
-
-
Rojas, N.R.L.1
Kamtekar, S.2
Simons, C.T.3
McLean, J.E.4
Vogel, K.M.5
Spiro, T.G.6
Farid, R.S.7
Hecht, M.H.8
-
32
-
-
0002806726
-
Non-covalent control of site-selective incorporation of the pyridoxal phosphate cofactor into a folded polypeptide motif - mimicking a key step in enzymatic transamination
-
Allert M, Kjellstrand M, Broo K, Nilsson A, Baltzer L. Non-covalent control of site-selective incorporation of the pyridoxal phosphate cofactor into a folded polypeptide motif - mimicking a key step in enzymatic transamination. Chem Commun. 1998;1547-1548.
-
(1998)
Chem Commun
, pp. 1547-1548
-
-
Allert, M.1
Kjellstrand, M.2
Broo, K.3
Nilsson, A.4
Baltzer, L.5
-
33
-
-
0032192431
-
Chemo- and stereoselective glycosylation of hydroxylamine derivatives: A versatile approach to glycoconjugates
-
in press
-
Peri F, Dumy P, Mutter M. Chemo- and stereoselective glycosylation of hydroxylamine derivatives: a versatile approach to glycoconjugates. Tetrahedron. 1998;. in press.
-
(1998)
Tetrahedron
-
-
Peri, F.1
Dumy, P.2
Mutter, M.3
-
34
-
-
0003305648
-
The site-selective glycosylation of a designed helix-loop-helix polypeptide motif
-
Andersson L, Stenhagen G, Baltzer L. The site-selective glycosylation of a designed helix-loop-helix polypeptide motif. J Org Chem. 63:1998;1366-1367.
-
(1998)
J Org Chem
, vol.63
, pp. 1366-1367
-
-
Andersson, L.1
Stenhagen, G.2
Baltzer, L.3
|