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Volumn 76, Issue 1-2, 1998, Pages 19-31

A constitutively activated mutant of Gαq down-regulates EP-cadherin expression and decreases adhesion between ectodermal cells at gastrulation

Author keywords

Cadherins; Early embryogenesis; GT binding proteins; Vertebrate; Xenopus laevis

Indexed keywords

CADHERIN; GUANINE NUCLEOTIDE BINDING PROTEIN; MUTANT PROTEIN;

EID: 0032143153     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(98)00106-3     Document Type: Article
Times cited : (4)

References (51)
  • 1
    • 0030602796 scopus 로고    scopus 로고
    • The drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal
    • Alcedo J., Ayzenzon M., Von Ohlen T., Noll M., Hooper J.E. The drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal. Cell. 86:1996;221-232.
    • (1996) Cell , vol.86 , pp. 221-232
    • Alcedo, J.1    Ayzenzon, M.2    Von Ohlen, T.3    Noll, M.4    Hooper, J.E.5
  • 2
    • 0026022395 scopus 로고
    • Differential expression of two cadherins in Xenopus laevis
    • Angres B., Müller A.H.J., Kellermann J., Hausen P. Differential expression of two cadherins in Xenopus laevis. Development. 111:1991;829-844.
    • (1991) Development , vol.111 , pp. 829-844
    • Angres, B.1    Müller, A.H.J.2    Kellermann, J.3    Hausen, P.4
  • 4
    • 0028085474 scopus 로고
    • Assays for studying the functional properties of in vitro-translated Gsα subunit
    • Audigier Y. Assays for studying the functional properties of in vitro-translated Gsα subunit. Methods Enzymol. 237:1994;239-254.
    • (1994) Methods Enzymol. , vol.237 , pp. 239-254
    • Audigier, Y.1
  • 6
    • 0024356208 scopus 로고
    • Expression of cell-adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm
    • Choi Y.S., Gumbiner B. Expression of cell-adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm. J. Cell Biol. 108:1989;2449-2458.
    • (1989) J. Cell Biol. , vol.108 , pp. 2449-2458
    • Choi, Y.S.1    Gumbiner, B.2
  • 7
    • 0025904994 scopus 로고
    • Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm inducing factors, may play a role in ventral mesodermal patterning during embryogenesis
    • Christian J.L., McMahon J.A., McMahon A.P., Moon R.T. Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm inducing factors, may play a role in ventral mesodermal patterning during embryogenesis. Development. 111:1991;1045-1056.
    • (1991) Development , vol.111 , pp. 1045-1056
    • Christian, J.L.1    McMahon, J.A.2    McMahon, A.P.3    Moon, R.T.4
  • 9
    • 0023216152 scopus 로고
    • Regional specification within the mesoderm of early embryos of Xenopus laevis
    • Dale L., Slack J.M.W. Regional specification within the mesoderm of early embryos of Xenopus laevis. Development. 100:1987;279-295.
    • (1987) Development , vol.100 , pp. 279-295
    • Dale, L.1    Slack, J.M.W.2
  • 10
    • 0026717301 scopus 로고
    • Bone morphogenetic protein 4: A ventralizing factor in early Xenopus development
    • Dale L., Howes J., Price B.M.J., Smith J.C. Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development. 115:1992;573-585.
    • (1992) Development , vol.115 , pp. 573-585
    • Dale, L.1    Howes, J.2    Price, B.M.J.3    Smith, J.C.4
  • 11
    • 0025275826 scopus 로고
    • The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos
    • Detrick R., Dickey D., Kintner C.R. The effects of N-cadherin misexpression on morphogenesis in Xenopus embryos. Neuron. 4:1990;493-506.
    • (1990) Neuron , vol.4 , pp. 493-506
    • Detrick, R.1    Dickey, D.2    Kintner, C.R.3
  • 12
    • 0028106839 scopus 로고
    • Mutation of valine residue unique to α subunit of Gs abolishes activation
    • Devic E., Journot L., Pantaloni C., Bockaert J., Audigier Y. Mutation of valine residue unique to α subunit of Gs abolishes activation. J. Biol. Chem. 269:1994;20899-20904.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20899-20904
    • Devic, E.1    Journot, L.2    Pantaloni, C.3    Bockaert, J.4    Audigier, Y.5
  • 13
    • 0030273124 scopus 로고    scopus 로고
    • Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis
    • Devic E., Paquereau L., Vernier P., Knibiehler B., Audigier Y. Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis. Mech Dev. 59:1996;129-140.
    • (1996) Mech Dev. , vol.59 , pp. 129-140
    • Devic, E.1    Paquereau, L.2    Vernier, P.3    Knibiehler, B.4    Audigier, Y.5
  • 14
    • 0030273413 scopus 로고    scopus 로고
    • The mRNA encoding a β subunit of heterotrimeric GTP-binding proteins is localized to the animal pole of Xenopus laevis oocyte and embryos
    • Devic E., Paquereau L., Rizzoti K., Monier A., Knibiehler B., Audigier Y. The mRNA encoding a β subunit of heterotrimeric GTP-binding proteins is localized to the animal pole of Xenopus laevis oocyte and embryos. Mech Dev. 59:1996;141-151.
    • (1996) Mech Dev. , vol.59 , pp. 141-151
    • Devic, E.1    Paquereau, L.2    Rizzoti, K.3    Monier, A.4    Knibiehler, B.5    Audigier, Y.6
  • 15
    • 0029966537 scopus 로고    scopus 로고
    • A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-β
    • Dippel E., Kalkbrenner F., Wittig B., Schultz G. A heterotrimeric G protein complex couples the muscarinic m1 receptor to phospholipase C-β Proc. Natl. Acad. Sci. USA. 93:1996;1391-1396.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1391-1396
    • Dippel, E.1    Kalkbrenner, F.2    Wittig, B.3    Schultz, G.4
  • 16
    • 0029856722 scopus 로고    scopus 로고
    • Purification and G protein subunit regulation of a phospholipase C-β From Xenopus laevis oocytes
    • Filtz T.M., Paterson A., Harden T.K. Purification and G protein subunit regulation of a phospholipase C-β from Xenopus laevis oocytes. J. Biol. Chem. 271:1996;31121-31126.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31121-31126
    • Filtz, T.M.1    Paterson, A.2    Harden, T.K.3
  • 17
    • 0026090748 scopus 로고
    • Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos
    • Ginsberg D., DeSimone D., Geiger B. Expression of a novel cadherin (EP-cadherin) in unfertilized eggs and early Xenopus embryos. Development. 111:1991;315-322.
    • (1991) Development , vol.111 , pp. 315-322
    • Ginsberg, D.1    Desimone, D.2    Geiger, B.3
  • 18
    • 0026502740 scopus 로고
    • The generation of diversity and pattern in animal development
    • Gurdon J.B. The generation of diversity and pattern in animal development. Cell. 68:1992;185-199.
    • (1992) Cell , vol.68 , pp. 185-199
    • Gurdon, J.B.1
  • 19
    • 0022391871 scopus 로고
    • Activation of muscle-specific genes in Xenopus development by an induction between animal and vegetal cells of a blastula
    • Gurdon J.B., Fairman S., Mohun T.J., Brennan S. Activation of muscle-specific genes in Xenopus development by an induction between animal and vegetal cells of a blastula. Cell. 41:1985;913-922.
    • (1985) Cell , vol.41 , pp. 913-922
    • Gurdon, J.B.1    Fairman, S.2    Mohun, T.J.3    Brennan, S.4
  • 20
    • 0026285616 scopus 로고
    • In situ hybridization: An improved whole mount method for Xenopus embryos
    • Harland R.M. In situ hybridization: an improved whole mount method for Xenopus embryos. Methods Cell Biol. 36:1991;675-685.
    • (1991) Methods Cell Biol. , vol.36 , pp. 675-685
    • Harland, R.M.1
  • 21
    • 0026570216 scopus 로고
    • Diffusible factors in vertebrate embryonic induction
    • Jessel T.M., Melton D.A. Diffusible factors in vertebrate embryonic induction. Cell. 68:1992;257-270.
    • (1992) Cell , vol.68 , pp. 257-270
    • Jessel, T.M.1    Melton, D.A.2
  • 22
    • 0023620142 scopus 로고
    • The development of animal cap cells in Xenopus: A mesure of the start of animal cap competence to form mesoderm
    • Jones E.A., Woodland H.R. The development of animal cap cells in Xenopus: a mesure of the start of animal cap competence to form mesoderm. Development. 101:1987;557-563.
    • (1987) Development , vol.101 , pp. 557-563
    • Jones, E.A.1    Woodland, H.R.2
  • 23
    • 0019225669 scopus 로고
    • The cellular basis of epiboly: An SEM study of deep-cell rearrangement during gastrulation in Xenopus laevis
    • Keller R.E. The cellular basis of epiboly: an SEM study of deep-cell rearrangement during gastrulation in Xenopus laevis. J. Embryol. Exp. Morph. 60:1980;201-234.
    • (1980) J. Embryol. Exp. Morph. , vol.60 , pp. 201-234
    • Keller, R.E.1
  • 24
    • 0023639110 scopus 로고
    • Synergistic induction of mesoderm by FGF and TGFβ and the identification of an mRNA coding for FGF in the early Xenopus embryo
    • Kimelman D., Kirschner M.W. Synergistic induction of mesoderm by FGF and TGFβ and the identification of an mRNA coding for FGF in the early Xenopus embryo. Cell. 51:1987;369-377.
    • (1987) Cell , vol.51 , pp. 369-377
    • Kimelman, D.1    Kirschner, M.W.2
  • 25
    • 0026602806 scopus 로고
    • Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain
    • Kintner C. Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell. 69:1992;225-236.
    • (1992) Cell , vol.69 , pp. 225-236
    • Kintner, C.1
  • 26
    • 0026065742 scopus 로고
    • Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog
    • Kline D., Kopf G.S., Muncy L.F., Jaffe L.A. Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog. Xenopus laevis. Dev. Biol. 143:1991;218-229.
    • (1991) Xenopus Laevis. Dev. Biol. , vol.143 , pp. 218-229
    • Kline, D.1    Kopf, G.S.2    Muncy, L.F.3    Jaffe, L.A.4
  • 27
    • 0025981884 scopus 로고
    • Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: Analysis of mesoderm inducing activity
    • Kösster M., Plessow S., Clement J.H., Lorenz A., Tiedemann H., Knöchel W. Bone morphogenetic protein 4 (BMP-4), a member of the TGF-β family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity. Mech Dev. 33:1991;191-200.
    • (1991) Mech Dev. , vol.33 , pp. 191-200
    • Kösster, M.1    Plessow, S.2    Clement, J.H.3    Lorenz, A.4    Tiedemann, H.5    Knöchel, W.6
  • 28
    • 0022427758 scopus 로고
    • Developmental regulation of a gastrula-specific gene injected into fertilized Xenopus eggs
    • Krieg P.A., Melton D.A. Developmental regulation of a gastrula-specific gene injected into fertilized Xenopus eggs. EMBO J. 4:1985;3463-3471.
    • (1985) EMBO J. , vol.4 , pp. 3463-3471
    • Krieg, P.A.1    Melton, D.A.2
  • 29
    • 0024513250 scopus 로고
    • The mRNA encoding elongation factor 1-α (EF-1α) is a major transcript at the midblastula transition in Xenopus
    • Krieg P.A., Varnum S., Wormington M.W., Melton D.A. The mRNA encoding elongation factor 1-α (EF-1α) is a major transcript at the midblastula transition in Xenopus. Dev. Biol. 133:1989;93-100.
    • (1989) Dev. Biol. , vol.133 , pp. 93-100
    • Krieg, P.A.1    Varnum, S.2    Wormington, M.W.3    Melton, D.A.4
  • 30
    • 0028858038 scopus 로고
    • Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin
    • Lee C.-H., Gumbiner B. Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin. Dev. Biol. 171:1995;363-373.
    • (1995) Dev. Biol. , vol.171 , pp. 363-373
    • Lee, C.-H.1    Gumbiner, B.2
  • 31
    • 0028906321 scopus 로고
    • Expression cloning of siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis
    • Lemaire P., Garrett N., Gurdon J.B. Expression cloning of siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell. 81:1995;85-94.
    • (1995) Cell , vol.81 , pp. 85-94
    • Lemaire, P.1    Garrett, N.2    Gurdon, J.B.3
  • 32
    • 0028293208 scopus 로고
    • Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant
    • Levine E., Lee C.H., Kintner C., Gumbiner B.M. Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant. Development. 120:1994;901-909.
    • (1994) Development , vol.120 , pp. 901-909
    • Levine, E.1    Lee, C.H.2    Kintner, C.3    Gumbiner, B.M.4
  • 33
    • 0025905181 scopus 로고
    • Expression cloning of an activin receptor, a predicted transmembrane serine kinase
    • Matthews L.S., Vale W.W. Expression cloning of an activin receptor, a predicted transmembrane serine kinase. Cell. 65:1991;973-982.
    • (1991) Cell , vol.65 , pp. 973-982
    • Matthews, L.S.1    Vale, W.W.2
  • 34
    • 0026529503 scopus 로고
    • Cloning of a second type of activin receptor and functional characterization in Xenopus embryos
    • Matthews L.S., Vale W.W., Kintner C.R. Cloning of a second type of activin receptor and functional characterization in Xenopus embryos. Science. 255:1992;1702-1705.
    • (1992) Science , vol.255 , pp. 1702-1705
    • Matthews, L.S.1    Vale, W.W.2    Kintner, C.R.3
  • 35
    • 0026470018 scopus 로고
    • Competence modifiers synergize with growth factors during mesoderm induction and patterning in Xenopus
    • Moon R.T., Christian J.L. Competence modifiers synergize with growth factors during mesoderm induction and patterning in Xenopus. Cell. 71:1992;709-712.
    • (1992) Cell , vol.71 , pp. 709-712
    • Moon, R.T.1    Christian, J.L.2
  • 36
    • 0025000737 scopus 로고
    • Regulation of the fibroblast growth factor receptor in early Xenopus embryos
    • Musci T.J., Amaya E., Kirschner M.W. Regulation of the fibroblast growth factor receptor in early Xenopus embryos. Proc. Natl. Acad. Sci. USA. 87:1990;8365-8369.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8365-8369
    • Musci, T.J.1    Amaya, E.2    Kirschner, M.W.3
  • 37
    • 0020407569 scopus 로고
    • A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage
    • Newport J., Kirschner M. A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage. Cell. 30:1982;675-686.
    • (1982) Cell. , vol.30 , pp. 675-686
    • Newport, J.1    Kirschner, M.2
  • 39
    • 0026654469 scopus 로고
    • Regulation of inositol phospholipid-specific phospholipase C isozymes
    • Rhee S.G., Choi K.D. Regulation of inositol phospholipid-specific phospholipase C isozymes. J. Biol. Chem. 267:1992;12393-12396.
    • (1992) J. Biol. Chem. , vol.267 , pp. 12393-12396
    • Rhee, S.G.1    Choi, K.D.2
  • 40
    • 0027967380 scopus 로고
    • Xenopus chordin: A novel dorsalizing factor activated by organizer-specific homeobox genes
    • Sasai Y., Lu B., Steinbeisser H., Geissert D., Gont L., De Robertis E.M. Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell. 79:1994;779-790.
    • (1994) Cell , vol.79 , pp. 779-790
    • Sasai, Y.1    Lu, B.2    Steinbeisser, H.3    Geissert, D.4    Gont, L.5    De Robertis, E.M.6
  • 41
    • 0028302482 scopus 로고
    • Neuromedin B receptor, expressed in Xenopus laevis oocytes, selectively couples to Gαq and not Gα11
    • Shapira H., Way J., Lipinsky D., Oron Y., Battey J.F. Neuromedin B receptor, expressed in Xenopus laevis oocytes, selectively couples to Gαq and not Gα11. FEBS Lett. 348:1994;89-92.
    • (1994) FEBS Lett. , vol.348 , pp. 89-92
    • Shapira, H.1    Way, J.2    Lipinsky, D.3    Oron, Y.4    Battey, J.F.5
  • 42
    • 0023105348 scopus 로고
    • Mesoderm induction in early Xenopus embryos by heparin-binding growth factors
    • Slack J.M.W., Darlington B.G., Heath J.K., Godsave S.F. Mesoderm induction in early Xenopus embryos by heparin-binding growth factors. Nature. 326:1987;197-200.
    • (1987) Nature , vol.326 , pp. 197-200
    • Slack, J.M.W.1    Darlington, B.G.2    Heath, J.K.3    Godsave, S.F.4
  • 43
    • 0031456672 scopus 로고    scopus 로고
    • Interaction of Wnt and frizzled homologue triggers G-protein-linked phosphatidylinositol signalling
    • Slusarski D.C., Corces V.G., Moon R.T. Interaction of Wnt and frizzled homologue triggers G-protein-linked phosphatidylinositol signalling. Nature. 390:1997;410-413.
    • (1997) Nature , vol.390 , pp. 410-413
    • Slusarski, D.C.1    Corces, V.G.2    Moon, R.T.3
  • 44
    • 0026646326 scopus 로고
    • Expression cloning of noggin, a new dorsalizing factor localized in the Spemann organizer in Xenopus embryos
    • Smith J.C., Harland R.M. Expression cloning of noggin, a new dorsalizing factor localized in the Spemann organizer in Xenopus embryos. Cell. 70:1992;829-840.
    • (1992) Cell , vol.70 , pp. 829-840
    • Smith, J.C.1    Harland, R.M.2
  • 45
    • 0025829225 scopus 로고
    • Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin
    • Sokol S., Melton D.A. Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin. Nature. 351:1991;409-411.
    • (1991) Nature , vol.351 , pp. 409-411
    • Sokol, S.1    Melton, D.A.2
  • 46
    • 0025695580 scopus 로고
    • G protein diversity: A distinct class of α subunits is present in vertebrates and invertebrates
    • Strathmann M., Simon M.I. G protein diversity: a distinct class of α subunits is present in vertebrates and invertebrates. Proc. Natl. Acad. Sci. USA. 87:1990;9113-9117.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9113-9117
    • Strathmann, M.1    Simon, M.I.2
  • 47
    • 0025894092 scopus 로고
    • Cadherin cell adhesion receptors as a morphogenetic regulator
    • Takeichi M. Cadherin cell adhesion receptors as a morphogenetic regulator. Science. 251:1991;1451-1455.
    • (1991) Science , vol.251 , pp. 1451-1455
    • Takeichi, M.1
  • 48
    • 0027272511 scopus 로고
    • Processed Vg1 protein is an axial mesoderm inducer in Xenopus
    • Thomsen G.T., Melton D.A. Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell. 74:1993;433-441.
    • (1993) Cell , vol.74 , pp. 433-441
    • Thomsen, G.T.1    Melton, D.A.2
  • 49
    • 0029939701 scopus 로고    scopus 로고
    • Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development
    • Torres M.A., Yang-Snyder J.A., Purcell S.M., DeMarais A.A., McGrew L.L., Moon R.T. Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J. Cell Biol. 133:1996;1123-1137.
    • (1996) J. Cell Biol. , vol.133 , pp. 1123-1137
    • Torres, M.A.1    Yang-Snyder, J.A.2    Purcell, S.M.3    Demarais, A.A.4    McGrew, L.L.5    Moon, R.T.6
  • 50
    • 0029784223 scopus 로고    scopus 로고
    • Smoothened encodes a receptor-like serpentine protein required for hedgehog signalling
    • van den Heuvel M., Ingham P.W. smoothened encodes a receptor-like serpentine protein required for hedgehog signalling. Nature. 382:1996;547-551.
    • (1996) Nature , vol.382 , pp. 547-551
    • Van Den Heuvel, M.1    Ingham, P.W.2
  • 51
    • 0026500077 scopus 로고
    • Activation of phospholipase C by the α subunits of the Gq and G11 proteins in transfected Cos-7 cells
    • Wu D., Lee C.H., Rhee S.G., Simon M.I. Activation of phospholipase C by the α subunits of the Gq and G11 proteins in transfected Cos-7 cells. J Biol. Chem. 267:1992;1811-1817.
    • (1992) J Biol. Chem. , vol.267 , pp. 1811-1817
    • Wu, D.1    Lee, C.H.2    Rhee, S.G.3    Simon, M.I.4


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