Induction of S100b in Myocardium: An Intrinsic Inhibitor of Cardiac Hypertrophy

Canadian Journal of Applied Physiology

Volumn 23, Issue 4, 1998, Pages 377-389

  Parker, Thomas G ^a   Marks, Alexander ^b   Tsoporis, James N ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Calcium binding proteins; Cardiac myocytes; Gene expression; Growth factors; Heart failure

Indexed keywords

ACTIN; MYOSIN HEAVY CHAIN; MYOSIN IIB; NONMUSCLE MYOSIN TYPE IIB HEAVY CHAIN; PROTEIN KINASE C; PROTEIN S 100;

ANIMAL; BIOSYNTHESIS; CARDIOMEGALY; CELL CULTURE; CELL DIVISION; CYTOLOGY; DISEASE MODEL; FEEDBACK SYSTEM; FORWARD HEART FAILURE; GENE EXPRESSION REGULATION; GENETICS; HEART INFARCTION; HEART MUSCLE; HUMAN; METABOLISM; MOUSE; PHENOTYPE; PHYSIOLOGY; RAT; REVIEW; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ACTINS; ANIMALS; CARDIAC OUTPUT, LOW; CARDIOMEGALY; CELL DIVISION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEEDBACK; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOSIN HEAVY CHAINS; NONMUSCLE MYOSIN TYPE IIB; PHENOTYPE; PROTEIN KINASE C; RATS; S100 PROTEINS; SIGNAL TRANSDUCTION;

EID: 0032134019     PISSN: 10667814     EISSN: None     Source Type: Journal    
DOI: 10.1139/h98-022     Document Type: Article

References (61)

1. Albert, K.A., Wu, W.C.-S., Nairn, A.C., and Greengard, P. (1984). Inhibition by calmodulin of calcium/phospholipid-dependent protein phosphorylation. Proc. Natl. Acad. Sci. USA. 81: 3622-3625.
2. Baudier, J., Delphin, C., Grunwald, D., Khochbin, S., and Lawrence, J.J. (1992). Characterization of the tumor suppressor protein p53 as a protein kinase C substrate and a S100β-binding protein. Proc. Natl. Acad. Sci. USA. 89: 11627-11631.
3. Baudier, J., Mochly-Rosen, D., Newton, A., Lee, S.H., Koshland, D.E.J., and Cole, R.D. (1987). Comparison of S100b protein with calmodulin: Interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. Biochemistry. 26: 2886-2893.
4. Bishopric, N.H., Simpson, P.C., and Ordahl, C.P. (1987). Induction of the skeletal alpha-actin gene in alpha 1-adrenoceptor-mediated hypertrophy of rat cardiac myocytes. J. Clin. Invest. 80(4): 1194-9.
5. Black, F.M., Packer, S.E., Parker, T.G., Michael, L.H., Roberts, R., Schwartz, R.J., and Schneider, M.D. (1991). The vascular smooth muscle alpha-actin gene is reactivated during cardiac hypertrophy provoked by load. J. Clin. Invest. 88(5): 1581-8.
6. Calissano, P., Moore, B.W., and Freisen, A. (1969). Effect of calcium ion on S-100, a protein of the nervous system. Biochemistry. 8: 4318-4328.
7. Carter, L.F., and Rubin, S.A. (1994). The molecular and cellular biology of heart failure. Curr. Opin. Cardiol. 9(3): 264-71.
8. Castets, F., Griffin, W.S.T., Marks, A., and Van Eldik, L.J. (1997). Transcriptional regulation of the human S100 beta gene. Mol. Brain Res. 46: 208-216.
9. Fano, G., Biocca, S., Fulle, S., Mariggio, M.A., Belia, S., and Calissano, P. (1995). The S-100: A protein family in search of a function. Progr. Neurobiol. 46: 71-82.
10. Friend, W., Clapoff, S., Landry, C., Becker, L., O'Hanlon, D., Allore, R., Brown, I., Marks, A., Roder, J., and Dunn, R. (1992). Cell-specific expression of high levels of human S100 beta in transgenic mouse brain is dependent on gene dosage. J. Neurosci. 12(11): 4337-4346.
11. Gidh-Jain, M., Huang, B., Jain, P., Battula, V., and el-Sherif, N. (1995). Reemergence of the fetal pattern of L-type calcium channel gene expression in non infarcted myocardium during left ventricular remodeling. Biochem. Biophys. Res. Commun. 216(3): 892-7.
12. Gottshall, K.R., Becker, K.D., Hunter, J.J., and Chien, K.R. (1996). A genetic based model of cardiac hypertrophy in MLC-ras mice. J. Card. Fail. 2(4 Suppl): S28-34.
13. Haimoto, H., and Kato, K. (1988). S100a (alpha alpha) protein in cardiac muscle. Isolation from human cardiac muscle and ultrastructural localization. Eur. J. Biochem. 171: 409-415.
14. Hanatani, A., Yoshiyama, M., Kim, S., Omura, T., Toda, I., Akioka, K., Teragaki, M., Takeuchi, K., Iwao, H., and Takeda, T. (1995). Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction. J. Mol. Cell. Card. 27(9): 1905-14.
15. Hare, J.M., Keaney, J.F., Jr., Balligand, J.L., Loscalzo, J., Smith, T.W., and Colucci, W.S. (1995). Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs. J. Clin Invest. 95(1): 360-6.
16. Hewett, T.E., Grupp, I.L., Grupp, G., and Robbins, J. (1994). Alpha-skeletal actin is associated with increased contractility in the mouse heart. Circ. Res. 74(4): 740-6.
17. Hu, E., Mueller, E., Oliviero, S., Papaioannou, V.E., Johnson, R., and Spiegelman, B.M. (1994). Targeted disruption of the c-fos gene demonstrates c-fos-dependent and -independent pathways for gene expression stimulated by growth factors or oncogenes. EMBO J. 13(13): 3094-103.
18. Hu, J., and Van Eldik, L.J. (1996). S100 beta induces apoptotic cell death in cultured astrocytes via a nitric oxide-dependent pathway. Biochim. Biophys. Acta. 1313: 229-238.
19. Izumo, S., Lompre, A.M., Matsuoka, R., Koren, G., Schwartz, K., Nadal-Ginard, B., and Mahdavi, V. (1987). Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals. J. Clin. Invest. 79(3): 970-7.
20. Kahn, H.J., Baumal, R., Van Eldik, L.J., Dunn, R.J., and Marks, A. (1991). Immunoreactivity of S100 beta in heart, skeletal muscle, and kidney in chronic lung disease: Possible induction by cAMP. Modern Pathol. 4: 698-701.
21. Kajstura, J., Cheng, W., Reiss, K., Clark, W.A., Sonnenblick, E.H., Krajewski, S., Reed, J.C., Olivetti, G., and Anversa, P. (1996). Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest. 74(1): 86-107.
22. Kanda, T., Nakano, M., Arai, M., Yamamoto, A., Suzuki, T., and Murata, K. (1993). Myocardial atrial natriuretic factor gene expression after coronary ligation in rats. Exp. Clin. Endocrin. 101(3): 173-177.
23. Kannel, W.B., Wolf, P.A., and Garrison, R.J. (1987). Framingham heart Study, 30 year follow-up. NIH pub 87-2703.
24. Kariya, K., Farrance, I.K., and Simpson, P.C. (1993). Transcriptional enhancer factor-1 in cardiac myocytes interacts with an alpha 1-adrenergic- and beta-protein kinase C-inducible element in the rat beta-myosin heavy chain promoter. J. Biol. Chem. 268(35): 26658-62.
25. Kariya, K., Karns, L.R., and Simpson, P.C. (1991). Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene. J. Biol. Chem. 266(16): 10023-6.
26. Kariya, K., Karns, L.R., and Simpson, P.C. (1994). An enhancer core element mediates stimulation of the rat beta-myosin heavy chain promoter by an alpha 1-adrenergic agonist and activated beta-protein kinase C in hypertrophy of cardiac myocytes. J. Biol. Chem. 269(5): 3775-82.
27. Karns, L.R., Kariya, K., and Simpson, P.C. (1995). M-CAT, CArG, and Sp1 elements are required for alpha 1-adrenergic induction of the skeletal alpha-actin promoter during cardiac myocyte hypertrophy. Transcriptional enhancer factor-1 and protein kinase C as conserved transducers of the fetal program in cardiac growth. J. Biol. Chem. 270(1): 410-417.
28. Kato, K., and Kimura, S. (1985). S100a (alpha alpha) protein is mainly located in the heart and striated muscles. Biochim. Biophys. Acta. 842: 146-150.
29. Katz, A.M. (1990). Is heart failure an abnormality of myocardial cell growth? Cardiology. 77(5): 346-56.
30. Kelly, R.A., Balligand, J.L., and Smith, T.W. (1996). Nitric oxide and cardiac function. Circ. Res. 79(3): 363-380.
31. Kligman, D., and Hilt, D.C. (1988). The S100 protein family. TIBS. 13: 437-443.
32. Marks, A., Law, J., Mahony, J.B., and Baumal, R. (1983). The structural conservation of S100 protein during evolution: Analysis by reactivity with a monoclonal antibody. J. Neurochem. 42: 107-112.
33. Matsuoka, H., Nakata, M., Kohno, K., Koga, Y., Nomura, G., Toshima, H., and Imaizumi, T. (1996). Chronic L-arginine administration attenuates cardiac hypertrophy in spontaneously hypertensive rats. Hypertension. 27(1): 14-8.
34. Mercadier, J.J., Lompre, A.M., Due, P., Boheler, K.R., Fraysse, J.B., Wisnewsky, C., Allen, P.D., Komajda, M., and Schwartz, K. (1990). Altered sarcoplasmic reticulum Ca2(+)-ATPase gene expression in the human ventricle during end-stage heart failure. J. Clin. Invest. 85(1): 305-9.
35. Moalic, J.M., Moazami-Goudarzi, K., Thiem, N.V., Delcayre, C., Bercovici, J., Mouas, C., and Swynghedauw, B. (1992). Hormonal induction of c-fos and HSP68 mRNAs on an isolated coronary perfused adult rat heart. Archives Internationales de Physiologie, de Biochimie et de Biophysique. 100(2): 165-170.
36. Moore, B.W. (1965). A soluble protein characteristic of the nervous system. Biochem. Biophys. Res. Commun. 175: 739-744.
37. Moreno, H., Jr., Metze, K., Bento, A.C., Antunes, E., Zatz, R., and de Nucci, G. (1996). Chronic nitric oxide inhibition as a model of hypertensive heart muscle disease. Basic Res Cardiol. 91(3): 248-255.
38. Olivetti, G., Quaini, F., Lagrasta, C., Cigola, E., Ricci, R., Maestri, R., and Anversa, P. (1995). Cellular basis of ventricular remodeling after myocardial infarction in rats. Cardioscience. 6(2): 101-106.
39. Orenstein, T.L., Parker, T.G., Butany, J.W., Goodman, J.M., Dawood, F., Wen, W.H., Wee, L., Martino, T., McLaughlin, P.R., and Liu, P.P. (1995). Favorable left ventricular remodeling following large myocardial infarction by exercise training. Effect on ventricular morphology and gene expression. J. Clin. Invest. 96(2): 858-866.
40. Parker, T.G. (1993). Molecular biology of cardiac growth and hypertrophy. Herz. 18(4): 245-255.
41. Parker, T.G., Packer, S.E., and Schneider, M.D. (1990). Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes. J. Clin. Invest. 85(2): 507-514.
42. Parker, T.G., and Schneider, M.D. (1991). Growth factors, proto-oncogenes, and plasticity of the cardiac phenotype. Ann. Rev. Physiol. 53: 179-200.
43. Penninger, J., Pummerer, C., Liu, P., Neu, N., and Bachmaier, K. (1997). Cellular and molecular mechanisms of murine autoimmune myocarditis. APMIS. 105: 1-13.
44. Persechini, A., Moncrief, N.D., and Kretsinger, R.H. (1989). The EF-hand family of calcium-modulated proteins. TINS. 12: 462-467.
45. Pfeffer, J., Pfeffer, M., Fletcher, P., and Braunwald, E. (1991). Progressive ventricular remodeling in rat with myocardial infarction. Am. J. Physiol. 260:H1: 1406-1414.
46. Pinsky, D.J., Cai, B., Yang, X., Rodriguez, C., Sciacca, R.R., and Cannon, P.J. (1995). The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. J. Clin. Invest. 95(2): 677-685.
47. ++-binding protein S100A1 in human cardiomyopathy. Biochima et Biophysica Acta. 1313: 253-257.
48. Sadoshima, J., Qiu, Z., Morgan, J.P., and Izumo, S. (1995). Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling. Circ. Res. 76(1): 1-15.
49. Sadoshima, J., Takahashi, T., Jahn, L., and Izumo, S. (1992). Roles of mechano-sensitive ion channels, cytoskeleton, and contractile activity in stretch-induced immediate-early gene expression and hypertrophy of cardiac myocytes. Proc. Natl. Acad. Sci. USA. 89(20): 9905-9909.
50. Schulz, R., and Wambolt, R. (1995). Inhibition of nitric oxide synthesis protects the isolated working rabbit heart from ischaemia-reperfusion injury. Cardiovasc Res. 30(3): 432-439.
51. Schwartz, K., Boheler, K.R., de la Bastie, D., Lompre, A.M., and Mercadier, J.J. (1992). Switches in cardiac muscle gene expression as a result of pressure and volume overload. Am. J. Physiol. 262: R364-369.
52. Sheu, F.-S., Azmitia, F.C., Marshak, D.R., Parker, P., and Routtenberg, A. (1994). Glial-derived S100b protein selectively inhibits recombinant beta protein kinase C (PKC) phosphorylation of neuron-specific protein F1/GAP43. Mol. Brain. Res. 21: 62-66.
53. Shindo, T., Ikeda, U., Ohkawa, F., Kawahara, Y., Yokoyama, M., and Shimada, K. (1995). Nitric oxide synthesis in cardiac myocytes and fibroblasts by inflammatory cytokines. Cardiovasc. Res. 29(6): 813-819.
54. Simpson, P., Bishopric, N., Coughlin, S., Karliner, J., Ordahl, C., Starksen, N., Tsao, T., White, N., and Williams, L. (1986). Dual trophic effects of the alpha 1-adrenergic receptor in cultured neonatal rat heart muscle cells. J. Mol. Cell. Card. 18(Suppl 5): 45-58.
55. Soonpaa, M.H., Daud, A.I., Koh, G.Y., Klug, M.G., Kim, K.K., Wang, H., and Field, L.J. (1995). Potential approaches for myocardial regeneration. Ann. N.Y. Acad. Sci. 752: 446-454.
56. Takahashi, K., Isobe, T., Ohtsuki, Y., Akagi, T., Sonobe, H., and Okuyama, T. (1984). Immunohistochemical study on the distribution of alpha and beta subunits of S-100 protein in human neoplasm and normal tissues. Virchows Arch. (Cell Pathol.). 45: 385-396.
57. Tsoporis, J.N., Marks, A., Kahn, H.J., Butany, J.W., Liu, P.P., D., O.H., and Parker, T.G. (1997a). S100b inhibits a1-adrnergic induction of the hypertrophic phenotype in cardiac myocytes. J. Biol. Chem. 272(50): 31915-31921.
58. Tsoporis, J.N., Marks, A., and Parker, T.G. (1997b). The role of nitric oxide and transcriptional enhancer factor-1 in S100b inhibition of norepinephrine-inducible cardiac myocyte gene expression. Can. J. Card. 13(Suppl. C): 97C.
59. Tsoporis, J.N., Marks, A., Kahn, H.J., Butany, J.W., Liu, P.P., O. Hanlon., D., and Parker, T.G. (1997c). Inhibition of norepinephrine-induced cardiac hypertrophy in S100b transgenic mice. Circulation Suppl. I: 117.
60. Waspe, L.E., Ordahl, C.P., and Simpson, P.C. (1990). The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes. J. Clin. Invest. 85(4): 1206-1214.
61. Zimmer, D.B., and Van Eldik, L.J. (1987). Tissue distribution of rat S100 alpha and S100 beta and S100-binding proteins. Am. J. Physiol. 252: C285-289.