Diacylglycerol-induced protection against injury during ischemia and reperfusion in the rat heart: Comparative studies with ischemic preconditioning

International Journal of Cardiology

Volumn 65, Issue 2, 1998, Pages 129-138

  Galiñanes, Manuel ^a   Goss, Martin W ^a   McGill, Caryn J ^a   Hearse, David J ^a   Brooks, Gavin ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Diacylglycerol; Ischemia; Preconditioning; Protein kinase C; Rat heart

Indexed keywords

DIACYLGLYCEROL; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART INJURY; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MEDIATOR RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RAT; TISSUE INJURY;

EID: 0032127931     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(98)00108-9     Document Type: Article

References (35)

1. Lawson C.S., Downey J.M. Preconditioning: state of the art myocardial protection. Cardiovasc Res. 27:1993;542-550.
2. Yellon D.M., Alkhulaifi A.M., Pugsley W.B. Preconditioning the human myocardium. Lancet. 342:1993;276-277.
3. 1 adenosine receptors in rabbit heart. Circulation. 84:1991;350-356.
4. Cave A.C., Collis C.S., Downey J.M., Hearse D.J. Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic, isolated rat heart. Cardiovasc Res. 27:1993;663-668.
5. Li Y., Kloner R.A. The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts. Circulation. 87:1993;1642-1648.
6. 1-adrenergic mechanism. Circ Res. 73:1993;656-670.
7. 1-adrenergic agonists predondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C. Circ Res. 75:1994;576-585.
8. Meldrum D.R., Cleveland J.C., Sheridan B.C., Rowland R.T., Banerjee A., Harken A.D. Cardiac preconditioning with calcium: clinically accessible myocardial protection. J Thorac Cardiovasc Surg. 112:1996;778-786.
9. 2+ as a mediator of ischemic preconditioning. Circ Res. 80:1997;790-799.
10. Downey JM, Cohen MV. Mechanisms of preconditioning: correlates and epiphenomena. In: Marber MM, Yellon DM, editors. Ischaemia: Preconditioning and Adaptation. Oxford, UK: UCL Molecular Pathology Series, BIOS Scientific Publishers Limited; 1996:21-34.
11. Brooks G., Hearse D.J. Role of protein kinase C in ischemic preconditioning: player or spectator? Circ Res. 79:1996;627-630.
12. 1-adrenoceptors in myocardium: functional aspects and transmembrane signalling mechanisms. Physiol Rev. 73:1993;469-487.
13. 1-adrenoceptors: an overview. Pharmacol Rev. 45:1993;147-175.
14. Speechly-Dick M.E., Mocanu M.M., Yellon D.M. Protein kinase C: its role in ischemic preconditioning in the rat. Circ Res. 75:1994;586-590.
15. Mitchell M.B., Meng X., Ao L., Brown J.M., Harken A.H., Banerjee A. Preconditioning of isolated rat heart is mediated by protein kinase C. Circ Res. 76:1995;73-81.
16. Nishizuka Y. Studies and perspectives of protein kinase C. Science. 233:1986;305-312.
17. Hearse D.J., Garlick P.B., Humphrey S.M. Ischemic contracture of the myocardium: mechanisms and prevention. Am J Cardiol. 39:1977;986-993.
18. Ganote C.E., Seabra-Gomes R., Nayler W.G., Jennings R.B. Irreversible myocardial injury in anoxic perfused rat hearts. Am J Pathol. 80:1975;419-450.
19. 1 receptor mediated protection of the globally ischemic isolated rat heart. J Mol Cell Cardiol. 22:1990;39-47.
20. Galiñanes M., Hearse D.J. Species differences in susceptability to ischemic injury and responsiveness to myocardial protection. Cardioscience. 1:1990;127-143.
21. Kolocassides K.G., Galiñanes M., Hearse D.J. Preconditioning accelerates contracture and ATP depletion in blood-perfused rat hearts. Am J Physiol. 269:1995;H1415-H1420.
22. Galiñanes M., Argano V., Hearse D.J. Can ischemic preconditioning ensure optimal myocardial protection when delivery of cardioplegia is impaired? Circulation. 92(II):1995;389-394.
23. Kolocassides K.G., Galiñanes M., Hearse D.J. Dichotomy of ischemic preconditioning: improved postischemic contractile function despite intensification of ischemic contracture. Circulation. 93:1996;1725-1733.
24. Kolocassides K.G., Seymour A.M.L., Galiñanes M., Hearse D.J. Paradoxical effect of ischemic preconditioning on ischemic contracture? NMR studies of energy metabolism and intracellular pH in the rat hearts. J Mol Cell Cardiol. 28:1996;1045-1057.
25. Brooks G., Goss M.W., East J.A., Hart I.R. Growth of melanocytic cells is associated with down-regulation of protein kinase C α, δ and ε isoforms. J Biol Chem. 268:1993;23868-23875.
26. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
27. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 258:1992;607-614.
28. Brooks G, Goss MW, Rozengurt E, Galiñanes M. Phorbol ester, but not ischemic preconditioning, activates protein kinase D in the rat heart. J Mol Cell Cardiol 1998 (in press).
29. Kolocassides K.G., Galiñanes M., Hearse D.J. The protein kinase C inhibitor polimyxin B blocks the functional protection of preconditioning but not the acceleration of ischaemic contracture. J Mol Cell Cardiol. 27:1995;A155.
30. 1-receptor-induced activation of protein kinase C in acute myocardial ischemia: mechanisms for sensitization of the adenylyl cyclase system. Circ Res. 70:1992;1304-1312.
31. Liu Y., Ytrehus K., Downey J.M. Evidence that translocation of protein kinase C is a key event during ischemic preconditioning of rabbit myocardium. J Mol Cell Cardiol. 26:1994;661-668.
32. Ytrehus K., Liu Y., Downey J.M. Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol. 266:1994;H1145-H1152.
33. McGill CJ, Brooks G. Expression and regulation of 80K/MARCKS, a major substrate of protein kinase C, in the developing rat heart. Cardiovasc Res 1998 (in press).
34. Chen W., Wetsel W., Steenbergen C., Murphy E. Effect of ischemic preconditioning and PKC activation on acidification during ischemia in rat heart. J Mol Cell Cardiol. 28:1966;871-880.
35. Ping P., Zhang J., Qiu Y., Tang X.-L., Manchikalapudi S., Cao X., Bolli R. Ischemic preconditioning induces selective translocation of protein kinase C isoforms ε and η in the heart of conscious rabbits without subcellular redistribution of total protein kinase C activity. Circ Res. 81:1997;404-414.