Paradoxical effect of ischemic preconditioning on ischemic contracture? NMR studies of energy metabolism and intracellular pH in the rat heart

Journal of Molecular and Cellular Cardiology

Volumn 28, Issue 5, 1996, Pages 1045-1057

  Kolocassides, Kyriacos G ^a   Seymour, Anne Marie L ^b   Galiñanes, Manuel ^a   Hearse, David J ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Adenosine triphosphate; Cardioplegia; Intracellular pH; Ischemic contracture; Ischemic preconditioning; Phosphocreatine

Indexed keywords

ADENOSINE TRIPHOSPHATE;

ACIDOSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOPLEGIA; CELL PH; CONDITIONING; CONTROLLED STUDY; ENERGY METABOLISM; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; ISOLATED HEART; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; VOLKMANN CONTRACTURE;

EID: 0029938708     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1996.0097     Document Type: Article

References (35)

1. ALLARD MF, EMANUEL PG, RUSSELL JA, BISHOP SP, DIGERNESS SB, ANDERSON PG, 1994. Preischemic glycogen reduction or inhibition improves postischemic recovery of hypertrophied hearts. Am J Physiol 267 (Heart Circ Physiol 36): H66-H74.
2. ASIMAKIS GK, INNERS-MCBRIDE K, MEDELLIN G, CONTI VR, 1992. Ischemic preconditioning attenuates acidosis and postischemic dysfunction in isolated rat heart. Am J Physiol 263: H887-H894.
3. AXFORD TC, DEARANI JA, KHAIT I et al., 1992. Electrodederived myocardial pH measurements reflect intracellular myocardial metabolism assessed by phosphorus 31-nuclear magnetic resonance spectroscopy during normothermic ischemia. J Thorac Cardiovasc Surg 103: 902-907.
4. DE ALBUQUERQUE CP, WEISS GG, 1994. Importance of metabolic inhibition and cellular pH in mediating preconditioning contractile and metabolic effects in rat hearts. Circ Res 74: 139-150.
5. DENNIS SC, GEVERS W, OPIE LH, 1991. Protons in ischemia: where do they come from; where do they go to? J Mol Cell Cardiol 23: 1077-1086.
6. EISNER DA, SMITH GL, O'NEILL SC, 1993. The effects of lactic acid production on contraction and intracellular pH during hypoxia in cardiac muscle. Basic Res Cardiol 88: 421-429.
7. GARLICK PB, RADDA GK, SEELEY PJ, 1990. Studies of acidosis in the ischemic heart by phosphorus nuclear magnetic resonance. Biochem J 184: 547-554.
8. GEISBUHLER TP, ROVETTO MJ, 1990. Lactate does not enhance anoxia/reoxygenation damage in adult rat cardiac myocytes. J Mol Cell Cardiol 22: 1325-1335.
9. HEARSE DJ, GARLICK PB, HUMPHREY SM, 1977. Ischemic contracture of the myocardium: Mechanisms and prevention. Am J Cardiol 39: 986-993.
10. KIDA M, FUJIWARA H, ISHIDA M et al., 1991. Ischemic preconditioning preserves creatine phosphate and intracellular pH. Circulation 84: 2495-2503.
11. 31P-NMR study of isolated rat hearts. Am J Physiol 261: H469-H478.
12. KLÉBER AG, YAN G-X, 1992. Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle. Circ Res 71: 460-470.
13. KOLOCASSIDES KG, GALIÑANES M, HEARSE DJ, 1994a. Ischemic preconditioning, cardioplegia or both? J Mol Cell Cardiol 26: 1411-1414.
14. KOLOCASSIDES KG, GALIÑANES M, HEARSE DJ, 1994b. Opposing facets of ischemic preconditioning? Acceleration of ischemic contracture with reduction of post-ischemic contractile dysfunction. (Abstract) Circulation 90: I-478.
15. KUPRIYANOV W, KAKOMKIN VL, STEINSCHNEIDER A, SEVERINA M, KAPELKO VI, RUUGE EK, SAKS VA, 1988. Relationships between pre-ischemic ATP and glycogen content and post-ischemic recovery of rat heart. J Mol Cell Cardiol 20: 1151-1162.
16. LASLEY DR, ANDERSON GM, MENTZER RM, 1993. Ischemic and hypoxic preconditioning enhance postischemic recovery of function in the rat heart. Cardiovasc Res 27: 565-570.
17. LAWSON CS, DOWNEY JM, 1993. Preconditioning: state of the art myocardial protection. Cardiovasc Res 27: 542-550.
18. LIPASTI JA, NEVALAINEN TJ, ALANEN KA, TOLVENEN MA, 1984. Anaerobic glycolysis and the development of ischaemic contracture in isolated rat heart. Cardiovasc Res 18: 145-148.
19. MOHABIR R, LEE H-C, KURZ RW, CLUSIN WT, 1991. Effects of ischemia and hypercarbic acidosis on myocyte calcium transients, contraction and pHi in perfused rabbit hearts. Circ Res 69: 1525-1537.
20. MOOLENAAR WH, TERTOOLEN LGJ, DE LAAT SW, 1984. Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH. Nature 312: 371-374.
21. MURRY CE, RICHARD VJ, REIMER KA, JENNINGS RB, 1990. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res 66: 913-931.
22. NEELY JR, GROTYOHANN LW, 1984. Role of glycolytic products in damage to ischemic myocardium: dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts. Circ Res 55: 816-824.
23. NEELY JR, MORGAN HE, 1974. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. An Rev Physiol 36: 413-459.
24. OWEN P, DENNIS S, OPIE LH, 1990. Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts. Circ Res 66: 344-354.
25. PIPER HM, NOLL T, SIEGMUND B, 1994. Mitochondrial function in the oxygen depleted and reoxygenated myocardial cell. Cardiovasc Res 28: 1-15.
26. ROVETTO MJ, LAMBERTON WF, NEELY JR, 1975. Mechanisms of glycolytic inhibition in ischemic rat hearts. Circ Res 37: 742-751.
27. SEYMOUR A-ML, ELDAR H, RADDA GK, 1990. Hyperthyroidism results in increased glycolytic capacity in the rat. A 31P-NMR study. Biochim Biophys Acta 1055: 107-116.
28. SINK JD, CURRIE WD, PELLOM GL, HILL RC, CHITWOOD WJ, WECHSLER AS, 1980. Correlation of mitochondrial function and ischemic contracture. J Thorac Cardiovasc Surg 79: 570-578.
29. STEENBERGEN C, PERLMAN ME, LONDON RE, MURPHY E, 1993. Mechanism ofpreconditioning. Ionic alterations. Circ Res 72: 112-125.
30. 2+ overload and impairs function in anoxic rat heart. J Mol Cell Cardiol 22: 57-72.
31. VENTURA-CLAPIER R, VEKSLER V, 1994. Myocardial ischemic contracture. Metabolites affect rigor tension development and stiffness. Circ Res 74: 920-929.
32. VOLOVSEK A, SUBRAMANIAN R, REBOUSSIN D, 1992. Effects of duration of ischemia during preconditioning on mechanical function, enzyme release and energy production in the isolated working rat heart. J Mol Cell Cardiol 24: 1011-1019.
33. WOLFE CL, SIEVERS RE, VISSEREN FLT, DONNELLY TJ, 1993. Loss of myocardial protection after preconditioning correlates with the time course of glycogen recovery within the preconditioned segment. Circulation 87: 881-892.
34. YELLON DM, ALKHULAIFI AM, PUGSLEY WB, 1993. Preconditioning the human myocardium. Lancet 342: 276-277.
35. YTREHUS K, LIU Y, DOWNEY JM, 1994. Preconditioning protects the ischemic rabbit heart by protein kinase C activation. Am J Physiol 266: H1145-H1152.