Bacterial O6-methylguanine-DNA methyltransferase reduces N-methyl-N'- nitro-N-nitrosoguanidine induction of plasminogen activator in Mer- human glioblastoma A1235 cell line

Mutation Research - DNA Repair

Volumn 408, Issue 1, 1998, Pages 47-54

  Lončarek, Jadranka ^b   Sorić, Jasna ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b NONE

Author keywords

ada alkB operon; Mer phenotype; O6 Methylguanine DNA methyltransferase; Plasminogen activator

Indexed keywords

DNA METHYLTRANSFERASE; METHYLNITRONITROSOGUANIDINE; PLASMINOGEN ACTIVATOR;

ALKYLATION; ARTICLE; BACTERIAL MEMBRANE; CELL KILLING; CELL SURVIVAL; CELL TRANSFORMATION; CYTOTOXICITY; DNA ADDUCT; DNA DAMAGE; DNA REPAIR; GLIOBLASTOMA; HUMAN; HUMAN CELL; MUTAGENICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ADA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

EID: 0032126113     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(98)00019-6     Document Type: Article

References (35)

1. [1] B. Stauss, D. Scudiero, E. Henderson, The nature of the alkylation lesion in mammalian cells, in: P.C. Hanawalt, R.B. Setlow (Eds.), Molecular Mechanisms for Repair of DNA, Part A, Plenum, New York, 1975, pp. 13-24.
2. [2] P. Karran, T. Lindahl, Cellular defence mechanisms against alkylating agents, Cancer Surv. 4 (1985) 583-599.
3. 6-methylguanine from DNA by mammalian cell extracts, Biochem. Biophys. Res. Commun. 84 (1978) 166-173.
4. 6-methylguanine produced by N-methyl-N-nitro-N-nitrosoguanidine in mouse and human cells, Carcinogenesis 5 (1984) 593-600.
5. [5] B. Demple, P. Karran, Death of an enzyme: suicide repair of DNA, Trends Biol. Sci. 8 (1983) 137-139.
6. [6] B. Demple, B. Sedgvick, P. Robins, N. Totty, M.D. Waterfield, T. Lindahl, Active site and complete sequence for the suicidal methyltransferase that counters alkylation mutagenesis, Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 2688-2692.
7. 6-methylguanine-DNA methyltransferase, J. Biol. Chem. 260 (1985) 7281-7288.
8. [8] T. Lindahl, B. Sedgwick, M. Sekiguchi, Y. Nakabeppu, Regulation and expression of the adaptive response to alkylating agents, Annu. Rev. Biochem. 57 (1988) 133-157.
9. [9] R.S. Day III, C.H.J. Ziolkowski, D.A. Scudiero, S.A. Meyer, M.R. Mattern, Human tumor cell strains defective in the repair of alkylation damage, Carcinogenesis 1 (1980) 21-31.
10. [10] B. Brdar, J. Sorić, Reactivation of alkylation damaged Adenovirus 3 by cell cultures derived from human tumors. Biological characterisation of human tumors, in: W. Davis, C. Maltoni, S. Tanennebrger (Eds.), The Control of Tumour Growth and its Biological Bases, Akademie Verlag, Berlin, 1983, pp. 413-417.
11. [11] D.A. Scudiero, S.A. Meyer, B.E. Clatterbuck, M.R. Mattern, C.H.J. Ziolkowski, R.S. Day III, Relationship of DNA repair phenotypes of human fibroblast and tumor strains to killing by N-methyl-N-nitro-N-nitrosoguanidine, Cancer Res. 44 (1984) 961-969.
12. [12] L. Samson, B. Derfler, E.A. Waldstein, Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes, Proc. Natl. Acad. Sci. U.S.A. 83 (1986) 5607-5610.
13. 6-methylguanine-DNA methyltransferase (MGMT) cDNA in chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents, Carcinogenesis 12 (1991) 1857-1867.
14. 6-methylguanine-DNA methyltransferase in a DNA excision repair-deficient chinese hamster ovary cell line and its response to certain alkylating agents, Cancer Res. 52 (1992) 32-35.
15. 6-alkyguanine-DNA alkyltransferase, Science 259 (1993) 219-222.
16. [16] J.C. Unkeless, A. Tobia, L. Osowski, J.P. Qugley, D.B. Rifkin, E. Reich, An enzymatic function associated with transformation of fibroblasts by oncogenic viruses: I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses, J. Exp. Med. 137 (1973) 85-111.
17. [17] J. Sorić, B. Brdar, Synthesis of plasminogen activator by cell cultures of human brain tumours, Period. Biol. 82 (1980) 217-221.
18. [18] K. Dano, P.A. Andreasen, J. Grondahl-Hansen, P. Kristensen, L.S. Nielsen, L. Skriver, Plasminogen activators, tissue degradation, and cancer, Adv. Cancer Res. 44 (1985) 139-266.
19. [19] B. Brdar, Induction of plasminogen activator by alkylating agents in repair defective human glioblastoma cell strain, Cancer Res. 46 (1986) 2282-2284.
20. - human tumour cell strains, Carcinogenesis 12 (1988) 2191-2195.
21. - human tumor cell line, Mutat. Res. 314 (1994) 99-113.
22. [22] J. Sambrook, E.F. Fritsch, T. Maniatis, Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 1989.
23. [23] P. Chomczynski, N. Sacchi, Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, Anal. Biochem. 162 (1987) 156-159.
24. [24] P.D. Lawley, C.J. Thatcher, Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine, Biochem. J. 116 (1970) 693-707.
25. [25] O. Saksella, Radial caseinolylis in agarose: a simple method for detection of plasminogen activator in the presence of inhibitory substances and serum, Anal. Biochem. 111 (1981) 276-282.
26. [26] F. Colbere-Garapin, F. Horodniceanu, P. Kourilsky, A.-C. Garapin, A new dominant hybrid selective marker for higher eukaryotic cells, J. Mol. Biol. 150 (1981) 1-14.
27. 6-methylguanine residues in DNA, Nature 280 (1979) 76-78.
28. 6-methylguanine DNA methyltransferase in human tumor and corresponding normal tissue, Cancer Detect. Prevent. 20 (1996) 130-136.
29. 6-methylguanine DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs, Int. J. Cancer 65 (1996) 506-512.
30. [30] E.L. Wilson, M.L.B. Becker, E.G. Hoal, E.B. Dowdle, Molecular species of plasminogen activators secreted by normal and neoplastic human cells, Cancer Res. 40 (1980) 933-938.
31. [31] J. Sorić, E. Korkut, B. Brdar, Enhanced survival of alkylation damaged Adenovirus 3 on HeLa cells treated by mechlorethamine, Period. Biol. 84 (1982) 339-342.
32. [32] R. Miskin, R. Ben-Ishai, Induction of plasminogen activator by UV light in normal and Xeroderma pigmentosum fibroblasts, Proc. Natl. Acad. Sci. U.S.A. 78 (1981) 6236-6240.
33. [33] D.B. Rifkin, L.P. Beal, E. Reich, Macromolecular determinants of plasminogen activator synthesis, in: Proteases and Biological Control, Cold Spring Harbor Laboratory, 1975, pp. 841-847.
34. [34] P.H.A. Quax, R.T.J. van Leeuven, H.W. Verspaget, J.H. Verheijen, Protein and messenger RNA levels of plasminogen activators and inhibitors analysed in 22 human tumor cell lines, Cancer Res. 50 (1990) 1488-1494.
35. [35] G. Eisenbrand, S. Lauck-Birkel, W.C. Tang, An approach towards more selective anticancer agents, Synthesis 10 (1996) 1246-1258.