Enhanced expression of GM-CSF in differentiating eosinophils of atopic and atopic asthmatic subjects

American Journal of Respiratory Cell and Molecular Biology

Volumn 19, Issue 1, 1998, Pages 55-62

  Gauvreau, Gail M ^b   O'Byrne, Paul M ^b   Moqbel, Redwan ^b   Velazquez, Juan ^b   Watson, Rick M ^b   Howie, Karen J ^b   Denburg, Judah A ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 5;

ARTICLE; ASTHMA; BIOSYNTHESIS; BLOOD; CELL CULTURE; CELL DIFFERENTIATION; CLONOGENIC ASSAY; COMPARATIVE STUDY; CYTOLOGY; EOSINOPHIL; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; IMMEDIATE TYPE HYPERSENSITIVITY; IMMUNOLOGY; INHALATION TEST; LEUKOCYTE COUNT; MALE;

ALLERGENS; ASTHMA; BRONCHIAL PROVOCATION TESTS; CELL DIFFERENTIATION; CELLS, CULTURED; COLONY-FORMING UNITS ASSAY; EOSINOPHILS; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; HYPERSENSITIVITY, IMMEDIATE; INTERLEUKIN-5; LEUKOCYTE COUNT; MALE;

EID: 0032109492     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.19.1.2871     Document Type: Article

References (41)

1. Weller, P. F. 1994. Eosinophils: structure and functions. Curr. Opin. Immunol. 6:85-90.
2. Denburg, J. A., S. J. Ackerman, G. J. Gleich, S. Telizyn, and J. Bienenstock. 1985. Heterogeneity of human peripheral blood eosinophil-type colonies: evidence for a common basophil-eosinophil progenitor. Blood 66:312-318.
3. Denburg, J. A., S. Telizyn, A. Belda, J. Dolovich, and J. Bienenstock. 1985. Increased numbers of circulating basophil progenitors in atopic patients. J. Allergy Clin. Immunol. 76:466-172.
4. Otsuka, H., J. Dolovich, A. D. Befus, S. Telizyn, J. Bienenstock, and J. A. Denburg. 1986. Basophilic cell progenitors, nasal metachromatic cells, and peripheral blood basophils in ragweed-allergic patients. J. Allergy Clin. Immunol. 78:365-371.
5. Gibson, P. G., J. Dolovich, A. Girgis-Gabardo, M. M. Morris, M. Anderson, F. E. Hargreave, and J. A. Denburg. 1990. The inflammatory response in asthma exacerbation: changes in circulating eosinophils, basophils and their progenitors. Clin. Exp. Allergy 20:661-668.
6. Gibson, P. G., P. J. Manning, P. M. O'Byrne, A. Girgis-Gabardo, J. Dolovich, J. A. Denburg, and F. E. Hargreave. 1991. Allergen-induced asthmatic responses: relationship between increases in airway responsiveness and increases in circulating eosinophils, basophils, and their progenitors. Am. Rev. Respir. Dis. 143:331-335.
7. Clutterbuck, E. J., and C. J. Sanderson. 1990. Regulation of human eosinophil precursor production by cytokines: a comparison of recombinant human interleukin-1 (rhIL-1), rhIL-3, rhIL-5, rhIL-6, and rh granulocyte-macrophage colony stimulating factor. Blood 75:1774-1779.
8. Desreumaux, O., A. Janin, J. F. Colombel, L. Prin, J, Plumas, D. Emiliee, G. Torpier, A. Capron, and M. Capron. 1992. Interleukin-5 messenger RNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease. J. Exp. Med. 175:293-296.
9. Kita, H., T. Ohnishi, Y. Okubo, D. Weiler, J. S. Abrams, and G. J. Gleich. 1991. Granulocyte/macrophage colony-stimulating factor and interleukin-3 release from human peripheral blood eosinophils and neutrophils. J. Exp. Med. 174:745-748.
10. Moqbel, R., Q. Hamid, S. Ying, J. Barkans, A. Hartnell, A. Tsicopoulos, A. J. Wardlaw, and A. B. Kay. 1991. Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony-stimulating factor in activated human eosinophils. J. Exp. Med. 174:749-752.
11. Broide, D. H., M. M. Paine, and G. S. Firestein. 1992. Eosinophils express interleukin-5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J. Clin. Invest. 90:1414-1424.
12. Ohno, I., R. Lea, S. Finotto, J. Marshall, J. Denburg, J. Dolovich, J. Gauldie, and M. Jordana. 1991. Granulocyte/macrophage colony-stimulating factor (GM-CSF) gene expression by eosinophils in nasal polyposis. Am. J. Respir. Cell Mol. Biol. 5:505-510.
13. Dater, I., and C. Bachert. 1996. Localization of interleukin-5 (IL-5) in RNA in eosinophils of nasal polyps by in situ hybridization. J. Allergy Clin. Immunol. 97:276A. (Abstr.)
14. Hamilos, D. L., D. Y. M. Leung, R. Wood, L. Cunningham, D. K. Bean, Z. Yasruel, E. Schotman, and Q. Hamid. 1995. Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis. J. Allergy Clin. Immunol. 96:537-544.
15. Otsuka, H., J. Dolovich, M. Richardson, J. Bienenstock, and J. A. Denburg. 1987. Metachromatic cell progenitors and specific growth and differentiation factors in human nasal mucosa and polyps. Am. Rev. Respir. Dis. 136: 710-717.
16. Denburg, J. A., M. Jordana, C. Vancheri, J. Gauldie, D. Harnish, T. Ohtoshi, T. Tsuda, P. Gibson, J. Ruhno, J. Bienenstock, F. E. Hargreave, and J. Dolovich. 1989. Locally derived hemopoietic cytokines for human basophils, mast cells and eosinophils in respiratory disease. In Mast Cell and Basophil Differentiation and Function in Health and Disease. S. J. Galli and K. F. Austen, editors. Raven Press, New York. 59-69.14.
17. Cockcroft, D. M. 1985. Measure of airway responsiveness to inhaled histamine or methacholine: method of continuous aerosol generation and tidal breathing inhalation. In Airway Responsiveness: Measurement and Interpretation. F. E. Hargreave and A. J. Woolcock, editors. Astra Pharmaceuticals Canada Ltd., Mississauga, Ontario. 22-28.
18. O'Byrne, P. M., J. Dolovich, and F. E. Hargreave. 1987. Late asthmatic response. Am. Rev. Respir. Dis. 136:740-756.
19. Cockcroft, D. W., K. Y. Murdock, J. Kirby, and F. E. Hargreave. 1987. Prediction of airway responsiveness lo allergen from skin sensitivity to allergen and airway responsiveness to histamine. Am. Rev. Respir. Dis. 135:264-267.
20. Girgis-Gabardo, A., N. Kanai, J. A. Denburg, F. E. Hargreave, M. Jordana, and J. Dolovich. 1994. Immunocytochemical detection of granulocyte-macrophage colony-stimulating factor and eosinophil cationic protein in sputum cells. J. Allergy Clin. Immunol. 93:945-947.
21. Saito, H., T. Hayakawa, H. Mita, K. Akiyatna, and T. Shida. 1993. Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells. EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. Int. Arch. Allergy Immunol. 100:240-247.
22. Vancheri, C., J. Gauldie, J. Bienenstock, O. Cox, R. Scichitano, A. Stanisz, and M. Jordana. 1989. Human lung fibroblast-derived GM-CSF mediates eosinophil survival. Am. J. Respir. Cell Mol. Biol. 1:289-295.
23. Yamaguchi, Y., Y. Hayashi, Y. Sugama, Y. Miura, T. Kasahara, S. Kitamura, M. Torisu, S. Mita, A. Tominaga, K. Takatsu, and T. Suda. 1988. Highly purified interleukin-5 (IL-5) stimulates eosinophil function and prolongs in vitro survival: IL-5 as an eosinophil chemotactic factor. J. Exp. Med. 167:1737-1742.
24. Yamaguchi, Y., T. Suda, J. Suda, M. Eguchi, Y. Miura, N. Harada, A. Tominaga, and K. Takatsu. 1988. Purified interleukin-5 supports the terminal differentiation and proliferation of murine eosinophil precursors. J. Exp. Med. 167:43-56.
25. Rothenberg, M. E., W. F. Owen, Jr., D. S. Silberstein, J. Woods, R. J. Soberman, K. F Austen, and R. L. Stevens. 1988. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin-3. J. Clin. Invest. 81:1986-1992.
26. Walker, C., J. C. Virchow, Jr., P. L. B. Bruijnzeel, and K. Blaser. 1991. T-cell subsets and their soluble products regulate eosinophilia in allergic and non-allergic asthma. J. Immunol. 146:1829-1835.
27. Simon, H.-U., and K. Blaser. 1995. Inhibition of programmed eosinophil death: a key pathogenic event for eosinophilia? Immunol. Today 16:53-55.
28. Yamaguchi, Y. L., T. Suda, S. Ohta, K. Tominaga, Y. Miura, and T. Kasahara. 1991. Analysis of the survival of mature human eosinophils: interleukin-5 prevents apoptosis in mature human eosinophils. Blood 78:2542-2547.
29. Simon, H.-U., S. Yousefi, and K. Blaser. 1995. Tyrosine physophorylation regulates activation and inhibition of apoptosis in human eosinophils and neutrophils. Int. Arch. Allergy Immunol. 107:338-339.
30. Yousefi, S., D. C. Hoessli, K. Blaser, G. B. Mills, and H.-U. Simon. 1996. Requirement of lyn and syk tyrosine kinases for the prevention of apoptosis by cytokines in human eosinophils. J. Exp. Med. 183:1407-1414.
31. Cousins, D. J., D. Z. Staynov, and T. H. Lee. 1994. Regulation of interleukin-5 and granulocyte-macrophage colony-stimulating factor expression. Am. J. Respir. Crit. Care Med. 150:S50-S53.
32. Haynesworth, S. E., M. A. Baber, and A. I. Caplan. 1996. Cytokine expression hy human marrow-derived mesenchymal progenitor cells in vitro: effects of dexamethasone and IL-1α. J. Cell. Physiol. 166:585-592.
33. Ohnishi, M., J. Ruhno, J. Bienenstock, R. Milner, J. Dolovich, and J. A. Denburg. 1988. Human nasal polyp epithelial basophil/mast cell and eosinophil colony-stimulating activity: the effect is T-cell dependent. Am. Rev. Respir. Dis. 138:560-564.
34. Ohnishi, M., J. Ruhno, J. Bienenstock, J. Dolovich, and J. A. Denburg. 1989. Hemopoietic growth factor production by human nasal polyp epithelial scrapings: kinetics, cell source and relationship to clinical status. J. Allergy Clin. Immunol. 87:365-371.
35. Ohtoshi, T., T. Tsuda, C. Vancheri, J. S. Abrams, J. Gauldie, J. Dolovich, J. A. Denburg, and M. Jordana. 1991. Human upper airway epithelial cell-derived granulocyte-macrophage colony-stimulating factor induces histamine-containing cell differentiation of human progenitor cells. Int. Arch. Allergy Appl. Immunol. 95:376-384.
36. Lamas, A. M., G. V. Marcotte, and R. P. Schleimer. 1989. Human endothelial cells prolong eosinophil survival: regulation hy cytokines and glucocorticoids. J. Immunol. 142:3978-3984.
37. Jordana, M., C. Vancheri, T. Ohtoshi, D. Harnish, J. Gauldie, J. Dolovich, and J. Denburg. 1989. Hemopoietic function of the microenvironment in chronic airway inflammation. Agents Actions 28(Suppl.):85-95.
38. Winter, J. N., H. M. Lazarus, A. Rademaker, M. Villa, C. Mangan, M. Tallman, L. Jahnke, L. Gordon, S. Newman, K. Byrd, B. W. Cooper, N. Horvath, E. Crum, E. A. Stadtmauer, E. Conklin, A. Bauman, J. Martin, C. Goolsby, S. L. Gerson, J. Bender, and M. O'Gorman. 1996. Phase I/II study of eomhined granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor administration for the mobilization of hematopoietic progenitor cells. J. Clin. Oncol. 14:277-286.
39. Sehmi, R., K. Howie, D. R. Sutherland, W. Schragge, P. M. O'Byrne, and J. A. Denburg. 1996. Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects. Am. J. Respir. Cell Mol. Biol. 15:645-654.
40. Sehmi, R., L. J. Wood, R. M. Watson, P. M. O'Byrne, and J. A. Denburg. 1997. Increased expression of IL-5 receptor alpha-subunit on hone marrow-derived CD34+ progenitors following allergen challenge in dual responder asthmatics. J. Clin. Invest. 100:2466-2475.
41. Inman, M. D., J. A. Denburg, R. Ellis, M. Dahlback, and P. M. O'Byrne. 1996. Allergen-induced increase in bone marrow progenitors in airway hyperresponsive dogs: regulation hy a serum hemopoietic factor. Am. J. Respir. Cell Mol. Biol. 15:305-311.