메뉴 건너뛰기




Volumn 18, Issue 2, 1998, Pages 162-170

Accelerated changes (inflection points) in levels of serum immune activation markers and CD4+ and CD8+ T cells prior to AIDS onset

Author keywords

AIDS; CD4+; CD8+ T cells; Inflection points; Neopterin; 2 Microglobulin

Indexed keywords

BETA 2 MICROGLOBULIN; CD4 ANTIGEN; CD8 ANTIGEN; NEOPTERIN;

EID: 0032104043     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199806010-00008     Document Type: Article
Times cited : (13)

References (47)
  • 1
    • 0027692154 scopus 로고
    • Multifactorial nature of human immunodeficiency virus disease: Implications for therapy
    • Fauci AS. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 1993;262:1011-18.
    • (1993) Science , vol.262 , pp. 1011-1018
    • Fauci, A.S.1
  • 2
    • 0025069873 scopus 로고
    • The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1
    • Fahey JL, Taylor JMG, Detels R, et al. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N Engl J Med 1990;322:166-72.
    • (1990) N Engl J Med , vol.322 , pp. 166-172
    • Fahey, J.L.1    Taylor, J.M.G.2    Detels, R.3
  • 3
    • 0025100974 scopus 로고
    • AIDS as immune system activation. II. The panergic amnesia hypothesis
    • Ascher MS, Sheppard HW. AIDS as immune system activation. II. The panergic amnesia hypothesis. J Acquir Immune Defic Syndr 1990;3:177-91.
    • (1990) J Acquir Immune Defic Syndr , vol.3 , pp. 177-191
    • Ascher, M.S.1    Sheppard, H.W.2
  • 4
    • 0028158321 scopus 로고
    • Markers predicting progression of human immunodeficiency virus-related disease
    • Tsoukas CM, Bernard NF. Markers predicting progression of human immunodeficiency virus-related disease. Clin Microbiol Rev 1994;7:14-28.
    • (1994) Clin Microbiol Rev , vol.7 , pp. 14-28
    • Tsoukas, C.M.1    Bernard, N.F.2
  • 5
    • 0026687983 scopus 로고
    • Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific
    • Kramer A, Biggar RA, Hampl H, Fuchs D, Goedert JJ. Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. Am J Epidemiol 1992;136:71-80.
    • (1992) Am J Epidemiol , vol.136 , pp. 71-80
    • Kramer, A.1    Biggar, R.A.2    Hampl, H.3    Fuchs, D.4    Goedert, J.J.5
  • 6
    • 85012474693 scopus 로고
    • The immunopathogenesis of human immunodeficiency virus infection
    • Pantaleo G, Graziosi C, Fauci A. The immunopathogenesis of human immunodeficiency virus infection. N Engl J Med 1993;328: 327-35.
    • (1993) N Engl J Med , vol.328 , pp. 327-335
    • Pantaleo, G.1    Graziosi, C.2    Fauci, A.3
  • 7
    • 0029805203 scopus 로고    scopus 로고
    • Host factors and the pathogenesis of HIV-induced disease
    • Fauci AS. Host factors and the pathogenesis of HIV-induced disease. Nature 1996;384:529-34.
    • (1996) Nature , vol.384 , pp. 529-534
    • Fauci, A.S.1
  • 9
    • 0023865054 scopus 로고
    • Seropositivity for HIV and the development of AIDS with AIDS related condition: Three year follow up of the San Francisco General Hospital cohort
    • Moss AR, Bacchetti P, Osmand D, et al. Seropositivity for HIV and the development of AIDS with AIDS related condition: three year follow up of the San Francisco General Hospital cohort. BMJ 1988;296:745-50.
    • (1988) BMJ , vol.296 , pp. 745-750
    • Moss, A.R.1    Bacchetti, P.2    Osmand, D.3
  • 10
    • 0025239026 scopus 로고
    • β2-microglobulin level increases in HIV infection: Relation to seroconversion. CD4 T-cell fall and prognosis
    • Hofmann B, Wang Y, Cumberland WG, Detels R, Bozorgmehri M, Fahey JL. β2-microglobulin level increases in HIV infection: relation to seroconversion. CD4 T-cell fall and prognosis. AIDS 1990;4:207-14.
    • (1990) AIDS , vol.4 , pp. 207-214
    • Hofmann, B.1    Wang, Y.2    Cumberland, W.G.3    Detels, R.4    Bozorgmehri, M.5    Fahey, J.L.6
  • 11
    • 0024385471 scopus 로고
    • Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection
    • Fuchs D, Spira TJ, Hausen A, et al. Neopterin as a predictive marker for disease progression in human immunodeficiency virus type 1 infection. Clin Chem 1989;35:1746-9.
    • (1989) Clin Chem , vol.35 , pp. 1746-1749
    • Fuchs, D.1    Spira, T.J.2    Hausen, A.3
  • 12
    • 0024596777 scopus 로고
    • Serum neopterin changes in HIV-infected subjects; indicator of significant pathology, CD4 T cell change, and the development of AIDS
    • Melmed RN, Taylor JM, Detels R, Bozorgmehri M, Fahey JL. Serum neopterin changes in HIV-infected subjects; indicator of significant pathology, CD4 T cell change, and the development of AIDS. J Acquir Immune Defic Syndr 1989;2:70-6.
    • (1989) J Acquir Immune Defic Syndr , vol.2 , pp. 70-76
    • Melmed, R.N.1    Taylor, J.M.2    Detels, R.3    Bozorgmehri, M.4    Fahey, J.L.5
  • 14
    • 0031057541 scopus 로고    scopus 로고
    • Early levels of CD4, neopterin and β2-microglobulin indicate further disease progression
    • Shi M, Taylor JMG, Fahey JL, et al. Early levels of CD4, neopterin and β2-microglobulin indicate further disease progression. J Clin Immunol 1997;17:43-52.
    • (1997) J Clin Immunol , vol.17 , pp. 43-52
    • Shi, M.1    Taylor, J.M.G.2    Fahey, J.L.3
  • 15
    • 0028131190 scopus 로고
    • Keynote address: Variations in the natural history of HIV infection
    • Phair JP. Keynote address: variations in the natural history of HIV infection. AIDS Res Hum Retroviruses 1994;10:883-5.
    • (1994) AIDS Res Hum Retroviruses , vol.10 , pp. 883-885
    • Phair, J.P.1
  • 17
    • 0030593031 scopus 로고    scopus 로고
    • Towards an understanding of the correlates of protective immunity to HIV infection
    • Haynes BF, Pantaleo G, Fauci AS. Towards an understanding of the correlates of protective immunity to HIV infection. Science 1996;271:324-8.
    • (1996) Science , vol.271 , pp. 324-328
    • Haynes, B.F.1    Pantaleo, G.2    Fauci, A.S.3
  • 18
    • 0024247580 scopus 로고
    • Patterns of CD4- Cell changes after HIV-1 infection indicate the existence of codeterminant of AIDS
    • Detels R, English AP, Giorgi JV, et al. Patterns of CD4- cell changes after HIV-1 infection indicate the existence of codeterminant of AIDS. J Acquir Immune Defic Syndr 1988;1:390-5.
    • (1988) J Acquir Immune Defic Syndr , vol.1 , pp. 390-395
    • Detels, R.1    English, A.P.2    Giorgi, J.V.3
  • 19
    • 0026061024 scopus 로고
    • Serial CD4 lymphocyte counts and development of AIDS
    • Phillips AN, Lee CA, Elford J, et al. Serial CD4 lymphocyte counts and development of AIDS. Lancet 1991;337:389-92.
    • (1991) Lancet , vol.337 , pp. 389-392
    • Phillips, A.N.1    Lee, C.A.2    Elford, J.3
  • 20
    • 84950459427 scopus 로고
    • Hierarchical Bayes models for the progression of HIV infection using longitudinal CD4 T-cell numbers
    • Lange L, Carlin BP, Gelfand AE. Hierarchical Bayes models for the progression of HIV infection using longitudinal CD4 T-cell numbers. J Am Stat Assoc 1992;87:615-26.
    • (1992) J Am Stat Assoc , vol.87 , pp. 615-626
    • Lange, L.1    Carlin, B.P.2    Gelfand, A.E.3
  • 21
    • 0001083378 scopus 로고
    • Modeling the progression of HIV-1 infection
    • DeGruttola V, Lang N, Dafni U. Modeling the progression of HIV-1 infection. J Am Stat Assoc 1991;86:569-77.
    • (1991) J Am Stat Assoc , vol.86 , pp. 569-577
    • DeGruttola, V.1    Lang, N.2    Dafni, U.3
  • 22
    • 21844510172 scopus 로고
    • A stochastic model for analysis of longitudinal AIDS data
    • Taylor JMG, Cumberland WG, Sy JP. A stochastic model for analysis of longitudinal AIDS data. J Am Stat Assoc 1994;89:727-36.
    • (1994) J Am Stat Assoc , vol.89 , pp. 727-736
    • Taylor, J.M.G.1    Cumberland, W.G.2    Sy, J.P.3
  • 25
    • 0024556660 scopus 로고
    • Patterns of T lymphocyte changes with human immunodeficiency virus infection: From seroconversion to the development of AIDS
    • Lang W, Perkins H, Anderson RE, Royce R, Jewell N, Winkelstein W. Jr. Patterns of T lymphocyte changes with human immunodeficiency virus infection: from seroconversion to the development of AIDS. J Acquir Immune Defic Syndr 1989;2:63-9.
    • (1989) J Acquir Immune Defic Syndr , vol.2 , pp. 63-69
    • Lang, W.1    Perkins, H.2    Anderson, R.E.3    Royce, R.4    Jewell, N.5    Winkelstein Jr., W.6
  • 26
    • 0023229320 scopus 로고
    • Natural history of human immunodeficiency virus infection on hemophiliacs: Effects of T-cell subsets, platelet counts and age
    • Eyster ME, Gail MH, Ballard JO, Al-Mondhiry M, Goedert JJ. Natural history of human immunodeficiency virus infection on hemophiliacs: effects of T-cell subsets, platelet counts and age. Ann Intern Med 1987;107:1-6.
    • (1987) Ann Intern Med , vol.107 , pp. 1-6
    • Eyster, M.E.1    Gail, M.H.2    Ballard, J.O.3    Al-Mondhiry, M.4    Goedert, J.J.5
  • 27
    • 0025759965 scopus 로고
    • CD4% is the best predictor of AIDS in a cohort of HIV-infected homosexual men
    • Burcham J, Marmor M, Dubin N, et al. CD4% is the best predictor of AIDS in a cohort of HIV-infected homosexual men. AIDS 1991; 5:365-72.
    • (1991) AIDS , vol.5 , pp. 365-372
    • Burcham, J.1    Marmor, M.2    Dubin, N.3
  • 28
    • 0027483270 scopus 로고
    • + and declining CD3- Populations suggest regulatory responses linked to loss of CD4 lymphocytes
    • + and declining CD3- populations suggest regulatory responses linked to loss of CD4 lymphocytes. J Acquir Immune Defic Syndr 1993;6:153-61.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 153-161
    • Margolick, J.B.1    Donnenberg, A.D.2    Muñoz, A.3
  • 29
    • 0029009027 scopus 로고
    • Failure of T-cell homeostasis preceding AIDS in HIV-1 infection
    • Margolick JB, Muñoz A, Donnenberg AD, et al. Failure of T-cell homeostasis preceding AIDS in HIV-1 infection. Nature Med 1995;1:674-80.
    • (1995) Nature Med , vol.1 , pp. 674-680
    • Margolick, J.B.1    Muñoz, A.2    Donnenberg, A.D.3
  • 30
    • 0029874749 scopus 로고    scopus 로고
    • Existence and failure of T cell homeostasis prior to AIDS onset in HIV infected injection drug users
    • Galai N, Margolick JB, Astemborski J, Vlahov D. Existence and failure of T cell homeostasis prior to AIDS onset in HIV infected injection drug users. Clin Immunol Immunopathol 1996;79:134-41.
    • (1996) Clin Immunol Immunopathol , vol.79 , pp. 134-141
    • Galai, N.1    Margolick, J.B.2    Astemborski, J.3    Vlahov, D.4
  • 31
    • 0027457969 scopus 로고
    • T-cell homeostasis: Implications in HIV infection
    • Adelman LM, Wofsy D. T-cell homeostasis: implications in HIV infection. J Acquire Immune Defic Syndr 1993;6:144-52.
    • (1993) J Acquire Immune Defic Syndr , vol.6 , pp. 144-152
    • Adelman, L.M.1    Wofsy, D.2
  • 33
    • 13144263832 scopus 로고    scopus 로고
    • Inflection points for CD4, CD8 and CD3 T cell levels and immune activation markers prior to AIDS onset
    • Nishanian P, Taylor JMG, Manna B, et al. Inflection points for CD4, CD8 and CD3 T cell levels and immune activation markers prior to AIDS onset. Immunologist 1997;5(Suppl 1):4.
    • (1997) Immunologist , vol.5 , Issue.1 SUPPL. , pp. 4
    • Nishanian, P.1    Taylor, J.M.G.2    Manna, B.3
  • 34
    • 0023186650 scopus 로고
    • The multicenter AIDS cohort study: Rationale, organization and selected characteristics of the participants
    • Kaslow RA, Ostow DG, Detels R, Phair JP, Polk BF, Rinaldo CR Jr. The multicenter AIDS cohort study: rationale, organization and selected characteristics of the participants. Am J Epidemiol 1987; 126:310-18.
    • (1987) Am J Epidemiol , vol.126 , pp. 310-318
    • Kaslow, R.A.1    Ostow, D.G.2    Detels, R.3    Phair, J.P.4    Polk, B.F.5    Rinaldo Jr., C.R.6
  • 35
    • 0023089664 scopus 로고
    • Significance of quantitative enzyme-linked immunosorbent assay (ELISA) results in evaluation of three ELISAs and Western blot tests for detection of antibodies to human immunodeficiency virus in a high-risk population
    • Nishanian P, Taylor JM, Korns E, Detels R, Saah A, Fahey JL. Significance of quantitative enzyme-linked immunosorbent assay (ELISA) results in evaluation of three ELISAs and Western blot tests for detection of antibodies to human immunodeficiency virus in a high-risk population. J Clin Microbiol 1987;25:395-400.
    • (1987) J Clin Microbiol , vol.25 , pp. 395-400
    • Nishanian, P.1    Taylor, J.M.2    Korns, E.3    Detels, R.4    Saah, A.5    Fahey, J.L.6
  • 36
    • 0027512897 scopus 로고
    • Evaluation of a dual-color flow cytometry immunophenotyping panel in a multicenter quality assurance program
    • Schenker EL, Hultin LE, Bauer KD, et al. Evaluation of a dual-color flow cytometry immunophenotyping panel in a multicenter quality assurance program. Cytometry 1993;14:307-17.
    • (1993) Cytometry , vol.14 , pp. 307-317
    • Schenker, E.L.1    Hultin, L.E.2    Bauer, K.D.3
  • 38
    • 16944366524 scopus 로고    scopus 로고
    • Late escape from an immunodominant cytotoxic T lymphocyte response associated with progression to AIDS
    • Goulder PJR, Phillips RE, Colbert RA, et al. Late escape from an immunodominant cytotoxic T lymphocyte response associated with progression to AIDS. Nature Med 1997;3:212-17.
    • (1997) Nature Med , vol.3 , pp. 212-217
    • Goulder, P.J.R.1    Phillips, R.E.2    Colbert, R.A.3
  • 42
    • 0021264311 scopus 로고
    • Immune response-associated production of neopterin: Release from macrophages primarily under control of interferon-gamma
    • Huber C, Batchelor JR, Fuchs D, et al. Immune response-associated production of neopterin: release from macrophages primarily under control of interferon-gamma. J Exp Med 1984;160: 310-16.
    • (1984) J Exp Med , vol.160 , pp. 310-316
    • Huber, C.1    Batchelor, J.R.2    Fuchs, D.3
  • 43
    • 0026625694 scopus 로고
    • Different lymphoid cell populations produce varied levels of neopterin, β2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, interferon-gamma or tumor necrosis factor-alpha
    • Hofmann B, Bass H, Nishanian P, et al. Different lymphoid cell populations produce varied levels of neopterin, β2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, interferon-gamma or tumor necrosis factor-alpha. Clin Exp Immunol 1992; 88:548-54.
    • (1992) Clin Exp Immunol , vol.88 , pp. 548-554
    • Hofmann, B.1    Bass, H.2    Nishanian, P.3
  • 44
    • 0028140219 scopus 로고
    • Serum levels of tumor necrosis factor-α (TNFα) and soluble TNF receptors in human immunodeficiency virus type 1 infection - Correlations to clinical, immunologic and virologic parameters
    • Aukrust P, Liabakk N-B, Müller F, Lien E, Espevik T, Frøland SS. Serum levels of tumor necrosis factor-α (TNFα) and soluble TNF receptors in human immunodeficiency virus type 1 infection - correlations to clinical, immunologic and virologic parameters. J Infect Dis 1994;169:420-4.
    • (1994) J Infect Dis , vol.169 , pp. 420-424
    • Aukrust, P.1    Liabakk, N.-B.2    Müller, F.3    Lien, E.4    Espevik, T.5    Frøland, S.S.6
  • 46
    • 0026333671 scopus 로고
    • Cytokines and HIV infection: Is AIDS a tumor necrosis factor disease?
    • Matsuyama T, Kobayashi N, Yamamoto N. Cytokines and HIV infection: is AIDS a tumor necrosis factor disease? AIDS 1991;5: 1405-17.
    • (1991) AIDS , vol.5 , pp. 1405-1417
    • Matsuyama, T.1    Kobayashi, N.2    Yamamoto, N.3
  • 47
    • 0028181516 scopus 로고
    • Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation
    • Zangerle R, Gallati H, Sarcletti M, et al. Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation. J Acquir Immune Defic Syndr 1994;7:79-85.
    • (1994) J Acquir Immune Defic Syndr , vol.7 , pp. 79-85
    • Zangerle, R.1    Gallati, H.2    Sarcletti, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.