Characterization of human anti-high molecular weight-melanoma-associated antigen single-chain Fv fragments isolated from a phage display antibody library

Cancer Research

Volumn 58, Issue 11, 1998, Pages 2417-2425

  Desai, Smruti A ^a   Wang, Xinhui ^a   Noronha, Elvyra J ^a   Kageshita, Toshiro ^a   Ferrone, Soldano ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; MELANOMA ANTIGEN; MONOCLONAL ANTIBODY; NUCLEOTIDE;

ANIMAL CELL; ARTICLE; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPRECIPITATION; IMMUNOTHERAPY; MELANOMA; MOUSE; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGE DISPLAY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SEROLOGY;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; BACTERIOPHAGE M13; GENE LIBRARY; GUINEA PIGS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; MELANOMA; MICE; NEOPLASM PROTEINS; PEPTIDE LIBRARY; RATS; TUMOR CELLS, CULTURED;

EID: 0032101056     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Reisfeld, R. A., and Cheresh, D. A. Human tumor antigens. Adv. Immunol., 40: 323-377, 1987.
2. Kerrone, S., Temponi, M., Gargiulo, D., Scassellati, G. A., Cavaliere, R., and Natali, P. G. Selection and utilization of monoclonal antibody defined melanoma associated antigens for immunoscintigraphy in patients with melanoma. In: S. C. Srivastava (ed.), Radiolabeled Monoclonal Antibodies for Imaging and Therapy, pp. 55-73. New York and London: Plenum Press, 1988.
3. 2 fragments. Cancer Res., 45: 3378-3387, 1985.
4. Siccardi, A. G., Buraggi, G. L., Natali, P. G., Scassellati, G. A., Viale, G., and Ferrone, S. European multicentre study on melanoma immunoscintigraphy by means of 99mTc-labelled monoclonal antibody fragments. The European Multicentre Study Group. Eur. J. Nucl. Med., 16: 317-323, 1990.
5. Spitler, L. E., del Rio, M., Khenigan, A., Wedel, N. I., Brophy, N. A., Miller, L. L., Harkonen, W. S., Rosendorf, L. L., Lee, H. M., Mischak, R. P., Kawahata, R. T., Stoudemire, J. B., Fradkin, L. B., Bautista, E. E., and Scannon, P. J. Therapy of patients with malignant melanoma using a monoclonal antimelanoma antibody-ricin A chain immunotoxin. Cancer Res., 47: 1717-1723, 1987.
6. Mittelman, A., Chen, Z. J., Kageshita, T., Yang, H., Yamada, M., Baskind, P., Goldberg, N., Puccio, C., Ahmed, T., Arlin, Z., and Ferrone, S. Active specific immunotherapy in patients with melanoma: a clinical trial with mouse anti-idiotypic monoclonal antibodies elicited with syngeneic anti-high-molecular-weight-melanoma-associated antigen monoclonal antibodies. J. Clin. Invest., 86: 2136-2144, 1990.
7. Quan, W. D. Y., Jr., Dean, G. E., Spears, L., Spears, C. P., Groshen, S., and Merritt, M. S. Active specific immunotherapy of metastatic melanoma with an antiidiotype vaccine: a Phase I/II trial of I-mel-2 plus SAF-m. J. Clin. Oncol., 15: 2103-2110, 1997.
8. Winter, G., Griffiths, A. D., Hawkins, R. E., and Hoogenboom, H. R. Making antibodies by phage display technology. Annu. Rev. Immunol., 12: 433-455, 1994.
9. Burton, D. R., and Barbas, C. F., III. Human antibodies from combinatorial libraries. Adv. Immunol., 57: 191-280, 1994.
10. Giacomini, P., Ng, A. K., Kantor, R. R. S., Natali, P. G., and Ferrone, S. Double determinant immunoassay to measure a human high-molecular-weight melanoma-associated antigen. Cancer Res., 43: 3586-3590, 1983.
11. Wilson, B. S., Imai, K., Natali, P. G., and Ferrone, S. Distribution and molecular characterization of a cell-surface and a cytoplasmic antigen detectable in human melanoma cells with monoclonal antibodies. Int. J. Cancer, 28: 293-300, 1981.
12. Temponi, M., Gold, A. M., and Ferrone, S. Binding parameters and idiotypic profile of the whole immunoglobulin and Fab′ fragments of murine monoclonal antibody to distinct determinants of the high molecular weight-melanoma-associated antigen. Cancer Res., 52: 2497-2503, 1992.
13. Chen, Z. J., Yang, H., Kageshita, T., and Ferrone, S. Human high molecular weight melanoma-associated antigen mimicry by mouse antiidiotypic monoclonal antibody TK7-371. Cancer Res., 51: 4790-4797, 1991.
14. Imai, K., Wilson, B. S., Natali, P. G., and Ferrone, S. A 94,000-dalton glycoprotein expressed by human melanoma and carcinoma cells. J. Natl. Cancer Inst., 68: 761-769, 1982.
15. Imai, K., Natali, P. G., Kay, N. E., Wilson, B. S., and Ferrone, S. Tissue distribution and molecular profile of a differentiation antigen detected by a monoclonal antibody (345.134S) produced against human melanoma cells. Cancer Immunol. Immunother., 12: 159-166, 1982.
16. Kusama, M., Kageshita, T., Chen, Z. J., and Ferrone, S. Characterization of syngeneic antiidiotypic monoclonal antibodies to murine anti-human high molecular weight melanoma-associated antigen monoclonal antibodies. J. Immunol., 143: 3844-3852, 1989.
17. 2m gene expression. J. Clin. Invest., 87: 284-292, 1991.
18. Nishiyama, A., and Stallcup, W. B. Expression of NG2 proteoglycan causes retention of type VI collagen on the cell surface. Mol. Biol. Cell, 4: 1097-1108, 1993.
19. Evan, G. I., Lewis, G. K., Ramsay, G., and Bishop, J. M. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol., 5: 3610-3616, 1985.
20. Wang, X., Desai, S., Noronha, E. J., Mittelman, A., and Ferrone, S. The anti-idiotypic approach to active specific immunotherapy of malignant melanoma. In: Y. Shoenfeld, R. C. Kennedy, and S. Ferrone (eds.), Idiotypes in Medicine: Autoimmunity, Infection, and Cancer, pp. 523-536. Amsterdam: Elsevier Publications, 1997.
21. Temponi, M., Kageshita, T., Perosa, F., Ono, R., Okada, H., and Ferrone, S. Purification of murine IgG monoclonal antibodies by precipitation with caprylic acid: comparison with other methods of purification. Hybridoma, 8: 85-95, 1989.
22. Nissim, A., Hoogenboom, H. R., Tomlinson, I. M., Flynn, G., Midgley, C., Lane, D., and Winter, G. Antibody fragments from a "single pot" phage display library as immunochemical reagents. EMBO J., 13: 692-298, 1994.
23. H segments with different hypervariable loops. J. Mol. Biol., 227: 776-798, 1992.
24. H gene segments rearranged in vitro. J. Mol. Biol., 227: 381-388, 1992.
25. Marks, J. D., Hoogenboom, H. R., Bonnert, T. P., McCafferty, J., Griffiths, A. D., and Winter, G. By-passing immunisation. Human antibodies from V-gene libraries displayed on phage. J. Mol. Biol., 222: 581-597, 1991.
26. Harrison, J. L., Williams, S. C., Winter, G., and Nissim, A. Screening of phage antibody libraries. Methods Enzymol., 267: 83-109, 1996.
27. Miller, J. H. Experiments in Molecular Genetics. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1972.
28. Schier, R., McCall, A., Adams, G. P., Marshall, K. W., Merritt, H., Yim, M., Crawford, R. S., Weiner, L. M., Marks, C., and Marks, J. D. Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site. J. Mol. Biol., 263: 551-567, 1996.
29. Skerra, A., and Pluckthun, A. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science (Washington DC), 240: 1038-1041, 1988.
30. Sanger, F., Nicklen, S., and Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA, 74: 5463-5467, 1977.
31. Tomlinson, I. M., Williams, S. C., Corbett, S. J., Cox, J. P. L., and Winter, G. Vbase Sequence Directory. Cambridge, United Kingdom: MRC Centre for Protein Engineering, 1995.
32. Zweig, S. E., and Shevach, E. H. Production and properties of monoclonal antibodies to guinea pig Ia antigens. Methods Enzymol., 92: 66-85, 1983.
33. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (Lond.), 227: 680-685, 1970.
34. Kageshita, T., Hirai, S., Ono, T., and Ferrone, S. Human high molecular weight-melanoma associated antigen mimicry by mouse anti-idiotypic MAb MK2-23: immunohistochemical analysis of the reactivity of anti-anti-idiolypic MAb with surgically removed melanoma lesions. Int. J. Cancer, 60: 334-340, 1995.
35. Liao, S-K., Smith, J. W., Kwong, P. C., Natali, P. G., Kusama, M., Hamby, C. V., and Ferrone, S. Cross-reactivity of murine anti-human high molecular weight-melanoma-associated antigen monoclonal antibodies with guinea pig melanoma cells. Cancer Res., 47: 4835-4841, 1987.
36. Tajiri, K., Uchida, N., and Tanzer, M. L. Undersulfated proteoglycans secreted by cultured chondrocytes in the presence of the ionophore monensin. J. Biol. Chem., 255: 6036-6039, 1980.
37. Bumol, T. F., and Reisfeld, R. A. Unique glycoprotein-proteoglycan complex defined by monoclonal antibody on human melanoma cells. Proc. Natl. Acad. Sci. USA, 79: 1245-1249, 1982.
38. Ross, A. H., Cossu, G., Herlyn, M., Bell, J. R., Steplewski, Z., and Koprowski, H. Isolation and chemical characterization of a melanoma-associated proteoglycan antigen. Arch. Biochem. Biophys., 225: 370-383, 1983.
39. Hellstrom, I., Garrigues, H. J., Cabasco, L., Mosely., G. H., Brown, J. P., and Hellstrom, K. E. Studies of a high molecular weight human melanoma-associated antigen. J. Immunol., 130: 1467-1472, 1983.
40. Kantor, R. R. S., Albino, A. P., Ng, A. K., and Ferrone, S. Biosynthesis and intracellular processing of four human melanoma-associated antigens. Cancer Res., 46: 5223-5228, 1986.
41. Nakamuro, K., Tanigaki, N., and Pressman, D. Isolation of HL-A 33,000-dalton fragments carrying high HL-A alloantigenic activity. Transplantation (Baltimore), 19: 431-437, 1975.
42. Hodits, R. A., Nimpf, J., Pfistermueller, D. M., Hiesberger, T., Schneider, W. J., Vaughan, T. J., Johnson, K. S., Haumer, M., Kuechler, E., Winter, G., and Blaas, D. An antibody fragment from a phage display library competes for ligand binding to the low density lipoprotein receptor family and inhibits rhinovirus infection. J. Biol. Chem., 270: 24078-24085, 1995.
43. Pilkington, G. R., Duan, L., Zhu, M., Keil, W., and Pomerantz, R. J. Recombinant human Fab antibody fragments to HIV-1 Rev and Tat regulatory proteins: direct selection from a combinatorial phage display library. Mol. Immunol., 33: 439-450, 1996.
44. Nishiyama, A., Dahlin, K. J., Prince, J. T., Johnstone, S. R., and Stallcup, W. B. The primary structure of NG2, a novel membrane-spanning proteoglycan. J. Cell Biol., 114: 359-371, 1991.
45. Pluschke, G., Vanek, M., Evans, A., Dittmar, T., Schmid, P., Itin, P., Filardo, E. J., and Reisfeld, R. A. Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan. Proc. Natl. Acad. Sci. USA, 93: 9710-9715, 1996.
46. Cai, X., and Garen, A. Anti-melanoma antibodies from melanoma patients immunized with genetically modified autologous tumor cells: selection of specific antibodies from single-chain Fv fusion phage libraries. Proc. Natl. Acad. Sci. USA, 92: 6537-6541, 1995.
47. H antibody cloned from a fusion phage library of a vaccinated melanoma patient. Proc. Natl. Acad. Sci. USA, 93: 6280-6285, 1996.
48. Pereira, S., Van Belle, P., Elder, D., Maruyama, H., Jacob, L., Sivanandham, M., Wallack, M., Siegel, D., and Herlyn, D. Combinatorial antibodies against human malignant melanoma. Hybridoma, 16: 11-15, 1997.
49. Sanna, P. P., Williamson, R. A., De Logu, A., Bloom, F. E., and Burton, D. R. Directed selection of recombinant human monoclonal antibodies to herpes simplex virus glycoproteins from phage display libraries. Proc. Natl. Acad. Sci. USA, 92: 6439-6443, 1995.