Synchronous oral carcinomas: Independent or common clonal origin?

Cancer Research

Volumn 58, Issue 9, 1998, Pages 2003-2006

  Scholes, Andrea G M ^a   Woolgar, Julia A ^a   Boyle, Mark A ^a,b   Brown, James S ^b   Vaughan, E David ^b   Hart, C Anthony ^a   Jones, Andrew S ^a   Field, John K ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b WALTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

ALLELE; ARTICLE; CANCER SURVIVAL; CHROMOSOME 17P; CHROMOSOME 3P; CHROMOSOME 9P; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CLONOGENESIS; EPITHELIUM DYSPLASIA; HUMAN; HUMAN TISSUE; MALE; MOUTH CANCER; MULTIPLE CANCER; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ALLELES; CARCINOMA, SQUAMOUS CELL; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 9; DNA, NEOPLASM; GENE DELETION; HUMANS; LEUKOPLAKIA, ORAL; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MOUTH NEOPLASMS; POLYMERASE CHAIN REACTION;

EID: 0032080610     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Carr, R. J., and Langdon, J. D. Multiple primaries in mouth cancer: the price of success. Br. J. Oral Maxillofac. Surg., 27: 394-399, 1989.
2. Lippman, S. M., and Hong, W. K. Second malignant tumors in head and neck squamous cell carcinoma: the overshadowing threat for patients with early-stage disease. Int. J. Radiat. Oncol. Biol. Phys., 17: 691-694, 1989.
3. Cooper, J. S., Pajak, T. F., Rubin, P., Tupchong, L., Brady, L. W., Leibel, S. A., Laramore, G. E., Marcial, V. A., Davis, L. W., and Cox, J. D. Second malignancies in patients who have head and neck cancer: incidence, effect on survival and implications based on the RTOG experience. Int. J. Radiat. Oncol. Biol. Phys., 17: 449-456, 1989.
4. de Vries, N. The magnitude of the problem. In: N. de Vries and J. L. Gluckman (eds.), Multiple Primary Tumors in the Head and Neck, pp. 1-29. Stuttgart, Germany: Georg Thieme Verlag, 1990.
5. Slaughter, D. P., Southwick, H. W., and Smejkal, W. "Field cancerization" in oral stratified squamous epithelium. Clinical implications of multicentric origin. Cancer (Phila.), 6: 963-968, 1953.
6. Chung, K. Y., Mukhopadhyay, T., Kim, J., Casson, A., Ro, J. Y., Goepfert, H., Hong, W. K., and Roth, J. A. Discordant p53 mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res., 53: 1676-1683, 1993.
7. Worsham, M. J., Wolman, S. R., Carey, T. E., Zarbo, R. J., Benninger, M. S., and Van Dyke, D. L. Common clonal origin of synchronous primary head and neck squamous cell carcinomas: analysis by tumor karyotypes and fluorescence in situ hybridization. Hum. Pathol., 26: 251-261, 1995.
8. Bedi, G. C., Westra, W. H., Gabrielson, E., Koch, W., and Sidransky, D. Multiple head and neck tumors: evidence for a common clonal origin. Cancer Res., 56: 2484-2487, 1996.
9. Ah-See, K. W., Cooke, T. G., Pickford, I. R., Soutar, D., and Balmain, A. An allelotype of squamous carcinoma of the head and neck using microsatellite markers. Cancer Res., 54: 1617-1621, 1994.
10. Nawroz, H., van der Riet, P., Hruban, R. H., Koch, W., Ruppert, J. M., and Sidransky, D. Allelotype of head and neck squamous cell carcinoma. Cancer Res., 54: 1152-1155, 1994.
11. Wu, C. L., Sloan, P., Read, A. P., Harris, R., and Thakker, N. Deletion mapping on the short arm of chromosome 3 in squamous cell carcinoma of the oral cavity. Cancer Res., 54: 6484-6488, 1994.
12. Field, J. K., Kiaris, H., Risk, J. M., Tsiriyotis, C., Adamson, R., Zoumpourlis, V., Rowley, H., Taylor, K., Whittaker, J., Howard, P., Beirnie, J. C., Gosney, J. R., Woolgar, J., Vaughan, E. D., Spandidos, D. A., and Jones, A. S. Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival. Br. J. Cancer, 72: 1180-1188, 1995.
13. Field, J. K., Kiaris, H., Howard, P., Vaughan, E. D., Spandidos, D. A., and Jones, A. S. Microsatellite instability in squamous cell carcinoma of the head and neck. Br. J. Cancer. 71: 1065-1069, 1995.
14. Liloglou, T., Scholes, A. G. M., Spandidos, D. A., Vaughan, E. D., Jones, A. S., and Field, J. K. p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability. Cancer Res., 57: 4070-4074, 1997.
15. Sozzi, G., Miozzo, M., Pastorino, U., Pilotti, S., Donghi, R., Giarola, M., De Gregorio, L., Manenti, G., Radice, P., Minoletti, F., Della Porta, G., and Pierotti, M. A. Genetic evidence for an independent origin of multiple preneoplastic and neoplastic lung lesions. Cancer Res., 55: 135-140, 1995.
16. Waridel, F., Estreicher, A., Bron, L., Flaman, J-M., Fontolliet, C., Monnier, P., Frebourg, T., and Iggo, R. Field cancerization and polyclonal p53 mutation in the upper aerodigestive tract. Oncogene, 14: 163-169, 1997.
17. Boyle, J. O., Hakim, J., Koch, W., van der Riet, P., Hruban, R. H., Roa, R. A., Correo, R., Eby, Y. J., Ruppert, J. M., and Sidransky, D. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res., 53: 4477-4480, 1993.
18. Nees, M., Homann, N., Discher, H., Andl, T., Enders, C., Herold-Mende, C., Schuhmann, A., and Bosch, F. X. Expression of mutated p53 occurs in tumor-distant epithelia of head and neck cancer patients: a possible molecular basis for the development of multiple tumors. Cancer Res., 53: 4189-4196, 1993.