Regulation of the erythroid transcription factor NF-E2 by cyclic adenosine monophosphate-dependent protein kinase

Blood

Volumn 91, Issue 9, 1998, Pages 3193-3201

  Casteel, Darren ^a   Suhasini, Modem ^a   Gudi, Tanima ^a   Naima, Reza ^a   Pilz, Renate B ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; NUCLEAR FACTOR; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBUNIT; ERYTHROLEUKEMIA; HEMOGLOBIN SYNTHESIS; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; TRANSCRIPTION REGULATION;

EID: 0032079790     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v91.9.3193.3193_3193_3201     Document Type: Article

References (50)

1. Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH: Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature 362:722, 1993
2. Ney PA, Andrews NC, Jane SM, Safer B, Purucker ME, Weremowicz S, Morton CC, Goff SC, Orkin SH, Nienhuis AW: Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol 13:5604, 1993
3. Blank V, Kim MJ, Andrews NC: Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression. Blood 89:3925-3935, 1997
4. Igarashi K, Itoh K, Motohashi H, Hayashi N, Matuzaki Y, Nakauchi H, Nishizawa M, Yamamoto M: Activity and expression of murine small Maf family protein MafK. J Biol Chem 270:7615, 1995
5. Talbot D, Grosveld F: The 5'HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites. EMBO J 10:1391, 1991
6. Gong Q, McDowell JC, Dean A: Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5' hypersensitive site 2 of the β-globin locus control region. Mol Cell Biol 16:6055, 1996
7. Armstrong JA, Emerson BM: NF-E2 Disrupts chromatin structure at human β-globin locus control region hypersensitive site 2 in vitro. Mol Cell Biol 16:5634, 1996
8. II130 and mediates long-range activation of the α- and β-globin gene locus in an erythroid cell line. Proc Natl Acad Sci USA 94:10051, 1997
9. Lu S-J, Rowan S, Bani MR, Ben-David Y: Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: Evidence that NF-E2 is essential for globin expression. Proc Natl Acad Sci USA 91:8398, 1994
10. Kotkow KJ, Orkin SH: Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer. Mol Cell Biol 15:4640, 1995
11. Shidasani RA, Rosenblatt MF, Zucker-Franklin D, Jackson CW, Hunt P, Saris CJM, Orkin SH: Transcription factor NF-E2 is required for platelet formation independent of the actions of thrombopoietin/ MGDF in megakaryocyte development. Cell 81:695, 1995
12. Shivdasani R, Orkin SH: Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2. Proc Natl Acad Sci USA 92:8690, 1995
13. Moi P, Chan K, Asunis I, Cao A, Kan YW: Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the β-globin locus control region. Proc Natl Acad Sci USA 91:9926, 1994
14. Caterina JJ, Donze D, Sun C-W, Ciavatta DJ, Townes TM: Cloning and functional characterization of LCR-F1: A bZIP transcription factor that activates erythroid-speciric, human globin gene expression. Nucl Acids Res 22:2383, 1994
15. Chan JY, Han X-L, Kan YW: Cloning of Nrfl, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci USA 90:11371, 1993
16. Chui DHK, Tang W, Orkin SH: cDNA cloning of murine Nrf2 gene, coding for a p45 NF-E2 related transcription factor. Biochem Biophys Res Commun 209:40, 1995
17. Fraser PJ, Curtis PJ: Specific pattern of gene expression during induction of mouse erythroleukemia cells. Genes Dev 1:855, 1987
18. Garingo AD, Suhasini M, Andrews NC, Pilz RB: cAMP-dependent protein kinase is necessary for increased NF-E2/DNA complex formation during erythroleukemia cell differentiation. J Biol Chem 270:9169, 1995
19. Pilz RB: Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. J Biol Chem 268:20252, 1993
20. Cheng X, Reginato MJ, Andrews NC, Lazar MA: The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2. Mol Cell Biol 17:1407, 1997
21. maj-globin promoter. J Biol Chem 270:6619, 1995
22. Fukumoto H, Matsui Y, Obinata M: Mechanism of erythropoietin action on the erythroid progenitor cells induced from murine erythroleukemia cells (TSA8). Development 105:109, 1989
23. Kuramochi S, Sugimoto Y, Ikawa Y, Todokoro K: Transmembrane signaling during erythropoietin- and dimethylsulfoxide-induced erythroid cell differentiation. Eur J Biochem 193:163, 1990
24. Deng WP, Nickloff JA: Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal Biochem 200:81, 1992
25. Sambrook J: Molecular Cloning: A Laboratory Manual. New York. NY, Cold Spring Harbor Laboratory, 1989
26. Helmberg A, Auphan N, Caelles C, Karin M: Glucocorticoid-induced apoptosis of human leukemic cells is caused by the repressive function of the glucocorticoid receptor. EMBO J 14:452, 1995
27. Sadowski I, Ptashne M: A vector for expression GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res 17:7539, 1989
28. Armstrong R, Wen W, Meinkoth J, Taylor S, Montminy M: A refractory phase in cyclic AMP-responsive transcription requires down regulation of protein kinase A. Mol Cell Biol 15:1826, 1995
29. Deng T, Karin M: JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers. Genes Dev 7:479, 1993
30. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin S-C, Heyman RA, Rose DW, Glass Ck, Rosenfeld MG: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403, 1996
31. Pilz RB, Eigenthaler M, Boss GR: Chemically-induced murine erythroleukemia cell differentiation is severely impaired when cAMP-dependent protein kinase activity is repressed by transfected genes. J Biol Chem 267:16161, 1992
32. Gudi T, Huvar I, Meinecke M, Lohmann SM, Boss GR, Pilz RB: Regulation of gene expression by cGMP-dependent protein kinase. J Biol Chem 271:4597, 1996
33. Boyle WJ, Van der Geer P, Hunter T: Phosphopeptide mapping and phosphorylation site determination, in Hunter T, Sefton BM (eds): Methods in Enzymol. San Diego, CA, Academic, 1991, p 110
34. Halbrugge M, Friedrich C, Eigenthaler M, Schanzenbacher P, Walter U: Stoichiometric and reversible phosphorylation of a 46-kDa protein in human platelets in response to cGMP- and cAMP-elevating vasodilators. J Biol Chem 265:3088, 1990
35. ras-mitogen-activated protein kinase pathway in fibroblasts. J Biol Chem 269:3534, 1994
36. Angel P, Karin M: The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072:129, 1991
37. Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M: Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367:568, 1994
38. Bean TL, Ney PA: Multiple regions of p45 NF-E2 are required for β-globin gene expression in erythroid cells. Nucl Acids Res 25:2509, 1997
39. Labbaye C, Valtieri M, Barberi T, Meccia E, Pelosi E, Condorelli GL, Testa U, Peschle C: Differential expression and functional role of GATA-2 NE-E2, and GATA-1 in normal adult hematopoiesis. J Clin Invest 95:2346, 1995
40. Strauss EC, Andrews NC, Higgs DR, Orkin SH: In vivo footprinting of the human α-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. Mol Cell Biol 12:2135, 1992
41. Strauss EC, Orkin SH: In vivo protein-DNA interactions at hypersensitive site 3 of the human β-globin locus control region. Proc Natl Acad Sci USA 89:5809, 1992
42. Oyake T, Iton K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M, Yamamoto M, Igarashi K: Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16:6083, 1996
43. Crossley M, Orkin SH: Phosphorylation of the erythroid transcription factor GATA-1. J Biol Chem 269:16589, 1994
44. Schüle R, Rangarajan P, Kliewer S, Ransome LJ, Bolado J, Yang N, Verma IM, Evans RM: Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 62:1217, 1990
45. Schule R, Rangarajan P, Yang N, Kliewer S, Ransone LJ, Bolado J, Verma IM, Evans RM: Retinoic acid is a negative regulator of AP-1-responsive genes. Proc Natl Acad Sci USA 88:6092, 1991
46. Chrivia JC, Kwok RPS, Lamb N, Hagiwara M, Montminy MR, Goodman RH: Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855, 1993
47. Brindle P, Nakajima T, Montminy M: Multiple protein kinase A-regulated events are required for transcriptional induction by cAMP. Proc Natl Acad Sci USA 92:10521, 1995
48. Gavva NR, Gavva R, Ermekova K, Sudol M, Shen CKJ: Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II. J Biol Chem 272:24105, 1997
49. Suhasini M, Reddy CD, Reddy EP, Didonato JA, Pilz, RP: cAMP-induced NF-KB (p50/relB) binding to a c-myb intronic enhancer correlates with c-myb up-regulation and inhibition of erythroleukemia cell differentiation. Oncogene 15:1859, 1997
50. Chan JY, Han X-L, Kan YW: Isolation of a cDNA encoding the human NF-E2 protein. Proc Natl Acad Sci USA 90:11366, 1993