Hypoxanthine, guanine, xanthine phosphoribosyltransferase activity in Cryptosporidium parvum

Experimental Parasitology

Volumn 89, Issue 1, 1998, Pages 9-15

  Doyle, Patricia S ^a   Kanaani, Jamil ^a   Wang, Ching C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; CELL CULTURE; CELL STRAIN; CRYPTOSPORIDIUM PARVUM; ENZYME ACTIVITY; IN VITRO STUDY; PRIORITY JOURNAL; SPOROZOITE;

CRYPTOSPORIDIUM; CRYPTOSPORIDIUM PARVUM; EIMERIA; PROTOZOA; TOXOPLASMA;

EID: 0032079094     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1998.4263     Document Type: Article

References (22)

1. Wang, C. C., and Simashkevich, P. M. 1981. Purine metabolism in the protozoan parasite Eimeria tenella. Procedings of the National Academy of Science, USA 78, 6618-6622.
2. Krug, E. C., Marr, J. J., and Berens, R. L. 1989. Purine metabolism in Toxoplasma gondii. Journal of Biological Chemistry, 264, 10601-10607.
3. Wang, C. C., Simashkevich, P. M., and Stotish, R. L. 1979. Mode of anticoccidial action of arprinocid. Biochemical Pharmacology 28, 2241-2248
4. Doyle, P. S., Crabb, J., and Petersen, C. 1993. Anti-Cryptosporidium parvum antibodies inhibit infection in vitro and in vivo. Infection and Immunity, 61, 4079-4081.
5. Pfefferkorn, E. R., and Pfefferkorn, L. C. 1977. T. gondii: Specific labeling of nucleic acids of intracellular parasites in Lesch-Nyhan cells. Experimental Parasitology, 41, 95-104.
6. Gero, A. M., and O'Sullivan, W. J. 1990. Purines and pyrimidines in malarial parasites. Blood Cells, 16, 467-484.
7. Roth, E. F., Ruprecht, R. M., Schulman, S., Vanderberg, J., and Olsen, J. A. 1986. Ribose metabolism and nucleic acid synthesis in normal and glucose-6-phosphate dehydrogenase-deficient human erythrocytes infected with Plasmodium falciparum. Journal of Clinical Investigation, 77, 1129-1135.
8. Schwab, J. C, Afifi Afifi, M., Pizzorno, G., Handschumacher, R. E, Joiner, K. A. 1995. Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter. Molecular and Biochemical Parasitology, 70, 59-69.
9. Beck, J., and Wang, C. C. 1993. The hypoxanthine-guanine-xanthine phosphoribosyltrasferase from T. foetus has unique properties. Molecular and Biochemical Parasitology, 60, 187-194.
10. Maga, G., Spadari, S., Wright, G. E., and Focher, F. 1994. Identification, partial purification, and inhibition by guanine analogues of a novel enzymic activity which phosphorylates guanosine to GMP in the protozoan parasite Eimeria tenella. Biochemical Journal, 298, 289-294.
11. Wang, C. C. 1995. Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis. Annual Review of Pharmacology and Toxicology, 35, 93-127.
12. Allen, T. E., and Ullman, B. 1994. Molecular characterization and overexpression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma cruzi. Molecular and Biochemical Parasitology, 65, 233-245.
13. Allen, T. E., and Ullman, B. 1993. Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase gene from Trypanosoma brucei. Nucleic Acids Research, 21 (23), 5431-5438.
14. Allen, T. E., Hwang, H. Y., Jardim, A., Olafson, R., and Ullman, B. 1995. Cloning and expression of the hypoxanthine-guanine phosphoribosyltransferase from Leishmania donovani. Molecular and Biochemical Parasitology, 73, 133-143.
15. Queen, S., Vander Jagt, D., and Reyes, P. 1988. Properties and substrate specificity of a purine phosphoribosyltransferase from the human parasite Plasmodium falciparum. Molecular and Biochemical Parasitology, 30, 123-134.
16. Naguib, F. N. M., Iltzsch, M. H., ElKouni, M. M., Panzica, R. P., and ElKouni, M. H. 1995. Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosylatransferase from Toxoplasma gondii. Biochemical Pharmacology 50, 1685-1693.
17. Kooij, A., Bosch, K. S., Frederiks, V. M., and Van Noorden, C. J. 1992. High levels of xanthine oxidoreductase in rat endothelial, epithelial, and connective tissue cells. A relation between localization and function. Virchows Archives of Cell Pathology, 62, 143-150.
18. Sommer, J. M., Ma, H., and Wang, C. C. 1995. Cloning, expression, and characterization of an unusual guanine phosphoribosyltransferase from Giardia lamblia. Molecular and Biochemical Parasitology, 78, 185-193.
19. Somoza, J. R., Chin, M. S., Focia, P. J., Wang C. C., and Fletterick, R. J. 1996. Crystal structure of the hypoxanthine-guanine-xanthine phosphoribosyltransferase from the protozoan parasite Tritrichomonas foetus. Biochemistry, 35, 7032-7040.
20. Frederiks, W. M., Marx, F., and Kooij, A. 1993. The effect of ischemia on xanthine oxidase activity in rat intestine and liver. International Journal of Experimental Pathology, 74, 21-26.
21. Pfeffer, K. D., Hueckstead, T. P., and Hoidal. J. R., 1994. Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation. Journal of Immunology, 153, 1789-1797.
22. Wang, C. C., Verham, R., Rice, A., and Tzeng, S. 1983. Purine salvage by Trichomonas foetus. Molecular and Biochemical Parasitology, 8, 325-337.