Ionotropic glutamate receptors in the retina: Moving from molecules to circuits

Vision Research

Volumn 38, Issue 10, 1998, Pages 1399-1410

  Lo, Wayne ^a   Molloy, Raymond ^a   E Hughes, Thomas ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Circuits; Green fluorescent protein; Ionotropic glutamate receptors; Molecules; Retina

Indexed keywords

GLUTAMATE RECEPTOR; GREEN FLUORESCENT PROTEIN; ION CHANNEL; IONOTROPIC RECEPTOR; RECEPTOR SUBUNIT;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL TISSUE; CHANNEL GATING; CONFERENCE PAPER; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNOHISTOCHEMISTRY; JELLYFISH; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DENSITY; RETINA; RETINA NERVE CELL; SYNAPSE;

EID: 0032078236     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6989(98)00008-X     Document Type: Conference Paper

References (65)

1. Nakanishi S. Molecular diversity of glutamate receptors and implications for brain function. Science. 258:1992;597-603.
2. Hollmann M., Heinemann S. Cloned glutamate receptors. Ann Rev Neurosci. 17:1994;31-108.
3. Sugihara H., Moriyoshi K., Ishii T., Masu M., Nakanishi S. Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem Biophys Res Commun. 185:1992;826-832.
4. Hollmann M., Boulter J., Maron C., Beasley L., Sullivan J., Pecht G., Heinemann S. Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor. Neuron. 10:1993;943-954.
5. 2+ permeability of KA-AMPA-gated glutamate receptor channels depends on subunit composition. Science. 252:1991;851-853.
6. Hume R.I., Dingledine R., Heinemann S.F. Identification of a site in glutamate receptor subunits that controls calcium permeability. Science. 253:1991;1028-1031.
7. Dingledine R., Hume R., Heinemann S. Structural determinants of barium permeation and rectification in non-NMDA glutamate receptor channels. J Neurosci. 12:1992;4080-4087.
8. Stern-Bach Y., Bettler B., Hartley M., Sheppard P.O., O'Hara P.J., Heinemann S. Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron. 13:1994;1345-1357.
9. Massey SC. Cell types using glutamate as a neurotransmitter in the vertebrate retina. In: Osborne N, Chader J, editors. Progress in Retinal Research. Oxford: Pergamon Press, 1990.
10. Wässle H., Yamashita M., Greferath U., Grünert U., Müller F. The rod bipolar cell of the mammalian retina. Vis Neurosci. 7:1991;99-112.
11. Sarthy P.V., Lam D.M.-K. Isolated cells from a mammalian retina. Brain Res. 176:1979;208-212.
12. Huba R., Hofmann H.-D. Tetanus toxin binding to isolated and cultured rat retinal glial cells. Glia. 1:1988;156-164.
13. Greferath U., Grünert U., Wässle H. Rod bipolar cells in the mammalian retina show protein kinase C-like immunoreactivity. J Comp Neurol. 301:1990;433-442.
14. Marshall J., Molloy R., Moss G.W., Howe J.R., Hughes T.E. The jellyfish green fluorescent protein: a new tool for studying ion channel expression and function. Neuron. 14:1995;211-215.
15. Hughes T.E., Hermans-Borgmeyer I., Heinemann S. Differential expression of glutamate receptor genes (GluR1-5) in the rat retina. Vis Neurosci. 8:1992;49-55.
16. Müller F., Greferath U., Wässle H., Wisden W., Seeburg P. Glutamate receptor expression in the rat retina. Neurosci Lett. 138:1992;179-182.
17. Hamassaki-Britto D.E., Hermans-Borgmeyer I., Heinemann S., Hughes T.E. Expression of glutamate receptor genes in the mammalian retina: the localization of GluR1 through GluR7 mRNAs. J Neurosci. 13:1993;1888-1898.
18. Duvoisin R.M., Zhang C., Hamassaki-Britto D.E., Britto L.R. Changes in expression of glutamate receptor subunits following photoreceptor degeneration in the rd mouse retina. Neurosci Lett. 183:1995;83-86.
19. Peichl L., Gonzalez-Soriano J. Morphological types of horizontal cell in rodent retinae: a comparison of rat, mouse, gerbil, and guinea pig. Vis Neurosci. 11:1994;501-517.
20. De Jager P.L., Zuo J., Cook S.A., Heintz N. A new allele of the lurcher gene, lurcherJ. Mamm Genome. 8:1997;647-650.
21. Zuo J., De Jager P.L., Takahashi K.A., Jiang W., Linden D.J., Heintz N. Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature. 388:1997;769-773.
22. Sommer B., Kohler M., Sprengel R., Seeburg P.H. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 67:1991;11-19.
23. Burnashev N., Monyer H., Seeburg P.H., Sakmann B. Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron. 8:1992;189-198.
24. Higuchi M., Single F.N., Kohler M., Sommer B., Sprengel R., Seeburg P.H. RNA editing of AMPA receptor subunit GluR-B: a base-paired intron-exon structure determines position and efficiency. Cell. 75:1993;1361-1370.
25. Köhler M., Kornau H.-C., Seeburg P.H. The organization of the gene for the functionally dominant α-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid receptor subunit GluR-B*. J Biol Chem. 269:1994;17367-17370.
26. Herb A., Higuchi M., Sprengel R., Seeburg P.H. Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences. Proc Natl Acad Sci USA. 93:1996;1875-1880.
27. Sommer B., Keinanen K., Verdoorn T.A., Wisden W., Burnashev N., Herb A., Kohler M., Takagi T., Sakman B., Seeburg P.H. Flip and flop: A cell specific functional switch in glutamate-operated channels of the CNS. Science. 249:1990;1580-1585.
28. Hughes T.E. Are there ionotropic glutamate receptors on the rod bipolar cell of the mouse retina? Vis Neurosci. 14:1997;103-109.
29. Dong H., O'Brien R.J., Fung E.T., Lanahan A.A., Worley P.F., Huganir R.L. GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors [see comments]. Nature. 386:1997;279-284.
30. Hanks M., Wurst W., Anson-Cartwright L., Auerbach A.B., Joyner A.L. Rescue of the En-1 mutant phenotype by replacement of the En-1 with En-2. Science. 269:1995;679-682.
31. Wang Y., Schnegelsberg P.N.J., Dausman J., Jaenisch R. Functional redundance of the muscle-specific transcription factors Myf5 and myogenin. Nature. 379:1996;823-825.
32. Brandstatter J.H., Hartveit E., Sassoe-Pognetto M., Wässle H. Expression of NMDA and high-affinity kainate receptor subunit mRNAs in the adult rat retina. Eur J Neurosci. 6:1994;1100-1112.
33. Hartveit E., Brandstatter J.H., Sassoe-Pognetto M., Laurie D.J., Seeburg P.H., Wässle H. Localization and developmental expression of the NMDA receptor subunit NR2A in the mammalian retina. J Comp Neurol. 348:1994;570-582.
34. Watanabe M., Mishina M., Inoue Y. Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina. Brain Res. 634:1994;328-332.
35. Watanabe M., Mishina M., Inoue Y. Distinct spatiotemporal distributions of the N-Methyl-D-Aspartate receptor channel subunit mRNAs in the mouse cervical cord. J Comp Neurol. 345:1994;314-319.
36. Wyszynski M., Lin J., Rao A., Nigh E., Beggs A.H., Craig A.M., Sheng M. Competitive binding of alpha-actinin and calmodulin to the NMDA receptor. Nature. 385:1997;439-442.
37. Ehlers M.D., Tingley W.G., Huganir R.L. Regulated subcellular distribution of the NR1 subunit of the NMDA receptor. Science. 269:1995;1734-1737.
38. Brose N., Gasic G.P., Vetter D.E., Sullivan J.M., Heinemann S.F. Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1. J Biol Chem. 268:1993;22663-22671.
39. Puro D.G., Yuan J.P., Sucher N.J. Activation of NMDA receptor-channels in human retinal Muller glial cells inhibits inward-rectifying potassium currents. Vis Neurosci. 13:1996;319-326.
40. Wenzel A., Benke D., Mohler H., Fritschy J.M. N-Methyl-D-Aspartate receptors containing the Nr2d subunit in the retina are selectively expressed in rod bipolar cells. Neuroscience. 78:1997;1105-1112.
41. Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N., Nakanishi S. Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J Biol Chem. 268:1993;11868-11873.
42. Masu M., Iwakabe H., Tagawa Y., Miyoshi T., Yamashita M., Fukuda Y., Sasaki H., Hiroi K., Nakamura Y., Shigemoto R.et al. Specific deficit of the ON response in visual transmission by targeted disruption of the mGluR6 gene. Cell. 80:1995;757-765.
43. Yamashita M., Wässle H. Responses of rod bipolar cells isolated from the rat retina to the glutamate agonist 2-amino-4-phosphonobutyric acid (APB). J Neurosci. 11:1991;2372-2382.
44. Hartveit E. Membrane currents evoked by ionotropic glutamate receptor agonists in rod bipolar cells in the rat retinal slice preparation. J Neurophysiol. 76:1996;401-422.
45. Hille B. Ionic Channels of Excitable Membranes, 2nd ed. Sunderland, MA: Sinauer Associates, 1992.
46. Swaminathan R., Hoang C.P., Verkman A.S. Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion. Biophys J. 72:1997;1900-1907.
47. Yokoe H., Meyer T. Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement. Nat Biotechnol. 14:1996;1252-1256.
48. Barak L.S., Ferguson S.S.G., Zhang J., Martenson C., Meyer T., Caron M.G. Internal trafficking and surface mobility of a functionally intact B2-adrenergic receptor - green fluorescent protein conjugate. Mol Pharmacol. 51:1997;177-184.
49. Presley J.F., Cole N.B., Schroer T.A., Hirschberg K., Zaal K.J.M., Lippincottschwartz J. Er-to-golgi transport visualized in living cells. Nature. 389:1997;81-85.
50. Stya M., Axelrod D. Mobility and detergent extractability of acetylcholine receptors on cultured rat myotubes: a correlation. J Cell Biol. 97:1983;48-51.
51. Stya M., Axelrod D. Mobility of extrajunctional acetylcholine receptors on denervated adult muscle fibers. J Neurosci. 4:1984;70-74.
52. Molloy R.P., Hughes T.E. NMDAR1-GFP fusion protein expressed in P19 embryonal carcinoma cells. Soc Neurosci Abs. 23:1997;930.
53. Nomura A., Shigemoto R., Nakamura Y., Okamoto N., Mizuno N., Nakanishi S. Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell. 77:1994;361-369.
54. Iwakabe H., Katsuura G., Ishibashi C., Nakanishi S. Impairment of pupillary responses and optokinetic nystagmus in the Mglur6-deficient mouse. Neuropharmacology. 36:1997;135-143.
55. Li Y., Erzurumlu R.S., Chen C., Jhaveri S., Tonegawa S. Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell. 76:1994;427-437.
56. Brusa R., Zimmerman F., Koh D.-S., Feldmeyer D., Gass P., Seeburg P.H., Sprengel R. Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice. Science. 270:1995;1677-1680.
57. Tsien J.Z., Chen D.F., Gerber D., Tom C., Mercer E.H., Anderson D.J., Mayford M., Kandel E.R., Tonegawa S. Subregion- and cell type-restricted gene knockout in mouse brain [see comments]. Cell. 87:1996;1317-1326.
58. Tsien J.Z., Huerta P.T., Tonegawa S. The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory [see comments]. Cell. 87:1996;1327-1338.
59. Herskowitz I. Functional inactivation of genes by dominant negative mutations. Nature. 329:1987;219-222.
60. Wang K., Goldstein S. Subunit composition of mink potassium channels. Neuron. 14:1995;1303-1309.
61. Patil N., Cox D., Bhat D., Faham M., Myers R., Peterson A. A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation. Nat Genet. 11:1995;126-129.
62. Okabe M., Ikawa M., Kominami K., Nakanishi T., Nishimune Y. 'Green mice' as a source of ubiquitous green cells. FEBS Lett. 407:1997;313-319.
63. Zhuo L., Sun B., Zhang C.L., Fine A., Chiu S.Y., Messing A. Live astrocytes visualized by green fluorescent protein in transgenic mice. Dev Biol. 187:1997;36-42.
64. Nakanishi N., Axel R., Shneider N.A. Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors. Proc Natl Acad Sci USA. 89:1992;8552-8556.
65. Ueda Y., Iwakabe H., Masu M., Suzuki M., Nakanishi S. The mGluR6 5′ upstream transgene sequence directs a cell-specific and developmentally regulated expression in retinal rod and on-type cone bipolar cells. J Neurosci. 17:1997;3014-3023.