메뉴 건너뛰기




Volumn 217, Issue 1, 1996, Pages 230-241

Bicistronic and two-gene retroviral vectors for using MDR1 as a selectable marker and a therapeutic gene

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VECTOR;

EID: 0029913728     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0110     Document Type: Article
Times cited : (18)

References (51)
  • 1
    • 0025945901 scopus 로고
    • Internal initiation of translation in retroviral vectors carrying picornavirus 5′ nontranslated regions
    • Adam, M. A., Ramesh, N., Miller, A. D., and Osborne, W. R. A. (1991). Internal initiation of translation in retroviral vectors carrying picornavirus 5′ nontranslated regions. J. Virol. 65, 4985-4990.
    • (1991) J. Virol. , vol.65 , pp. 4985-4990
    • Adam, M.A.1    Ramesh, N.2    Miller, A.D.3    Osborne, W.R.A.4
  • 2
    • 0028255868 scopus 로고
    • Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector
    • Aran, J. M., Gottesman, M. M., and Pastan, I. (1994). Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector. Proc. Natl. Acad. Sci. USA 91, 3176-3180.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3176-3180
    • Aran, J.M.1    Gottesman, M.M.2    Pastan, I.3
  • 3
    • 0028064766 scopus 로고
    • Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor
    • Bodine, D. M., Seidel, N. E., Gale, M. S., Nienhuis, A. W., and Orlic, D. (1994). Efficient retrovirus transduction of mouse pluripotent hematopoietic stem cells mobilized into the peripheral blood by treatment with granulocyte colony-stimulating factor and stem cell factor. Blood 84, 1482-1491.
    • (1994) Blood , vol.84 , pp. 1482-1491
    • Bodine, D.M.1    Seidel, N.E.2    Gale, M.S.3    Nienhuis, A.W.4    Orlic, D.5
  • 4
    • 0027228422 scopus 로고
    • Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
    • Burns, J. C., Friedmann, T., Driever, W., Burrascano, M., and Yee, J.-K. (1993). Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA 90, 8033-8037.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8033-8037
    • Burns, J.C.1    Friedmann, T.2    Driever, W.3    Burrascano, M.4    Yee, J.-K.5
  • 5
    • 0025755463 scopus 로고
    • Expression of cathepsin L in human tumors
    • Chauhan, S. S., Goldstein, L. J., and Gottesman, M. M. (1991). Expression of cathepsin L in human tumors. Cancer Res. 51, 1478-1481.
    • (1991) Cancer Res. , vol.51 , pp. 1478-1481
    • Chauhan, S.S.1    Goldstein, L.J.2    Gottesman, M.M.3
  • 6
    • 0025327504 scopus 로고
    • Modulation of glutathione peroxidase expression by selenium: Effect on MCF-7 breast cancer cell transfectants expressing a cellular glutathione peroxidase cDNA and doxorubicin-resistant MCF-7 cells
    • Chu, F.-F., Esworthy, R. S., Akman, S., and Doroshow, J. H. (1990). Modulation of glutathione peroxidase expression by selenium: Effect on MCF-7 breast cancer cell transfectants expressing a cellular glutathione peroxidase cDNA and doxorubicin-resistant MCF-7 cells. Nucleic Acids Res. 18, 1531-1539.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 1531-1539
    • Chu, F.-F.1    Esworthy, R.S.2    Akman, S.3    Doroshow, J.H.4
  • 7
    • 0025089990 scopus 로고
    • Serial transplantation of methotrexate-resistant bone marrow: Protection of murine recipients from drug toxicity by progeny of transduced stem cells
    • Corey, C. A., DeSilva, A. D., Holland, C. A., and Williams, D. A. (1990). Serial transplantation of methotrexate-resistant bone marrow: Protection of murine recipients from drug toxicity by progeny of transduced stem cells. Blood 75, 337-343.
    • (1990) Blood , vol.75 , pp. 337-343
    • Corey, C.A.1    DeSilva, A.D.2    Holland, C.A.3    Williams, D.A.4
  • 8
    • 0029126007 scopus 로고
    • Transduction of NIH 3T3 cells with a retrovirus carrying both human MDR1 and glutathione Stransferase π produces broad-range multidrug resistance
    • Doroshow, J. H., Metz, M. Z., Matsumoto, L., Winter, K. A., Sakai, M., Muramatsu, M., and Kane, S. E. (1995). Transduction of NIH 3T3 cells with a retrovirus carrying both human MDR1 and glutathione Stransferase π produces broad-range multidrug resistance. Cancer Res 55, 4073-4078.
    • (1995) Cancer Res , vol.55 , pp. 4073-4078
    • Doroshow, J.H.1    Metz, M.Z.2    Matsumoto, L.3    Winter, K.A.4    Sakai, M.5    Muramatsu, M.6    Kane, S.E.7
  • 9
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D., and Mulligan, R. C. (1993). Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA 90, 3539-3543.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 10
    • 0028959499 scopus 로고
    • Use of the stress-inducible grp78/BiP promoter in targeting high level gene expression in fibrosarcoma in vivo
    • Gazit, G., Kane, S. E., Nichols, P., and Lee, A. S. (1995). Use of the stress-inducible grp78/BiP promoter in targeting high level gene expression in fibrosarcoma in vivo. Cancer Res. 55, 1660-1663.
    • (1995) Cancer Res. , vol.55 , pp. 1660-1663
    • Gazit, G.1    Kane, S.E.2    Nichols, P.3    Lee, A.S.4
  • 11
    • 0025997947 scopus 로고
    • The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos
    • Ghattas, I. R., Sanes, J. R., and Majors, J. E. (1991). The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol. Cell. Biol. 11, 5848-5859.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 5848-5859
    • Ghattas, I.R.1    Sanes, J.R.2    Majors, J.E.3
  • 12
    • 0028997079 scopus 로고
    • Resistance to taxol chemotherapy produced in mouse marrow cells by safety-modified retroviruses containing a human MDR-1 transcription unit
    • Hanania, E. G., Fu, S., Roninson, I., Zu, Z., Gottesman, M. M., and Deisseroth, A. B. (1995a). Resistance to taxol chemotherapy produced in mouse marrow cells by safety-modified retroviruses containing a human MDR-1 transcription unit. Gene Ther. 2, 279-284.
    • (1995) Gene Ther. , vol.2 , pp. 279-284
    • Hanania, E.G.1    Fu, S.2    Roninson, I.3    Zu, Z.4    Gottesman, M.M.5    Deisseroth, A.B.6
  • 13
    • 0029051148 scopus 로고
    • Chemotherapy resistance to taxol in clonogenic progenitor cells following transduction of CD34 selected marrow and peripheral blood cells with a retrovirus which contains the MDR-1 chemotherapy resistance gene
    • Hanania, E. G., Fu, S., Zu, Z., Hegewisch-Becker, S., Korbling, M., Andreeff, M., Mechetner, E., Roninson, I., Giles, R., Berenson, R., Heimfeld, S., and Deisseroth, A. B. (1995b). Chemotherapy resistance to taxol in clonogenic progenitor cells following transduction of CD34 selected marrow and peripheral blood cells with a retrovirus which contains the MDR-1 chemotherapy resistance gene. Gene Ther. 2, 285-294.
    • (1995) Gene Ther. , vol.2 , pp. 285-294
    • Hanania, E.G.1    Fu, S.2    Zu, Z.3    Hegewisch-Becker, S.4    Korbling, M.5    Andreeff, M.6    Mechetner, E.7    Roninson, I.8    Giles, R.9    Berenson, R.10    Heimfeld, S.11    Deisseroth, A.B.12
  • 14
    • 0026098571 scopus 로고
    • Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position
    • Hoeben, R. C., Migchielsen, A. A. J., van der Jagt, R. C. M., van Ormondt, H., and van der Eb, A. J. (1991). Inactivation of the Moloney murine leukemia virus long terminal repeat in murine fibroblast cell lines is associated with methylation and dependent on its chromosomal position. J. Virol. 65, 904-912.
    • (1991) J. Virol. , vol.65 , pp. 904-912
    • Hoeben, R.C.1    Migchielsen, A.A.J.2    Van Der Jagt, R.C.M.3    Van Ormondt, H.4    Van Der Eb, A.J.5
  • 15
    • 0019519189 scopus 로고
    • Chromosomal position and activation of retroviral genomes inserted into the germ line of mice
    • Jaenisch, R., Jahner, D., Nobis, P., Simon, I., Lohler, J., Harbers, K., and Grotkopp, D. (1981). Chromosomal position and activation of retroviral genomes inserted into the germ line of mice. Cell 24, 519-529.
    • (1981) Cell , vol.24 , pp. 519-529
    • Jaenisch, R.1    Jahner, D.2    Nobis, P.3    Simon, I.4    Lohler, J.5    Harbers, K.6    Grotkopp, D.7
  • 16
    • 0023795613 scopus 로고
    • Use of a cloned multidrug resistance gene for coamplification and overproduction of major excreted protein, a transformation-regulated secreted acid protease
    • Kane, S. E., Troen, B. R., Gal, S., Ueda, K., Pastan, I., and Gottesman, M. M. (1988). Use of a cloned multidrug resistance gene for coamplification and overproduction of major excreted protein, a transformation-regulated secreted acid protease. Mol. Cell. Biol. 8, 3316-3321.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3316-3321
    • Kane, S.E.1    Troen, B.R.2    Gal, S.3    Ueda, K.4    Pastan, I.5    Gottesman, M.M.6
  • 17
    • 0024787142 scopus 로고
    • A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells
    • Kane, S. E., Reinhard, D. H., Fordis, C. M., Pastan, I., and Gottesman, M. M. (1989). A new vector using the human multidrug resistance gene as a selectable marker enables overexpression of foreign genes in eukaryotic cells. Gene 84, 439-446.
    • (1989) Gene , vol.84 , pp. 439-446
    • Kane, S.E.1    Reinhard, D.H.2    Fordis, C.M.3    Pastan, I.4    Gottesman, M.M.5
  • 18
    • 0025040859 scopus 로고
    • Genetic basis of multidrug resistance of tumor cells
    • Kane, S. E., Pastan, I., and Gottesman, M. M. (1990). Genetic basis of multidrug resistance of tumor cells. J. Bioenerg. Biomembr. 22, 593-618.
    • (1990) J. Bioenerg. Biomembr. , vol.22 , pp. 593-618
    • Kane, S.E.1    Pastan, I.2    Gottesman, M.M.3
  • 19
    • 0028340408 scopus 로고
    • Development of a retroviral construct containing a human mutated dihydrofolate reductase cDNA for hematopoietic stem cell transduction
    • Li, M.-X., Banerjee, D., Zhao, S.-C., Schweitzer, B. I., Mineishi, S., Gilboa, E., and Bertino, J. R. (1994). Development of a retroviral construct containing a human mutated dihydrofolate reductase cDNA for hematopoietic stem cell transduction. Blood 83, 3403-3408.
    • (1994) Blood , vol.83 , pp. 3403-3408
    • Li, M.-X.1    Banerjee, D.2    Zhao, S.-C.3    Schweitzer, B.I.4    Mineishi, S.5    Gilboa, E.6    Bertino, J.R.7
  • 20
    • 0023432013 scopus 로고
    • Retrovirus-mediated gene transfer of human adenosine deaminase: Expression of functional enzyme in murine hematopoietic cells in vivo
    • Lim, B., Williams, D. A., and Orkin, S. H. (1987). Retrovirus-mediated gene transfer of human adenosine deaminase: Expression of functional enzyme in murine hematopoietic cells in vivo. Mol. Cell. Biol. 7, 3459-3465.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3459-3465
    • Lim, B.1    Williams, D.A.2    Orkin, S.H.3
  • 21
    • 0028607647 scopus 로고
    • Delayed morbidity and mortality of albumin/SV40 T-antigen transgenic mice after insertion of an α-fetoprotein/herpes virus thymidine kinase transgene and treatment with ganciclovir
    • Macri, P., and Gordon, J. W. (1994). Delayed morbidity and mortality of albumin/SV40 T-antigen transgenic mice after insertion of an α-fetoprotein/herpes virus thymidine kinase transgene and treatment with ganciclovir. Human Gene Ther. 5, 175-182.
    • (1994) Human Gene Ther. , vol.5 , pp. 175-182
    • Macri, P.1    Gordon, J.W.2
  • 22
    • 0023871422 scopus 로고
    • A safe packaging line for gene transfer: Separating viral genes on two different plasmids
    • Markowitz, D., Goff, S., and Bank, A. (1988a). A safe packaging line for gene transfer: Separating viral genes on two different plasmids. J. Virol. 62, 1120-1124.
    • (1988) J. Virol. , vol.62 , pp. 1120-1124
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 23
    • 0024239024 scopus 로고
    • Construction and use of a safe and efficient amphotropic packaging cell line
    • Markowitz, D., Goff, S., and Bank, A. (1988b). Construction and use of a safe and efficient amphotropic packaging cell line. Virology 167, 400-406.
    • (1988) Virology , vol.167 , pp. 400-406
    • Markowitz, D.1    Goff, S.2    Bank, A.3
  • 24
    • 0023131851 scopus 로고
    • Human purine nucleoside phosphorylase and adenosine deaminase: Gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses
    • McIvor, R. S., Johnson, M. J., Miller, A. D., Pitts, S., Williams, S. R., Valerio, D., Martin, D. W., and Verma, I. M. (1987). Human purine nucleoside phosphorylase and adenosine deaminase: Gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses. Mol. Cell. Biol. 7, 838-846.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 838-846
    • McIvor, R.S.1    Johnson, M.J.2    Miller, A.D.3    Pitts, S.4    Williams, S.R.5    Valerio, D.6    Martin, D.W.7    Verma, I.M.8
  • 25
    • 0024507854 scopus 로고
    • Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein
    • Meric, C., and Goff, S. P. (1989). Characterization of Moloney murine leukemia virus mutants with single-amino-acid substitutions in the Cys-His box of the nucleocapsid protein. J. Virol. 63, 1558-1568.
    • (1989) J. Virol. , vol.63 , pp. 1558-1568
    • Meric, C.1    Goff, S.P.2
  • 26
    • 0029015066 scopus 로고
    • Harvey murine sarcoma virus/MDR1 retroviral vectors: Efficient virus production and foreign gene transduction using MDR1 as a selectable marker
    • Metz, M. Z., Best, D. M., and Kane, S. E. (1995). Harvey murine sarcoma virus/MDR1 retroviral vectors: Efficient virus production and foreign gene transduction using MDR1 as a selectable marker. Virology 208, 634-643.
    • (1995) Virology , vol.208 , pp. 634-643
    • Metz, M.Z.1    Best, D.M.2    Kane, S.E.3
  • 27
    • 0026089343 scopus 로고
    • Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance
    • Mickisch, G. H., Merlino, G. T., Galski, H., Gottesman, M. M., and Pastan, I. (1991). Transgenic mice that express the human multidrug-resistance gene in bone marrow enable a rapid identification of agents that reverse drug resistance. Proc. Natl. Acad. Sci. USA 88, 547-551.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 547-551
    • Mickisch, G.H.1    Merlino, G.T.2    Galski, H.3    Gottesman, M.M.4    Pastan, I.5
  • 28
    • 0025834275 scopus 로고
    • Construction and properties of retrovirus packaging cells based on Gibbon ape leukemia virus
    • Miller, A. D., Garcia, J. V., von Suhr, N., Lynch, C. M., Wilson, C., and Eden, M. V. (1991). Construction and properties of retrovirus packaging cells based on Gibbon ape leukemia virus. J. Virol. 65, 2220-2224.
    • (1991) J. Virol. , vol.65 , pp. 2220-2224
    • Miller, A.D.1    Garcia, J.V.2    Von Suhr, N.3    Lynch, C.M.4    Wilson, C.5    Eden, M.V.6
  • 29
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • Miller, A. D., and Rosman, G. J. (1989). Improved retroviral vectors for gene transfer and expression. BioTechniques 7, 980-990.
    • (1989) BioTechniques , vol.7 , pp. 980-990
    • Miller, A.D.1    Rosman, G.J.2
  • 30
    • 0025279872 scopus 로고
    • Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection
    • Miller, D. G., Adam, M. A., and Miller, A. D. (1990). Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol. Cell. Biol. 10, 4239-4242.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 4239-4242
    • Miller, D.G.1    Adam, M.A.2    Miller, A.D.3
  • 31
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa, H., Yamamura, K.-I., and Miyazaki, J.-I. (1991). Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.-I.2    Miyazaki, J.-I.3
  • 32
    • 0025976935 scopus 로고
    • Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
    • Palmer, T. D., Rosman, G. J., Osborne, W. R. A., and Miller, A. D. (1991). Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. Proc. Natl. Acad. Sci. USA 88, 1330-1334.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1330-1334
    • Palmer, T.D.1    Rosman, G.J.2    Osborne, W.R.A.3    Miller, A.D.4
  • 33
    • 0013508682 scopus 로고
    • A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells
    • Pastan, I., Gottesman, M. M., Ueda, K., Lovelace, E., Rutherford, A. V., and Willingham, M. C. (1988). A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells. Proc. Natl. Acad. Sci. USA 85, 4486-4490.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4486-4490
    • Pastan, I.1    Gottesman, M.M.2    Ueda, K.3    Lovelace, E.4    Rutherford, A.V.5    Willingham, M.C.6
  • 34
    • 0021036529 scopus 로고
    • Homologous sequences other than insertion elements can serve as recombination sites in plasmid drug resistance gene amplification
    • Peterson, B. C., and Rownd, R. H. (1983). Homologous sequences other than insertion elements can serve as recombination sites in plasmid drug resistance gene amplification. J. Bacteriol. 156, 177-185.
    • (1983) J. Bacteriol. , vol.156 , pp. 177-185
    • Peterson, B.C.1    Rownd, R.H.2
  • 36
    • 0027172622 scopus 로고
    • Retroviral vectors displaying functional antibody fragments
    • Russell, S. J., Hawkins, R. E., and Winter, G. (1993). Retroviral vectors displaying functional antibody fragments. Nucleic Acids Res. 21, 1081-1085.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1081-1085
    • Russell, S.J.1    Hawkins, R.E.2    Winter, G.3
  • 38
    • 0026637623 scopus 로고
    • Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1
    • Sorrentino, B. P., Brandt, S. J., Bodine, D., Gottesman, M., Pastan, I., Cline, A., and Nienhuis, A. W. (1992). Selection of drug-resistant bone marrow cells in vivo after retroviral transfer of human MDR1. Science 257, 99-103.
    • (1992) Science , vol.257 , pp. 99-103
    • Sorrentino, B.P.1    Brandt, S.J.2    Bodine, D.3    Gottesman, M.4    Pastan, I.5    Cline, A.6    Nienhuis, A.W.7
  • 39
    • 0029058758 scopus 로고
    • Expression of retroviral vectors containing the human MDR1 cDNA in hematopoietic cells of transplanted mice
    • Sorrentino, B. P., McDonagh, K. T., Woods, D., and Orlic, D. (1995). Expression of retroviral vectors containing the human MDR1 cDNA in hematopoietic cells of transplanted mice. Blood 86, 491-501.
    • (1995) Blood , vol.86 , pp. 491-501
    • Sorrentino, B.P.1    McDonagh, K.T.2    Woods, D.3    Orlic, D.4
  • 40
    • 0028229767 scopus 로고
    • Efficient expression of drug-selectable genes in retroviral vectors under control of an internal ribosome entry site
    • Sugimoto, Y., Aksentijevich, I., Gottesman, M. M., and Pastan, I. (1994). Efficient expression of drug-selectable genes in retroviral vectors under control of an internal ribosome entry site. Bio/Technology 12, 694-698.
    • (1994) Bio/Technology , vol.12 , pp. 694-698
    • Sugimoto, Y.1    Aksentijevich, I.2    Gottesman, M.M.3    Pastan, I.4
  • 41
    • 0028821345 scopus 로고
    • Retroviral coexpression of a multidrug resistance gene (MDR1) and human α-galactosidase A for gene therapy of Fabry disease
    • Sugimoto, Y., Aksentijevich, I., Murray, G. J., Brady, R. Q., Pastan, I., and Gottesman, M. M. (1995a). Retroviral coexpression of a multidrug resistance gene (MDR1) and human α-galactosidase A for gene therapy of Fabry disease. Hum. Gene Ther. 6, 905-915.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 905-915
    • Sugimoto, Y.1    Aksentijevich, I.2    Murray, G.J.3    Brady, R.Q.4    Pastan, I.5    Gottesman, M.M.6
  • 42
    • 0028986284 scopus 로고
    • Coexpression of a multidrug-resistance gene (MDR1) and herpes simplex virus thymidine kinase gene as part of a bicistronic messenger RNA in a retrovirus vector allows selective killing of MDR1-transduced cells
    • Sugimoto, Y., Hrycyna, C. A., Aksentijevich, I., Pastan, I., and Gottesman, M. M. (1995b). Coexpression of a multidrug-resistance gene (MDR1) and herpes simplex virus thymidine kinase gene as part of a bicistronic messenger RNA in a retrovirus vector allows selective killing of MDR1-transduced cells. Clin. Cancer Res. 1, 447-457.
    • (1995) Clin. Cancer Res. , vol.1 , pp. 447-457
    • Sugimoto, Y.1    Hrycyna, C.A.2    Aksentijevich, I.3    Pastan, I.4    Gottesman, M.M.5
  • 44
    • 0027954398 scopus 로고
    • A small and efficient dimerization/packaging signal of rat VL30 RNA and its use in murine leukemia virus-VL30-derived vectors for gene transfer
    • Torrent, C., Gabus, C., and Darlix, J-L. (1994). A small and efficient dimerization/packaging signal of rat VL30 RNA and its use in murine leukemia virus-VL30-derived vectors for gene transfer. J. Virol. 68, 661-667.
    • (1994) J. Virol. , vol.68 , pp. 661-667
    • Torrent, C.1    Gabus, C.2    Darlix, J.-L.3
  • 45
    • 0025982858 scopus 로고
    • Downstream sequences mediate induction of the mouse cathepsin L promoter by phorbol esters
    • Troen, B. R., Chauhan, S. S., Ray, D., and Gottesman, M. M. (1991). Downstream sequences mediate induction of the mouse cathepsin L promoter by phorbol esters. Cell Growth Differentiation 2, 23-31.
    • (1991) Cell Growth Differentiation , vol.2 , pp. 23-31
    • Troen, B.R.1    Chauhan, S.S.2    Ray, D.3    Gottesman, M.M.4
  • 46
    • 0008632564 scopus 로고
    • Expression of a full-length cDNA for the human "MDR1"gene confers resistance to colchicine, doxorubicin, and vinblastine
    • Ueda, K., Cardarelli, C., Gottesman, M. M., and Pastan, I. (1987). Expression of a full-length cDNA for the human "MDR1"gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc. Natl. Acad. Sci. USA 84, 3004-3008.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3004-3008
    • Ueda, K.1    Cardarelli, C.2    Gottesman, M.M.3    Pastan, I.4
  • 48
    • 0023595325 scopus 로고
    • Epidermal growth factor-dependent transformation by a human EGF receptor proto-oncogene
    • Velu, T. J., Beguinot, L., Vass, W. C., Willingham, M. C., Merlino, G. T., Pastan, I., and Lowy, D. R. (1987). Epidermal growth factor-dependent transformation by a human EGF receptor proto-oncogene. Science 238, 1408-1410.
    • (1987) Science , vol.238 , pp. 1408-1410
    • Velu, T.J.1    Beguinot, L.2    Vass, W.C.3    Willingham, M.C.4    Merlino, G.T.5    Pastan, I.6    Lowy, D.R.7
  • 49
    • 0027477387 scopus 로고
    • In vitro and in vivo targeting of gene expression to melanoma cells
    • Vile, R. G., and Hart, I. R. (1993). In vitro and in vivo targeting of gene expression to melanoma cells. Cancer Res. 53, 962-967.
    • (1993) Cancer Res. , vol.53 , pp. 962-967
    • Vile, R.G.1    Hart, I.R.2
  • 51
    • 0025702622 scopus 로고
    • Efficient incorporation of human CD4 protein into avian leukosis virus particles
    • Young, J. A. T., Bates, P., Willert, K., and Varmus, H. E. (1990). Efficient incorporation of human CD4 protein into avian leukosis virus particles. Science 250, 1421-1423.
    • (1990) Science , vol.250 , pp. 1421-1423
    • Young, J.A.T.1    Bates, P.2    Willert, K.3    Varmus, H.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.