Acetylcholine is a vasodilator of porcine skeletal muscle arteries

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Volumn 120, Issue 2, 1998, Pages 345-354

  Harold Laughlin, M ^a   M McAllister, Richard ^a   Jasperse, Jeffery L ^a   Hitchcock, Lora S ^a   Bonagura, John D ^a  

^a the Dalton C   (United States)

Author keywords

A23187; Bradykinin; Doppler ultrasound; Endothelium; Indomethacin; L Arginine; L NAME; Nitric oxide synthase; Nitroprusside; Vascular smooth muscle

Indexed keywords

ACETYLCHOLINE;

ANIMAL TISSUE; ARTERY DILATATION; ARTERY RESISTANCE; ARTICLE; BLOOD VESSEL DIAMETER; MUSCLE BLOOD FLOW; NONHUMAN; OXIDATION; SKELETAL MUSCLE; SWINE; TRICEPS BRACHII MUSCLE; VASCULAR SMOOTH MUSCLE;

EID: 0032075780     PISSN: 10956433     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1095-6433(98)10035-1     Document Type: Article

References (24)

1. Armstrong R.B., Delp M.D., Golian E.F., Laughlin M.H. Distribution of blood flow in muscles of miniature swine during exercise. J Appl Physiol. 62:1987;1285-1298.
2. Avasthi P.S., Greene E.R., Voyles W.F., Eldridge M.W. A comparison of echo-Doppler and electromagnetic renal blood flow measurements. J Ultrasound Med. 3:1984;213-218.
3. Cowan C.L., McKenzie J.E. Cholinergic regulation of resting coronary blood flow in domestic swine. Am J Physiol. 259:1990;H109-H115.
4. Delp M.D., McAllister R.M., Laughlin M.H. Exercise training alters endothelium-dependent vasoreactivity of rat abdominal aorta. J Appl Physiol. 75:1993;1354-1363.
5. Feletou M, Teisseire B. Vascular pharmacology of the micropig: importance of the endothelium. In: Swindle MS, editor. Swine Models in Biomedical Research. Ames: Iowa State University Press, 1992:74-95.
6. Furchgott R.F., Zawadzki J.V. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 288:1980;373-376.
7. Gill R.W. Measurement of blood flow by ultrasound: accuracy and sources of error. Ultrasound Med Biol. 11:1985;625-641.
8. 86Rb efflux from isolated endothelial cells. Br J Pharmacol. 79:1983;531-542.
9. Green D.J., O'Driscoll G., Blanksby B.A., Taylor R.T. Control of skeletal muscle blood flow during dynamic exercise: contribution of endothelium-derived nitric oxide. Sports Med. 21:1996;119-146.
10. Komori K., Shimokawa H., Vanhoutte P.M. Hypercholesterolemia impairs endothelium-dependent relaxations to aggregating platelets in porcine iliac arteries. J Vasc Surg. 10:1989;318-325.
11. Kuo L., Chilian W.M., Davis M.J., Laughlin M.H. Endotoxin impairs flow-induced vasodilation of porcine coronary arterioles. Am J Physiol. 262:1992;H1838-H1845.
12. Kuo L., Chilian W.M., Davis M.J. Coronary arteriolar myogenic response is independent of endothelium. Circ Res. 66:1990;860-866.
13. Linnik M.D., Lee T.J. Effect of hemoglobin on neurogenic responses and cholinergic parameters in porcine cerebral arteries. J Cereb Blood Flow Metab. 9:1989;219-225.
14. Luscher TF, Vanhoutte PM. Heterogeneity and chronic modulation. In: The Endothelium: Modulator of Cardiovascular Function. Boca Raton, FL: CRC Press, 1990:99-110.
15. McAllister R.M., Kimani J.K., Webster J.L., Parker J.L., Laughlin M.H. Effects of exercise training on responses of peripheral and visceral arteries in swine. J Appl Physiol. 80:1996;216-225.
16. McAllister R.M. Endothelial-mediated control of coronary and skeletal muscle blood flow during exercise. Med Sci Sports Exerc. 27:1995;1122-1124.
17. McAllister R.M., Hirai T., Musch T.I. Contribution of endothelium-derived nitric oxide (EDNO) to the skeletal muscle blood flow response to exercise. MedSci. Sports Exerc. 27:1995;1145-1151.
18. Oltman C.L., Parker J.L., Adams H.R., Laughlin M.H. Effects of exercise training on vasomotor reactivity of porcine coronary arteries. Am J Physiol. 263:1992;H372-H32.
19. Oltman C.L., Parker J.L., Laughlin M.H. Endothelium-dependent vasodilation of proximal coronary arteries from exercise trained pigs. J Appl Physiol. 79:1995;33-40.
20. Parker J.L., Mattox M.L., Laughlin M.H. Contractile responsiveness of coronary arteries from exercise-trained rats. J Appl Physiol. 83:1997;434-443.
21. Shoemaker J.K., Pozeg Z.I., Hughson R.L. Forearm blood flow by Doppler ultrasound during rest and exercise: tests of day-to-day repeatability. Med Sci Sports Exerc. 28:1996;1144-1149.
22. Steel RGD, Torrie JH. Principles and Procedures of Statistics. New York: McGraw-Hill, 1960.
23. Sun D., Huang A., Koller A., Kaley G. Short-term exercise activity enhances endothelial NO synthesis in skeletal muscle arterioles of rats. J Appl Physiol. 76:1994;2241-2247.
24. Zuckerman S.L., Armstead W.M., Hsu P., Shibata M., Leffler C.W. Age dependence of cerebrovascular response mechanisms in domestic pigs. Am J Physiol. 271:1996;H535-H540.