Flavonoid-induced ability of minimally modified low-density lipoproteins to support lymphocyte proliferation

Biochemical Pharmacology

Volumn 55, Issue 7, 1998, Pages 1125-1129

  Carrero, Pilar ^a   Ortega, Henar ^a   Martínez Botas, Javier ^a   Gómez Coronado, Diego ^a   Lasunción, Miguel A ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Cell proliferation; Flavonoids; Lipoperoxidation; Lymphocyte; Minimally modified LDL; Wine

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; FLAVONOID; LOW DENSITY LIPOPROTEIN; MEVINOLIN; QUERCETIN;

ARTICLE; BEVERAGE; CELL GROWTH; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; GRAPE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LIPID PEROXIDATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL;

ANTIOXIDANTS; CELL LINE; CELL SURVIVAL; DNA; FLAVONOIDS; HUMANS; LIPOPROTEINS, LDL; LYMPHOCYTE ACTIVATION; QUERCETIN; ROSALES; WINE;

EID: 0032055621     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00635-7     Document Type: Article

References (22)

1. Witztum J.L. The oxidation hypothesis of atherosclerosis. Lancet. 344:1994;793-795.
2. Chisolm G.M. Cytotoxicity of oxidized lipoproteins. Curr Opin Lipidol. 2:1991;311-316.
3. Palinski W., Rosenfeld M.E., Ylä-Herttuala S., Gurtner G.C., Socher S.S., Butler S.W., Parthasarathy S., Carew T.E., Steinberg D., Witztum J.L. Low-density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci USA. 86:1989;1372-1376.
4. Camejo G., Hurt-Camejo E., Rosengren B., Wiklund O., López F., Bondjers G. Modification of copper-catalyzed oxidation of low-density lipoprotein by proteoglycans and glycosaminglycans. J Lipid Res. 32:1991;1983-1991.
5. Ylä-Herttuala S., Palinski W., Rosenfeld M.E., Parthasarathy S., Carew T.E., Butler S., Witztum J.L., Steinberg D. Evidence for the presence of oxidatively modified low-density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest. 84:1989;1086-1095.
6. Stemme S., Faber B., Holm J., Wiklund O., Witzum J.L., Hansson G.K. T lymphocytes from human atherosclerotic plaques recognize oxidized low-density lipoprotein. Proc Natl Acad Sci USA. 92:1995;3893-3897.
7. Berliner J., Territo M.C., Sevanian A., Ramin S., Kim J.A., Bamshad B., Esterson M., Fogelman A.M. Minimally modified low-density lipoprotein stimulates monocyte endothelial interactions. J Clin Invest. 85:1990;1260-1266.
8. De Whalley C.V., Rankin S.M., Hoult J.R.S., Jessup W., Leake D.S. Flavonoids inhibit the oxidative modification of LDL by macrophages. Biochem Pharmacol. 39:1990;1743-1750.
9. Rice-Evans C.A., Miller N.J. Antioxidant activities of flavonoids as bioactive components of food. Biochem Soc Trans. 24:1996;790-795.
10. Chung B.H., Segrest J.P., Ray M.J., Brunzell J.D., Hokanson J.E., Krauss R.M., Beaudrie K., Cone J.T. Single vertical spin density gradient ultracentrifugation. Segrest J.P., Albers J.J. Methods in Enzymology, vol 28, Plasma Lipoproteins, part A, Preparation, Structure, and Molecular Biology. 1986;181-209 Academic Press, Orlando, FL.
11. Lasunción M.A., Teruel J.L., Alvarez J.J., Carrero P., Ortuño J., Gómez-Coronado D. Changes in lipoprotein(a), LDL-cholesterol and apolipoprotein B in homozygous familial hypercholesterolaemic patients treated with dextran sulfate LDL-apheresis. Eur J Clin Invest. 23:1993;819-826.
12. Suárez Y., Martínez-Botas J., Ortega H., Ferruelo A.J., Gómez-Coronado D., Teruel J.L., Lasunción M.A. Determinación de la actividad del receptor de LDL en linfocitos mediante citometría de flujo para el diagnóstico de la hipercolesterolemia familiar. Clin Invest Arterios. 9:1997;47-54.
13. Cuthbert J.A., Lipsky P.E. Inhibition by 6-fluoromevalonate demonstrates that mevalonate or one of the mevalonate phosphates is necessary for lymphocyte proliferation. J Biol Chem. 265:1990;18568-18575.
14. Wieland E., Schettle V., Diedrich F., Schuff-Werner P., Oellerich M. Determination of lipid hydroperoxides in serum iodometry and high-performance liquid chromatography (HPLC) compared. Eur J Clin Chem Clin Biochem. 30:1992;363-369.
15. Wallin B., Rosengren B., Shertzer H.G., Camejo G. Lipoprotein oxidation and measurement of thiobarbituric acid reacting substances formation in a single microtiter plate its use for evaluation of antioxidants . Anal Biochem. 208:1993;10-15.
16. Singleton V.L., Rossi J.A. Colorimetry of total phenolics with phosphomolybdic and phosphotungstic acid reagents. Amer J Enol Vitic. 16:1965;144-158.
17. Sánchez-Quesada J.L., Ortega H., Payés-Romero A., Serrat-Serrat J., González-Sastre F., Lasunción M.A., Ordóñez-Llanos J. LDL from aerobically trained subjects shows higher resistance to oxidative modification than LDL from sedentary subjects. Relation with the antioxidant content. Atherosclerosis. 132:1997;207-213.
18. Babiy A.V., Gebicki J.M., Sullivan D.R. Vitamin E content and low-density lipoprotein oxidizability induced by free radicals. Atherosclerosis. 81:1990;175-182.
19. Avila M.A., Velasco J.A., Cansado, Notario V. Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468. Cancer Res. 54:1994;2424-2428.
20. Pérez-Sala D., Mollinedo F. Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells. Biochem Biophys Res Commun. 199:1994;1209-1215.
21. Nègre-Salvayre A., Salvayre R. Quercetin prevents the cytotoxicity of oxidized LDL on lymphoid cell lines. Free Radic Biol Med. 12:1992;101-106.
22. Hollman P.C.H., de Vries J.H.M., van Leeuwen S.D., Mengelers M.J.B., Katan M.B. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am J Clin Nutr. 62:1995;1276-1282.