Clonal analysis of intrahepatic B cells from HCV-infected patients with and without mixed cryoglobulinemia

Journal of Immunology

Volumn 160, Issue 7, 1998, Pages 3594-3601

  Sansonno, Domenico ^a   De Vita, Salvatore ^b   Iacobelli, Anna Rina ^a   Cornacchiulo, Vito ^a   Boiocchi, Mauro ^b   Dammacco, Franco ^a  

^a UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^b CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; B LYMPHOCYTE; CRYOGLOBULINEMIA; GENE REARRANGEMENT; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; PRIORITY JOURNAL; VIRUS CELL INTERACTION;

ADULT; AGED; B-LYMPHOCYTES; CLONE CELLS; CRYOGLOBULINEMIA; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; IN SITU HYBRIDIZATION; LIVER; MALE; MIDDLE AGED; RHEUMATOID FACTOR; RNA, VIRAL; SEQUENCE ANALYSIS, DNA;

EID: 0032055586     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Choo, Q. L., A. J. Weiner, L. R. Overby, G. Kuo, M. Houghton, and D. W. Bradley. 1990. Hepatitis C virus: the major causative agent of viral non-A, non-B hepatitis. Br. Med. Bull. 46:423.
2. Alter, H. J. 1995. To C or not to C: these are the questions. Blood 85:1681.
3. Missale, G., R. Bertoni, V. Lamonaca, A. Valli, M. Massari, C. Mori, M. G. Rumi, M. Houghton, F. Fiaccadori, and C. Ferrari. 1996. Different clinical behaviors of acute and chronic hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. J. Clin. Invest. 98:706.
4. Muratori, L., D. Gibellini, M. Lenzi, M. Cataleta, P. Muratori, M. C. Morelli, and F. B. Bianchi. 1996. Quantification of hepatitis C virus-infected peripheral blood mononuclear cells by in situ reverse transcriptase-polymerase chain reaction. Blood 88:2768.
5. Sansonno, D., S. De Vita, V. Comacchiulo, A. Carbone, M. Boiocchi, and F. Dammacco. 1996. Detection and distribution of hepatitis C virus-related proteins in lymph nodes of patients with type II mixed cryoglobulinemia and neoplastic or non-neoplastic lymphoproliferation. Blood 88:4638.
6. Fujii, K., K. Hino, M. Okazaki, M. Okuda, S. Kondoh, and K. Okita. 1996. Differences in hypervariable region 1 quasispecies of hepatitis C virus between human serum and peripheral blood mononuclear cells. Biochem. Biophys. Res. Commun. 225:771.
7. Liu Y. J., and J. Banchereau. 1996. The paths and molecular controls of peripheral B-cell development. Immunologist 4:55.
8. Trainor, K. J., M. J. Brisco, C. J. Story, and A. A. Morley. 1990. Monoclonality in B-lymphoproliferative disorders detected at the DNA level. Blood 75:2220.
9. Diss, T. C., H. Peng, A. C. Wotherspoon, P. G. Isaacson, and L. Pan. 1993. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J. Pathol. 169:291.
10. Franzin, F., D. G. Efremov, G. Pozzato, P. Tulissi, F. Batista, and O. R. Burrone. 1995. Clonal B-cell expansions in peripheral blood of HCV-infected patients. Br. J. Haematol. 90:548.
11. McCarthy, K. P., J. P. Sloane, and L. M. Wiedmann. 1990. Rapid method for distinguishing clonal from polyclonal B cell populations in surgical biopsy specimens. J. Clin. Pathol. 43:429.
12. Agnello, V. 1995. The aetiology of mixed cryoglobulinaemia associated with hepatitis C virus infection. Scand. J. Immunol. 42:1.
13. Monteverde, A., E. Sabattini, S. Poggi, M. Ballarè, M. C. Bertoncelli, A. De Vivo, A. Briskomatis, G. Roncador, B. Falini, and S. A. Pileri. 1996. Bone marrow findings further support the hypothesis that essential mixed cryoglobulinemia type II is characterized by a monoclonal B-cell proliferation. Leuk. Lymphoma 20:119.
14. Dammacco, F., D. Sansonno, V. Cornacchiulo, C. Mennuni, R. Carbone, G. Lauletta, A. R. lacobelli, and R. Rizzi. 1993. Hepatitis C virus infection and mixed cryoglobulinemia: a striking association. Int. J. Clin. Lab. Res. 23:45.
15. Mosnier, J. F., C. Degott, P. Marcellin, D. Hénin, S. Erlinger, and J. P. Benhamou. 1993. The intraportal lymphoid nodule and its environment in chronic active hepatitis C: an immunohistochemical study. Hepatology 17:366.
16. Negro, F., D. Pacchioni, Y. Shimizu, R. H. Miller, G. Bussolati, R. H. Purcell, and F. Bonino. 1992. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proc. Natl. Acad. Sci. USA 89:2247.
17. Carbone, A., V. De Re, A. Gloghini, R. Volpe, M. Tavian, U. Tirelli, S. Monfardini, and M. Boiocchi. 1989. Immunoglobulin and T cell receptor gene rearrangements and in situ immunophenotyping in lymphoproliferative disorders. Virchows Arch. A Pathol. Anat. Histol. 414:223.
18. De Vita, S., M. Boiocchi, D. Sorrentino, A. Carbone, C. Avellini, R. Dolcetti, A. Marzotto, A. Gloghini, E. Bartoli, C. A. Beltrami, and G. F. Ferraccioli. 1997. Characterization of prelymphomatous stages of B-cell lymphoproliferation in Sjögren's syndrome. Arthritis Rheum. 40:318.
19. Ramasamy, I., M. Brisco, and A. Morley. 1992. Improved PCR method for detecting monoclonal immunoglobulin heavy chain rearrangement in B cell neoplasms. J. Clin. Pathol 45:770.
20. Sansonno, D., A. R. Iacobelli, V. Cornacchiulo, G. Iodice, and F. Dammacco. 1996. Detection of hepatitis C virus (HCV) proteins by immunofluorescence and HCV RNA genomic sequences by non-isotopic in situ hybridization in bone marrow and peripheral blood mononuclear cells of chronically HCV-infected patients. Clin. Exp. Immunol. 103:414.
21. Sansonno, D., A. R. lacobelli, V. Cornacchiulo, G. Lauletta, M. A. Distasi, P. Gatti, and F. Dammacco. 1996. Immunochemical and biomolecular studies of circulating immune complexes isolated from patients with acute and chronic hepatitis C virus infection. Eur. J. Clin. Invest. 26:465.
22. Chomczynsky, P., and N. Sacchi. 1987. Single-step method of RNA isolation by guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
23. Dammacco, F., D. Sansonno, J. H. Han, V. Shyamala, V. Cornacchiulo, A. R. lacobelli, G. Lauletta, and R. Rizzi. 1994. Natural interferon-α versus its combination with 6-methyl-prednisolone in the therapy of type II mixed cryoglobulinemia: a long-term, randomized, controlled study. Blood 84:3336.
24. Stuyver, L., R. Rossau, A. Wyseur, M. Duhamel, B. Vanderborght, H. Van Heuverswyn, and G. Maertens. 1993. Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J. Gen. Virol. 74:1093.
25. Davis, G. L., J. Y. N. Lau, M. S. Urdea, P. D. Neuwald, J. C. Wilber, K. Lindsay, R. P. Perrillo, and J. Albrecht. 1994. Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optical conditions for specimen collection and clinical application in interferon-treated patients. Hepatology 19:1337.
26. Sansonno, D., V. Cornacchiulo, V. Racanelli, and F. Dammacco. 1997. In situ simultaneous detection of hepatitis C virus RNA and hepatitis C virus-related antigens in hepatocellular carcinoma. Cancer 80:22.
27. Yamada, G., H. Nishimoto, H. Endou, T. Doi, M. Takahashi, T. Tsuji H. Yoshizawa, M. Nozawa, T. Koji, and P. K. Nakane. 1993. Localization of hepatitis C virus RNA and capsid protein in human liver. Dig. Dis. Sci. 38:882.
28. Lanford, R. E., D. Chavez, F. V. Chisari, and C. Sureau. 1995. Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR. J. Virol. 69:8079.
29. Shimizu, Y. K., R. H. Purcell, and H. Yoshikura. 1993. Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro. Proc. Natl. Acad. Sci. USA 90:6037.
30. Shimizu, Y. K., S. M. Feinstone, M. Kohara, R. H. Purcell, and H. Yoshikura. 1996. Hepatitis C virus: detection of intracellular virus particles by electron microscopy. Hepatology 23:205.
31. Sansonno, D., V. Cornacchiulo, A. R. Iacobelli, P. Gatti, M. Distasi, and F. Dammacco. 1995. Demonstration and distribution of HCV RNA sequences by in situ hybridization and HCV-related proteins by immunohistochemistry in the liver tissue of patients with chronic HCV infection. Pathobiology 63:239.
32. Moldvay, J., P. Deny, S. Pol, C. Brechot, and E. Lamas. 1994. Detection of hepatitis C virus RNA in peripheral blood mononuclear cells of infected patients by in situ hybridization. Blood 83:269.
33. De Vita, S., C. Sacco, D. Sansonno, A. Gloghini, F. Dammacco, M. Crovatto, G. Santini, R. Dolcetti, M. Boiocchi, A. Carbone, and V. Zagonel. 1997. Characterization of overt B-cell lymphomas in patients with hepatitis C virus infection. Blood 90:776.
34. Knight, G. B., V. Agnello, F. Bonagura, J. L. Barnes, D. J. Panka, and Q. X. Zang. 1993. Human rheumatoid factor cross-idiotypes. IV. Studies on WA XId-positive IgM without rheumatoid factor activity provide evidence that the WA XId is not unique to rheumatoid factor and is distinct from the 17.109 and G6 XId. J. Exp. Med. 178:1903.
35. H region gene. J. Immunol. 154:413.
36. Youngblood, K., L. Fruchter, G. Ding, J. Lopez, V. Bonagura, and A. Davidson. 1994. Rheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutated. J. Clin. Invest. 93:852.
37. Lee, S. K., S. L. Bridges, P. M. Kirkham, W. J. Koopman, and H. W. Schroeder. 1994. Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis. J. Clin. Invest. 93:361.
38. Schroder, A. E., A. Greiner, C. Seyfert, and C. Berek. 1996. Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 93:221.
39. Tighe, H., K. Warnatz, D. Brinson, M. Corr, W. O. Weigle, S. M. Baird, and D. A. Carson. 1997. Peripheral deletion of rheumatoid factor B cells after abortive activation by IgG. Proc. Natl. Acad. Sci. USA 94:646.
40. Williams, R. C., C. C. Malone, and K. J. Kao. 1994. IgM rheumatoid factors react with human class I HLA molecules. J. Immunol. 156:1684.
41. Pham, B. N., F. Degos, J. F. Mosnier, S. Ollivier, A. Sauvanet, S. Erlinger, and J. H. M. Cohen. 1996. Restriction of beta gene usage of liver-derived lymphocytes in chronic hepatitis B and C. Hum. Immunol. 49:56.
42. Silvestri, F., C. Pipan, G. Barillari, F. Zaja, R. Fanin, L. Infanti, D. Russo, E. Falasca, G. Botta, and M. Baccarani. 1996. Prevalence of hepatitis C virus infection in patients with lymphoproliferative disorders. Blood 87:4296.
43. Zuckerman, E., T. Zuckerman, A. M. Levine, D. Douer, K. Gutekunst. M. Mizokami, D. G. Qian, M. Velankar, B. N. Nathwani, and T. L. Fong. 1997. Hepatitis C virus infection in patients with B-cell non-Hodgkin lymphoma. Ann. Intern. Med. 127:423.
44. Hsu, F. J., and R. Levy. 1995. Preferential use of the VH4 Ig gene family by diffuse large-cell lymphoma. Blood 86:3072.