In situ simultaneous detection of hepatitis C virus RNA and hepatitis C virus-related antigens in hepatocellular carcinoma

Cancer

Volumn 80, Issue 1, 1997, Pages 22-33

  Sansonno, Domenico ^a   Cornacchiulo, Vito ^a   Racanelli, Vito ^a   Dammacco, Franco ^a  

^a UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

Hepatitis C virus; Hepatocellular carcinoma; Immunohistochemistry; In situ hybridization

Indexed keywords

ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; DISEASE ASSOCIATION; EPIDEMIOLOGICAL DATA; HEPATITIS C; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; LIVER RESECTION; MALIGNANT TRANSFORMATION; PREDICTION; PRIORITY JOURNAL; VIRUS INFECTION; VIRUS REPLICATION;

AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; GENOTYPE; HEPACIVIRUS; HEPATITIS C ANTIGENS; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER DISEASES; LIVER NEOPLASMS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RNA, VIRAL;

EID: 0030996363     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19970701)80:1<22::AID-CNCR4>3.0.CO;2-H     Document Type: Article

References (42)

1. Morris JDH, Eddleston ALWF, Crook T. Viral infection and cancer. Lancet 1995;346:754-8.
2. Parkin DM, Stjernsward J, Muir CS. Estimates of worldwide frequency of twelve major cancers. Bull Health Organ 1994;62:163-82.
3. Ruiz J, Sangro B, Cuende JI, Beloqui O, Riezn-Boj JI, Herrero JI, et al. Hepatitis B and C viral infections in patients with hepatocellular carcinoma. Hepatology 1992;16:637-41.
4. Tsukuma H, Hiyama T, Tanaka S, Nakao M, Yabuuchi T, Kitamura T, et al. Risk factors for hepatocellular carcinoma among patients with chronic liver disease. N Engl J Med 1993;328:1797-801.
5. Liang TJ, Jeffers LJ, Reddy KR, DeMedina M, Parker IT, Cheinquer H, et al. Viral pathogenesis of hepatocellular carcinoma in the United States. Hepatology 1993;18: 1326-33.
6. Lee HS, Han CJ, Kim CY. Predominant etiologic association of hepatitis C virus with hepatocellular carcinoma compared with hepatitis B virus in elderly patients in a hepatitis B endemic area. Cancer 1993;72:2564-7.
7. Trevisani F, D'Intino PE, Caraceni P, Pizzo M, Stefanini GF, Mazziotti A, et al. Etiologic factors and clinical presentation of hepatocellular carcinoma: differences between cirrhotic and noncirrhotic Italian patients. Cancer 1995;75:2220-32.
8. Blum HE. Does hepatitis C virus cause hepatocellular carcinoma? Hepatology 1994;19:251-8.
9. Diepolder HM, Zachoval R, Hoffmann RM, Wierenga EA, Santantonio T, Jung MC, et al. Possible mechanism involving T-lymphocyte response to nonstructural protein 3 in viral clearance in acute hepatitis C virus infection. Lancet 1995; 346:1006-7.
10. Cerny A, McHutchison JG, Pasquinelli C, Brown ME, Brothers MA, Grabsceid B, et al. Hepatitis C virus specific cytotoxic T cell response: identification of multiple HLA-A2 restricted epitopes. J Clin Invest 1995;95:521-30.
11. Missale G, Bertoni R, Lamonaca V, Valli A, Massari M, Mori C, et al. Different clinical behaviours of acute hepatitis C virus infection are associated with different vigour of the anti-viral-cell-mediated immune response. J Clin Invest 1996;98:706-14.
12. Shich YSC, Skim KS, Lampertico P, Balart LA, Jeffers LJ, Thung SN, et al. Detection of hepatitis C virus sequences in liver tissue by the polymerase chain reaction. Lab Invest 1991;65:408-12.
13. Gerber MA, Shich YSC, Shim KS, Thung SN, Demetris AJ, Schwartz M, et al. Detection of replicative hepatitis C virus sequences in hepatocellular carcinoma. Am J Pathol 1992; 141:1271-7.
14. Takeda S, Shibata M, Morishima T, Harada A, Nakao A, Akimasa N, et al. Hepatitis C virus infection in hepatocellular carcinoma: detection of plus-strand and minus-strand viral RNA. Cancer 1992;70:2255-9.
15. Kobayashi S, Hayashi H, Itoh Y, Asano T, Isono K. Detection of minus-strand hepatitis C virus RNA in tumor tissues of hepatocellular carcinoma. Cancer 1994;73:48-53.
16. McGuinness PH, Bishop GA, McGaughan GW, Trowbridge R, Gowans EJ. False detection of negative-strand hepatitis C virus RNA. Lancet 1994;343:551-2.
17. Lanford RE, Chavez D, Chisari FV, Sureau C. Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR. J Virol 1995;69:8079-83.
18. Negro F, Pacchioni D, Shimizu Y, Miller RH, Bussolati G, Purcell RH, et al. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proc Natl Acad Sci USA 1992;89: 2247-51.
19. Yamada S, Koji T, Nazawa M, Kiyasawa K, Nakane PK. Detection of hepatitis C virus (HCV) RNA in paraffin-embedded tissue sections of human liver of non-A, non-B hepatitis patients by in situ hybridization. J Clin Lab Anal 1992;6:40-6.
20. Tanaka Y, Enomoto N, Kojima S, Tang L, Goto M, Marumo M, et al. Detection of hepatitis C virus RNA in the liver by in situ hybridization. Liver 1993;13:203-8.
21. Blight K, Trowbridge R, Rowland R, Gowans EJ. Detection of hepatitis C virus RNA by in situ hybridization. Liver 1992;12:286-9.
22. Sansonno D, Cornacchiulo V, Iacobelli AR, Gatti P, Distasi M, Dammacco F. Demonstration and distribution of HCV RNA sequences by in situ hybridization and HCV-related proteins by immunohistochemistry in the liver tissue of patients with chronic HCV infection. Pathobiology 1995; 63:239-48.
23. Yamada G, Nishimoto H, Endou H, Doi T, Takahashi M, Tsuji T, et al. Localization of hepatitis C virus RNA and capsid protein in human liver. Dig Dis Sci 1993;38:882-7.
24. Haruna Y, Hayashi N, Kamada T, Hytiroglou P, Thung SN, Gerber MA. Expression of hepatitis C virus in hepatocellular carcinoma. Cancer 1994;73:2253-8.
25. Sansonno D, Cornacchiulo V, Iacobelli AR, Di Stefano R, Lospalluti M, Dammacco F. Localization of hepatitis C virus antigens in liver and skin tissues of chronic hepatitis C virus- infected patients with mixed cryoglobulinemia. Hepatology 1995;21:305-12.
26. Sansonno D, Bufano G, Fiore G, Manghisi O. Correlation between hepatitis B core antigen in liver tissue and hepatitis B virus DNA in the serum of HBV infection chronic carriers. Arch Pathol Lab Med 1987;111:689-90.
27. Dammacco F, Sansonno D, Han JH, Shyamala V, Cornacchiulo V, Iacobelli AR, et al. Natural interferon α versus its combination with 6-methyl-prednisolone in the therapy of type II mixed cryoglobulinemia: a long-term, randomized, controlled study. Blood 1994;84:3336-43.
28. Okamoto H, Sugiyama S, Okata K, Kural Y, Akahane Y, Sugai Y, et al. Typing hepatitis C virus by polymerase chain reaction with type-specific primers: amplification to clinical surveys and tracing infectious sources. J Gen Virol 1992;73:673-9.
29. Stollar V, Schlesinger RW, Stevens TM. Studies on the nature of dengue virus. III. RNA synthesis in cells infected with type 2 dengue virus. Virology 1967;33:650-8.
30. Krawczynski K, Beach MJ, Bradley DW, Kuo G, Di Bisceglie AM, Houghton M, et al. Hepatitis C virus antigen in hepatocytes: immuno-morphologic detection and identification. Gastroenterology 1992;103:622-9.
31. Sansonno D, Dammacco F. Hepatitis C virus c100 antigen in liver tissue from patients with acute and chronic infection. Hepatology 1993;18:240-5.
32. Selby MJ, Choo QL, Berger K, Kuo G, Glazer E, Eckert M, et al. Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome. J Gen Virol 1993;74:1103-13.
33. Tsutsumi M, Urashima S, Takada A, Date T, Tanaka Y. Detection of antigens related to hepatitis C virus RNA encoding the NS5 region in the livers of patients with chronic type C hepatitis. Hepatology 1994;19:265-72.
34. Ballardini G, Groff P, Giostra F, Francescani R, Miniero R, Ghetti S, et al. Hepatocellular codistribution of c100, c33, c22, and NS5 hepatitis C virus antigens detected by using immunopurified polyclonal spontaneous human antibodies. Hepatology 1995;21:730-4.
35. Lo SY, Masiarz F, Hwang SR, Lai MMC, Ou JH. Differential subcellular localization of hepatitis C virus gene products. Virology 1995;213:455-61.
36. Shih CM, Lo SY, Miyamura T, Chen SY, Lee W. Suppression of hepatitis B virus expression and replication by hepatitis C virus core protein in HuH-7 cells. J Virol 1993;67:5823-32.
37. Ray RB, Lagging LM, Meyer K, Ray R. Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblast to tumorigenic phenotype. J Virol 1996; 70:4438-43.
38. Shimizu YK, Feinstone SM, Kohara M, Purcell RH, Yoshikura H. Hepatitis C virus: detection of intracellular virus particles by electron microscopy. Hepatology 1996;23:205-9.
39. Shimizu YK, Purcell RH, Yoshikura H. Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro. Proc Natl Acad Sci USA 1993;90:6037-41.
40. Sakamuro D, Furukawa T, Takegami T. Hepatitis C virus nonstructural protein NS-3 transforms NIH3T3 cells. J Virol 1995;69:3893-6.
41. Tang L, Tanaka Y, Enomoto N, Marumo F, Sato C. Detection of hepatitis C virus RNA in hepatocellular carcinoma by in situ hybridization. Cancer 1995;76:2211-6.
42. Paterlini P, Driss F, Nalpas B, Pisi E, Franco D, Berthelot P, et al. Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from HBsAg-negative patients: a study of a low-endemic area. Hepatology 1993;17:20-9.