Translational readthrough in the hdc mRNA generates a novel branching inhibitor in the Drosophila trachea

Genes and Development

Volumn 12, Issue 7, 1998, Pages 956-967

  Steneberg, Pär ^a   Englund, Camilla ^a   Kronhamn, Jesper ^a   Weaver, Thomas A ^b   Samakovlis, Christos ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b Cambridge Science Park   (United Kingdom)

Author keywords

Branching morphogenesis; Inhibition; Translational termination suppression

Indexed keywords

ANIMAL CELL; ARTICLE; LUNG DEVELOPMENT; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYSTEM; RNA TRANSLATION; TRACHEA; TRANSLATION REGULATION;

ANIMALIA; DROSOPHILA; HELIX POMATIA; HEXAPODA;

EID: 0032054838     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.12.7.956     Document Type: Article

References (37)

1. Ashburner, M., P. Thompson, J. Roote, P.F. Lasko, Y. Grau, M. El Messal, S. Roth, and P. Simpson. 1990. The genetics of a small autosomal region of Drosophila melanogaster containing the structural gene for alcohol dehydrogenase. VII. Characterization of the region around the snail and cactus loci. Genetics 126: 679-694.
2. Bergstrom, D., C. Merli, J. Cygan, R. Shelby, and R. Blackman. 1995. Regulatory autonomy and molecular characterization of the Drosophila out at first gene. Genetics 139: 1331-1346.
3. Böck, A., K. Forchhammer, J. Heider, and C. Baron. 1991. Selenoprotein synthesis: An expansion of the genetic code. Trends Biochem Sci. 16: 463-467.
4. Bodmer, R., R. Carretto, and Y. Jan. 1989. Neurogenesis of the peripheral nervous system in Drosophila embryos: DNA replication patterns and cell lineages. Neuron 3: 21-32.
5. Brand, A.H. and N. Perrimon. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
6. Campos-Ortega, A.J. and V. Hartenstein. 1985. The embryonic development of Drosophila melanogaster. Springer-Verlag, New York.
7. Cavener, D. and S. Ray. 1991. Eukaryotic start and stop translation sites. Nucleic Acids Res. 19: 3185-3192.
8. Fehon, R., I. Dawson, and S. Artavanis-Tsakonas. 1994. A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. Development 120: 545-557.
9. Feng, Y., J. Levin, D. Hatfield, T. Schaefer, R. Gorelick, and A. Rein. 1989. Suppression of UAA and UGA termination codons in mutant murine leukemia viruses. J. Virol. 63: 2870-2873.
10. Feng, Y., H. Yuan, A. Rein, and J. Levin. 1992. Bipartite signal for read-through suppression in murine leukemia virus mRNA: An eight-nucleotide purine-rich sequence immediately downstream of the gag termination codon followed by an RNA psedoknot. Virology 66: 5127-5132.
11. Folkman, J. 1995. Angiogenesis in cancer, vascular, rheumatioid and other disease. Nature Medicine 1: 27-31.
12. Fuse, N., S. Hirose, and S. Hayashi. 1994. Diploidy of Drosophila imaginal cells is maintained by a transcriptional repressor encoded by escargot. Genes & Dev. 8: 2270-2281.
13. Guillemin, K., J Groppe, K. Ducker, R. Treisman, E. Hafen, M. Affolter, and M. A. Krasnow. 1996. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122: 1353-1362.
14. Hanahan, D. and J. Folkman. 1996. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86: 353-364.
15. Hartenstein, V. and Y.N. Jan. 1992. Studying Drosophila embryogenesis with P-lacZ enhancer trap lines. Roux's Arch. Dev. Biol. 201: 194-220.
16. Hayashi, S., S. Hirose, T. Metcalfe, and A.D. Shirras. 1993. Control of imaginal cell development by the escargot gene of Drosophila. Development 118: 105-115.
17. Klämbt, C., L. Glazer, and B.-Z. Shilo. 1992. breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes & Dev. 6: 1668-1678.
18. Lee, T., N. Hacohen, M. Krasnow, and D.J. Montell. 1996. Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system. Genes & Dev. 10: 2912-2921.
19. Lehmann, R. and D. Tautz. 1994. In Situ Hybridization to RNA. Methods in cell biology: Drosophila melanogaster - Practical uses in cell and molecular biology (ed. L.S.B. Goldstein and E.A. Fyrberg), pp. 575-596. Academic Press, San Diego, CA.
20. Li, G. and C. Rice. 1989. Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: Studies of translational readthrough and its effect on virus replication. J. Virol. 63: 1326-1337.
21. Manning, G. and M.A. Krasnow. 1993. Development of the Drosophila tracheal system. The development of Drosophila melanogaster (ed. M. Bate and A.M. Arias), pp. 609-685. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
22. Perrimon, N., E. Noll, K. McCall, and A. Brand. 1991. Generating lineage-specific markers to study Drosophila development. Dev. Genet. 12: 238-252.
23. Reichman-Fried, M. and B.Z. Shilo. 1995. Breathless, a Drosophila FGF receptor homolog, is required for the onset of tracheal cell migration and tracheole formation. Mech. Dev. 52: 265-273.
24. Risau, W. 1997. Mechanisms of angiogenesis. Nature 386: 671-674.
25. Risau, W. and I. Flamme. 1995. Vasculogenesis. Annu. Rev. Cell Dev. Biol. 11: 73-91.
26. Robinson, D.N. and L. Cooley. 1997. Examination of the function of two kelch proteins generated by stop codon suppression. Development 124: 1405-1417.
27. Samakovlis, C., N. Hacohen, G. Manning, D. Sutherland, K. Guillemin, and M.A. Krasnow. 1996a. Branching morphogenesis of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events. Development 122: 1395-1407.
28. Samakovlis, C., G. Manning, P. Steneberg, N. Hacohen, R. Cantera, and M.A. Krasnow. 1996b. Genetic control of epithelial tube fusion during Drosophila tracheal development. Development 122: 3531-3536.
29. Sambrook, J., E.F. Fritsch, and T. Maniatis. 1989. Molecular cloning: A laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
30. Shiga, Y., M. Tanaka-Matakatsu, and S. Hayashi. 1996. A nuclear GFP/β-galactosidase fusion protein as a marker for morphogenesis in living Drosophila. Dev. Growth Differ. 38: 99-106.
31. Spradling, A.C. 1986. P element-mediated transformation. Drosophila - a practical approach (ed. D.B. Roberts), pp. 188-197. IRL Press Limited, Oxford, UK.
32. Spradling, A.C., D.M. Stern, I. Kiss, J. Roote, T. Laverty, and G. Rubin. 1995. Gene disruptions using P transposable elements: An integral component of the Drosophila genome project. Prof. Natl. Acad. Sci. 92: 10824-10830.
33. Sutherland, D., C. Samakovlis, and M.A. Krasnow. 1996. branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87: 1091-1101.
34. Tanaka-Matakatsu, M., T. Uemura, H. Oda, M. Takeichi, and S. Hayashi. 1996. Cadherin-mediated cell adhesion and cell motility in Drosophila trachea regulated by the transcription factor escargot. Development 122: 3697-3705.
35. Weaver, T. and R. White. 1995. headcase, an imaginal specific gene required for adult morphogenesis in Drosophila melanogaster. Development 121: 4149-4160.
36. Whiteley, M., P.D. Nogucht, S.M. Sensabaugh, W.F. Odenwald, and J.A. Kassis. 1992. The Drosophila gene escargot encodes a zinc finger motif found in snail-related genes. Mech. Dev. 36: 117-127.
37. Xue, F. and L. Cooley. 1993. kelch encodes a component of intercellular bridges in Drosophila egg chambers. Cell 72: 681-693.