Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases

Biochemical Journal

Volumn 330, Issue 2, 1998, Pages 833-838

  Mason, Robert W ^a   Sol Church, Katia ^a   Abrahamson, Magnus ^b  

^a NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; CATHEPSIN B; CATHEPSIN H; CATHEPSIN L; CATHEPSIN S; CYSTATIN C; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; LYSOSOME ENZYME; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE; PHENYLALANINE; PROTEIN INHIBITOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; ENZYME INHIBITION; ESCHERICHIA COLI; HUMAN; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA;

EID: 0032032227     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3300833     Document Type: Article

References (21)

1. Abrahamson, M., Ritonja, A., Brown, M. A., Grubb, A., Machleidt, W. and Barrett, A. J. (1987) J. Biol. Chem. 262, 9688-9694
2. Bode, W., Engh, R., Musil, D., Thiele, U., Huber, R., Karshikov, A., Brzin, J., Kos, J. and Turk, V. (1988) EMBO J. 7, 2593-2599
3. Bjork, I., Pol, E., Rayb-Segall, E., Abrahamson, M., Rowan, A. D. and Mort, J. S. (1994) Biochem. J. 299, 219-225
4. Hall, A., Hakansson, K., Mason, R. W., Grubb, A. and Abrahamson, M. (1995) J. Biol. Chem. 270, 5115-5121
5. Bromme, D., Steinert, A., Friebe, S., Fittkau, S., Wiederanders, B. and Kirschke, H. (1989) Biochem. J. 264, 475-481
6. Bromme, D., Klaus, J. L. Okamoto, K., Rasnick, D. and Palmer, J. T. (1996) Biochem. J. 315, 85-89
7. Mason, R. W. and Wilcox, D. (1993) in Advances in Cell and Molecular Biology of Membranes, vol. 1 (Storrie, B. and Murphy, R., eds.), pp. 81-116, JAI Press, New York
8. Abrahamson, M., Dalboge, H., Olafsson, I., Carlsen, S. and Grubb, A. (1988) FEBS Lett. 236, 14-18
9. Casadaban, M. J. and Cohen, S. H. (1980) J. Mol. Biol. 138, 179-207
10. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
11. Hall, A., Dalboge, H., Grubb, A. and Abrahamson, M. (1993) Biochem. J. 291, 123-129
12. Barrett, A. J., Kembhavi, A. A., Brown, M. A., Kirschke, H., Knight, G. C., Tamai, M. and Hanada, K. (1982) Biochem. J. 201, 189-198
13. Xin, X. Q., Gunesekera, B. and Mason, R. W. (1992) Arch. Biochem. Biophys. 299, 334-339
14. Mason, R. W. (1986) Biochem. J. 240, 285-288
15. Henderson, P. J. F. (1972) Biochem. J. 127, 321-333
16. Barrett, A. J. and Kirschke, H. (1981) Methods Enzymol. 80, 535-561
17. Menard, R., Carmona, E., Plouffe, C., Bromme, D., Konishi, Y., Lefebvre, J. and Storer, A. C. (1993) FEBS Lett. 328, 107-110
18. Crawford, C., Mason, R. W., Wikstrom, P. and Shaw, E. (1988) Biochem. J. 253, 751-758
19. Zumbrunn, A., Stone, S. and Shaw, E. (1988) Biochem. J. 250, 621-623
20. Mason, R. W., Green, G. D. J. and Barrett, A. J. (1985) Biochem. J. 226, 233-241
21. Dixon, M. (1953) Biochem. J. 55, 170-171