Frequent coexpression of MRP/GS-X pump and γ-glutamylcysteine synthetase mRNA in drug-resistant cells, untreated tumor cells, and normal mouse tissues

Biochemical Pharmacology

Volumn 55, Issue 5, 1998, Pages 605-615

  Kuo, M Tien ^a   Bao, Jia Ju ^a   Furuichi, Masato ^a   Yamane, Yoshiaki ^a   Gomi, Akira ^a,b   Saharaj, Niramol ^c   Masuzawa, Toshio ^b   Ishikawa, Toshihisa ^d  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b JICHI MEDICAL UNIVERSITY   (Japan)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d PFIZER INC   (United States)

Author keywords

Glutamylcysteine synthetase; Antitumor drugs; Chemotherapy; Gene regulation; Multidrug resistance protein

Indexed keywords

CISPLATIN; DOXORUBICIN; GLUTAMATE CYSTEINE LIGASE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL TISSUE; ARTICLE; COLORECTAL TUMOR; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LEUKEMIA CELL; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; DRUG RESISTANCE; DRUG RESISTANCE, NEOPLASM; GLUTAMATE-CYSTEINE LIGASE; HUMANS; MICE; MOLECULAR SEQUENCE DATA; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PEPTIDE FRAGMENTS; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0032031395     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00494-2     Document Type: Article

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