Genetic sensitivity to 6-n-propylthiouracil and sensory responses to sugar and fat mixtures

Physiology and Behavior

Volumn 63, Issue 5, 1998, Pages 771-777

  Drewnowski, Adam ^a   Ahlstrom Henderson, Susan ^a   Barratt Fornell, Anne ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

6 n Propylthiouracil (PROP); Genetic taste markers; Hedonic preference; Intensity scaling; Nontasters, medium tasters, and supertasters; Sucrose and fat

Indexed keywords

FAT; PROPYLTHIOURACIL; SUCROSE;

ADULT; ARTICLE; BODY MASS; FEMALE; GENETIC PREDISPOSITION; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL; SWEETNESS; TASTE ACUITY; TASTE DISCRIMINATION; TASTE PREFERENCE;

EID: 0032030263     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(97)00540-4     Document Type: Article

References (29)

1. Bartoshuk L. M. Bitter taste of saccharin related to the genetic ability to taste the bitter substance 6-n-propylthiouracil. Science. 205:1979;934-935.
2. Bartoshuk L. M. Separate worlds of taste. Psychol. Today. 14:1980;48-63.
3. Bartoshuk L. M. The biological basis of food perception and acceptance. Food Qual. Pref. 4:1993;21-32.
4. Bartoshuk L. M., Duffy V. B., Miller I. J. PTC/PROP tasting. Anatomy, psychophysics, and sex effects. Physiol. Behav. 56:1994;1165-1171.
5. Drewnowski A. Sweetness and obesity. Dobbing J. Sweetness. 1987;177-192 Spinger-Verlag, Berlin.
6. Drewnowski A., Brunzell J. D., Sande K., Iverius P. H., Greenwood M. R. C. Sweet tooth reconsidered Taste responsiveness in human obesity . Physiol. Behav. 35:1985;617-622.
7. Drewnowski A., Greenwood M. R. C. Cream and sugar Human preferences for high-fat foods . Physiol. Behav. 30:1983;629-633.
8. Drewnowski A., Henderson S. A., Shore A. B. Genetic sensitivity to 6-n-propylthiouracil (PROP) and hedonic responses to bitter and sweet tastes. Chem. Senses. 22:1997;27-37.
9. Drewnowski A., Henderson S. A., Shore A. B. Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. Am. J. Clin. Nutr. 66:1997;391-397.
10. Drewnowski A., Henderson S. A., Shore A. B., Barratt-Fornell A. Nontasters, tasters, and supertasters of 6-n-propylthiouracil (PROP) and hedonic response to sweet. Physiol. Behav. 62:1997;649-655.
11. Drewnowski A., Rock C. L. The influence of genetic taste markers on food acceptance. Am. J. Clin. Nutr. 62:1995;506-511.
12. Drewnowski A., Schwartz M. Invisible fats Sensory assessment of sugar/fat mixtures . Appetite. 14:1990;203-217.
13. Duffy, V. B.; Bartoshuk, L. M.; Lucchina, L. A.; Snyder, D. J.; Tym, A. Supertasters of PROP (6-n-propylthiouracil) rate the highest creaminess to high-fat milk products. AChemS XVIII Abstracts; 1997.
14. Fischer R. Genetics and gustatory chemoreception in man and other primates. Kare M., Maller O. The chemical senses and nutrition. 1967;61-81 Johns Hopkins University Press, Baltimore.
15. Fischer R. Gustatory, behavioral and pharmacological manifestations of chemoreception in man. Ohloff G., Thomas A. F. Gustation and olfaction. 1971;187-237 Academic Press, London.
16. Fischer R., Griffin F. Pharmacogenetic aspects of gustation. Drug Res. 14:1964;673-686.
17. Garner D. M., Garfinkel P. E. The Eating Attitudes Test An index of the symptoms of anorexia nervosa . Psychol. Med. 9:1979;273-279.
18. Gent J. F., Bartoshuk L. M. Sweetness of sucrose, neohesperidin dihydrochalcone, and saccharin is related to the genetic ability to taste the bitter substance 6-n-propylthiouracil. Chem. Senses. 7:1983;265-272.
19. Herman C. P. Restrained eating. Psychiatr. Clin. North Am. 1:1978;595-607.
20. Kalmus H. Improvements in the classification of the taster genotypes. Ann. Hum. Genet. 22:1958;222-230.
21. Kalmus H. Genetics of taste. Beidler L. M. Handbook of sensory physiology. 1971;165-179 Springer-Verlag, Berlin.
22. Looy H., Weingarten H. P. Facial expressions and genetic sensitivity to 6-n-propylthiouracil predict hedonic response to sweet. Physiol. Behav. 52:1992;75-82.
23. Parr L. W. Taste blindness and race. J. Hered. 25:1934;187-190.
24. Peryam D. R., Pilgrim P. J. Hedonic scale method for measuring food preferences. Food Technol. 11:1957;9-14.
25. Simon Y., Bellisle F., Monneuse M., Samuel-Lajeunesse B., Drewnowski A. Taste responsiveness in anorexia nervosa. Br. J. Psychiatry. 162:1993;244-246.
26. Tepper, B. J.; Nurse, R. J. PROP taster status is related to the perception and preference for fat. AChemS XIX Abstracts; 1997.
27. Tepper B. J., Nurse R. J. Fat perception is related to PROP taster status. Physiol. Behav. 61:1997;949-954.
28. Thompson D. A., Moskowitz H. R., Campbell R. Effects of body weight and food intake on pleasantness ratings for a sweet stimulus. J. Appl. Psychol. 41:1976;77-83.
29. Warwick Z. S., Schiffman S. S. Sensory evaluation of fat-sucrose and fat-salt mixtures Relationship to age and weight status . Physiol. Behav. 48:1990;623-636.