Indirect inhibition by antibiotics of nucleotide and deoxynucleotide biosynthesis in Plasmodium falciparum

Southeast Asian Journal of Tropical Medicine and Public Health

Volumn 29, Issue 1, 1998, Pages 24-26

  Yeo, Anthony E T ^a   Rieckmann, Karl H ^b   Christopherson, Richard I ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN ARMY MALARIA INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; AZITHROMYCIN; CHLORAMPHENICOL; CIPROFLOXACIN; DEOXYRIBONUCLEOTIDE; DOXYCYCLINE; NUCLEOTIDE;

ANIMAL; ARTICLE; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECT; PLASMODIUM FALCIPARUM;

ANIMALS; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; CHLORAMPHENICOL; CIPROFLOXACIN; DEOXYRIBONUCLEOTIDES; DOXYCYCLINE; NUCLEOTIDES; PLASMODIUM FALCIPARUM;

EID: 0032015712     PISSN: 01251562     EISSN: 26975718     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Crisp LB, Smith SM, Mathers MAG, Young GAR, Lyons SD, Christopherson RI. Effects of cytosine arabinoside on human leukemia cells. Int J Biochem Cell Biol 1996; 28 : 1061-9.
2. Gale EF, Cundliffe E, Reynolds PE, Richmond MH, Waring MJ. The molecular basis of antibiotic action. New York: Wiley, 1981.
3. Hooper DC, Wolfson JS. Mode of action of the quinolone antimicrobial agents. Rev Infect Dis 1988; 10 (Suppl 1) : S514-21.
4. Lambros C, Vanderberg JP. Synchronisation of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 1979; 65 : 418-20.
5. Miller NE, Halpert J. Analogues of chloramphenicol as mechanism based inactivators of rat liver cytochrome P-450. Modifications of the propanediol side chain, the p-nitro group, and the dichloromethyl moiety. Mol Pharmacol 1986; 29 : 391-8.
6. Prapunwattana P, O'Sullivan WJ, Yuthavong Y. Depression of Plasmodium falciparum dihydroorotate dehydrogenase activity in in vitro culture. Mol Biochem Parasitol 1988; 27 : 119-24.
7. Sant ME, Lyons SD, Phillips L, Christopherson RI. Antifolates induce inhibition of amido phosphoribosyltranferase in leukemia cells. J Biol Chem 1992; 267 : 11038-45.
8. Seymour KK, Lyons SD, Phillips L, Rieckmann KH, Christopherson RI. Cytotoxic effects of inhibitors of de novo primidine biosynthesis upon Plasmodium falciparum. Biochemistry 1994; 33 : 5268-74.
9. Sturgill MG, Rapp RP. Clarithromycin: Review of a new macrolide antibiotic with improved microbiologic spectrum and favourable pharmacokinetic and adverse effect profiles. Ann Pharamacother 1992; 26 : 1099-108.
10. Thaithong S, Beale GH. Resistance often Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests. Trans R Soc Trop Med Hyg 1981; 75 : 271-3.
11. Trager W, Jensen JB. Human malaria parasites in continuous culture. Science 1976; 193 : 673-5.
12. Yeo AET, Rieckmann KH. The in vitro antimalarial activity of chloramphenicol against Plasmodium falciparum. Acta Tropica 1994a; 56 : 51-4.
13. Yeo AET, Rieckmann KH. Prolonged exposure of Plasmodium falciparum to ciprofloxacin increase antimalarial activity. J Parasitol 1994b; 80 : 158-60.
14. Yeo AET, Rieckmann KH. Increased antimalarial activity of azithromycin during prolonged exposure of Plasmodium falciparum in vitro, Int J Parasitol 1995; 25 : 531-2.
15. Yeo AET, Seymour KK, Rieckmann KH, Christopherson RI. Effects of dual combinations of antifolates and atovaquone or dapsone on nucleotide levels in Plasmodium falciparum. Biochem Pharmacol 1997; 53: 943-50.