-
1
-
-
0016234504
-
Cyclization and N-dealkylation of chlorguanide by rabbit and rat hepatic microsomes
-
Armstrong VL and Smith CC, Cyclization and N-dealkylation of chlorguanide by rabbit and rat hepatic microsomes. Toxicol Appl Pharmacol 29: 90, 1974.
-
(1974)
Toxicol Appl Pharmacol
, vol.29
, pp. 90
-
-
Armstrong, V.L.1
Smith, C.C.2
-
2
-
-
0014442219
-
Plasmodium berghei dihydrofolate reductase. Isolation, properties and inhibition by antifolates
-
Ferone R, Burchall JJ and Hitchings GH, Plasmodium berghei dihydrofolate reductase. Isolation, properties and inhibition by antifolates. Mol Pharmacol 5: 49-59, 1969.
-
(1969)
Mol Pharmacol
, vol.5
, pp. 49-59
-
-
Ferone, R.1
Burchall, J.J.2
Hitchings, G.H.3
-
3
-
-
0014961375
-
Dihydrofolate reductase from pyrimethamine-resistant Plasmodium berghei
-
Ferone R, Dihydrofolate reductase from pyrimethamine-resistant Plasmodium berghei. J Biol Chem 245: 850-854, 1970.
-
(1970)
J Biol Chem
, vol.245
, pp. 850-854
-
-
Ferone, R.1
-
4
-
-
0015988739
-
Dihydropteroate synthase from Plasmodium berghei: Isolation, properties and inhibition by dapsone and sulfadiazine
-
McCulloch JL and Maren TH, Dihydropteroate synthase from Plasmodium berghei: Isolation, properties and inhibition by dapsone and sulfadiazine. Mol Pharmacol 10: 140-145, 1974.
-
(1974)
Mol Pharmacol
, vol.10
, pp. 140-145
-
-
McCulloch, J.L.1
Maren, T.H.2
-
5
-
-
0027180074
-
PS-15: A potent orally active antimalarial from a new class of folic acid antagonists
-
Canfield CJ, Milhous WK, Ager AL, Rossan RN, Sweeney TR, Lewis NJ and Jacobus DP, PS-15: A potent orally active antimalarial from a new class of folic acid antagonists. Am J Trop Med Hyg 49: 121-126, 1993.
-
(1993)
Am J Trop Med Hyg
, vol.49
, pp. 121-126
-
-
Canfield, C.J.1
Milhous, W.K.2
Ager, A.L.3
Rossan, R.N.4
Sweeney, T.R.5
Lewis, N.J.6
Jacobus, D.P.7
-
6
-
-
0343371216
-
The in vitro activity of experimental antimalarial compounds against strains of Plasmodium falciparum with varying degrees of sensitivity to pyrimethamine and chloroquine. Chemotherapy of malaria and resistance to antimalarials
-
Rieckmann KH, The in vitro activity of experimental antimalarial compounds against strains of Plasmodium falciparum with varying degrees of sensitivity to pyrimethamine and chloroquine. Chemotherapy of malaria and resistance to antimalarials. World Health Organ Tech Rep Ser 529: 58, 1973.
-
(1973)
World Health Organ Tech Rep Ser
, vol.529
, pp. 58
-
-
Rieckmann, K.H.1
-
7
-
-
0006498356
-
New antimalarials under development
-
Chemotherapy of Malaria (Ed. Bruce-Chwatt LK), 2nd Edn
-
Canfield CJ, New antimalarials under development. In: Chemotherapy of Malaria (Ed. Bruce-Chwatt LK), 2nd Edn, pp. 99-100. WHO Monograph Series, No. 27, 1986.
-
(1986)
WHO Monograph Series, No. 27
, vol.27
, pp. 99-100
-
-
Canfield, C.J.1
-
8
-
-
0022545467
-
Analogues of N-benzyloxy-hydrotriazines: In vitro antimalarial activity against Plasmodium falciparum
-
Childs GE and Lambros C, Analogues of N-benzyloxy-hydrotriazines: In vitro antimalarial activity against Plasmodium falciparum. Ann Trop Med Parasitol 80: 177-181, 1986.
-
(1986)
Ann Trop Med Parasitol
, vol.80
, pp. 177-181
-
-
Childs, G.E.1
Lambros, C.2
-
9
-
-
0002768313
-
Folate metabolism as a target for chemotherapy of malaria
-
Eds. Coombs GH and North MJ. Taylor & Francis, London
-
Walter RD, Folate metabolism as a target for chemotherapy of malaria. In: Biochemical Protozoology (Eds. Coombs GH and North MJ), pp. 560-568. Taylor & Francis, London, 1991.
-
(1991)
Biochemical Protozoology
, pp. 560-568
-
-
Walter, R.D.1
-
10
-
-
0029078941
-
Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro
-
Canfield CJ, Pudney M and Gutteridge WE, Interactions of atovaquone with other antimalarial drugs against Plasmodium falciparum in vitro. Exp Parasitol 80: 373-381, 1995.
-
(1995)
Exp Parasitol
, vol.80
, pp. 373-381
-
-
Canfield, C.J.1
Pudney, M.2
Gutteridge, W.E.3
-
11
-
-
0028656450
-
Multiresistant falciparum malaria cured using atovaquone and proguanil
-
Blanchard TJ, Mabey DCW, Hunt-Cooke A, Edwards G, Hutchinson DBA, Benjamin S and Chiodini PL, Multiresistant falciparum malaria cured using atovaquone and proguanil. Trans R Soc Trop Med Hyg 88: 693, 1994.
-
(1994)
Trans R Soc Trop Med Hyg
, vol.88
, pp. 693
-
-
Blanchard, T.J.1
Mabey, D.C.W.2
Hunt-Cooke, A.3
Edwards, G.4
Hutchinson, D.B.A.5
Benjamin, S.6
Chiodini, P.L.7
-
12
-
-
0026605065
-
Site of action of the antimalarial hydroxynapththoquinone, 2-[trans-4-(4′-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone (566C80)
-
Fry M and Pudney M, Site of action of the antimalarial hydroxynapththoquinone, 2-[trans-4-(4′-chlorophenyl) cyclohexyl]-3-hydroxy-1,4-naphthoquinone (566C80). Biochem Pharmacol 43: 1545-1553, 1992.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1545-1553
-
-
Fry, M.1
Pudney, M.2
-
14
-
-
0021927628
-
Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro
-
Hammond DJ, Burchell JR and Pudney M, Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitro. Mol Biochem Parasitol 14: 97-109, 1985.
-
(1985)
Mol Biochem Parasitol
, vol.14
, pp. 97-109
-
-
Hammond, D.J.1
Burchell, J.R.2
Pudney, M.3
-
15
-
-
0028242606
-
Azithromycin prophylaxis against a chloroquine resistant strains of Plasmodium falciparum
-
Kuschner RA, Heppner DG, Andersen SL, Wellde BT, Hall T, Schneider I, Ballou WR, Foulds G, Sadoff JC, Schuster B and Taylor DN, Azithromycin prophylaxis against a chloroquine resistant strains of Plasmodium falciparum. Lancet 343: 1396-1397, 1994.
-
(1994)
Lancet
, vol.343
, pp. 1396-1397
-
-
Kuschner, R.A.1
Heppner, D.G.2
Andersen, S.L.3
Wellde, B.T.4
Hall, T.5
Schneider, I.6
Ballou, W.R.7
Foulds, G.8
Sadoff, J.C.9
Schuster, B.10
Taylor, D.N.11
-
16
-
-
0025697087
-
Effects of brequinar and ciprofloxacin on de novo nucleotide biosynthesis in L1210 leukemia
-
Lyons SD and Christopherson RI, Effects of brequinar and ciprofloxacin on de novo nucleotide biosynthesis in L1210 leukemia. Biochem Int 22: 939-949, 1990.
-
(1990)
Biochem Int
, vol.22
, pp. 939-949
-
-
Lyons, S.D.1
Christopherson, R.I.2
-
17
-
-
0028013359
-
Prolonged exposure of Plasmodium falciparum to ciprofloxacin increases antimalarial activity
-
Yeo AET and Rieckmann KH, Prolonged exposure of Plasmodium falciparum to ciprofloxacin increases antimalarial activity. J Parasitol 80: 158-160, 1994.
-
(1994)
J Parasitol
, vol.80
, pp. 158-160
-
-
Yeo, A.E.T.1
Rieckmann, K.H.2
-
18
-
-
0017843255
-
A method for testing synergy with any number of agents
-
Berenbaum MC, A method for testing synergy with any number of agents. J Infect Dis 137: 122-130, 1978.
-
(1978)
J Infect Dis
, vol.137
, pp. 122-130
-
-
Berenbaum, M.C.1
-
19
-
-
0019065450
-
Correlations between methods for measurement of synergy
-
Berenbaum MC, Correlations between methods for measurement of synergy. J Infect Dis 142: 476-478, 1980.
-
(1980)
J Infect Dis
, vol.142
, pp. 476-478
-
-
Berenbaum, M.C.1
-
20
-
-
0019748202
-
Resistance often Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests
-
Thaithong S and Beale GH, Resistance often Thai isolates of Plasmodium falciparum to chloroquine and pyrimethamine by in vitro tests. Trans R Soc Trop Med Hyg 75: 271-273, 1981.
-
(1981)
Trans R Soc Trop Med Hyg
, vol.75
, pp. 271-273
-
-
Thaithong, S.1
Beale, G.H.2
-
21
-
-
0017311840
-
Human malaria parasites in continuous culture
-
Trager W and Jensen JB, Human malaria parasites in continuous culture. Science 193: 673-675, 1976.
-
(1976)
Science
, vol.193
, pp. 673-675
-
-
Trager, W.1
Jensen, J.B.2
-
22
-
-
0018704491
-
Synchronization of Plasmodium falciparum erythrocytic stages in culture
-
Lambros C and Vanderberg JP, Synchronization of Plasmodium falciparum erythrocytic stages in culture. J Parasitol 65: 418-420, 1979.
-
(1979)
J Parasitol
, vol.65
, pp. 418-420
-
-
Lambros, C.1
Vanderberg, J.P.2
-
23
-
-
0027058769
-
A bioassay for mefloquine
-
Yeo AET and Rieckmann KH, A bioassay for mefloquine. J Parasitol 78: 1096-1097, 1992.
-
(1992)
J Parasitol
, vol.78
, pp. 1096-1097
-
-
Yeo, A.E.T.1
Rieckmann, K.H.2
-
24
-
-
0028216602
-
Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum
-
Seymour KK, Lyons SD, Phillips L, Rieckmann KH and Christopherson RI, Cytotoxic effects of inhibitors of de novo pyrimidine biosynthesis upon Plasmodium falciparum. Biochemistry 33: 5268-5274, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 5268-5274
-
-
Seymour, K.K.1
Lyons, S.D.2
Phillips, L.3
Rieckmann, K.H.4
Christopherson, R.I.5
-
25
-
-
0024402491
-
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers
-
Sherman PA and Fyfe JA, Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers. Anal Biochem 180: 222-226, 1989.
-
(1989)
Anal Biochem
, vol.180
, pp. 222-226
-
-
Sherman, P.A.1
Fyfe, J.A.2
-
26
-
-
0023943586
-
Chlorproguanil/ dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: A pilot study
-
Watkins WM, Brandling-Bennett AD, Nevill CG, Carter JY, Boriga DA, Howells RE and Koech DK, Chlorproguanil/ dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: A pilot study. Trans R Soc Trop Med 82: 398-403, 1988.
-
(1988)
Trans R Soc Trop Med
, vol.82
, pp. 398-403
-
-
Watkins, W.M.1
Brandling-Bennett, A.D.2
Nevill, C.G.3
Carter, J.Y.4
Boriga, D.A.5
Howells, R.E.6
Koech, D.K.7
-
27
-
-
0028933048
-
The in vitro activity of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte colony forming units
-
Winstanley PA, Mberu EK, Szwandt ISF, Breckenridge AM and Watkins WM, The in vitro activity of novel antifolate drug combinations against Plasmodium falciparum and human granulocyte colony forming units. Antimicrob Agents Chemother 39: 948-952, 1995.
-
(1995)
Antimicrob Agents Chemother
, vol.39
, pp. 948-952
-
-
Winstanley, P.A.1
Mberu, E.K.2
Szwandt, I.S.F.3
Breckenridge, A.M.4
Watkins, W.M.5
-
28
-
-
0026099675
-
Mitochondria of mammalian Plasmodia species
-
Fry M and Beesley JE, Mitochondria of mammalian Plasmodia species. Parasitology 102: 17-26, 1991.
-
(1991)
Parasitology
, vol.102
, pp. 17-26
-
-
Fry, M.1
Beesley, J.E.2
-
29
-
-
0026765447
-
The activity in vitro of cycloguanil and pyrimethamine in combination against Plasmodium falciparum
-
Yeo AET and Rieckmann KH, The activity in vitro of cycloguanil and pyrimethamine in combination against Plasmodium falciparum. Trans R Soc Trop Med Hyg 86: 234, 1992.
-
(1992)
Trans R Soc Trop Med Hyg
, vol.86
, pp. 234
-
-
Yeo, A.E.T.1
Rieckmann, K.H.2
-
30
-
-
0023922697
-
Azithromycin, a macrolide antibiotic with potent activity against Toxoplasma gondii
-
Araujo FG, Guptill DR and Remington JS, Azithromycin, a macrolide antibiotic with potent activity against Toxoplasma gondii. Antimicrob Agents Chemother 32: 755-757, 1988.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 755-757
-
-
Araujo, F.G.1
Guptill, D.R.2
Remington, J.S.3
-
31
-
-
0026801386
-
Activity of azithromycin (CP-62,993) and erythromycin against chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum in vitro
-
Gingras BA and Jensen JB, Activity of azithromycin (CP-62,993) and erythromycin against chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum in vitro. Am J Trop Med Hyg 47: 378-382, 1992.
-
(1992)
Am J Trop Med Hyg
, vol.47
, pp. 378-382
-
-
Gingras, B.A.1
Jensen, J.B.2
-
32
-
-
0027186363
-
Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei
-
Gingras BA and Jensen JB, Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. Am J Trop Med Hyg 49: 101-105, 1993.
-
(1993)
Am J Trop Med Hyg
, vol.49
, pp. 101-105
-
-
Gingras, B.A.1
Jensen, J.B.2
-
33
-
-
0023742443
-
Mode of action of the quinolone antimicrobial agents
-
Hooper DC and Wolfson JS, Mode of action of the quinolone antimicrobial agents. Rev Infect Dis 10 (Suppl 1): S514-S521, 1988.
-
(1988)
Rev Infect Dis
, vol.10
, Issue.SUPPL. 1
-
-
Hooper, D.C.1
Wolfson, J.S.2
-
34
-
-
0023254964
-
Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth
-
Forsgren A, Bredberg A, Pardee AB, Schlossman SF and Tedder TF, Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth. Antimicrob Agents Chemother 31: 774-779, 1987.
-
(1987)
Antimicrob Agents Chemother
, vol.31
, pp. 774-779
-
-
Forsgren, A.1
Bredberg, A.2
Pardee, A.B.3
Schlossman, S.F.4
Tedder, T.F.5
|