Characterization of the microheterogeneities of PIXY321, a genetically engineered granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein expressed in yeast

European Journal of Biochemistry

Volumn 251, Issue 3, 1998, Pages 812-820

  Balland, Alain ^a   Krasts, Dace A ^a   Hoch, Kayt L ^a   Gerhart, Mary J ^a   Stremler, Kay E ^a   Waugh, Steve M ^a  

^a AMGEN INC   (United States)

Author keywords

Cytokine; Glycosylation; Heterogeneity; Recombinant protein; Saccharomyces cerevisiae

Indexed keywords

CYTOKININ; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYBRID PROTEIN; INTERLEUKIN 3; MILODISTIM; RECOMBINANT PROTEIN;

AMINO ACID COMPOSITION; ARTICLE; GENETIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN GLYCOSYLATION; PROTEIN POLYMORPHISM; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, ION EXCHANGE; CLONING, MOLECULAR; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INTERLEUKIN-3; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PEPTIDE FRAGMENTS; PEPTIDE MAPPING; PROTEIN ENGINEERING; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 0032006841     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2510812.x     Document Type: Article

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