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Volumn 3, Issue 2, 1997, Pages 113-116

The use of high-throughput synthesis and purification in the preparation of a directed library of adrenergic agents

Author keywords

Adrenergic agonists and antagonists; Ethanolamine library; Ion exchange chromatography; Parallel synthesis; Reductive amination

Indexed keywords

ADRENERGIC RECEPTOR; ADRENERGIC RECEPTOR BLOCKING AGENT; ADRENERGIC RECEPTOR STIMULATING AGENT; AMINE; ETHANOLAMINE DERIVATIVE; KETONE;

EID: 0031996291     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1009602403514     Document Type: Article
Times cited : (24)

References (17)
  • 1
    • 0015391361 scopus 로고
    • Selective beta-adrenergic receptor active drugs
    • Brittain, R.T., Selective beta-adrenergic receptor active drugs, Proc. R. Soc. Med., 65 (1972) 759-764.
    • (1972) Proc. R. Soc. Med. , vol.65 , pp. 759-764
    • Brittain, R.T.1
  • 2
    • 0000271610 scopus 로고
    • β-Adrenergic receptor
    • Hansch, C., Sammes, P.G. and Taylor, J.B. (Eds.) Pergamon, Oxford
    • Main, B.G., β-Adrenergic receptor, In Hansch, C., Sammes, P.G. and Taylor, J.B. (Eds.) Comprehensive Medicinal Chemistry, Vol. 3, Pergamon, Oxford, 1990, pp. 187-228.
    • (1990) Comprehensive Medicinal Chemistry , vol.3 , pp. 187-228
    • Main, B.G.1
  • 3
    • 0029134812 scopus 로고    scopus 로고
    • Alpha- and Beta-Adrenoceptors: From the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification
    • Hieble, J.P., Bondinell, W.E. and Ruffolo, Jr. R.R., Alpha- and Beta-Adrenoceptors: From the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification, J. Med. Chem., 38 (1996) 3415-3444.
    • (1996) J. Med. Chem. , vol.38 , pp. 3415-3444
    • Hieble, J.P.1    Bondinell, W.E.2    Ruffolo Jr., R.R.3
  • 4
    • 0028046853 scopus 로고
    • New directions in adrenoceptor pharmacology
    • a. Hieble, J.P. and Bond, R.A., New directions in adrenoceptor pharmacology, TiPS, 15 (1994) 397-399.
    • (1994) TiPS , vol.15 , pp. 397-399
    • Hieble, J.P.1    Bond, R.A.2
  • 5
    • 0030939493 scopus 로고    scopus 로고
    • Stimulation of cyclic AMP-dependent protein kinase in rat atria by (-)-GCP 12177 through atypical β-adrenoceptor
    • b. Kaumann, A.J. and Lynham, J.A., Stimulation of cyclic AMP-dependent protein kinase in rat atria by (-)-GCP 12177 through atypical β-adrenoceptor, Br. J. Pharmacol., 120 (1997) 1187-1189.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 1187-1189
    • Kaumann, A.J.1    Lynham, J.A.2
  • 6
    • 0029401349 scopus 로고
    • Structure, function, and regulation of the three beta-adrenergic receptors
    • Strosberg, A.D., Structure, function, and regulation of the three beta-adrenergic receptors, Obes. Res., 3 (1995) 501S-505S.
    • (1995) Obes. Res. , vol.3
    • Strosberg, A.D.1
  • 7
    • 0027421196 scopus 로고
    • Structure-function analysis of the three beta-adrenergic catecholamine receptors
    • Strosberg, A.D., Structure-function analysis of the three beta-adrenergic catecholamine receptors, Psychopharmacol. Ser., 10 (1993) 9-14.
    • (1993) Psychopharmacol. Ser. , vol.10 , pp. 9-14
    • Strosberg, A.D.1
  • 8
    • 0029113808 scopus 로고    scopus 로고
    • Alpha- and beta-adrenoceptors: From the gene to the clinic. 2. Structure-activity relationships and therapeutic applications
    • Ruffolo, R.R., Bondinell, W.E. and Hieble, J.P., Alpha- and beta-adrenoceptors: From the gene to the clinic. 2. Structure-activity relationships and therapeutic applications, J. Med. Chem., 38 (1996) 3681-3716.
    • (1996) J. Med. Chem. , vol.38 , pp. 3681-3716
    • Ruffolo, R.R.1    Bondinell, W.E.2    Hieble, J.P.3
  • 10
    • 0027176592 scopus 로고
    • Do β3-adrenoceptors mediate metabolic responses to isoprenaline?
    • Wheeldon, N.M., McDevitt, D.G. and Lipworth, B.J., Do β3-adrenoceptors mediate metabolic responses to isoprenaline?, Q. J. Med., 86 (1993) 595-600.
    • (1993) Q. J. Med. , vol.86 , pp. 595-600
    • Wheeldon, N.M.1    McDevitt, D.G.2    Lipworth, B.J.3
  • 11
    • 0028518565 scopus 로고
    • Coexisting beta-adrenoceptor subtypes - Significance for therogenic process in brown fat cells
    • Zhao, J., Unelius, L., Bengtsson, T., Cannon, B. and Medergaard, J., Coexisting beta-adrenoceptor subtypes - significance for therogenic process in brown fat cells, Am. J. P-Cell, 36 (1994) C969-C979.
    • (1994) Am. J. P-Cell , vol.36
    • Zhao, J.1    Unelius, L.2    Bengtsson, T.3    Cannon, B.4    Medergaard, J.5
  • 13
    • 0031021840 scopus 로고    scopus 로고
    • Ion-exchange resins for solution phase parallel synthesis of chemical libraries
    • Gayo, L.M. and Suto, M.J., Ion-exchange resins for solution phase parallel synthesis of chemical libraries, Tetrahedron Lett., 38 (1997) 513-516.
    • (1997) Tetrahedron Lett. , vol.38 , pp. 513-516
    • Gayo, L.M.1    Suto, M.J.2
  • 14
    • 0030598016 scopus 로고    scopus 로고
    • The use of union exchange resins for the synthesis of combinatorial libraries containing aryl and heteroaryl ethers
    • Parlow, J.J., The use of union exchange resins for the synthesis of combinatorial libraries containing aryl and heteroaryl ethers, Tetrahedron Lett., 37 (1996) 5257-5260.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 5257-5260
    • Parlow, J.J.1
  • 15
    • 0030973401 scopus 로고    scopus 로고
    • Automated synthesis and purification of amides. Exploitation of automated solid phase extraction in organic synthesis
    • Lawrence, R.M., Biller, S.A., Fryszman, O.M. and Poss, M.A., Automated synthesis and purification of amides. Exploitation of automated solid phase extraction in organic synthesis, Synthesis, (1997) 553-558.
    • (1997) Synthesis , pp. 553-558
    • Lawrence, R.M.1    Biller, S.A.2    Fryszman, O.M.3    Poss, M.A.4
  • 16
    • 0029926720 scopus 로고    scopus 로고
    • Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules
    • Cheng, S., Comer, D.D., Williams, J.P., Myers, P.L. and Boger, D.L., Novel solution phase strategy for the synthesis of chemical libraries containing small organic molecules, J. Am. Chem. Soc., 118 (1996) 2567-2573.
    • (1996) J. Am. Chem. Soc. , vol.118 , pp. 2567-2573
    • Cheng, S.1    Comer, D.D.2    Williams, J.P.3    Myers, P.L.4    Boger, D.L.5
  • 17
    • 0001534308 scopus 로고    scopus 로고
    • Novel solution- and solid-phase strategies for the parallel and combinatorial synthesis of small-molecular-weight compound libraries
    • Chucholowski, A., Masquelin, T., Obrecht, D., Stadlwieser, J. and Villalgordo, J.M., Novel solution- and solid-phase strategies for the parallel and combinatorial synthesis of small-molecular-weight compound libraries, Chimia, 50 (1996) 525-530.
    • (1996) Chimia , vol.50 , pp. 525-530
    • Chucholowski, A.1    Masquelin, T.2    Obrecht, D.3    Stadlwieser, J.4    Villalgordo, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.