-
1
-
-
0029922717
-
Reverse transcriptase-polymerase chain reaction amplification of MDRI gene expression in adult soft tissue sarcomas
-
Oda Y, Schneider-Stock R, Rys J, Gruchala A, Niezabitowski A, Roessner A. Reverse transcriptase-polymerase chain reaction amplification of MDRI gene expression in adult soft tissue sarcomas. Diagn Mol Pathol 1996;5:98-106.
-
(1996)
Diagn Mol Pathol
, vol.5
, pp. 98-106
-
-
Oda, Y.1
Schneider-Stock, R.2
Rys, J.3
Gruchala, A.4
Niezabitowski, A.5
Roessner, A.6
-
2
-
-
0026490804
-
Expression de la P-glycoprotéine dans le tube digestif et le foie. Implications dans la physiologie cellulaire
-
Muller C, Staumont G, Bradley G, Bibeau F, Brousset P, Laurent G. Expression de la P-glycoprotéine dans le tube digestif et le foie. Implications dans la physiologie cellulaire. Gastronterol Clin Biol 1992;16:791-7.
-
(1992)
Gastronterol Clin Biol
, vol.16
, pp. 791-797
-
-
Muller, C.1
Staumont, G.2
Bradley, G.3
Bibeau, F.4
Brousset, P.5
Laurent, G.6
-
3
-
-
0024414605
-
Structure and expression of the human MDR (P-glycoprotein) gene family
-
Chin JE, Soffir R, Noonan KE, Choik K, Roninson IB. Structure and expression of the human MDR (P-glycoprotein) gene family. Mol Cell Biol 1989;9:3808-20.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 3808-3820
-
-
Chin, J.E.1
Soffir, R.2
Noonan, K.E.3
Choik, K.4
Roninson, I.B.5
-
4
-
-
0023741129
-
Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody MRK16
-
Sugarawa I, Kataooka I, Morishita Y, Hamada H, Tsuruo T, Itoyama S, et al. Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody MRK16. Cancer Res 1988;48:4611-4.
-
(1988)
Cancer Res
, vol.48
, pp. 4611-4614
-
-
Sugarawa, I.1
Kataooka, I.2
Morishita, Y.3
Hamada, H.4
Tsuruo, T.5
Itoyama, S.6
-
5
-
-
0029073495
-
Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model
-
Joly B, Fardel O, Cecchelli R, Chesne C, Puozzo C, Guillouzo A. Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model. Toxicol in Vitro 1995;9:357-64.
-
(1995)
Toxicol in Vitro
, vol.9
, pp. 357-364
-
-
Joly, B.1
Fardel, O.2
Cecchelli, R.3
Chesne, C.4
Puozzo, C.5
Guillouzo, A.6
-
7
-
-
0029616617
-
Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms
-
Schuetz EG, Furuya N, Schuetz JD. Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms. J Pharmacol Exp Ther 1995;275:1011-8.
-
(1995)
J Pharmacol Exp Ther
, vol.275
, pp. 1011-1018
-
-
Schuetz, E.G.1
Furuya, N.2
Schuetz, J.D.3
-
8
-
-
0028069259
-
Immunohistochemical study of expression and cellular localization of the multidrug resistance gene product P-glycoprotein in primary liver carcinoma
-
Itsubo M, Ishikawa T, Toda G, Tanaka M. Immunohistochemical study of expression and cellular localization of the multidrug resistance gene product P-glycoprotein in primary liver carcinoma. Cancer 1994;73:298-303.
-
(1994)
Cancer
, vol.73
, pp. 298-303
-
-
Itsubo, M.1
Ishikawa, T.2
Toda, G.3
Tanaka, M.4
-
9
-
-
0029882948
-
Expression of P-glycoprotein in hepatocellular carcinoma: A potential marker of prognosis
-
Soini Y, Virkajärvi N, Raunio H, Pääkkö P. Expression of P-glycoprotein in hepatocellular carcinoma: a potential marker of prognosis. J Clin Pathol 1996;49:470-3.
-
(1996)
J Clin Pathol
, vol.49
, pp. 470-473
-
-
Soini, Y.1
Virkajärvi, N.2
Raunio, H.3
Pääkkö, P.4
-
10
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
Cordon-Cardo C, O'Brien JP, Boccia J, Casals D, Bertino R, Melamed MR. Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J Histochem Cytochem 1990;38:1277-87.
-
(1990)
J Histochem Cytochem
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Boccia, J.3
Casals, D.4
Bertino, R.5
Melamed, M.R.6
-
11
-
-
0029126764
-
MDRI/P-glycoprotein expression in colorectal cancer
-
Linn SC, Giaccone G. MDRI/P-glycoprotein expression in colorectal cancer. Eur J Cancer 1995;31A:1291-4.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1291-1294
-
-
Linn, S.C.1
Giaccone, G.2
-
12
-
-
0029007554
-
Expression of P-glycoprotein in the normal colorectal epithelium and in colorectal carcinoma
-
Ikeguchi M, Shirai H, Kaibara N, Ito H. Expression of P-glycoprotein in the normal colorectal epithelium and in colorectal carcinoma. Int J Oncol 1995;7:319-24.
-
(1995)
Int J Oncol
, vol.7
, pp. 319-324
-
-
Ikeguchi, M.1
Shirai, H.2
Kaibara, N.3
Ito, H.4
-
13
-
-
0024548599
-
Expression of a multidrug resistance gene in human cancer
-
Goldstein LJ, Galski H, Fojo A, Willingham M, Lai SL, Gazdar A, et al. Expression of a multidrug resistance gene in human cancer. J Natl Cancer Inst 1989;81:116-24.
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 116-124
-
-
Goldstein, L.J.1
Galski, H.2
Fojo, A.3
Willingham, M.4
Lai, S.L.5
Gazdar, A.6
-
14
-
-
0026748997
-
Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa
-
Peters WH, Boon CE, Roelofs HM, Wobbes T, Nagengast FM, Kremers PG. Expression of drug-metabolizing enzymes and P-170 glycoprotein in colorectal carcinoma and normal mucosa. Gastroenterology 1992;103:448-55.
-
(1992)
Gastroenterology
, vol.103
, pp. 448-455
-
-
Peters, W.H.1
Boon, C.E.2
Roelofs, H.M.3
Wobbes, T.4
Nagengast, F.M.5
Kremers, P.G.6
-
15
-
-
0026570652
-
The role of the MDRI (P-glycoprotein) gene in multidrug resistance in vitro and in vivo
-
Roninson IB. The role of the MDRI (P-glycoprotein) gene in multidrug resistance in vitro and in vivo. Biochem Pharmacol 1992;43:95-102.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 95-102
-
-
Roninson, I.B.1
-
16
-
-
0028920219
-
Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores
-
Sharom FJ, DiDiodato G, Yu X, Ashbourne KJD. Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores. J Biol Chem 1995;270:10334-41.
-
(1995)
J Biol Chem
, vol.270
, pp. 10334-10341
-
-
Sharom, F.J.1
DiDiodato, G.2
Yu, X.3
Ashbourne, K.J.D.4
-
17
-
-
0028639266
-
Multidrug resistance in human cancer
-
Lehnert N. Multidrug resistance in human cancer. J Neurooncol 1994;22:239-43.
-
(1994)
J Neurooncol
, vol.22
, pp. 239-243
-
-
Lehnert, N.1
-
18
-
-
0018770071
-
Altered surface membrane glycoproteins in vinca alcaloid-resistant human leukemic lymphoblasts
-
Beck WT, Mueller TJ, Tanzer LR. Altered surface membrane glycoproteins in vinca alcaloid-resistant human leukemic lymphoblasts. Cancer Res 1979;39:2070-6.
-
(1979)
Cancer Res
, vol.39
, pp. 2070-2076
-
-
Beck, W.T.1
Mueller, T.J.2
Tanzer, L.R.3
-
19
-
-
0005179167
-
Resistance to multiple chemotherapeutic agents in human cancer cells
-
Gottesman MM, Pastan I. Resistance to multiple chemotherapeutic agents in human cancer cells. Trends Pharmacol Sci 1988; 9:54-8.
-
(1988)
Trends Pharmacol Sci
, vol.9
, pp. 54-58
-
-
Gottesman, M.M.1
Pastan, I.2
-
20
-
-
0014767029
-
Cellular resistance to actinomycin D in chinese hamster cells in vitro: Cross resistance, radioautographic and cytogenetic studies
-
Biedler JL, Riemh H. Cellular resistance to actinomycin D in chinese hamster cells in vitro: cross resistance, radioautographic and cytogenetic studies. Cancer Res 1970;30:1164-74.
-
(1970)
Cancer Res
, vol.30
, pp. 1164-1174
-
-
Biedler, J.L.1
Riemh, H.2
-
21
-
-
33645830172
-
A surface glycoprotein drug permeability in chinese hamster ovary cell mutants
-
Juliano RL, Ling V. A surface glycoprotein drug permeability in chinese hamster ovary cell mutants. Biochim Biophys Acta 1976; 455:152-62.
-
(1976)
Biochim Biophys Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
22
-
-
0026327875
-
Regulation of 2-acetylaminofluorene and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450 IA gene family expression in primary hepatocytes cultures and rat liver
-
Gant TW, Silverman JA, Bisgaard HC, Burt RK, Marino PA, Thorgeirsson SS. Regulation of 2-acetylaminofluorene and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450 IA gene family expression in primary hepatocytes cultures and rat liver. Mol Carcinog 1991;4:499-509.
-
(1991)
Mol Carcinog
, vol.4
, pp. 499-509
-
-
Gant, T.W.1
Silverman, J.A.2
Bisgaard, H.C.3
Burt, R.K.4
Marino, P.A.5
Thorgeirsson, S.S.6
-
23
-
-
0023689651
-
Coinduction of MDR-I multidrug resistance and cytochrome P-450 genes in rat liver by xenobiotics
-
Burt RK, Thorgeirsson SS. Coinduction of MDR-I multidrug resistance and cytochrome P-450 genes in rat liver by xenobiotics. J Natl Cancer Inst 1988;80:1383-6.
-
(1988)
J Natl Cancer Inst
, vol.80
, pp. 1383-1386
-
-
Burt, R.K.1
Thorgeirsson, S.S.2
-
24
-
-
0027095653
-
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line
-
Cole SP, Bhardwa JG, Gerlach JH, Mackie JE, Grant CE, Almquist KC, et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science 1992; 258:1650-4.
-
(1992)
Science
, vol.258
, pp. 1650-1654
-
-
Cole, S.P.1
Bhardwa, J.G.2
Gerlach, J.H.3
Mackie, J.E.4
Grant, C.E.5
Almquist, K.C.6
-
25
-
-
0027249710
-
The MRP gene associated with a non P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein
-
Krishnamachary N, Center MS. The MRP gene associated with a non P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein. Cancer Res 1993;53:3658-61.
-
(1993)
Cancer Res
, vol.53
, pp. 3658-3661
-
-
Krishnamachary, N.1
Center, M.S.2
-
26
-
-
0028931885
-
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells
-
Brock I, Hipfner DR, Nielsen BS, Jensen PB, Deeley RG, Cole SP, et al. Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells. Cancer Res 1995;55:459-62.
-
(1995)
Cancer Res
, vol.55
, pp. 459-462
-
-
Brock, I.1
Hipfner, D.R.2
Nielsen, B.S.3
Jensen, P.B.4
Deeley, R.G.5
Cole, S.P.6
-
27
-
-
0029920244
-
Expression of the multidrug-resistance-associated protein (MRP) gene in human colorectal, gastric and non-small-cell lung carcinomas
-
Chuman Y, Sumizawa T, Takebayashi Y, Niwa K, Haraguchi M, Furukawa T, et al. Expression of the multidrug-resistance-associated protein (MRP) gene in human colorectal, gastric and non-small-cell lung carcinomas. Int J Cancer 1996;66:274-9.
-
(1996)
Int J Cancer
, vol.66
, pp. 274-279
-
-
Chuman, Y.1
Sumizawa, T.2
Takebayashi, Y.3
Niwa, K.4
Haraguchi, M.5
Furukawa, T.6
-
28
-
-
0029133131
-
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes
-
Mayer R, Kartenbeck J, Buchler M, Jedlitschky G, Leier I, Keppler D. Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J Cell Biol 1995;131:137-50.
-
(1995)
J Cell Biol
, vol.131
, pp. 137-150
-
-
Mayer, R.1
Kartenbeck, J.2
Buchler, M.3
Jedlitschky, G.4
Leier, I.5
Keppler, D.6
-
29
-
-
0029048485
-
The drug resistance-related protein LRP is the human major vault protein
-
Scheffer GL, Wijngaard PLJ, Flens MJ, Izquierdo MA, Slovak ML, Pinedo HM, et al. The drug resistance-related protein LRP is the human major vault protein. Nature 1995;1:578-82.
-
(1995)
Nature
, vol.1
, pp. 578-582
-
-
Scheffer, G.L.1
Wijngaard, P.L.J.2
Flens, M.J.3
Izquierdo, M.A.4
Slovak, M.L.5
Pinedo, H.M.6
-
30
-
-
0030590693
-
Résistance aux drogues anticancéreuscs
-
Bénard J, Rixe O. Résistance aux drogues anticancéreuscs. Presse Med 1996;25:1724-30.
-
(1996)
Presse Med
, vol.25
, pp. 1724-1730
-
-
Bénard, J.1
Rixe, O.2
-
31
-
-
0021723147
-
Studies on the polyglutamate specificity of thymidilate synthetase from fetal pig liver
-
Lu YZ, Aiello PD, Matthews RG. Studies on the polyglutamate specificity of thymidilate synthetase from fetal pig liver. Biochemistry 1984;23:6870-6.
-
(1984)
Biochemistry
, vol.23
, pp. 6870-6876
-
-
Lu, Y.Z.1
Aiello, P.D.2
Matthews, R.G.3
-
32
-
-
0343924557
-
Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal fluorouracil efficacy. Experimental data
-
Chéradame S, Etienne MC, Chazal M, Guillot T, Fischel JL, Formento P, et al. Relevance of tumoral folylpolyglutamate synthetase and reduced folates for optimal fluorouracil efficacy. Experimental data. Eur J Cancer 1997;33:950-9.
-
(1997)
Eur J Cancer
, vol.33
, pp. 950-959
-
-
Chéradame, S.1
Etienne, M.C.2
Chazal, M.3
Guillot, T.4
Fischel, J.L.5
Formento, P.6
-
33
-
-
9044250848
-
Thymidylate synthase mRNA level in adenocarcinoma of the stomach. A predictor for primary tumor response and overall survival
-
Lenz HJ, Leichman CG, Danenberg KD, Danenberg PV, Groshen S, Cohen H, et al. Thymidylate synthase mRNA level in adenocarcinoma of the stomach. A predictor for primary tumor response and overall survival. J Clin Oncol 1995;14:176-82.
-
(1995)
J Clin Oncol
, vol.14
, pp. 176-182
-
-
Lenz, H.J.1
Leichman, C.G.2
Danenberg, K.D.3
Danenberg, P.V.4
Groshen, S.5
Cohen, H.6
-
34
-
-
0024595925
-
Clinical pharmacology of 5-fluorouracil
-
Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokin 1989;16:215-37.
-
(1989)
Clin Pharmacokin
, vol.16
, pp. 215-237
-
-
Diasio, R.B.1
Harris, B.E.2
-
35
-
-
0024164649
-
Fluorouracil: Biochemistry and pharmacology
-
Pinedo HM, Peters GF. Fluorouracil: biochemistry and pharmacology. J Clin Oncol 1988;6:1653-64.
-
(1988)
J Clin Oncol
, vol.6
, pp. 1653-1664
-
-
Pinedo, H.M.1
Peters, G.F.2
-
36
-
-
0020660706
-
Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil
-
Yin MB, Zakrzewski S, Hakala MT. Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil. Mol Pharmacol 1983;23:190-7.
-
(1983)
Mol Pharmacol
, vol.23
, pp. 190-197
-
-
Yin, M.B.1
Zakrzewski, S.2
Hakala, M.T.3
-
37
-
-
0022344622
-
Thymidilate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells
-
Berger SH, Jenh CH, Johnson LF, Berger FG. Thymidilate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Mol Pharmacol 1985;28:461-7.
-
(1985)
Mol Pharmacol
, vol.28
, pp. 461-467
-
-
Berger, S.H.1
Jenh, C.H.2
Johnson, L.F.3
Berger, F.G.4
-
38
-
-
0028019880
-
Thymidilate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
-
Peters GJ, Van der Wilt CL, Van Groeningen CJ, Smid K, Meijer S, Pinedo HM. Thymidilate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil. J Clin Oncol 1994;12:2035-42.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2035-2042
-
-
Peters, G.J.1
Van Der Wilt, C.L.2
Van Groeningen, C.J.3
Smid, K.4
Meijer, S.5
Pinedo, H.M.6
-
39
-
-
0029095796
-
Quantitation of intratumoral thymidilate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers. Preliminary report from an ongoing trial
-
Leichman L, Lenz HJ, Leichman CG, Groshen S, Danenberg K, Baranda J, et al. Quantitation of intratumoral thymidilate synthase expression predicts for resistance to protracted infusion of 5-fluorouracil and weekly leucovorin in disseminated colorectal cancers. Preliminary report from an ongoing trial. Eur J Cancer 1995;31A:1306-10.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1306-1310
-
-
Leichman, L.1
Lenz, H.J.2
Leichman, C.G.3
Groshen, S.4
Danenberg, K.5
Baranda, J.6
-
40
-
-
0029918519
-
Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population
-
McMurrough J, McLeod HL. Analysis of the dihydropyrimidine dehydrogenase polymorphism in a British population. Br J Clin Pharmacol 1996;41:425-7.
-
(1996)
Br J Clin Pharmacol
, vol.41
, pp. 425-427
-
-
McMurrough, J.1
McLeod, H.L.2
-
41
-
-
0022448330
-
Distribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrate
-
Ho DH, Townsend L, Luna MA, Bodey GP. Distribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrate. Anticancer Res 1986;6: 781-4.
-
(1986)
Anticancer Res
, vol.6
, pp. 781-784
-
-
Ho, D.H.1
Townsend, L.2
Luna, M.A.3
Bodey, G.P.4
-
42
-
-
0027993135
-
Wide range for optimal concentration of folinic acid in fluorouracil modulation. Experimental data on human tumor cell lines
-
Beck A, Etienne MC, Chéradame S, Fischel JL, Formento P, Guillot T. Wide range for optimal concentration of folinic acid in fluorouracil modulation. Experimental data on human tumor cell lines. Eur J Cancer 1994;30A:1522-6.
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 1522-1526
-
-
Beck, A.1
Etienne, M.C.2
Chéradame, S.3
Fischel, J.L.4
Formento, P.5
Guillot, T.6
-
43
-
-
0028982820
-
Response to fluorouracil therapy in cancer patients: The role of tumoral dihydropyrimidine dehydrogenase activity
-
Etienne MC, Chéradame S, Fischel JL, Formento P, Dassonville O, Renée N. Response to fluorouracil therapy in cancer patients: the role of tumoral dihydropyrimidine dehydrogenase activity. J Clin Oncol 1995;13:1663-70.
-
(1995)
J Clin Oncol
, vol.13
, pp. 1663-1670
-
-
Etienne, M.C.1
Chéradame, S.2
Fischel, J.L.3
Formento, P.4
Dassonville, O.5
Renée, N.6
-
44
-
-
0027534425
-
Dihydropyrimidine dehydrogenase activity in cancer patients
-
Fleming RA, Milano GA, Gaspard MH, Bargnoux PJ, Thyss A, Plagne R, et al. Dihydropyrimidine dehydrogenase activity in cancer patients. Eur J Cancer 1993;29A:740-4.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 740-744
-
-
Fleming, R.A.1
Milano, G.A.2
Gaspard, M.H.3
Bargnoux, P.J.4
Thyss, A.5
Plagne, R.6
-
45
-
-
0030892459
-
Optimiser la chimiothérapie dans les cancers digestifs. L'exemple des cancers colorectaux métastasés
-
Rougier P, Ducreux M. Optimiser la chimiothérapie dans les cancers digestifs. L'exemple des cancers colorectaux métastasés. Hépato-Gastro 1997;4:91-101.
-
(1997)
Hépato-Gastro
, vol.4
, pp. 91-101
-
-
Rougier, P.1
Ducreux, M.2
-
46
-
-
0022398782
-
Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil and thymine by rat liver dihydropyrimidine dehydrogenase
-
Tuchman M, Ramnaraine ML, O'Dea RF. Effects of uridine and thymidine on the degradation of 5-fluorouracil, uracil and thymine by rat liver dihydropyrimidine dehydrogenase. Cancer Res 1985; 45:5553-6.
-
(1985)
Cancer Res
, vol.45
, pp. 5553-5556
-
-
Tuchman, M.1
Ramnaraine, M.L.2
O'Dea, R.F.3
-
47
-
-
0027496582
-
Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency
-
Houyau P, Gay C, Chatelut E, Canal P, Roche H, Milano G. Severe fluorouracil toxicity in a patient with dihydropyrimidine dehydrogenase deficiency. J Natl Cancer Inst 1993;85:1602-3.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1602-1603
-
-
Houyau, P.1
Gay, C.2
Chatelut, E.3
Canal, P.4
Roche, H.5
Milano, G.6
-
48
-
-
0003215939
-
Soluble glutathione transferase isoenzymes
-
Sies H, Ketterer B, eds. London: Academic Press
-
Ketterer B, Meyer DJ, Klark A. Soluble glutathione transferase isoenzymes. In: Glutathione conjugation. Mechanisms and biological significance. Sies H, Ketterer B, eds. London: Academic Press, 1988: 73-125.
-
(1988)
Glutathione Conjugation. Mechanisms and Biological Significance
, pp. 73-125
-
-
Ketterer, B.1
Meyer, D.J.2
Klark, A.3
-
49
-
-
0021853192
-
Glutathione transferase in primary rat hepatomas. The isolation of a form with GSH peroxidase activity
-
Meyer DJ, Beale D, Tan KH, Coles B, Ketterer B. Glutathione transferase in primary rat hepatomas. The isolation of a form with GSH peroxidase activity. FEBS Lett 1985;184:139-43.
-
(1985)
FEBS Lett
, vol.184
, pp. 139-143
-
-
Meyer, D.J.1
Beale, D.2
Tan, K.H.3
Coles, B.4
Ketterer, B.5
-
50
-
-
0023037085
-
Overexpression of a novel anionic resistant glutathione transferase in multidrug-resistant human breast cancer cells
-
Batist G, Tulpule A, Sinha BK, Katki AG, Myers CE, Cowan KH. Overexpression of a novel anionic resistant glutathione transferase in multidrug-resistant human breast cancer cells. J Biol Chem 1986;261:15544-9.
-
(1986)
J Biol Chem
, vol.261
, pp. 15544-15549
-
-
Batist, G.1
Tulpule, A.2
Sinha, B.K.3
Katki, A.G.4
Myers, C.E.5
Cowan, K.H.6
-
51
-
-
0024322933
-
Glutathione and glutathione-S-transferase in a human plasma cell line resistant to mephalan
-
Gupta V, Singh SV, Ahmad H, Medh RD, Awasthi YC. Glutathione and glutathione-S-transferase in a human plasma cell line resistant to mephalan. Biochem Pharmacol 1989;38:1993-2000.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 1993-2000
-
-
Gupta, V.1
Singh, S.V.2
Ahmad, H.3
Medh, R.D.4
Awasthi, Y.C.5
-
52
-
-
0030064573
-
Insights into mechanisms of cisplatine resistance and potential for its clinical reversal
-
Gosland M, Lum B, Schimmelpfennig J, Baker J, Doukas M. Insights into mechanisms of cisplatine resistance and potential for its clinical reversal. Pharmacotherapy 1996;16:16-39.
-
(1996)
Pharmacotherapy
, vol.16
, pp. 16-39
-
-
Gosland, M.1
Lum, B.2
Schimmelpfennig, J.3
Baker, J.4
Doukas, M.5
-
53
-
-
0028099203
-
Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis
-
Satoh M, Cherian MG, Imura N, Shimizu H. Modulation of resistance to anticancer drugs by inhibition of metallothionein synthesis. Cancer Res 1994;54:5255-7.
-
(1994)
Cancer Res
, vol.54
, pp. 5255-5257
-
-
Satoh, M.1
Cherian, M.G.2
Imura, N.3
Shimizu, H.4
-
54
-
-
0002048709
-
Adaptative response: Induced synthesis of DNA repair enzymes by alkylating agents
-
Sekigushi M, Nakabeppu Y. Adaptative response: induced synthesis of DNA repair enzymes by alkylating agents. Trends Genet 1987;3:51-4.
-
(1987)
Trends Genet
, vol.3
, pp. 51-54
-
-
Sekigushi, M.1
Nakabeppu, Y.2
-
56
-
-
0025890181
-
6-methylguanine-DNA methyltransferase in transgenic mice introduced with the E.coli ada gene
-
6-methylguanine-DNA methyltransferase in transgenic mice introduced with the E.coli ada gene. Mutat Res 1991; 254:225-30.
-
(1991)
Mutat Res
, vol.254
, pp. 225-230
-
-
Nakatsuru, Y.1
Matsukuma, S.2
Sekiguchi, M.3
Ishikawa, T.4
-
59
-
-
0028983196
-
6-methylguanine-DNA methyltransferase-expression in human tumors by means of in situ hybridization
-
6-methylguanine-DNA methyltransferase-expression in human tumors by means of in situ hybridization. Anticancer Res 1995;15: 761-7.
-
(1995)
Anticancer Res
, vol.15
, pp. 761-767
-
-
Eberhagen, I.1
Bankmann, M.2
Kaina, B.3
-
60
-
-
0028985931
-
6-alkylguanine-DNA alkyltransferase gene in normal breast and skin tissue: In situ mapping of cell type-specific expression
-
6-alkylguanine-DNA alkyltransferase gene in normal breast and skin tissue: in situ mapping of cell type-specific expression. Mol Carcinog 1995;12:177-84.
-
(1995)
Mol Carcinog
, vol.12
, pp. 177-184
-
-
Wani, G.1
D'Ambrosio, S.M.2
-
61
-
-
0029094616
-
Role of apoptosis in biology and pathology. Resistance to apoptosis in colon carcinogenesis
-
Payne CM, Bernstein H, Bernstein C, Garewal H. Role of apoptosis in biology and pathology. Resistance to apoptosis in colon carcinogenesis. Ultrastruct Pathol 1995;19:221-48.
-
(1995)
Ultrastruct Pathol
, vol.19
, pp. 221-248
-
-
Payne, C.M.1
Bernstein, H.2
Bernstein, C.3
Garewal, H.4
-
62
-
-
0028276714
-
Resistance of aberrant crypt foci to apoptosis induced by azoxymethane in rats chronically fed cholic acid
-
Magnuson BA, Shirtliff N, Bird RP. Resistance of aberrant crypt foci to apoptosis induced by azoxymethane in rats chronically fed cholic acid. Carcinogenesis 1994;15:1459-62.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1459-1462
-
-
Magnuson, B.A.1
Shirtliff, N.2
Bird, R.P.3
-
64
-
-
0028910555
-
The mutational status of P53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents
-
Nabeya Y, Loganzo F, Maslak P, Lai L, De Oliveira AR, Schwartz GK, et al. The mutational status of P53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents. Int J Cancer 1995;64:37-46.
-
(1995)
Int J Cancer
, vol.64
, pp. 37-46
-
-
Nabeya, Y.1
Loganzo, F.2
Maslak, P.3
Lai, L.4
De Oliveira, A.R.5
Schwartz, G.K.6
-
65
-
-
0027282044
-
Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, Turka LA, et al. Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993;74:597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
-
66
-
-
0030049639
-
Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression
-
Walker TL, White JD, Esdale WJ, Burton MA, DeCruz EE. Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression. Br J Cancer 1996;73: 610-4.
-
(1996)
Br J Cancer
, vol.73
, pp. 610-614
-
-
Walker, T.L.1
White, J.D.2
Esdale, W.J.3
Burton, M.A.4
DeCruz, E.E.5
-
67
-
-
0015292126
-
Treatment of malignant melanoma with camptothecin (NSC-100880)
-
Gottlieb JA, Luce JK. Treatment of malignant melanoma with camptothecin (NSC-100880). Cancer Chemother Rep 1972;56: 103-5.
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 103-105
-
-
Gottlieb, J.A.1
Luce, J.K.2
-
68
-
-
0029612305
-
Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung
-
Giaccone G, Vanarkotte J, Scagliotti G, Capranico G, Vandervalk P, Rubio G, et al. Differential expression of DNA topoisomerases in non-small cell lung cancer and normal lung. Biochim Biophys Acta 1995;1264:337-46.
-
(1995)
Biochim Biophys Acta
, vol.1264
, pp. 337-346
-
-
Giaccone, G.1
Vanarkotte, J.2
Scagliotti, G.3
Capranico, G.4
Vandervalk, P.5
Rubio, G.6
-
69
-
-
0027972726
-
New drugs. Topoisomerase I inhibitors: Topotecan and irinotecan
-
Creemerst GJ, Lund B, Verweij T. New drugs. Topoisomerase I inhibitors: topotecan and irinotecan. Cancer Treat Rev 1994;20: 73-96.
-
(1994)
Cancer Treat Rev
, vol.20
, pp. 73-96
-
-
Creemerst, G.J.1
Lund, B.2
Verweij, T.3
-
71
-
-
0028440146
-
Résistance cellulaire aux inhibiteurs de la topo-isomérase II
-
Paris
-
Jacquemin-Sablon A, Bojanowski K, Casabianca-Pignède MR, Crémier S, Delaporte C, Khelifa T, et al. Résistance cellulaire aux inhibiteurs de la topo-isomérase II Bull Cancer (Paris) 1994;81: 381-5.
-
(1994)
Bull Cancer
, vol.81
, pp. 381-385
-
-
Jacquemin-Sablon, A.1
Bojanowski, K.2
Casabianca-Pignède, M.R.3
Crémier, S.4
Delaporte, C.5
Khelifa, T.6
-
72
-
-
0030939222
-
Résistance aux médicaments anticancéreux: Approches théoriques et expérimentales
-
Chauffert B. Résistance aux médicaments anticancéreux: approches théoriques et expérimentales. Hépato-Gastro 1997;4:102-9.
-
(1997)
Hépato-Gastro
, vol.4
, pp. 102-109
-
-
Chauffert, B.1
-
73
-
-
78651053628
-
Primary carcinoma of the liver: A study of 100 cases among 48900 necropsies
-
Edmonson HA, Steiner PE. Primary carcinoma of the liver: a study of 100 cases among 48900 necropsies. Cancer 1954;7:462-503.
-
(1954)
Cancer
, vol.7
, pp. 462-503
-
-
Edmonson, H.A.1
Steiner, P.E.2
-
74
-
-
0026555717
-
Modulation of activity of the promoter of the human MDRI gene by Ras and p53
-
Chin KW, Ueda K, Pastan I, Gottesman MM. Modulation of activity of the promoter of the human MDRI gene by Ras and p53. Science 1992;255:459-62.
-
(1992)
Science
, vol.255
, pp. 459-462
-
-
Chin, K.W.1
Ueda, K.2
Pastan, I.3
Gottesman, M.M.4
-
75
-
-
0030271893
-
Immunohistochemical study of expression of P-glycoprotein and mutant p53 protein in hepatocellular carcinoma from the viewpoint of modulation of transcriptional activity of MDRI gene
-
Itsubo M, Toda G. Immunohistochemical study of expression of P-glycoprotein and mutant p53 protein in hepatocellular carcinoma from the viewpoint of modulation of transcriptional activity of MDRI gene. Int Hepatol Commun 1996;5:317-25.
-
(1996)
Int Hepatol Commun
, vol.5
, pp. 317-325
-
-
Itsubo, M.1
Toda, G.2
-
76
-
-
0027379619
-
The chemotherapy of colon cancer can no longer be ignored
-
Cunningham D, Findlay M. The chemotherapy of colon cancer can no longer be ignored. Eur J Cancer 1993;29A:2077-9.
-
(1993)
Eur J Cancer
, vol.29 A
, pp. 2077-2079
-
-
Cunningham, D.1
Findlay, M.2
-
77
-
-
0001554828
-
The classification of cancer of the rectum
-
Dukes CE. The classification of cancer of the rectum. J Pathol 1932;35:323-32.
-
(1932)
J Pathol
, vol.35
, pp. 323-332
-
-
Dukes, C.E.1
-
78
-
-
0023195285
-
Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells
-
Goodman GE, Yen YP, Cox TC, Crowley J. Effect of verapamil on in vitro cytotoxicity of adriamycin and vinblastine in human tumor cells. Cancer Res 1987;47:2295-304.
-
(1987)
Cancer Res
, vol.47
, pp. 2295-2304
-
-
Goodman, G.E.1
Yen, Y.P.2
Cox, T.C.3
Crowley, J.4
-
79
-
-
0026773350
-
Various methods of analysis of mdrI/P-glycoprotein in human colon cancer cell lines
-
Herzog CE, Trepel JB, Mickey LA, Bates SE, Fojo AT. Various methods of analysis of mdrI/P-glycoprotein in human colon cancer cell lines. J Natl Cancer Inst 1992;84:711-6.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 711-716
-
-
Herzog, C.E.1
Trepel, J.B.2
Mickey, L.A.3
Bates, S.E.4
Fojo, A.T.5
-
80
-
-
0028151449
-
The role of thymidilate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
-
Johnston PG, Fisher E, Rockette HE, Fisher B, Wolmark N, Drake JC, et al. The role of thymidilate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994;12:2640-7.
-
(1994)
J Clin Oncol
, vol.12
, pp. 2640-2647
-
-
Johnston, P.G.1
Fisher, E.2
Rockette, H.E.3
Fisher, B.4
Wolmark, N.5
Drake, J.C.6
-
81
-
-
0024358188
-
DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts
-
Giovanella BC, Stehlin JS, Wall ME, Wani MC, Nicholas AW, Liu LF, et al. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts. Science 1989;246:1046-8.
-
(1989)
Science
, vol.246
, pp. 1046-1048
-
-
Giovanella, B.C.1
Stehlin, J.S.2
Wall, M.E.3
Wani, M.C.4
Nicholas, A.W.5
Liu, L.F.6
-
82
-
-
0029738119
-
P53 nuclear protein overexpression in colorectal cancer. A dominant predictor of survival in patients with advanced hepatic metastases
-
Belluco C, Guillem JG, Kemeny N, Huang Y, Klimstra D, Berger MF, et al. P53 nuclear protein overexpression in colorectal cancer. A dominant predictor of survival in patients with advanced hepatic metastases. J Clin Oncol 1996;14:2696-701.
-
(1996)
J Clin Oncol
, vol.14
, pp. 2696-2701
-
-
Belluco, C.1
Guillem, J.G.2
Kemeny, N.3
Huang, Y.4
Klimstra, D.5
Berger, M.F.6
-
83
-
-
0028940399
-
Thymidilate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors
-
Johnston PG, Lenz HJ, Leichman CG, Danenberg KD, Leichman L. Thymidilate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors. Cancer Res 1995;55:1407-12.
-
(1995)
Cancer Res
, vol.55
, pp. 1407-1412
-
-
Johnston, P.G.1
Lenz, H.J.2
Leichman, C.G.3
Danenberg, K.D.4
Leichman, L.5
-
84
-
-
0029922396
-
Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells
-
Inaba M, Junko M, Hiroko S, Miike N, Naoe Y, Daimon A, et al. Reduced activity of anabolizing enzymes in 5-fluorouracil-resistant human stomach cancer cells. Jpn J Cancer Res 1996;87: 212-20.
-
(1996)
Jpn J Cancer Res
, vol.87
, pp. 212-220
-
-
Inaba, M.1
Junko, M.2
Hiroko, S.3
Miike, N.4
Naoe, Y.5
Daimon, A.6
-
85
-
-
0020426820
-
Increased accumulation of vincristine and adriamycin in drug resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors
-
Tsuruo T, Lida H, Teukagothl S, Sakurai V. Increased accumulation of vincristine and adriamycin in drug resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors. Cancer Res 1982;42:4730-3.
-
(1982)
Cancer Res
, vol.42
, pp. 4730-4733
-
-
Tsuruo, T.1
Lida, H.2
Teukagothl, S.3
Sakurai, V.4
-
86
-
-
0021180629
-
Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells
-
Tsuruo T, Iida H, Kititani Y, Yokata K, Tsukagoshi S, Sakurai Y. Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells. Cancer Res 1984;44:4303-7.
-
(1984)
Cancer Res
, vol.44
, pp. 4303-4307
-
-
Tsuruo, T.1
Iida, H.2
Kititani, Y.3
Yokata, K.4
Tsukagoshi, S.5
Sakurai, Y.6
-
87
-
-
0027332882
-
Phase I/pharmacokinetic study of high-dose progesterone and doxorubicine
-
Christen RD, McClay EF, Plaxe SC, Yen SS, Kim S, Kirmani S, et al. Phase I/pharmacokinetic study of high-dose progesterone and doxorubicine. J Clin Oncol 1993;11:2417-26.
-
(1993)
J Clin Oncol
, vol.11
, pp. 2417-2426
-
-
Christen, R.D.1
McClay, E.F.2
Plaxe, S.C.3
Yen, S.S.4
Kim, S.5
Kirmani, S.6
-
88
-
-
0021162802
-
Reversal of acquired resistance to doxorubicin in P388 murine cells by tamoxifen and other triparanol analogues
-
Ramu A, Glaubiger D, Fuks Z. Reversal of acquired resistance to doxorubicin in P388 murine cells by tamoxifen and other triparanol analogues. Cancer Res 1984;44:4392-5.
-
(1984)
Cancer Res
, vol.44
, pp. 4392-4395
-
-
Ramu, A.1
Glaubiger, D.2
Fuks, Z.3
-
89
-
-
0026584396
-
Cyclosporine as drug resistance modiflore
-
Twentyman PR. Cyclosporine as drug resistance modiflore. Biochem Pharmacol 1992;43:109-17.
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 109-117
-
-
Twentyman, P.R.1
-
90
-
-
0026634681
-
Modulation of multidrug-resistant multiple myeloma by cyclosporin
-
Sonneveld P, Durie BGM, Lokhorst HM, Maric T, Soebu G, Sucin S, et al. Modulation of multidrug-resistant multiple myeloma by cyclosporin. Lancet 1992;340:255-9.
-
(1992)
Lancet
, vol.340
, pp. 255-259
-
-
Sonneveld, P.1
Durie, B.G.M.2
Lokhorst, H.M.3
Maric, T.4
Soebu, G.5
Sucin, S.6
-
91
-
-
0029047741
-
Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells
-
Fardel O, Lecureur V, Loyer P, Guillouzo A. Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells. Biochem Pharmacol 1995;49:1255-60.
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1255-1260
-
-
Fardel, O.1
Lecureur, V.2
Loyer, P.3
Guillouzo, A.4
-
92
-
-
0026711242
-
Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody
-
Mechetner EB, Roninson IB. Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. Proc Natl Acad Sci USA 1992;89:5824-8.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5824-5828
-
-
Mechetner, E.B.1
Roninson, I.B.2
-
93
-
-
0028887855
-
Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicine in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells
-
Merlin JL, Marchal S, Ramacci C, Dieterlen A, Schultz G, Lucas C, et al. Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicine in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells. Cytometry 1995;20:315-23.
-
(1995)
Cytometry
, vol.20
, pp. 315-323
-
-
Merlin, J.L.1
Marchal, S.2
Ramacci, C.3
Dieterlen, A.4
Schultz, G.5
Lucas, C.6
-
94
-
-
0029074062
-
Circumvention of P-glycoprotein-mediated drug resistance in human leukaemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833
-
Jiang XR, Kelsey SM, Wu YL, Newland AC. Circumvention of P-glycoprotein-mediated drug resistance in human leukaemic cells by non-immunosuppressive cyclosporin D analogue, SDZ PSC 833. Br J Haematol 1995;90:375-83.
-
(1995)
Br J Haematol
, vol.90
, pp. 375-383
-
-
Jiang, X.R.1
Kelsey, S.M.2
Wu, Y.L.3
Newland, A.C.4
-
95
-
-
0029809499
-
Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979
-
Dantzig AH, Shepard RL, Cao J, Law KL, Ehlhardt WJ, Baughman TM, et al. Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979. Cancer Res 1996;56:4171-9.
-
(1996)
Cancer Res
, vol.56
, pp. 4171-4179
-
-
Dantzig, A.H.1
Shepard, R.L.2
Cao, J.3
Law, K.L.4
Ehlhardt, W.J.5
Baughman, T.M.6
-
96
-
-
0026498012
-
Modulation of multidrug gene expression in rat hepatocytes maintained under various culture conditions
-
Fardel O, Loyer P, Morel F, Ratanasavanh D, Guillouzo A. Modulation of multidrug gene expression in rat hepatocytes maintained under various culture conditions. Biochem Pharmacol 1992;44:2259-62.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 2259-2262
-
-
Fardel, O.1
Loyer, P.2
Morel, F.3
Ratanasavanh, D.4
Guillouzo, A.5
-
97
-
-
0027296765
-
Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes
-
Fardel O, Lécureur V, Guillouzo A. Regulation by dexamethasone of P-glycoprotein expression in cultured rat hepatocytes. FEBS Lett 1993;327:189-93.
-
(1993)
FEBS Lett
, vol.327
, pp. 189-193
-
-
Fardel, O.1
Lécureur, V.2
Guillouzo, A.3
-
98
-
-
7144249006
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
Ford IM, Hait WN. Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol Rev 1990;171:1002-7.
-
(1990)
Pharmacol Rev
, vol.171
, pp. 1002-1007
-
-
Ford, I.M.1
Hait, W.N.2
-
99
-
-
0026051296
-
P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high dose verapamil
-
Miller TP, Grogan TM, Dalton E, Spier CM, Scheper RJ, Salmon SE. P-glycoprotein expression in malignant lymphoma and reversal of clinical drug resistance with chemotherapy plus high dose verapamil. J Clin Oncol 1991;9:17-24.
-
(1991)
J Clin Oncol
, vol.9
, pp. 17-24
-
-
Miller, T.P.1
Grogan, T.M.2
Dalton, E.3
Spier, C.M.4
Scheper, R.J.5
Salmon, S.E.6
-
100
-
-
0028028123
-
The antiprogestatin drug RU486 potentiates doxorubicin cytotoxicity in multidrug resistant cells through inhibition of P-glycoprotein function
-
Lécureur V, Fardel O, Guillouzo A. The antiprogestatin drug RU486 potentiates doxorubicin cytotoxicity in multidrug resistant cells through inhibition of P-glycoprotein function. FEBS Lett 1994;355:187-91.
-
(1994)
FEBS Lett
, vol.355
, pp. 187-191
-
-
Lécureur, V.1
Fardel, O.2
Guillouzo, A.3
-
101
-
-
0029685763
-
Modulation of multidrug resistance with antisense oligodeoxynucleotide to MDRI mRNA
-
Sola JE, Colombani PM. Modulation of multidrug resistance with antisense oligodeoxynucleotide to MDRI mRNA. Ann Surg Oncol 1996;3:80-5.
-
(1996)
Ann Surg Oncol
, vol.3
, pp. 80-85
-
-
Sola, J.E.1
Colombani, P.M.2
-
102
-
-
0026770694
-
Increased accumulation of drugs in multidrug-resistant cells induced by liposomes
-
Warren L, Jardiller JC, Malarska A, Akelli MG. Increased accumulation of drugs in multidrug-resistant cells induced by liposomes. Cancer Res 1992;52:3241-5.
-
(1992)
Cancer Res
, vol.52
, pp. 3241-3245
-
-
Warren, L.1
Jardiller, J.C.2
Malarska, A.3
Akelli, M.G.4
-
103
-
-
0029875854
-
On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance
-
Hu YP, Jarillon S, Dubernet C, Couvreur P, Robert J. On the mechanism of action of doxorubicin encapsulation in nanospheres for the reversal of multidrug resistance. Cancer Chemother Pharmacol 1996;37:556-60.
-
(1996)
Cancer Chemother Pharmacol
, vol.37
, pp. 556-560
-
-
Hu, Y.P.1
Jarillon, S.2
Dubernet, C.3
Couvreur, P.4
Robert, J.5
-
104
-
-
0030590689
-
Chimiothérapie des cancers colorectaux avec métastases
-
De Gramont A, Louvet C, André T, Tournigand C, Raymond E, Krulik M. Chimiothérapie des cancers colorectaux avec métastases. Presse Med 1996;25:1678-82.
-
(1996)
Presse Med
, vol.25
, pp. 1678-1682
-
-
De Gramont, A.1
Louvet, C.2
André, T.3
Tournigand, C.4
Raymond, E.5
Krulik, M.6
-
105
-
-
0024539308
-
A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: A mid-atlantic oncology program study
-
Lokich JJ, Ahlgren JD, Gullo JJ, Philips JA, Fryer JG. A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a mid-atlantic oncology program study. J Clin Oncol 1989;7:425-32.
-
(1989)
J Clin Oncol
, vol.7
, pp. 425-432
-
-
Lokich, J.J.1
Ahlgren, J.D.2
Gullo, J.J.3
Philips, J.A.4
Fryer, J.G.5
-
106
-
-
0025774575
-
Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Possible relevance to regional chemotherapy
-
Daher GC, Naguib FNM, El Kouni MH, Zhang R, Soong SJ, Diasio RB. Inhibition of fluoropyrimidine catabolism by benzyloxybenzyluracil. Possible relevance to regional chemotherapy. Biochem Pharmacol 1991;41:1887-93.
-
(1991)
Biochem Pharmacol
, vol.41
, pp. 1887-1893
-
-
Daher, G.C.1
Naguib, F.N.M.2
El Kouni, M.H.3
Zhang, R.4
Soong, S.J.5
Diasio, R.B.6
-
107
-
-
0026701936
-
Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil
-
Porter D, Chestnut W, Merrill B, Spector T. Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil. J Biol Chem 1992;267:5236-42.
-
(1992)
J Biol Chem
, vol.267
, pp. 5236-5242
-
-
Porter, D.1
Chestnut, W.2
Merrill, B.3
Spector, T.4
-
108
-
-
0029068999
-
Intratumoral dihydropyrimidine dehydrogenase and its inhibition: A new approach in the pharmacokinetics of 5-fluorouracil
-
Milano G, Etienne MC, Fischel JL. Intratumoral dihydropyrimidine dehydrogenase and its inhibition: a new approach in the pharmacokinetics of 5-fluorouracil. Ann Gastroenterol Hepatol 1995;31:103-5.
-
(1995)
Ann Gastroenterol Hepatol
, vol.31
, pp. 103-105
-
-
Milano, G.1
Etienne, M.C.2
Fischel, J.L.3
-
109
-
-
0027135995
-
5-ethynyluracil (776C85): Inactivation of dihydropyrimidine dehydrogenase in vivo
-
Spector T, Harrington J, Porter DJ. 5-ethynyluracil (776C85): inactivation of dihydropyrimidine dehydrogenase in vivo. Biochem Pharmacol 1993;46:2243-8.
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 2243-2248
-
-
Spector, T.1
Harrington, J.2
Porter, D.J.3
-
110
-
-
0028281781
-
5-ethynyluracil (776C85): Modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma
-
Cao S, Rustum YM, Spector T. 5-ethynyluracil (776C85): modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma. Cancer Res 1994;54: 1507-10.
-
(1994)
Cancer Res
, vol.54
, pp. 1507-1510
-
-
Cao, S.1
Rustum, Y.M.2
Spector, T.3
-
111
-
-
0031060493
-
Dihydropyrimidine dehydrogenase inactivation and 5-fluorouracil pharmacokinetics-allometric scaling of animal data, pharmacokinetics and toxicodynamics of 5-fluorouracil in humans
-
Khor SP, Amyx H, Davis ST, Nelson D, Baccanari DP, Spector T. Dihydropyrimidine dehydrogenase inactivation and 5-fluorouracil pharmacokinetics-allometric scaling of animal data, pharmacokinetics and toxicodynamics of 5-fluorouracil in humans. Cancer Chemother Pharmacol 1997;39:233-8.
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 233-238
-
-
Khor, S.P.1
Amyx, H.2
Davis, S.T.3
Nelson, D.4
Baccanari, D.P.5
Spector, T.6
-
112
-
-
0030888321
-
Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hours continuous infusion in pretreated metastatic colorectal cancer
-
De Gramont A, Vignoud J, Tournigand C, Louvet C, André T, Varette C, et al. Oxaliplatin with high-dose leucovorin and 5-fluorouracil 48-hours continuous infusion in pretreated metastatic colorectal cancer. Eur J Cancer 1997;33:214-9.
-
(1997)
Eur J Cancer
, vol.33
, pp. 214-219
-
-
De Gramont, A.1
Vignoud, J.2
Tournigand, C.3
Louvet, C.4
André, T.5
Varette, C.6
-
113
-
-
0027489763
-
5-ethynyluracil (776C85): A potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil
-
Baccanari DP, Davis ST, Knick VC, Spector T. 5-ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil. Proc Natl Acad Sci USA 1993;90:11064-8.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11064-11068
-
-
Baccanari, D.P.1
Davis, S.T.2
Knick, V.C.3
Spector, T.4
-
114
-
-
0028856765
-
5-ethynyluracil (776C85): Effects on the antitumor activity and pharmacokinetics of tegafur, a prodrug of 5-fluorouracil
-
Cao S, Baccanari DP, Joyner SS, Davis ST, Rustum YM, Spector T. 5-ethynyluracil (776C85): effects on the antitumor activity and pharmacokinetics of tegafur, a prodrug of 5-fluorouracil. Cancer Res 1995;55:6227-30.
-
(1995)
Cancer Res
, vol.55
, pp. 6227-6230
-
-
Cao, S.1
Baccanari, D.P.2
Joyner, S.S.3
Davis, S.T.4
Rustum, Y.M.5
Spector, T.6
-
115
-
-
0028987176
-
5-fluoro-2-pyrimidone, a liver aldehyde oxidase-activated prodrug of 5-fluorouracil
-
Guo X, Lerner-Tung M, Chen XM, Chang CN, Zhu JL, Chang CP, et al. 5-fluoro-2-pyrimidone, a liver aldehyde oxidase-activated prodrug of 5-fluorouracil. Biochem Pharmacol 1995;49:1111-6.
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1111-1116
-
-
Guo, X.1
Lerner-Tung, M.2
Chen, X.M.3
Chang, C.N.4
Zhu, J.L.5
Chang, C.P.6
-
116
-
-
0027163564
-
A phase II study of combination therapy with 5'-deoxy-5-fluorouridine and cisplatin in the treatment of advanced gastric cancer with primary foci
-
Koizumi W, Kurihara M, Sasai T, Yoshida S, Morise K, Imamura A, et al. A phase II study of combination therapy with 5'-deoxy-5-fluorouridine and cisplatin in the treatment of advanced gastric cancer with primary foci. Cancer 1993;72:658-62.
-
(1993)
Cancer
, vol.72
, pp. 658-662
-
-
Koizumi, W.1
Kurihara, M.2
Sasai, T.3
Yoshida, S.4
Morise, K.5
Imamura, A.6
-
117
-
-
0031014627
-
Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy
-
Rougier P, Bugat R, Douillard JY, Culine S, Sue E, Brunet P, et al. Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. J Clin Oncol 1997;15:251-60.
-
(1997)
J Clin Oncol
, vol.15
, pp. 251-260
-
-
Rougier, P.1
Bugat, R.2
Douillard, J.Y.3
Culine, S.4
Sue, E.5
Brunet, P.6
-
118
-
-
0030065613
-
Isozyme specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines
-
Morgan AS, Ciaccio PJ, Tew KD, Kauvar LN. Isozyme specific glutathione S-transferase inhibitors potentiate drug sensitivity in cultured human tumor cell lines. Cancer Chem Pharmacol 1996; 37:363-70.
-
(1996)
Cancer Chem Pharmacol
, vol.37
, pp. 363-370
-
-
Morgan, A.S.1
Ciaccio, P.J.2
Tew, K.D.3
Kauvar, L.N.4
-
119
-
-
0031023615
-
Multifactorial mechanism for the potentiation of cisplatin (CDDP) cytotoxicity by all-trans retinoic acid (ATRA) in human ovarian carcinoma cell lines
-
Caliaro MJ, Vitaux P, Lafon C, Lochon I, Nehme A, Valette A, et al. Multifactorial mechanism for the potentiation of cisplatin (CDDP) cytotoxicity by all-trans retinoic acid (ATRA) in human ovarian carcinoma cell lines. Br J Cancer 1997;75:333-40.
-
(1997)
Br J Cancer
, vol.75
, pp. 333-340
-
-
Caliaro, M.J.1
Vitaux, P.2
Lafon, C.3
Lochon, I.4
Nehme, A.5
Valette, A.6
-
120
-
-
19144361831
-
Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123
-
Fruehauf S, Breems DA, Knaän-Shanzer S, Brouwer KB, Haas R, Löwenberg B, et al. Frequency analysis of multidrug resistance-1 gene transfer into human primitive hematopoietic progenitor cells using the cobblestone area-forming cell assay and detection of vector-mediated P-glycoprotein expression by rhodamine-123. Hum Gene Ther 1996;7:1219-31.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1219-1231
-
-
Fruehauf, S.1
Breems, D.A.2
Knaän-Shanzer, S.3
Brouwer, K.B.4
Haas, R.5
Löwenberg, B.6
-
121
-
-
0029984012
-
In vitro and in vivo liposome mediated gene transfer leads to human MDRI expression in mouse bone marrow progenitor cells
-
Aksentijevich I, Pastan I, Lunardi-Iskandar Y, Gallo RC, Gottesman MM, Thierry AR. In vitro and in vivo liposome mediated gene transfer leads to human MDRI expression in mouse bone marrow progenitor cells. Hum Gene Ther 1996;7:1111-22.
-
(1996)
Hum Gene Ther
, vol.7
, pp. 1111-1122
-
-
Aksentijevich, I.1
Pastan, I.2
Lunardi-Iskandar, Y.3
Gallo, R.C.4
Gottesman, M.M.5
Thierry, A.R.6
-
122
-
-
0030514283
-
In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer
-
Spitz FR, Nguyen D, Skibber JM, Cusack J, Roth JA, Cristiano RJ. In vivo adenovirus-mediated p53 tumor suppressor gene therapy for colorectal cancer. Anticancer Res 1996;16:3415-22.
-
(1996)
Anticancer Res
, vol.16
, pp. 3415-3422
-
-
Spitz, F.R.1
Nguyen, D.2
Skibber, J.M.3
Cusack, J.4
Roth, J.A.5
Cristiano, R.J.6
-
123
-
-
0029057871
-
Manipulation of cell death. The development of novel strategies for the treatment of gastrointestinal disease
-
Watson AJM. Manipulation of cell death. The development of novel strategies for the treatment of gastrointestinal disease. Aliment Pharmacol Ther 1995;9:215-26.
-
(1995)
Aliment Pharmacol Ther
, vol.9
, pp. 215-226
-
-
Watson, A.J.M.1
-
124
-
-
0028718808
-
Mechanisms of acquired resistance to cisplatin
-
Andrews PA. Mechanisms of acquired resistance to cisplatin. Cancer Treat Res 1994;73: 217-48.
-
(1994)
Cancer Treat Res
, vol.73
, pp. 217-248
-
-
Andrews, P.A.1
-
126
-
-
0026406786
-
Interactions between antitumour agents and radiation and the expression of resistance
-
Hill BT. Interactions between antitumour agents and radiation and the expression of resistance. Cancer Treat Rev 1991;18:149-90.
-
(1991)
Cancer Treat Rev
, vol.18
, pp. 149-190
-
-
Hill, B.T.1
-
128
-
-
0029846176
-
Intrinsic and acquired resistance to methotrexate in acute leukemia
-
Gorlick R, Goker E, Trippett T, Waltham M, Banerjee D, Bertino JR. Intrinsic and acquired resistance to methotrexate in acute leukemia. N Engl J Med 1996;335:1041-8.
-
(1996)
N Engl J Med
, vol.335
, pp. 1041-1048
-
-
Gorlick, R.1
Goker, E.2
Trippett, T.3
Waltham, M.4
Banerjee, D.5
Bertino, J.R.6
-
129
-
-
0029939285
-
Current concepts of treatment in medical oncology: New anticancer drugs
-
Unger C. Current concepts of treatment in medical oncology: new anticancer drugs. J Cancer Res Clin Oncol 1996;122:189-98.
-
(1996)
J Cancer Res Clin Oncol
, vol.122
, pp. 189-198
-
-
Unger, C.1
|