Renal Na-Si-1 cotransporter NaSi-1 is inhibited by heavy metals

American Journal of Physiology - Renal Physiology

Volumn 274, Issue 2 43-2, 1998, Pages

  Markovich, Daniel ^a   Knight, David ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Brush border membrane; Nephrotoxicity; Sodium sulfate cotransport; Xenopus laevis oocytes

Indexed keywords

CADMIUM; CARRIER PROTEIN; HEAVY METAL; LEAD; MERCURY; SODIUM ION; SULFUR; CATION TRANSPORT PROTEIN; CHROMIUM; COMPLEMENTARY RNA; COTRANSPORTER; METAL; SODIUM; SODIUM SULFATE COTRANSPORTER; SULFATE;

ANIMAL CELL; ARTICLE; BRUSH BORDER; CONTROLLED STUDY; FEMALE; HEAVY METAL POISONING; KIDNEY TUBULE EPITHELIUM; NEPHROTOXICITY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; TRANSPORT KINETICS; XENOPUS LAEVIS; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; ION TRANSPORT; KINETICS; METABOLISM;

ANIMALS; CADMIUM; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CHROMIUM; FEMALE; ION TRANSPORT; KINETICS; LEAD; MERCURY; METALS; OOCYTES; RNA, COMPLEMENTARY; SODIUM; SULFATES; SYMPORTERS; TRANSFECTION; XENOPUS LAEVIS;

EID: 0031990998     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. 1 cells: mechanisms of injury. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F377-F384, 1993.
2. Anner, B. M, M. Moosmayer, and E. Imesch. Mercury blocks Na-K-ATPase by a ligand-dependent and reversible manner. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F830-F836, 1992.
3. Besseghir, K., and F. Roch-Ramel. Renal excretion of drugs and other xenobiotics. Renal Physiol. 10: 221-241, 1987.
4. 2- transport protein NaSi-1. J. Biol. Chem. 269: 12407-12409, 1994.
5. Campbell, C. E., R. A. Gravel, and G. Worton. Isolation and characterisation of Chinese hamster cell mutants resistant to the cytotoxic effects of chromate. Somat. Cell. Genet. 7: 535-546, 1981.
6. Donaldson, W. E., and S. O. Knowles. Is lead toxicosis a reflection of altered fatty acid composition of membranes? Comp. Biochem. Physiol. C 104: 77-379, 1993.
7. Fukino, H., M. Hirai, Y. M. Hsueh, S. Moriyasu, and Y. Yamane. Mechanism of protection of by zinc against mercuric chloride toxicity in rats: Effects of mercury and zinc on glutathione metabolism. J. Toxicol. Environ. Health 19: 75-89, 1986.
8. Gstraunthaler, G., W. Pfaller, and P. Kotanko. Glutathione depletion and in vitro lipid peroxidation in mercury and maleate induced acute renal failure. Biochem. Pharmacol. 32: 2969-2972, 1983.
9. Herak-Kramberger, C. M., B. Spindler, J. Biber, H. Murer, and I. Sabolic. Renal type II Na/Pi-cotransporter is strongly impaired whereas Na/sulphate-cotransporter and aquaporin 1 are unchanged in cadmium-treated rats. Pflügers Arch. 432: 336-244, 1996.
10. Iturri, S. J., and A. Pena. Heavy metal-induced inhibition of active transport in the rat small intestine in vitro. Interactions with other ions. Comp. Biochem. Physiol. C 84: 363-368, 1986.
11. Langard, S., and T. Norseth. Chromium. In: Handbook on the Toxicology of Metals (2nd ed.), edited by L. Friberg, G. F. Nordberg, and V. Vouk. Amsterdam: Elsevier, 1986, p. 185-210.
12. Lu, Y.-Y., and J.-L. Yang. Long term exposure to chromium (VI) oxide leads to defects in sulfate transport system in Chinese hamster ovary cells. J. Cell. Biochem. 57: 655-665, 1995.
13. Magagnin, S., A. Werner, D. Markovich, V. Sorribas, G. Stange, J. Biber, and H. Murer. Expression cloning of human and rat renal cortex Na/Pi-cotransport. Proc. Natl. Acad. Sci. USA 90: 5979-5983, 1993.
14. Markovich, D., M. Bissig, V. Sorribas, B. Hagenbuch, P. J. Meier, and H. Murer. Expression of rat renal sulfate transport systems in Xenopus laevis oocytes: functional characterization and molecular identification. J. Biol. Chem. 269: 3022-3026, 1994.
15. 2--cotransport. Proc. Natl. Acad. Sci. USA 90: 8073-8077, 1993.
16. Miura, K. A., S. Nagaguma, S. Himeno, and N. Imura. Mercury toxicity. In: Toxicology of Metals. Handbook of Experimental Pharmacology, edited by R. A. Goyer and M. G. Cherian. New York: Springer-Verlag, 1995, vol. 115, p. 163-187.
17. Morris, B. W., A. Blumsohn, S. M. Neil, and T. A. Gray. The trace element chromium: a role in glucose homeostasis. Am. J. Clin. Nutr. 55: 989-991, 1992.
18. Nolan, C. V., and Z. A. Shaikh. Lead nephrotoxicity and associated disorders: biochemical mechanisms. Toxicology 73: 127-146, 1992.
19. 2- cotransporter. Plügers Arch. 428: 217-223, 1994.
20. Piscator, M. The nephropathy of chronic cadmium poisoning. In: Cadmium. Handbook of Experimental Pharmacology, edited by E. C. Foulkes. New York: Springer-Verlag, 1986, vol. 80, p. 179-194.
21. Tallgren, L. G. Inorganic sulfates in relation to the serum thyroxine level and in renal failure. Acta Med. Scand. Suppl. 640: 1-100, 1980.
22. Vacca, C. V., J. D. Hines, and P. W. Hall. The proteinuria of industrial lead intoxication. Environ. Res. 41: 440-446, 1986.
23. i-induced currents through human brush border NaPi-3 cotransporter in Xenopus oocytes. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F926-F930, 1996.
24. Waldegger, S., F. Schmidt, T. Herzer, E. Gulbins, A. Schuster, J. Biber, D. Markovich, H. Murer, A. E. Busch, and F. Lang. Heavy metal mediated inhibition of rBAT induced amino acid transport in Xenopus oocytes. Kidney Int. 47: 1677-1681, 1995.
25. Wetterhahn, K. E., J. W. Hamilton, J. Aiyar, K. M. Borges, and R. Floyd. Mechanism of chromium (VI) carcinogenesis: reactive intermediates and effect on gene expression. Biol. Trace Element Res. 21: 405-411, 1989.
26. Zallups, R. K. Early aspects of the intrarenal distribution of mercury after the intravenous administration of mercuric chloride. Toxicology 79: 215-218, 1993.